Hyalinizing trabecular tumor of the thyroid: A case report

Zhang,Luyao; Ma,Qiang; Shen,Zhixin; Guo,Lu

doi:10.3892/ol.2025.14865

Hyalinizing trabecular tumor of the thyroid: A case report

Authors:
- Luyao Zhang
- Qiang Ma
- Zhixin Shen
- Lu Guo
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Affiliations: Department of Thyroid and Breast Surgery, Affiliated Hospital of Shandong Second Medical University, Weifang, Shandong 261042, P.R. China, Department of Pathology, Sunshine Union Hospital, Weifang, Shandong 261000, P.R. China, Department of Oncology, Affiliated Hospital of Shandong Second Medical University, Weifang, Shandong 261042, P.R. China
Published online on: January 3, 2025 https://doi.org/10.3892/ol.2025.14865
Article Number: 118
Copyright: © Zhang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

A hyalinizing trabecular tumor (HTT), characterized by a trabecular growth pattern and notable hyalinization within the trabeculae, occurs at a rate of ~1%. As patients with HTT may be asymptomatic, accurate diagnosis is a challenge. Due to its resemblance to other tumors, such as papillary thyroid carcinoma and medullary thyroid carcinoma, a precise diagnosis necessitates both pathological and molecular examinations. Additionally, HTT is potentially malignant. The present study described the clinicopathological diagnosis of a patient with HTT; highlighting how an understanding of the clinical and pathological features of HTT is needed to provide an accurate differential diagnosis and thus tailor the treatment approach in order to effectively manage the disease.

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