Open Access

Human parechovirus encephalitis in an immunocompetent adult patient: A case‑report and literature review

  • Authors:
    • Francesca Scirè
    • Davide Vetri
    • Salvatore Di Marca
    • Alessandro Guarneri
    • Alessandro Nigrelli
    • Simone Bongiorno
    • Luigi Guarneri
    • Manuela Ceccarelli
  • View Affiliations

  • Published online on: January 31, 2025     https://doi.org/10.3892/wasj.2025.318
  • Article Number: 30
  • Copyright : © Scirè et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].

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Abstract

Human parechovirus (HPeV) has been identified as the cause of epidemic myalgia in adult patients and as the etiology in severe syndromes, such as myocarditis, pericarditis and encephalitis in children and immunocompromised individuals. The present study describes the case of an immunocompetent adult patient with HPeV. The case‑report was written following CARE guidelines. The present study also provides a brief review of the relevant literature in an aim to raise awareness against HPeV as a rare cause of severe disease in immunocompetent adults. HPeV is a rare cause of disease in immunocompetent adults and can cause permanent sequelae. Care givers and medical professional usually aim for a rapid (7‑14 days) and full recovery. The elderly and individuals with comorbidities in whom the normal functioning of the immune system is altered, such as in those with diabetes and alcohol abuse, should be aware they are at a higher risk for a negative prognosis. 
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May-June 2025
Volume 7 Issue 3

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Spandidos Publications style
Scirè F, Vetri D, Di Marca S, Guarneri A, Nigrelli A, Bongiorno S, Guarneri L and Ceccarelli M: Human parechovirus encephalitis in an immunocompetent adult patient: A case‑report and literature review. World Acad Sci J 7: 30, 2025.
APA
Scirè, F., Vetri, D., Di Marca, S., Guarneri, A., Nigrelli, A., Bongiorno, S. ... Ceccarelli, M. (2025). Human parechovirus encephalitis in an immunocompetent adult patient: A case‑report and literature review. World Academy of Sciences Journal, 7, 30. https://doi.org/10.3892/wasj.2025.318
MLA
Scirè, F., Vetri, D., Di Marca, S., Guarneri, A., Nigrelli, A., Bongiorno, S., Guarneri, L., Ceccarelli, M."Human parechovirus encephalitis in an immunocompetent adult patient: A case‑report and literature review". World Academy of Sciences Journal 7.3 (2025): 30.
Chicago
Scirè, F., Vetri, D., Di Marca, S., Guarneri, A., Nigrelli, A., Bongiorno, S., Guarneri, L., Ceccarelli, M."Human parechovirus encephalitis in an immunocompetent adult patient: A case‑report and literature review". World Academy of Sciences Journal 7, no. 3 (2025): 30. https://doi.org/10.3892/wasj.2025.318