Significance of molecular analyses in the era of personalized tumor therapy

The development of modern techniques of molecular biology has led to great progress in better understanding of complex changes during carcinogenesis in basic research, but parallel application in clinical practice has contributed to better diagnosis of tumors. Today, the examination of molecular markers and genetic analyzes is almost unavoidable when making an accurate diagnosis of a tumor, when assessing the prognosis of a disease, as well as for tumor therapy. All this together has contributed to prolonging overall survival and increasing the quality of life of patients with tumors. Therefore, the aim of this special issue is to show the importance of molecular analysis in various types of tumors and to clearly see where we are today and what else can be done to make diagnosis useful in individual therapy and what can be achieved using various techniques and mathematical models of tumor marker analysis in better patient treatment.

21/12/2024