Journal Articles

Review

Insight into the role of microRNAs in brain tumors (Review)

Alessia Catania, Francesca Maira, Evangelia  Skarmoutsou, Fabio  D'Amico, Roger Abounader, Maria Clorinda Mazzarino

Pages: 605-624 Published online on: 15 December 2011
Review

Genetics and molecular epidemiology of multiple myeloma: The rationale for the IMMEnSE consortium (Review)

Alessandro Martino, Juan Sainz, Gabriele Buda, Krzysztof Jamroziak, Rui Manuel Reis, Ramón García-Sanz, Manuel Jurado, Rafael Ríos, Zofia Szemraj-Rogucka, Herlander Marques, Fabienne Lesueur, Victor Moreno, Enrico Orciuolo, Federica Gemignani, Stefano Landi, Anna Maria Rossi, Charles Dumontet, Mario Petrini, Daniele Campa, Federico Canzian

Pages: 625-638 Published online on: 06 December 2011
Review Open Access

Gene alterations in the PI3K/PTEN/AKT pathway as a mechanism of drug-resistance (Review)

Sameh Hafsi, Franca Maria Pezzino, Saverio Candido, Giovanni Ligresti, Demetrios A. Spandidos, Zohra Soua, James A. McCubrey, Salvatore Travali, Massimo Libra

Pages: 639-644 Published online on: 20 December 2011
Article Open Access

Identification of a methylation hotspot in the death receptor Fas/CD95 in bladder cancer

C. J. Watson, H. O'Kane, P. Maxwell, O. Sharaf, I. Petak, P. L. Hyland, D. O'Rouke, J. McKnight, P. Canning, K. Williamson

Pages: 645-654 Published online on: 04 November 2011
Article Open Access

GATA-binding protein 1 is a novel transcription regulator of peroxiredoxin 5 in human breast cancer cells

Min Ji Seo, Xiyuan Liu, Minsun Chang, Jong Hoon Park

Pages: 655-664 Published online on: 20 October 2011
Article Open Access

The CD49d+/high subpopulation from isolated human breast sarcoma spheres possesses tumor-initiating ability

Kyung-Min Lee, Wonshik Han, Jong Bin Kim, Incheol Shin, Eunyoung Ko, In Ae Park, Dong Sup Lee, Kuenhee Oh, Dong-Young Noh

Pages: 665-672 Published online on: 08 December 2011
Article Open Access

The role of the tumor suppressor RUNX3 in giant cell tumor of the bone

Ya-Xin Han, De-Yong Liang

Pages: 673-678 Published online on: 04 November 2011
Article Open Access

PPARγ potentiates anticancer effects of gemcitabine on human pancreatic cancer cells

Hironori Koga, Karuppaiyah Selvendiran, Ramadoss Sivakumar, Takafumi Yoshida, Takuji Torimura, Takato Ueno, Michio Sata

Pages: 679-685 Published online on: 20 October 2011
Article

Aberrant methylation of the Pleckstrin and Sec7 domain-containing gene is implicated in ulcerative colitis-associated carcinogenesis through its inhibitory effect on apoptosis

Shinichiro Okada, Koichi Suzuki, Kato Takaharu, Hiroshi Noda, Hidenori Kamiyama, Takafumi Maeda, Masaaki Saito, Kei Koizumi, Yuichiro Miyaki, Fumio Konishi

Pages: 686-694 Published online on: 13 October 2011
Article

Transcriptional and post-transcriptional regulation of βIII-tubulin protein expression in relation with cell cycle-dependent regulation of tumor cells

Masahiko Shibazaki, Chihaya Maesawa, Kiyomi Akasaka, Shuya  Kasai, Shinji Yasuhira, Kiminori Kanno, Ikue Nakayama, Toru Sugiyama, Go Wakabayasi, Tomoyuki Masuda, Nozomu Mori

Pages: 695-702 Published online on: 08 December 2011
Article

Increased ERK activation and cellular drug accumulation in the enhanced cytotoxicity of folate receptor-targeted liposomal carboplatin

Anumita Chaudhury, Bee Jee Tan, Surajit Das, Gigi N.C. Chiu

Pages: 703-710 Published online on: 11 November 2011
Article

Differential effects of PXD101 (belinostat) on androgen-dependent and androgen-independent prostate cancer models

Giovanni Luca Gravina, Francesco Marampon, Ilaria Giusti, Eleonora Carosa, Stefania Di Sante, Enrico Ricevuto, Vincenza Dolo, Vincenzo Tombolini, Emmanuele A Jannini, Claudio Festuccia

Pages: 711-720 Published online on: 23 November 2011
Article

Identification and validation of a gene expression signature that predicts outcome in malignant glioma patients

Atsushi Kawaguchi, Naoki Yajima, Yoshihiro Komohara, Hiroshi Aoki, Naoto Tsuchiya, Jumpei Homma, Masakazu Sano, Manabu Natsumeda, Takeo Uzuka, Akihiko Saitoh, Hideaki Takahashi, Yuko Sakai, Hitoshi Takahashi, Yukihiko Fujii, Tatsuyuki Kakuma, Ryuya Yamanaka

Pages: 721-730 Published online on: 21 October 2011
Article

A novel synthetic 2-(3-methoxyphenyl)-6,7-methylenedioxoquinolin-4-one arrests the G2/M phase arrest via Cdc25c and induces apoptosis through caspase- and mitochondria-dependent pathways in TSGH8301 human bladder cancer cells

Shu-Chun Hsu, Chien-Chih Yu, Jai-Sing Yang, Kuang-Chi Lai, Shin-Hwar Wu, Jen-Jyh Lin, Jehn-Hwa Kuo, Su-Tso Yang, Ching-Che Huang, Sheng-Chu Kuo, Jing-Gung Chung

Pages: 731-738 Published online on: 21 October 2011
Article

Methylation profiling in non-small cell lung cancer: Clinical implications

Alberto Morán, Tamara Fernández-Marcelo, Juan Carro, Carmen  De Juan, Irene Pascua, Jacqueline Head, Ana Gómez, Florentino Hernando, Antonio-José Torres, Manuel Benito, Pilar Iniesta

Pages: 739-746 Published online on: 07 November 2011
Article

microRNA-150 inhibits human CD133-positive liver cancer stem cells through negative regulation of the transcription factor c-Myb

Jun Zhang, Na Luo, Yi Luo, Zhiping Peng, Tao Zhang, Shaolin Li

Pages: 747-756 Published online on: 24 October 2011
Article

Oncolytic herpes simplex virus treatment of metastatic breast cancer

Jiani Wang, Pan Hu, Musheng Zeng, Samuel D. Rabkin, Renbin Liu

Pages: 757-763 Published online on: 21 November 2011
Article

Therapeutical doses of temozolomide do not impair the function of dendritic cells and CD8+ T cells

Xun Xu, Florian Stockhammer, Anita Schmitt, Rosaely Casalegno-Garduno, Anne Enders, Jiju Mani, Carl Friedrich Classen, Michael Linnebacher, Mathias Freund, Michael Schmitt

Pages: 764-772 Published online on: 23 November 2011
Article

A phase II study of docetaxel weekly in combination with carboplatin every three weeks as first line chemotherapy in stage IIB-IV epithelial ovarian cancer: Neurological toxicity and quality-of-life evaluation

Bengt Sorbe, Marianne Graflund, Lisa Nygren, György Horvath, Marie Swahn, Karin Boman, René Bangshöj, Margareta Lood, Henric Malmström

Pages: 773-781 Published online on: 07 December 2011
Article

Two initiation sites of early detection of colon cancer, revealed by localization of pERK1/2 in the nuclei or in aggregates at the perinuclear region of tumor cells Retraction in /ijo/41/5/1887

Abraham Amsterdam, Elias Shezen, Calanit Raanan, Letizia Schreiber, Yasmin Slilat, Yakov Fabrikant, Ehud Melzer, Rony Seger

Pages: 782-788 Published online on: 22 November 2011
Article

DNA binding protein A expression and methylation status in hepatocellular carcinoma and the adjacent tissue

Mahmut Yasen, Gulanbar Obulhasim, Kazunori Kajino, Kaoru Mogushi, Hiroshi Mizushima, Shinji Tanaka, Hiroshi Tanaka, Okio Hino, Shigeki Arii

Pages: 789-797 Published online on: 06 December 2011
Article

Intrinsic gemcitabine resistance in a novel pancreatic cancer cell line is associated with cancer stem cell-like phenotype

Gang Hu, Fu Li, Kedong Ouyang, Fubo Xie, Xuzhen Tang, Ke Wang, Sufang Han, Zhenzhou Jiang, Minghua Zhu, Danyi Wen, Xiaoran Qin, Luyong Zhang

Pages: 798-806 Published online on: 07 November 2011
Article

NO donor and MEK inhibitor synergistically inhibit proliferation and invasion of cancer cells

Satoshi Furuhashi, Hiroki Sugita, Hiroshi Takamori, Kei Horino, Osamu Nakahara, Hirohisa Okabe, Keisuke Miyake, Hiroshi Tanaka, Toru Beppu, Hideo Baba

Pages: 807-815 Published online on: 24 October 2011
Article

Brassinin induces G1 phase arrest through increase of p21 and p27 by inhibition of the phosphatidylinositol 3-kinase signaling pathway in human colon cancer cells

Yasuyuki Izutani, Shingo Yogosawa, Yoshihiro Sowa, Toshiyuki Sakai

Pages: 816-824 Published online on: 27 October 2011
Article Open Access

Performance evaluation of the DNA methylation biomarker SHOX2 for the aid in diagnosis of lung cancer based on the analysis of bronchial aspirates

Dimo Dietrich, Christoph Kneip, Olaide Raji, Triantafillos Liloglou, Anke Seegebarth, Thomas Schlegel, Nadja Flemming, Sebastian Rausch, Jürgen Distler, Michael Fleischhacker, Bernd Schmidt, Thomas Giles, Martin Walshaw, Chris Warburton, Volker Liebenberg, John K. Field

Pages: 825-832 Published online on: 16 November 2011
Article

Serum IL10, IL12 and circulating CD4+CD25high T regulatory cells in relation to long-term clinical outcome in head and neck squamous cell carcinoma patients

Victoria L. Green, Ekpemi Irune, Amit Prasai, Osama Alhamarneh, John Greenman, Nicholas D. Stafford

Pages: 833-839 Published online on: 10 November 2011
Article

Newcastle disease virus induces pro-inflammatory conditions and type I interferon for counter-acting Treg activity

Philippe Fournier, Annette Arnold, Holger Wilden, Volker Schirrmacher

Pages: 840-850 Published online on: 16 November 2011
Article

Recombinant human MDM2 oncoprotein shows sequence composition selectivity for binding to both RNA and DNA

Christine Challen, John J. Anderson, Zofia   M.A. Chrzanowska‑Lightowlers, Robert N. Lightowlers, John Lunec

Pages: 851-859 Published online on: 21 November 2011
Article

Transcriptional analysis of CXCR4, DNMT3A, DNMT3B and DNMT1 gene expression in primary advanced uterine cervical carcinoma

Michał W. Łuczak, Andrzej Roszak, Piotr Pawlik, Helena Kędzia, Witold Kędzia, Blanka Malkowska-Walczak, Margarita Lianeri, Paweł P. Jagodziński

Pages: 860-866 Published online on: 01 September 2011
Article

Statins exhibit anticancer effects through modifications of the pAkt signaling pathway

Erica Miraglia, Johan Högberg, Ulla Stenius

Pages: 867-875 Published online on: 06 October 2011
Article

AKT inhibition by triciribine alone or as combination therapy for growth control of gastroenteropancreatic neuroendocrine tumors

Christoph R. Gloesenkamp, Bianca Nitzsche, Matthias Ocker, Pietro Di Fazio, Karl Quint, Björn Hoffmann, Hans Scherübl, Michael Höpfner

Pages: 876-888 Published online on: 07 November 2011
Article

Identification of GABRA1 and LAMA2 as new DNA methylation markers in colorectal cancer

Sunwoo Lee, Taejeong Oh, Hyuncheol Chung, Sunyoung Rha, Changjin Kim, Youngho Moon, Benjamin D. Hoehn, Dongjun Jeong, Seunghoon Lee, Namkyu Kim, Chanhee Park, Miae Yoo, SungWhan An

Pages: 889-898 Published online on: 25 October 2011
Journal Cover

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March 2012
Volume 40 Issue 3

Print ISSN: 1019-6439
Online ISSN: 1791-2423

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