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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March-April 2011 Volume 4 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Role of genetic polymorphisms and mutations in colorectal cancer therapy (Review)

Marco Aiello, Nadia Vella, Calogero Cannavò, Aurora Scalisi, Demetrios A. Spandidos, Giuseppe Toffoli, Angela Buonadonna, Massimo Libra, Franca Stivala
Pages: 203-208
Published online on: 16 December 2010

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Article

Antibodies against swine influenza virus neutralize the pandemic influenza virus A/H1N1

Masaya Tsukamoto, Satoshi Hiroi, Kazuhide Adachi, Hidenori Kato, Marie Inai, Itsuro Konishi, Masaru Tanaka, Ryouhei Yamamoto, Masaki  Sawa, Ekowati Handharyani, Yasuhiro Tsukamoto
Pages: 209-214
Published online on: 03 January 2011

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Article

Estrogen receptor α induces down-regulation of PTEN through PI3-kinase activation in breast cancer cells

Eun-Mi Noh, Young-Rae Lee, Kee-Oh Chay, Eun-Yong Chung, Sung Hoo Jung, Jong-Suk Kim, Hyun Jo Youn
Pages: 215-219
Published online on: 03 January 2011

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Article

Emodin potentiates the antitumor effects of gemcitabine in pancreatic cancer cells via inhibition of nuclear factor-κB

An Liu, Hui Chen, Hongfei Tong, Sheng Ye, Maixuan Qiu, Zhaohong Wang, Wei Tan, Jinxiang Liu, Shengzhang Lin
Pages: 221-227
Published online on: 03 January 2011

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Article

Skeletal muscle tissue from the Goto-Kakizaki rat model of type-2 diabetes exhibits increased levels of the small heat shock protein Hsp27

Edel Mullen, Elaine O’Reilly, Kay Ohlendieck
Pages: 229-236
Published online on: 25 January 2011

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Article

Novel IRF6 mutations in Honduran Van Der Woude syndrome patients

Andrew C. Birkeland, Yuna Larrabee, David T. Kent, Carlos  Flores, Gloria H. Su, Joseph H. Lee, Joseph Haddad
Pages: 237-241
Published online on: 11 January 2011

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Article

Unbalanced MMP/TIMP-1 expression during the development of experimental pulmonary fibrosis with acute paraquat poisoning

Bo-Liang Wang, Yan-Yang Tu, Jian-Fang Fu, Yue-Xia Zhong, Guo‑Qiang Fu, Xiao-Xi Tian, Li-He Wang, Li Gong, Qin-You Ren
Pages: 243-248
Published online on: 14 January 2011

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Article

Overexpression of angiotensin II type 2 receptor suppresses neointimal hyperplasia in a rat carotid arterial balloon injury model

Bing Tang, Shuangtao Ma, Yongjian Yang, Dachun Yang, Jinsong Chen, Xiaohua Su, Yan Tan, Meiqin Sun, De Li
Pages: 249-254
Published online on: 25 January 2011

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Change of telomere length in angiotensin ii-induced human glomerular mesangial cell senescence and the protective role of losartan

Xin Feng, Lining Wang, Yao Li
Pages: 255-260
Published online on: 25 January 2011

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Article

A novel adriamycin analogue derived from marine microbes induces apoptosis by blocking Akt activation in human breast cancer cells

Jie Yuan, Zhenjian He, Jueheng Wu, Yongcheng Lin, Xun Zhu
Pages: 261-265
Published online on: 25 January 2011

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Detection of human metapneumovirus in infants with acute respiratory tract infection

Ioannis N. Mammas, Chryssie Koutsaftiki, Elisabeth Nika, Fotini Vagia, Apostolos Zaravinos, Kostas N. Priftis, Aliki Voyatzi, Maria Theodoridou, Nikolaos Myriokefalitakis, Demetrios A. Spandidos
Pages: 267-271
Published online on: 03 January 2011

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Article

Myricetin induces G2/M phase arrest in HepG2 cells by inhibiting the activity of the cyclin B/Cdc2 complex

Xiao-Hong Zhang, Zu-Quan Zou, Chen-Wei Xu, Ying-Zhuo Shen, Duo Li
Pages: 273-277
Published online on: 05 January 2011

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Article

Three cases of Hb Q-H disease found in a Cantonese family

Chaohui Hu, Ling Zhang, Jianghu Pan, Zengyu Zeng, Saixiang Zhen, Ju Fang, Qingyi Zhu
Pages: 279-281
Published online on: 05 January 2011

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Article

Interleukin-6 -634C>G polymorphism in hypertensive patients with and without left ventricular hypertrophy

Feng Chen, Jing Guo, Shu-Ping Gao, Chu Chen, Yun-Feng Guo, Le Gui, Hai-Hua Geng, Li-Jun Ge, Jian-Hua Zhu, Min Pan
Pages: 283-289
Published online on: 03 January 2011

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Activity of 5-HT1A receptor is involved in neuronal apoptosis of the amygdala in a rat model of post-traumatic stress disorder

Hong Liu, Hai-Tao Wang, Fang Han, Yu-Xiu Shi
Pages: 291-295
Published online on: 03 January 2011

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(-)-Epigallocatechin gallate inhibits thyroid hormone‑stimulated osteocalcin synthesis in osteoblasts

Kenji Kato, Takanobu Otsuka, Seiji Adachi, Rie Matsushima-Nishiwaki, Hideo Natsume, Osamu Kozawa, Haruhiko Tokuda
Pages: 297-300
Published online on: 11 January 2011

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Differentially expressed genes in Men1 knockout and wild‑type embryoid bodies for pancreatic islet development

Hong-Li Zhang, Wen-Yi Li, Cui-Ping Zhang, Ya-Xin Zhu, Ling Wu, Hong-Mei Long, Guo Li, Min Luo
Pages: 301-305
Published online on: 03 January 2011

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Article

STAT3 enhances intracellular Fas-mediated apoptotic signals in HHUA human endometrial epithelial cells

Tetsuji Tanaka, Tao Bai, Hirotoshi Utsunomiya, Takahiro Fukumoto, Kazunori Yukawa
Pages: 307-312
Published online on: 12 January 2011

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Patrinia scabiosaefolia extract suppresses proliferation and promotes apoptosis by inhibiting the STAT3 pathway in human multiple myeloma cells

Jun Peng, Youqin Chen, Jiumao Lin, Qunchuan Zhuang, Wei Xu, Zhenfeng Hong, Thomas J. Sferra
Pages: 313-318
Published online on: 03 January 2011

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Article

Progesterone inhibits inflammatory response pathways after permanent middle cerebral artery occlusion in rats

Jianping Wang, Yuanzheng Zhao, Chunling Liu, Chao Jiang, Chunyan Zhao, Zhongjun Zhu
Pages: 319-324
Published online on: 05 January 2011

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Article

Sulforaphane blocks hypoxia-mediated resistance to TRAIL-induced tumor cell death

Jae-Kyo Jeong, Myung-Hee Moon, Jae-Suk Seo, Jae-Won Seol, You-Jin Lee, Sang-Youel Park
Pages: 325-330
Published online on: 11 January 2011

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Mutations of the Connexin 26 gene in families with non-syndromic hearing loss

Walid Al-Achkar, Faten Moassass, Bassel Al-Halabi, Ayman Al-Ablog
Pages: 331-335
Published online on: 25 January 2011

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Inhibitory effect of esculetin on migration, invasion and matrix metalloproteinase-9 expression in TNF-α-induced vascular smooth muscle cells

Se-Jung Lee, Ung-Soo Lee, Wun-Jae Kim, Sung-Kwon Moon
Pages: 337-341
Published online on: 05 January 2011

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Article

Knockdown of c-Met inhibits cell proliferation and invasion and increases chemosensitivity to doxorubicin in human multiple myeloma U266 cells in vitro

Wenzhong Que, Junmin Chen
Pages: 343-349
Published online on: 14 January 2011

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Article

Preventive role of Propofol in hypoxia/reoxygenation‑induced apoptotic H9c2 rat cardiac myoblast cell death

Seonmin Lee, Kiyoon Kim, Yun Hong Kim, Min Hyung Chung, Insug Kang, Joohun Ha, Wonchae Choe
Pages: 351-356
Published online on: 25 January 2011

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Article

Gefitinib induces mitochondrial-dependent apoptosis in Saccharomyces cerevisiae

Jing Wu, Rou Min, Minchen Wu, Wei Chen
Pages: 357-362
Published online on: 18 January 2011

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Article

Chondroitin synthases I, II, III and chondroitin sulfate glucuronyltransferase expression in colorectal cancer

Dimitrios Kalathas, Dimitrios A. Theocharis, Dimitrios Bounias, Dora Kyriakopoulou, Nikoletta Papageorgakopoulou, Michael S. Stavropoulos, Demitrios H. Vynios
Pages: 363-368
Published online on: 25 January 2011

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Article

IL-10 expression is regulated by HPV E2 protein in cervical cancer cells

V. H. Bermúdez-Morales, O. Peralta-Zaragoza, J. M. Alcocer‑González, J. Moreno, V. Madrid-Marina
Pages: 369-375
Published online on: 25 January 2011

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Article

Expression of β-catenin and cyclin D1 in epidermal stem cells of diabetic rats

Qing-Ling Zhong, Fan-Rong Liu, De-Wu Liu, Yan Peng, Xiang-Rong Zhang
Pages: 377-381
Published online on: 25 January 2011

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Article Open Access

Aberrant expression of let-7a miRNA in the blood of non-small cell lung cancer patients

Hye Cheol Jeong, Eun Kyung Kim, Ji Hyun Lee, Han Na Yoo, Jin Kyeoung Kim
Pages: 383-387
Published online on: 25 January 2011

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Journal Cover
March-2026 Volume 33 Issue 3

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article

CTRP4 ameliorates dexamethasone‑induced insulin resistance through the IRS‑1/PI3K/AKT pathway in 3T3‑L1 adipocytes

Maireyanmu Rouzi, Xi Sun, Luguang Sheng, Bilin Xu, Tao Lei, Jun Lu, Jie Gao
Article Number: 101
Published online on: 27 January 2026

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PTUPB, a soluble epoxide hydrolase/cyclooxygenase‑2 dual inhibitor, reduces endothelial‑to‑mesenchymal transition and improves doxorubicin‑induced vascular and cardiac toxicity

Hevna Dhulkifle, Lubna Therachiyil, Maram H. Hasan, Shahd M. Younis, Nizar A. Al‑Shar'i, Huseyin C. Yalcin, Zaid H. Maayah
Article Number: 100
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] miR‑367 enhances the proliferation and invasion of cutaneous malignant melanoma by regulating phosphatase and tensin homolog expression

Jianwen Long, Jing Luo, Xuwen Yin
Article Number: 99
Published online on: 26 January 2026

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Advances in the mechanisms of the NLRP3 inflammasome in sepsis‑induced cardiomyopathy and targeted therapeutic studies 
(Review)

Yifei Chen, Zhaohui Zhang, Gaosheng Zhou
Article Number: 98
Published online on: 22 January 2026

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HMGN2 induces pyroptosis in tumour cells by modulating the STT3B/PD‑L1/caspase‑1/GSDMD axis

Wenwen Han, Hongli Chen, Bomiao Cui, Jiao Chen, Ping Zhang, Yun Feng
Article Number: 97
Published online on: 22 January 2026

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Naringin ameliorates intestinal injury in ulcerative colitis model mice by modulating the JAK2/STAT3 signaling pathway

Miaomiao Wu, Yating An, Yongmin Li, Wei He, Ying Wang, Yaqi Wang, Caixia Wu
Article Number: 96
Published online on: 22 January 2026

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Review

PDX1 in human cancers: Molecular mechanisms, dual roles and clinical implications (Review)

Chen Zhou, Yifei Wang, Jie Zhao, Yantao Yang, Yuhang Yuan, Xiaochen Hou, Yu Tang, Lianhua Ye
Article Number: 95
Published online on: 22 January 2026

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Retraction Open Access

[Retracted] Autophagy flux inhibition mediated by celastrol sensitized lung cancer cells to TRAIL‑induced apoptosis via regulation of mitochondrial transmembrane potential and reactive oxygen species

Uddin Md Nazim, Honghua Yin, Sang-Youel Park
Article Number: 94
Published online on: 19 January 2026

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Converting ‘cold’ to ‘hot’ hepatocellular carcinoma for improved immunotherapy (Review)

Ching-Hua Hsieh, Pei-Chin Chuang
Article Number: 93
Published online on: 15 January 2026

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Pathological mechanism of ferroptosis in a rat model of α‑naphthyl isothiocyanate‑induced chronic cholestasis

Zhen Guo, Jiaxuan Wang, Yiwen Wang, Xinzhu Liu, Yubing Xia, Ping Liu, Li Qi, Jia Liu, Xiaoning Wang
Article Number: 92
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] Role of hypoxia‑inducible factor‑1α and CD146 in epidermal growth factor receptor‑mediated angiogenesis in salivary gland adenoid cystic carcinom

Wei-Ming Wang, Zhi-Li Zhao, Wen-Feng Zhang, Yi-Fang Zhao, Lu Zhang, Zhi-Jun Sun
Article Number: 91
Published online on: 13 January 2026

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Klebsiella pneumoniae and pyogenic liver abscess: Emerging clinical threats, virulence mechanisms and therapeutic strategies (Review)

Gulam Mustafa Hasan, Taj Mohammad, Sobia Zaidi, Anas Shamsi, Sukhwinder Singh Sohal, Md. Imtaiyaz Hassan
Article Number: 90
Published online on: 13 January 2026

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Collagen III regulates the termination of liver regeneration by suppressing hepatocyte proliferation and promoting functional recovery

Haiyang Peng, Zhiyong Chen, Qiwei Zhang, Yuezhou Zhang, Peng Yang, Jianping Gong, Andong Zhao
Article Number: 89
Published online on: 13 January 2026

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Application of extracellular vesicles in the diagnosis and treatment of chronic obstructive pulmonary disease (Review)

Yixin Zhang, Tong Ren, Jianbo Xue, Yan Yu, Xianqiang Zhou, Xiaoyi Hu, Wenyi Yu, Zhancheng Gao, Cuiling Feng
Article Number: 88
Published online on: 13 January 2026

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Cigarette smoke combined with Klebsiella pneumoniae induce damage to the air‑blood barrier in chronic obstructive pulmonary disease rats via the MAPK/NF‑κB/IκBα pathway

Yange Tian, Kexin Xu, Ruilong Lu, Kangchen Li, Xuejie Shao, Yixi Liao, Yakun Zhao, Zhiguang Qiu, Haoran Dong, Xuefang Liu
Article Number: 87
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] 8‑bromo‑7‑methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin‑sensitive and resistant ovarian cancer cells

Qing Ding, Yi Chen, Qing Zhang, Yanling Guo, Zhi Huang, Liqing Dai, Sudan Cao
Article Number: 86
Published online on: 12 January 2026

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Anxiety‑induced overactive bladder: The role of oxidative stress and NF‑κB signaling pathway with Hsp90 as a potential biomarker

Zhipeng Zhou, Lina Xu, Han Wu, Huaishan Hong
Article Number: 85
Published online on: 12 January 2026

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Echinacoside alleviates asthenozoospermia by upregulating Sox5‑mediated transcriptional activation of the CatSper gene

Zi-Run Jin, Yong-Wei Huo, Bo-Heng Liu, Hong Tian, Shuo Yuan, Yue Tian, Ke Xi, Jie Cai, Hui Jiang, Yong Jiang, Guo-Gang Xing
Article Number: 84
Published online on: 12 January 2026

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Artemisiae Scopariae Herba (Yinchen) suppresses ferroptosis in mice with osteoporosis via the Nrf2/Slc7a11/Gpx4 pathway

Pei Li, Xinyu Wan, Wenjie Li, Ding Cheng, Ying Yang, Yuhan Wang, Ruyuan Zhu, Yanjing Chen, Haixia Liu, Zhiguo Zhang
Article Number: 83
Published online on: 12 January 2026

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Prolyl hydroxylase domain proteins: Localization, regulation, function and their role in erythropoiesis (Review)

Yan Hou, Zhao-Hua Zhang, Wen-Qian Li, Guo-Xiong Han, Kuo Shen, You-Bang Xie
Article Number: 82
Published online on: 12 January 2026

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Therapeutic potential of saponins for allergic rhinitis: Molecular mechanisms and clinical perspectives (Review)

Bing-Yu Liang, Zi-Yue Fu, Fen-Fen Li, Ping-Ting Zhou, Zi-Hui Xie, Ke Han, Yan-Xun Han, Shan-Wen Chen, Yi Zhao, Hai-Feng Pan, Ye-Hai Liu, Yu-Chen Liu
Article Number: 81
Published online on: 07 January 2026

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Interleukin‑6 and ischemic stroke: From mechanisms to clinical prospects (Review)

Xinyue Wang, Xiaohang Zhang, Jianing Lin, Ping Lin
Article Number: 80
Published online on: 05 January 2026

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Preliminary exploration of the putative function of SF3A2 in clear cell renal cell carcinoma

Ru Chen, Jie Xu
Article Number: 79
Published online on: 05 January 2026

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Retraction Open Access

[Retracted] TIPE‑2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3‑kinase/AKT signaling pathway

Lin Wang, Chen Chen, Shuzhi Feng, Jianli Tian
Article Number: 78
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 33 Issue 4

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Circular RNAs in intervertebral disc degeneration: Current insights into mechanisms and therapeutic potentials (Review)

Luyan Wang, Ke Yang, Houjun Zhu, Dachuan Wang, Feng Wang, Xianfa Du
Article Number: 111
Published online on: 05 February 2026

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T‑cadherin and its impact on human diseases (Review)

Yan Song, Xinyi Wang, Yunfei Bian
Article Number: 110
Published online on: 05 February 2026

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Review

CD20 monoclonal antibody‑rituximab for the treatment of diffuse alveolar hemorrhage in children (Review)

Xiaobo Zhang, Xiao Wu, Yan Li, Guangmin Nong
Article Number: 109
Published online on: 05 February 2026

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N6‑methyladenosine reader insulin‑like growth factor 2 mRNA‑binding protein 2 promotes abnormal proliferation of colonic epithelial cells in type 2 diabetes mellitus by regulating midkine

Jieyao Li, Qingsheng Xie, Jihao Xu
Article Number: 108
Published online on: 04 February 2026

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Expression of Concern Open Access

[Expression of Concern] Curcumin suppresses breast tumor angiogenesis by abrogating osteopontin‑induced VEGF expression

Goutam Chakraborty, Shalini Jain, Smita Kale, Remya Raja, Santosh Kumar, Rosalin Mishra, Gopal C. Kundu
Article Number: 107
Published online on: 04 February 2026

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Research status and molecular mechanisms of disulfidptosis in cardiovascular diseases (Review)

Xiao Jin, Zelin Cheng, Xinyue Ding, Zongjun Liu
Article Number: 106
Published online on: 03 February 2026

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Role and mechanism of tetrahedral DNA nanostructures in the repair of urethral injury in rats

Caifen Guo, Jian Li
Article Number: 105
Published online on: 02 February 2026

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[Retracted] MicroRNA‑4500 suppresses tumor progression in non‑small cell lung cancer by regulating STAT3

Zhi-Ying Li, Zi-Zhou Zhang, Hui Bi, Qiu-Di Zhang, Su-Juan Zhang, Lin Zhou, Xiao-Qin Zhu, Jun Zhou
Article Number: 104
Published online on: 02 February 2026

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Integrative bioinformatics and experimental analysis reveals FRA1 as a key mediator of tubulointerstitial inflammation in lupus nephritis

Wenpeng Ni, Jialin He, Zhouyu Zeng, Jialong Ke, Runpei Lin, Jianming Peng, Kunyi Deng, Lijuan Wen, Yanhui Chen, Chilun Zhang, Yanfen Li, Guanghong Gu
Article Number: 103
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] Resveratrol improves neurological outcome and neuroinflammation following spinal cord injury through enhancing autophagy involving the AMPK/mTOR pathway

Hong-Yu Meng, De-Cheng Shao, Han Li, Xiao-Dan Huang, Guang Yang, Bing Xu, Hai-Yun Niu
Article Number: 102
Published online on: 28 January 2026

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