Journal Articles
Review
Role of DLC1 tumor suppressor gene and MYC oncogene in pathogenesis of human hepatocellular carcinoma: Potential prospects for combined targeted therapeutics (Review)
Drazen B. Zimonjic, Nicholas C. Popescu
Pages: 393-406 Published online on: 10 May 2012
Review
Cannabinoid-associated cell death mechanisms in tumor models (Review)
Giuseppe Calvaruso, Ornella Pellerito, Antonietta Notaro, Michela Giuliano
Pages: 407-413 Published online on: 14 May 2012
Article
Barrett's esophagus and esophageal cancer: An overview
Vincenza Conteduca, Domenico Sansonno, Giuseppe Ingravallo, Stefania Marangi, Sabino Russi, Gianfranco Lauletta, Franco Dammacco
Pages: 414-424 Published online on: 17 May 2012
Article
Synergistic activity of the mTOR inhibitor ridaforolimus and the antiandrogen bicalutamide in prostate cancer models
Rachel M. Squillace, David Miller, Scott D. Wardwell, Frank Wang, Tim Clackson, Victor M. Rivera
Pages: 425-432 Published online on: 18 May 2012
Article
Endothelial protein C receptor expressed by ovarian cancer cells as a possible biomarker of cancer onset
Elodie Ducros, Shahsoltan Mirshahi, Dalel Azzazene, Sophie Camilleri-Broët, Eliane Mery, Halema Al Farsi, Hamda Althawadi, Samaher Besbess, Jean Chidiac, Eric Pujade-Lauraine, Amu Therwath, Jeannette Soria, Massoud Mirshahi
Pages: 433-440 Published online on: 18 May 2012
Article
Expression and role of nestin in human cervical intraepithelial neoplasia and cervical cancer
Atsuki Sato, Toshiyuki Ishiwata, Yoko Matsuda, Tetsushi Yamamoto, Hirobumi Asakura, Toshiyuki Takeshita, Zenya Naito
Pages: 441-448 Published online on: 10 May 2012
Article
Antitumor activity of MEK and PI3K inhibitors against malignant pleural mesothelioma cells in vitro and in vivo
Seigo Miyoshi, Hironobu Hamada, Naohiko Hamaguchi, Aki Kato, Hitoshi Katayama, Kazunori Irifune, Ryoji Ito, Tatsuhiko Miyazaki, Takafumi Okura, Jitsuo Higaki
Pages: 449-456 Published online on: 08 May 2012
Article
The role of hepatic stellate cells in the regulation of T-cell function and the promotion of hepatocellular carcinoma
Wenxiu Zhao, Weixue Su, Penghao Kuang, Lei Zhang, Jianming Liu, Zhenyu Yin, Xiaomin Wang
Pages: 457-464 Published online on: 24 May 2012
Article
Depolarization potentiates TRAIL-induced apoptosis in human melanoma cells: Role for ATP-sensitive K+ channels and endoplasmic reticulum stress
Yoshihiro Suzuki, Toshio Inoue, Mayumi Murai, Miki Suzuki‑Karasaki, Toyoko Ochiai, Chisei Ra
Pages: 465-475 Published online on: 17 May 2012
Article
The role of human peritoneal mesothelial cells in the fibrosis and progression of gastric cancer
Tomoya Tsukada, Sachio Fushida, Shinichi Harada, Yasumichi Yagi, Jun Kinoshita, Katsunobu Oyama, Hidehiro Tajima, Hideto Fujita, Itasu Ninomiya, Takashi Fujimura, Tetsuo Ohta
Pages: 476-482 Published online on: 18 May 2012
Article
The clinical impact of breast scintigraphy acquired with a breast specific γ-camera (BSGC) in the diagnosis of breast cancer: Incremental value versus mammography
Angela Spanu, Daniela Sanna, Francesca Chessa, Alessandra Manca, Pierina Cottu, Alessandro Fancellu, Susanna Nuvoli, Giuseppe Madeddu
Pages: 483-489 Published online on: 24 May 2012
Article
Genome-wide screening for methylation-silenced genes in colorectal cancer
Ahmed Khamas, Toshiaki Ishikawa, Kaoru Mogushi, Satoru Iida, Megumi Ishiguro, Hiroshi Tanaka, Hiroyuki Uetake, Kenichi Sugihara
Pages: 490-496 Published online on: 30 May 2012
Article
Association between common genetic variant of HRH2 and gastric cancer risk
Tomiyasu Arisawa, Tomomitsu Tahara, Kazuaki Ozaki, Yasuhiro Matsue, Takahiro Minato, Hideto Yamada, Tomoe Nomura, Ranji Hayashi, Kazuhiro Matsunaga, Atsushi Fukumura, Masakatsu Nakamura, Nobuyuki Toshikuni, Hisakazu Shiroeda, Tomoyuki Shibata
Pages: 497-503 Published online on: 17 May 2012
Article
Diaminobenzene schiff base, a novel class of DNA minor groove binder
Muath H. Helal, Zena A. Al-Mudaris, Mohammed H. Al-Douh, Hasnah Osman, Habibah A. Wahab, Belal O. AlNajjar, Hassan H. Abdallah, Amin M.S. Abdul Majid
Pages: 504-510 Published online on: 18 May 2012
Article
Association of stem cell marker expression pattern and survival in human biliary tract cancer
Ralf Kemmerling, Beate Alinger, Otto Dietze, Hans-Christian Bösmüller, Matthias Ocker, Gernot W. Wolkersdörfer, Frieder Berr, Daniel Neureiter, Tobias Kiesslich
Pages: 511-522 Published online on: 14 May 2012
Article
Orlistat, a novel potent antitumor agent for ovarian cancer: proteomic analysis of ovarian cancer cells treated with Orlistat
Hui-Qiong Huang, Jing Tang, Sheng-Tao Zhou, Tao Yi, Hong-Ling Peng, Guo-Bo Shen, Na Xie, Kai Huang, Tao Yang, Jin-Hua Wu, Can-Hua Huang, Yu-Quan Wei, Xia Zhao
Pages: 523-532 Published online on: 08 May 2012
Article
ZGDHu-1 promotes apoptosis of chronic lymphocytic leukemia cells
Lian-Nv Qiu, Yong-Lie Zhou, Zhen-Ni Wang, Qiang Huang, Wei-Xiao Hu
Pages: 533-540 Published online on: 08 May 2012
Article
Fibroblast activation protein regulates tumor-associated fibroblasts and epithelial ovarian cancer cells
Dongmei Lai, Li Ma, Fangyuan Wang
Pages: 541-550 Published online on: 14 May 2012
Article
Inhibition of the mTOR/S6K signal is necessary to enhance fluorouracil-induced apoptosis in gastric cancer cells with HER2 amplification
Hideo Tomioka, Toru Mukohara, Yu Kataoka, Roudy Chiminch Ekyalongo, Yohei Funakoshi, Yasuo Imai, Naomi Kiyota, Yutaka Fujiwara, Hironobu Minami
Pages: 551-558 Published online on: 17 May 2012
Article
REIC/Dkk-3-encoding adenoviral vector as a potentially effective therapeutic agent for bladder cancer
Takeshi Hirata, Masami Watanabe, Haruki Kaku, Yasuyuki Kobayashi, Hiroshi Yamada, Masakiyo Sakaguchi, Kohji Takei, Nam-Ho Huh, Yasutomo Nasu, Hiromi Kumon
Pages: 559-564 Published online on: 31 May 2012
Article
The enhancement of tumor radioresponse by combined treatment with cepharanthine is accompanied by the inhibition of DNA damage repair and the induction of apoptosis in oral squamous cell carcinoma
Toyoko Harada, Koji Harada, Yoshiya Ueyama
Pages: 565-572 Published online on: 31 May 2012
Article
Angiotensin II enhances epithelial-to-mesenchymal transition through the interaction between activated hepatic stellate cells and the stromal cell-derived factor-1/CXCR4 axis in intrahepatic cholangiocarcinoma
Koichi Okamoto, Hidehiro Tajima, Shinichi Nakanuma, Seisho Sakai, Isamu Makino, Jun Kinoshita, Hironori Hayashi, Keishi Nakamura, Katsunobu Oyama, Hisatoshi Nakagawara, Hideto Fujita, Hiroyuki Takamura, Itasu Ninomiya, Hirohisa Kitagawa, Sachio Fushida, Takashi Fujimura, Shinichi Harada, Tomohiko Wakayama, Shoichi Iseki, Tetsuo Ohta
Pages: 573-582 Published online on: 29 May 2012
Article
Differential response to EGFR- and VEGF-targeted therapies in patient-derived tumor tissue xenograft models of colon carcinoma and related metastases
Ketao Jin, Huanrong Lan, Feilin Cao, Na Han, Zhenzhen Xu, Guangliang Li, Kuifeng He, Lisong Teng
Pages: 583-588 Published online on: 10 May 2012
Article
N-acetylglucosaminyltransferase V negatively regulates integrin α5β1-mediated monocyte adhesion and transmigration through vascular endothelium
Huo-Mei Yang, Chao Yu, Zhu Yang
Pages: 589-598 Published online on: 17 May 2012
Article
uPAR and cathepsin B knockdown inhibits radiation-induced PKC integrated integrin signaling to the cytoskeleton of glioma-initiating cells
Kiranmai Alapati, Sreelatha Gopinath, Rama Rao Malla, Venkata Ramesh Dasari, Jasti S. Rao
Pages: 599-610 Published online on: 24 May 2012
Article
Promoter methylation of RASSF1A modulates the effect of the microtubule-targeting agent docetaxel in breast cancer
Eun Young Gil, Uk Hyun Jo, Hoiseon Jeong, Young Mi Whang, Ok Hee Woo, Kyu Ran Cho, Jae Hong Seo, Aeree Kim, Eun Sook Lee, Insong Koh, Yeul Hong Kim, Kyong Hwa Park
Pages: 611-620 Published online on: 10 May 2012
Article
Generation and characterization of bioluminescent xenograft mouse models of MLL-related acute leukemias and in vivo evaluation of luciferase-targeting siRNA nanoparticles
Raffaella Fazzina, Lorenza Lombardini, Laura Mezzanotte, Aldo Roda, Patrizia Hrelia, Andrea Pession, Roberto Tonelli
Pages: 621-628 Published online on: 31 May 2012
Article
Screening of significantly hypermethylated genes in breast cancer using microarray-based methylated-CpG island recovery assay and identification of their expression levels
Zhen-Qiang Lian, Qi Wang, Wen-Ping Li, An-Qin Zhang, Ling Wu
Pages: 629-638 Published online on: 08 May 2012
Article
Development and characterization of a preclinical ovarian carcinoma model to investigate the mechanism of acquired resistance to trastuzumab
Leopoldo L. Luistro, James A. Rosinski, Hongjin Bian, Subal Bishayee, Pranela Rameshwar, Nicholas M. Ponzio, Steve R. Ritland
Pages: 639-651 Published online on: 08 May 2012
Article
Co-silencing of Birc5 (survivin) and Hspa5 (Grp78) induces apoptosis in hepatoma cells more efficiently than single gene interference
Qiang Wang, Rong Shu, Huijun He, Li Wang, Yuan Ma, Huifen Zhu, Zhihua Wang, Shuo Wang, Guanxin Shen, Ping Lei
Pages: 652-660 Published online on: 10 May 2012
Article
An IL-12/Shh-C domain fusion protein-based IL-12 autocrine loop for sustained natural killer cell activation
Lining Zhu, Zhihui Zhao, Yanzhang Wei, William Marcotte , Thomas E. Wagner, Xianzhong Yu
Pages: 661-669 Published online on: 08 May 2012
Article
Breast cancer proteomics reveals a positive correlation between glyoxalase 1 expression and high tumor grade
Miguel A. Fonseca-Sánchez, Sergio Rodríguez Cuevas, Guillermo Mendoza-Hernández, Veronica Bautista-Piña, Elena Arechaga Ocampo, Alfredo Hidalgo Miranda, Valeria Quintanar Jurado, Laurence A. Marchat, Elizbeth Álvarez-Sánchez, Carlos Pérez Plasencia, César López-Camarillo
Pages: 670-680 Published online on: 14 May 2012
Article
Reelin signalling in neuroblastoma: Migratory switch in metastatic stages
Jürgen Becker, Johanna Fröhlich, Christina Perske, Helena Pavlakovic, Jörg Wilting
Pages: 681-689 Published online on: 18 May 2012
Article
Transcriptional silencing of the inhibin-α gene in human gastric carcinoma cells
Young Il Kim, Jaejun Shim, Byung-Ho Kim, Sung Jae Lee, Ha Kyu Lee, Chunghee Cho, Byung-Nam Cho
Pages: 690-700 Published online on: 10 May 2012
Article
Characterization of sarcoma-like cells derived from endarterectomized tissues from patients with CTEPH and establishment of a mouse model of pulmonary artery intimal sarcoma
Takayuki Jujo, Seiichiro Sakao, Masashi Kantake, Miki Maruoka, Nobuhiro Tanabe, Yasunori Kasahara, Katsushi Kurosu, Masahisa Masuda, Kenichi Harigaya, Koichiro Tatsumi
Pages: 701-711 Published online on: 22 May 2012
Article
Combination of the ERK inhibitor AZD6244 and low-dose sorafenib in a xenograft model of human renal cell carcinoma
John Shyi Peng Yuen, Mei Yi Sim, Hong Gee Sim, Tsung Wen Chong, Weber Kam On Lau, Christopher Wai Sam Cheng, Richard Weijie Ong, Hung Huynh
Pages: 712-720 Published online on: 23 May 2012
Article
Loss of post-transcriptional regulation of DNMT3b by microRNAs: A possible molecular mechanism for the hypermethylation defect observed in a subset of breast cancer cell lines
Rupninder Sandhu, Ashley G. Rivenbark, William B. Coleman
Pages: 721-732 Published online on: 31 May 2012
Article
Association of amphiregulin with the cetuximab sensitivity of gastric cancer cell lines
Julia Kneissl, Simone Keller, Thomas Lorber, Stefan Heindl, Gisela Keller, Ingo Drexler, Alexander Hapfelmeier, Heinz Höfler, Birgit Luber
Pages: 733-744 Published online on: 14 May 2012
Article
A novel role for insulin resistance in the connection between obesity and postmenopausal breast cancer
Michael Weichhaus, John Broom, Klaus Wahle, Giovanna Bermano
Pages: 745-752 Published online on: 16 May 2012
Article
Combined administration of EGCG and IL-1 receptor antagonist efficiently downregulates IL-1-induced tumorigenic factors in U-2 OS human osteosarcoma cells
Anne-Sophie Hönicke, Stephan Albrecht Ender, Jürgen Radons
Pages: 753-758 Published online on: 28 May 2012
Article
Interleukin 11 regulates endometrial cancer cell adhesion and migration via STAT3
Virginia Lay, Joanne Yap, Stefan Sonderegger, Evdokia Dimitriadis
Pages: 759-764 Published online on: 18 May 2012
Article
A tumor-derived population (SCCOHT-1) as cellular model for a small cell ovarian carcinoma of the hypercalcemic type
Anna Otte, Gudrun Göhring, Doris Steinemann, Brigitte Schlegelberger, Stephanie Groos, Florian Länger, Hans-Heinrich Kreipe, Axel Schambach, Thomas Neumann, Peter Hillemanns, Tjoung-Won Park-Simon, Ralf Hass
Pages: 765-775 Published online on: 08 May 2012
Article