Journal Articles

Review

Cannabinoid-associated cell death mechanisms in tumor models (Review)

Giuseppe Calvaruso, Ornella Pellerito, Antonietta Notaro, Michela Giuliano

Pages: 407-413 Published online on: 14 May 2012
Article

Barrett's esophagus and esophageal cancer: An overview

Vincenza Conteduca, Domenico Sansonno, Giuseppe Ingravallo, Stefania Marangi, Sabino Russi, Gianfranco Lauletta, Franco Dammacco

Pages: 414-424 Published online on: 17 May 2012
Article Open Access

Synergistic activity of the mTOR inhibitor ridaforolimus and the antiandrogen bicalutamide in prostate cancer models

Rachel M. Squillace, David Miller, Scott D. Wardwell, Frank Wang, Tim Clackson, Victor M. Rivera

Pages: 425-432 Published online on: 18 May 2012
Article Open Access

Endothelial protein C receptor expressed by ovarian cancer cells as a possible biomarker of cancer onset

Elodie Ducros, Shahsoltan Mirshahi, Dalel Azzazene, Sophie Camilleri-Broët, Eliane Mery, Halema Al Farsi, Hamda Althawadi, Samaher Besbess, Jean Chidiac, Eric Pujade-Lauraine, Amu Therwath, Jeannette Soria, Massoud Mirshahi

Pages: 433-440 Published online on: 18 May 2012
Article Open Access

Expression and role of nestin in human cervical intraepithelial neoplasia and cervical cancer

Atsuki Sato, Toshiyuki Ishiwata, Yoko Matsuda, Tetsushi Yamamoto, Hirobumi Asakura, Toshiyuki Takeshita, Zenya Naito

Pages: 441-448 Published online on: 10 May 2012
Article Open Access

Antitumor activity of MEK and PI3K inhibitors against malignant pleural mesothelioma cells in vitro and in vivo

Seigo Miyoshi, Hironobu Hamada, Naohiko Hamaguchi, Aki Kato, Hitoshi Katayama, Kazunori Irifune, Ryoji Ito, Tatsuhiko Miyazaki, Takafumi Okura, Jitsuo Higaki

Pages: 449-456 Published online on: 08 May 2012
Article Open Access

The role of hepatic stellate cells in the regulation of T-cell function and the promotion of hepatocellular carcinoma

Wenxiu Zhao, Weixue Su, Penghao Kuang, Lei  Zhang, Jianming  Liu, Zhenyu Yin, Xiaomin  Wang

Pages: 457-464 Published online on: 24 May 2012
Article Open Access

Depolarization potentiates TRAIL-induced apoptosis in human melanoma cells: Role for ATP-sensitive K+ channels and endoplasmic reticulum stress

Yoshihiro Suzuki, Toshio Inoue, Mayumi Murai, Miki  Suzuki‑Karasaki, Toyoko Ochiai, Chisei  Ra

Pages: 465-475 Published online on: 17 May 2012
Article Open Access

The role of human peritoneal mesothelial cells in the fibrosis and progression of gastric cancer

Tomoya Tsukada, Sachio Fushida, Shinichi Harada, Yasumichi  Yagi, Jun  Kinoshita, Katsunobu Oyama, Hidehiro Tajima, Hideto  Fujita, Itasu Ninomiya, Takashi Fujimura, Tetsuo Ohta

Pages: 476-482 Published online on: 18 May 2012
Article

The clinical impact of breast scintigraphy acquired with a breast specific γ-camera (BSGC) in the diagnosis of breast cancer: Incremental value versus mammography

Angela Spanu, Daniela Sanna, Francesca Chessa, Alessandra Manca, Pierina Cottu, Alessandro Fancellu, Susanna Nuvoli, Giuseppe Madeddu

Pages: 483-489 Published online on: 24 May 2012
Article

Genome-wide screening for methylation-silenced genes in colorectal cancer

Ahmed Khamas, Toshiaki Ishikawa, Kaoru Mogushi, Satoru Iida, Megumi Ishiguro, Hiroshi Tanaka, Hiroyuki Uetake, Kenichi Sugihara

Pages: 490-496 Published online on: 30 May 2012
Article

Association between common genetic variant of HRH2 and gastric cancer risk

Tomiyasu Arisawa, Tomomitsu Tahara, Kazuaki Ozaki, Yasuhiro Matsue, Takahiro Minato, Hideto Yamada, Tomoe Nomura, Ranji Hayashi, Kazuhiro Matsunaga, Atsushi Fukumura, Masakatsu Nakamura, Nobuyuki Toshikuni, Hisakazu Shiroeda, Tomoyuki Shibata

Pages: 497-503 Published online on: 17 May 2012
Article

Diaminobenzene schiff base, a novel class of DNA minor groove binder

Muath H. Helal, Zena A. Al-Mudaris, Mohammed H. Al-Douh, Hasnah Osman, Habibah A. Wahab, Belal O. AlNajjar, Hassan H. Abdallah, Amin M.S. Abdul Majid

Pages: 504-510 Published online on: 18 May 2012
Article

Association of stem cell marker expression pattern and survival in human biliary tract cancer

Ralf Kemmerling, Beate Alinger, Otto Dietze, Hans-Christian Bösmüller, Matthias Ocker, Gernot W. Wolkersdörfer, Frieder Berr, Daniel Neureiter, Tobias Kiesslich

Pages: 511-522 Published online on: 14 May 2012
Article

Orlistat, a novel potent antitumor agent for ovarian cancer: proteomic analysis of ovarian cancer cells treated with Orlistat

Hui-Qiong Huang, Jing Tang, Sheng-Tao Zhou, Tao Yi, Hong-Ling Peng, Guo-Bo  Shen, Na Xie, Kai Huang, Tao Yang, Jin-Hua Wu, Can-Hua Huang, Yu-Quan Wei, Xia  Zhao

Pages: 523-532 Published online on: 08 May 2012
Article

ZGDHu-1 promotes apoptosis of chronic lymphocytic leukemia cells

Lian-Nv Qiu, Yong-Lie Zhou, Zhen-Ni Wang, Qiang Huang, Wei-Xiao Hu

Pages: 533-540 Published online on: 08 May 2012
Article

Fibroblast activation protein regulates tumor-associated fibroblasts and epithelial ovarian cancer cells

Dongmei Lai, Li Ma, Fangyuan Wang

Pages: 541-550 Published online on: 14 May 2012
Article

Inhibition of the mTOR/S6K signal is necessary to enhance fluorouracil-induced apoptosis in gastric cancer cells with HER2 amplification

Hideo Tomioka, Toru Mukohara, Yu Kataoka, Roudy Chiminch Ekyalongo, Yohei  Funakoshi, Yasuo Imai, Naomi Kiyota, Yutaka Fujiwara, Hironobu Minami

Pages: 551-558 Published online on: 17 May 2012
Article

REIC/Dkk-3-encoding adenoviral vector as a potentially effective therapeutic agent for bladder cancer

Takeshi Hirata, Masami Watanabe, Haruki Kaku, Yasuyuki Kobayashi, Hiroshi Yamada, Masakiyo Sakaguchi, Kohji Takei, Nam-Ho Huh, Yasutomo Nasu, Hiromi Kumon

Pages: 559-564 Published online on: 31 May 2012
Article

Angiotensin II enhances epithelial-to-mesenchymal transition through the interaction between activated hepatic stellate cells and the stromal cell-derived factor-1/CXCR4 axis in intrahepatic cholangiocarcinoma

Koichi Okamoto, Hidehiro Tajima, Shinichi Nakanuma, Seisho Sakai, Isamu Makino, Jun Kinoshita, Hironori Hayashi, Keishi Nakamura, Katsunobu Oyama, Hisatoshi Nakagawara, Hideto Fujita, Hiroyuki Takamura, Itasu Ninomiya, Hirohisa Kitagawa, Sachio Fushida, Takashi Fujimura, Shinichi Harada, Tomohiko Wakayama, Shoichi Iseki, Tetsuo Ohta

Pages: 573-582 Published online on: 29 May 2012
Article

Differential response to EGFR- and VEGF-targeted therapies in patient-derived tumor tissue xenograft models of colon carcinoma and related metastases

Ketao Jin, Huanrong Lan, Feilin Cao, Na Han, Zhenzhen  Xu, Guangliang Li, Kuifeng He, Lisong Teng

Pages: 583-588 Published online on: 10 May 2012
Article

uPAR and cathepsin B knockdown inhibits radiation-induced PKC integrated integrin signaling to the cytoskeleton of glioma-initiating cells

Kiranmai Alapati, Sreelatha Gopinath, Rama Rao Malla, Venkata Ramesh Dasari, Jasti S. Rao

Pages: 599-610 Published online on: 24 May 2012
Article

Promoter methylation of RASSF1A modulates the effect of the microtubule-targeting agent docetaxel in breast cancer

Eun Young Gil, Uk Hyun Jo, Hoiseon Jeong, Young Mi Whang, Ok Hee Woo, Kyu Ran Cho, Jae Hong Seo, Aeree Kim, Eun Sook Lee, Insong Koh, Yeul Hong Kim, Kyong Hwa Park

Pages: 611-620 Published online on: 10 May 2012
Article

Generation and characterization of bioluminescent xenograft mouse models of MLL-related acute leukemias and in vivo evaluation of luciferase-targeting siRNA nanoparticles

Raffaella Fazzina, Lorenza Lombardini, Laura  Mezzanotte, Aldo  Roda, Patrizia Hrelia, Andrea Pession, Roberto  Tonelli

Pages: 621-628 Published online on: 31 May 2012
Article
Article

Development and characterization of a preclinical ovarian carcinoma model to investigate the mechanism of acquired resistance to trastuzumab

Leopoldo L. Luistro, James A. Rosinski, Hongjin Bian, Subal Bishayee, Pranela Rameshwar, Nicholas M. Ponzio, Steve R. Ritland

Pages: 639-651 Published online on: 08 May 2012
Article

Co-silencing of Birc5 (survivin) and Hspa5 (Grp78) induces apoptosis in hepatoma cells more efficiently than single gene interference

Qiang Wang, Rong Shu, Huijun He, Li Wang, Yuan Ma, Huifen Zhu, Zhihua Wang, Shuo Wang, Guanxin Shen, Ping Lei

Pages: 652-660 Published online on: 10 May 2012
Article

An IL-12/Shh-C domain fusion protein-based IL-12 autocrine loop for sustained natural killer cell activation

Lining Zhu, Zhihui Zhao, Yanzhang Wei, William Marcotte , Thomas E. Wagner, Xianzhong Yu

Pages: 661-669 Published online on: 08 May 2012
Article

Breast cancer proteomics reveals a positive correlation between glyoxalase 1 expression and high tumor grade

Miguel A. Fonseca-Sánchez, Sergio Rodríguez Cuevas, Guillermo Mendoza-Hernández, Veronica Bautista-Piña, Elena Arechaga Ocampo, Alfredo Hidalgo Miranda, Valeria Quintanar Jurado, Laurence A. Marchat, Elizbeth Álvarez-Sánchez, Carlos Pérez Plasencia, César López-Camarillo

Pages: 670-680 Published online on: 14 May 2012
Article

Reelin signalling in neuroblastoma: Migratory switch in metastatic stages

Jürgen Becker, Johanna Fröhlich, Christina Perske, Helena Pavlakovic, Jörg Wilting

Pages: 681-689 Published online on: 18 May 2012
Article

Transcriptional silencing of the inhibin-α gene in human gastric carcinoma cells

Young Il Kim, Jaejun Shim, Byung-Ho Kim, Sung Jae Lee, Ha Kyu Lee, Chunghee Cho, Byung-Nam Cho

Pages: 690-700 Published online on: 10 May 2012
Article

Characterization of sarcoma-like cells derived from endarterectomized tissues from patients with CTEPH and establishment of a mouse model of pulmonary artery intimal sarcoma

Takayuki Jujo, Seiichiro Sakao, Masashi Kantake, Miki Maruoka, Nobuhiro Tanabe, Yasunori Kasahara, Katsushi Kurosu, Masahisa Masuda, Kenichi Harigaya, Koichiro Tatsumi

Pages: 701-711 Published online on: 22 May 2012
Article

Combination of the ERK inhibitor AZD6244 and low-dose sorafenib in a xenograft model of human renal cell carcinoma

John Shyi Peng Yuen, Mei Yi Sim, Hong Gee Sim, Tsung Wen Chong, Weber  Kam On Lau, Christopher  Wai Sam Cheng, Richard Weijie Ong, Hung  Huynh

Pages: 712-720 Published online on: 23 May 2012
Article

Association of amphiregulin with the cetuximab sensitivity of gastric cancer cell lines

Julia Kneissl, Simone Keller, Thomas Lorber, Stefan Heindl, Gisela Keller, Ingo Drexler, Alexander Hapfelmeier, Heinz Höfler, Birgit Luber

Pages: 733-744 Published online on: 14 May 2012
Article

A novel role for insulin resistance in the connection between obesity and postmenopausal breast cancer

Michael Weichhaus, John Broom, Klaus Wahle, Giovanna Bermano

Pages: 745-752 Published online on: 16 May 2012
Article

Combined administration of EGCG and IL-1 receptor antagonist efficiently downregulates IL-1-induced tumorigenic factors in U-2 OS human osteosarcoma cells

Anne-Sophie Hönicke, Stephan Albrecht Ender, Jürgen Radons

Pages: 753-758 Published online on: 28 May 2012
Article

Interleukin 11 regulates endometrial cancer cell adhesion and migration via STAT3

Virginia Lay, Joanne Yap, Stefan Sonderegger, Evdokia Dimitriadis

Pages: 759-764 Published online on: 18 May 2012
Article

A tumor-derived population (SCCOHT-1) as cellular model for a small cell ovarian carcinoma of the hypercalcemic type

Anna Otte, Gudrun Göhring, Doris Steinemann, Brigitte Schlegelberger, Stephanie Groos, Florian Länger, Hans-Heinrich Kreipe, Axel Schambach, Thomas Neumann, Peter Hillemanns, Tjoung-Won Park-Simon, Ralf Hass

Pages: 765-775 Published online on: 08 May 2012
Article

Casein kinase 2 inhibition modulates the DNA damage response but fails to radiosensitize malignant glioma cells

Jérôme Kroonen, Maria Artesi, Valérie Capraro, Minh-Tuan Nguyen-Khac, Marie Willems, Arnab Chakravarti, Vincent Bours, Pierre A. Robe

Pages: 776-782 Published online on: 18 May 2012
Journal Cover

Cover Legend PDF

August 2012
Volume 41 Issue 2

Print ISSN: 1019-6439
Online ISSN: 1791-2423

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