Journal Articles
Review
Nanoparticle strategies for cancer therapeutics: Nucleic acids, polyamines, bovine serum amine oxidase and iron oxide nanoparticles (Review)
Enzo Agostinelli, Fabio Vianello, Giuseppe Magliulo, Thresia Thomas, T. J. Thomas
Pages: 5-16 Published online on: 14 October 2014
Review
The fusion of two worlds: Non-coding RNAs and extracellular vesicles - diagnostic and therapeutic implications (Review)
Yukie Sato-Kuwabara, Sonia A. Melo, Fernando A. Soares, George A. Calin
Pages: 17-27 Published online on: 17 October 2014
Article
Programmed death-1 blockade enhances the antitumor effects of peptide vaccine-induced peptide-specific cytotoxic T lymphocytes
Yu Sawada, Toshiaki Yoshikawa, Manami Shimomura, Tatsuaki Iwama, Itaru Endo, Tetsuya Nakatsura
Pages: 28-36 Published online on: 30 October 2014
Article
Conditioned media from human macrophages of M1 phenotype attenuate the cytotoxic effect of 5‑fluorouracil on the HT‑29 colon cancer cell line
Alexander Hedbrant, Ann Erlandsson, Dick Delbro, Jonny Wijkander
Pages: 37-46 Published online on: 07 October 2014
Article
Hsp90 inhibitor induces autophagy and apoptosis in osteosarcoma cells
Masaki Mori, Toshiaki Hitora, Osamu Nakamura, Yoshiki Yamagami, Ryosuke Horie, Hideki Nishimura, Tetsuji Yamamoto
Pages: 47-54 Published online on: 23 October 2014
Article
Feasibility study of personalized peptide vaccination for advanced non-small cell lung cancer patients who failed two or more treatment regimens
Teppei Yamada, Yasuhiro Terazaki, Shinjiro Sakamoto, Koichi Yoshiyama, Satoko Matsueda, Nobukazu Komatsu, Kayoko Waki, Akira Yamada, Akihiko Kawahara, Masayoshi Kage, Shunichi Sugawara, Yuichi Yamashita, Tetsuro Sasada, Shinzo Takamori, Kyogo Itoh
Pages: 55-62 Published online on: 07 October 2014
Article
5-FU resistance abrogates the amplified cytotoxic effects induced by inhibiting checkpoint kinase 1 in p53-mutated colon cancer cells
Tomofumi Akasaka, Masahiko Tsujii, Jumpei Kondo, Yoshito Hayashi, Jin Ying, Yuquan Lu, Motohiko Kato, Takuya Yamada, Shunsuke Yamamoto, Takuya Inoue, Yoshiki Tsujii, Akira Maekawa, Tetsuji Fujinaga, Eri Shiraishi, Satoshi Hiyama, Takahiro Inoue, Shinichiro Shinzaki, Kenji Watabe, Tsutomu Nishida, Hideki Iijima, Tetsuo Takehara
Pages: 63-70 Published online on: 06 October 2014
Article
Strong T‑cell costimulation can reactivate tumor antigen‑specific T cells in late‑stage metastasized colorectal carcinoma patients: Results from a phase Ⅰ clinical study
Volker Schirrmacher, Christoph Schlude, Jürgen Weitz, Philipp Beckhove
Pages: 71-77 Published online on: 06 October 2014
Article
Pancreatic cancer immunotherapy using a tumor lysate vaccine, engineered to express α-gal epitopes, targets pancreatic cancer stem cells
Tsukasa Tanida, Masahiro Tanemura, Eiji Miyoshi, Hiroaki Nagano, Kenta Furukawa, Yuji Nonaka, Hirofumi Akita, Naoki Hama, Hiroshi Wada, Koichi Kawamoto, Shogo Kobayashi, Hidetoshi Eguchi, Masaki Mori, Yuichiro Doki
Pages: 78-90 Published online on: 21 October 2014
Article
Transformation of NIH3T3 mouse fibroblast cells by MUC16 mucin (CA125) is driven by its cytoplasmic tail
Panagiota Giannakouros, Isabelle Matte, Claudine Rancourt, Alain Piché
Pages: 91-98 Published online on: 14 October 2014
Article
Autoacetylation regulates differentially the roles of ARD1 variants in tumorigenesis
Ji Hae Seo, Ji-Hyeon Park, Eun Ji Lee, Tam Thuy Lu Vo, Hoon Choi, Jae Kyung Jang, Hee-Jun Wee, Bum Ju Ahn, Jong-Ho Cha, Min Wook Shin, Kyu-Won Kim
Pages: 99-106 Published online on: 17 October 2014
Article
Expression pattern of the PRDX2, RAB1A, RAB1B, RAB5A and RAB25 genes in normal and cancer cervical tissues
Andrej Nikoshkov, Kristina Broliden, Sanaz Attarha, Vitali Sviatoha, Ann‑Cathrin Hellström, Miriam Mints, Sonia Andersson
Pages: 107-112 Published online on: 23 October 2014
Article
Downregulation of thymidylate synthase and E2F1 by arsenic trioxide in mesothelioma
Sze-Kwan Lam, Yuan-Yuan Li, Chun-Yan Zheng, James Chung-Man Ho
Pages: 113-122 Published online on: 21 October 2014
Article
Prognostic significance of SOX18 expression in non-small cell lung cancer
Aleksandra Jethon, Bartosz Pula, Mateusz Olbromski, Bozena Werynska, Beata Muszczynska-Bernhard, Wojciech Witkiewicz, Piotr Dziegiel, Marzena Podhorska-Okolow
Pages: 123-132 Published online on: 07 October 2014
Article
+TIP EB1 downregulates paclitaxel‑induced proliferation inhibition and apoptosis in breast cancer cells through inhibition of paclitaxel binding on microtubules
Geethu Emily Thomas, Jamuna S. Sreeja, K. K. Gireesh, Hindol Gupta, Tapas K. Manna
Pages: 133-146 Published online on: 07 October 2014
Article
Potent tumor tropism of induced pluripotent stem cells and induced pluripotent stem cell-derived neural stem cells in the mouse intracerebral glioma model
Tomohiro Yamazoe, Shinichiro Koizumi, Tomohiro Yamasaki, Shinji Amano, Tsutomu Tokuyama, Hiroki Namba
Pages: 147-152 Published online on: 08 October 2014
Article
Mutation of β-catenin in a radiation and estrogen breast cancer model
Debasish Roy, Gloria M. Calaf
Pages: 153-160 Published online on: 22 October 2014
Article
MicroRNA-93 regulates cyclin G2 expression and plays an oncogenic role in laryngeal squamous cell carcinoma
Xiyan Xiao, Liang Zhou, Pengyu Cao, Hongli Gong, Yanping Zhang
Pages: 161-174 Published online on: 10 October 2014
Article
Prognostic significance and therapeutic implications of peroxisome proliferator-activated receptor γ overexpression in human pancreatic carcinoma
Yan Zhang, Hui-Yan Luo, Guang-Lin Liu, De-Shen Wang, Zhi-Qiang Wang, Zhao-Lei Zeng, Rui-Hua Xu
Pages: 175-184 Published online on: 17 October 2014
Article
Silencing of galectin-3 represses osteosarcoma cell migration and invasion through inhibition of FAK/Src/Lyn activation and β-catenin expression and increases susceptibility to chemotherapeutic agents
Ga Bin Park, Dae-Jin Kim, Yeong-Seok Kim, Hyun-Kyung Lee, Chang Wan Kim, Dae Young Hur
Pages: 185-194 Published online on: 22 October 2014
Article
The Pleckstrin and Sec7 domain-containing gene as a novel epigenetic modification marker in human gastric cancer and its clinical significance Corrigendum in /10.3892/ijo.2022.5313
Xinjiang Zhu, Jian Liu, Xiaoyang Xu, Chundong Zhang, Dongqiu Dai
Pages: 195-204 Published online on: 30 October 2014
Article
Eps8 regulates cellular proliferation and migration of breast cancer
Cheng Chen, Zhongheng Liang, Wenhuan Huang, Xinxin Li, Fangliang Zhou, Xiang Hu, Mei Han, Xiaofeng Ding, Shuanglin Xiang
Pages: 205-214 Published online on: 17 October 2014
Article
HIF-1α decoy oligodeoxynucleotides inhibit HIF-1α signaling and breast cancer proliferation
Xuhong Zhu, Qin Li, Shuang Li, Bote Chen, Haidong Zou
Pages: 215-222 Published online on: 21 October 2014
Article
PJ34, a poly(ADP-ribose) polymerase (PARP) inhibitor, reverses melphalan-resistance and inhibits repair of DNA double-strand breaks by targeting the FA/BRCA pathway in multidrug resistant multiple myeloma cell line RPMI8226/R
Ting Xiong, Heng Wei, Xiaoqiong Chen, Hui Xiao
Pages: 223-232 Published online on: 23 October 2014
Article
HIF2α is associated with poor prognosis and affects the expression levels of survivin and cyclin D1 in gastric carcinoma
Wei-Wei Tong, Guang-Hui Tong, Xie-Xiao Chen, Hua-Chuan Zheng, Yin-Zhao Wang
Pages: 233-242 Published online on: 22 October 2014
Article
Oxime bond-linked daunorubicin-GnRH-III bioconjugates exert antitumor activity in castration-resistant prostate cancer cells via the type I GnRH receptor
Marina Montagnani Marelli, Marilena Manea, Roberta M. Moretti, Monica Marzagalli, Patrizia Limonta
Pages: 243-253 Published online on: 24 October 2014
Article
TIPE2 inhibits TNF-α-induced hepatocellular carcinoma cell metastasis via Erk1/2 downregulation and NF-κB activation
Yue Hua Zhang, Hong Qiong Yan, Fang Wang, Yan Yan Wang, Yi Na Jiang, Yi Nan Wang, Feng Guang Gao
Pages: 254-264 Published online on: 23 October 2014
Article
Esculetin (6,7-dihydroxycoumarin): A potential cancer chemopreventive agent through suppression of Sp1 in oral squamous cancer cells
Jin Hyoung Cho, Jae-Cheon Shin, Jung-Jae Cho, Yung Hyun Choi, Jung-Hyun Shim, Jung-Il Chae
Pages: 265-271 Published online on: 07 October 2014
Article
Alteration of epithelial-mesenchymal transition markers in human normal ovaries and neoplastic ovarian cancers
Bo-Rim Yi, Tae-Hee Kim, Ye-Seul Kim, Kyung-Chul Choi
Pages: 272-280 Published online on: 07 October 2014
Article
Real-time quantitative RT-PCR detection of circulating tumor cells from breast cancer patients
Maowen Guo, Xiaotian Li, Shaohua Zhang, Hua Song, Wenhui Zhang, Xueyi Shang, Yuling Zheng, Hua Jiang, Qingyu Lv, Yongqiang Jiang, Huaijie Hao
Pages: 281-289 Published online on: 29 October 2014
Article
Upregulation of CRMP4, a new prostate cancer metastasis suppressor gene, inhibits tumor growth in a nude mouse intratibial injection model
Wei Zhou, Peigen Xie, Mao Pang, Bu Yang, Youqiang Fang, Tao Shu, Chang Liu, Xuan Wang, Liangming Zhang, Shangfu Li, Limin Rong
Pages: 290-298 Published online on: 10 October 2014
Article
Combination of SNX-2112 with 5-FU exhibits antagonistic effect in esophageal cancer cells
Yuting Liu, Xiao Wang, Ying Wang, Yi Zhang, Kai Zheng, Haizhao Yan, Li Zhang, Wenbo Chen, Xiaoyan Wang, Qiuying Liu, Shaoxiang Wang, Yifei Wang
Pages: 299-307 Published online on: 20 October 2014
Article
Selective anticancer effects and protection from chemotherapy by the botanical compound LCS101: Implications for cancer treatment
Zoya Cohen, Yair Maimon, Merav Yoeli-Lerner, Peiying Yang, Noah Samuels, Raanan Berger
Pages: 308-316 Published online on: 17 October 2014
Article
SOX2 promotes tumorigenicity and inhibits the differentiation of I-type neuroblastoma cells
Shaobo Yang, Jicui Zheng, Xianmin Xiao, Ting Xu, Weitao Tang, Haitao Zhu, Lin Yang, Shan Zheng, Kuiran Dong, Guomin Zhou, Yang Wang
Pages: 317-323 Published online on: 17 October 2014
Article
The effect of organic anion-transporting polypeptides 1B1, 1B3 and 2B1 on the antitumor activity of flavopiridol in breast cancer cells
Stefan Brenner, Juliane Riha, Benedikt Giessrigl, Theresia Thalhammer, Michael Grusch, Georg Krupitza, Bruno Stieger, Walter Jäger
Pages: 324-332 Published online on: 24 October 2014
Article
Decreased expression of the SPOP gene is associated with poor prognosis in glioma
Dacheng Ding, Tao Song, Wu Jun, Zeming Tan, Jiasheng Fang
Pages: 333-341 Published online on: 24 October 2014
Article
A novel pyrido-thieno-pyrimidine derivative activates p53 through induction of phosphorylation and acetylation in colorectal cancer cells
Mi Ae Kang, Mi-Sook Kim, Ji Young Kim, Young-Joo Shin, Jie-Young Song, Jae-Hoon Jeong
Pages: 342-350 Published online on: 22 October 2014
Article
The key role of PML in IFN-α induced cellular senescence of human mesenchymal stromal cells
Shan Fu, Jieping Wei, Gang Wang, Binsheng Wang, Yebo Wang, Xiaoyu Lai, He Huang
Pages: 351-359 Published online on: 30 October 2014
Article
Tetrandrine induces G1/S cell cycle arrest through the ROS/Akt pathway in EOMA cells and inhibits angiogenesis in vivo
Wenkai Xiao, Yajie Jiang, Qiuxu Men, Ling Yuan, Zebo Huang, Ting Liu, Wenhua Li, Xin Liu
Pages: 360-368 Published online on: 29 October 2014
Article
Assessment of gene promoter G‑quadruplex binding and modulation by a naphthalene diimide derivative in tumor cells
Matteo Nadai, Graziella Cimino‑Reale, Giovanna Sattin, Filippo Doria, Elena Butovskaya, Nadia Zaffaroni, Mauro Freccero, Manlio Palumbo, Sara N. Richter, Marco Folini
Pages: 369-380 Published online on: 23 October 2014
Article
Long-term health-related quality of life after curative treatment for prostate cancer: A regional cross-sectional comparison of two standard treatment modalities
Marie Hjälm-Eriksson, Bo Lennernäs, Anders Ullén, Hemming Johansson, Jonas Hugosson, Sten Nilsson, Yvonne Brandberg
Pages: 381-388 Published online on: 29 October 2014
Article
The alkaloid emetine sensitizes ovarian carcinoma cells to cisplatin through downregulation of bcl-xL
Qi Sun, Shingo Yogosawa, Yosuke Iizumi, Toshiyuki Sakai, Yoshihiro Sowa
Pages: 389-394 Published online on: 08 October 2014
Article
Cks1 proteasomal turnover is a predominant mode of regulation in breast cancer cells: Role of key tyrosines and lysines
Vinayak Khattar, Jaideep V. Thottassery
Pages: 395-406 Published online on: 23 October 2014
Article
Circulating tumor cells before and during follow-up after breast cancer surgery
Guus van Dalum, Gert Jan van der Stam, Arjan G.J. Tibbe, Bas Franken, Walter J.B. Mastboom, Ivan Vermes, Marco R. de Groot, Leon W.M.M. Terstappen
Pages: 407-413 Published online on: 06 October 2014
Article
Geographical and anatomical influences on human papillomavirus prevalence diversity in head and neck squamous cell carcinoma in Germany
Elgar Susanne Quabius, Jochen Haag, André Kühnel, Hannes Henry, Anna Sophie Hoffmann, Tibor Görögh, Jürgen Hedderich, Matthias Evert, Achim G. Beule, Steffen Maune, Rainald Knecht, Attila Óvári, Martin Durisin, Florian Hoppe, Silke Tribius, Christoph Röcken, Petra Ambrosch, Markus Hoffmann
Pages: 414-422 Published online on: 07 October 2014
Article
Multiple roles of extracellular fibroblast growth factors in lung cancer cells
Takahiro Suzuki, Hiroyuki Yasuda, Koji Funaishi, Daisuke Arai, Kota Ishioka, Keiko Ohgino, Tetsuo Tani, Junko Hamamoto, Ayano Ohashi, Katsuhiko Naoki, Tomoko Betsuyaku, Kenzo Soejima
Pages: 423-429 Published online on: 21 October 2014
Article