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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December-2014 Volume 34 Issue 6

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

The kidney tight junction (Review)

Jianghui Hou
Pages: 1451-1457
Published online on: 01 October 2014

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Article Open Access

Dissecting the mechanism of carotid atherosclerosis from the perspective of regulation

Min Lin, Lin Zhao, Wenlong Zhao, Jing Weng
Pages: 1458-1466
Published online on: 09 October 2014

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Article Open Access

Identification of I411K, a novel missense EYA4 mutation causing autosomal dominant non‑syndromic hearing loss

Minxing Tan, Xiaofei Shen, Jun Yao, Qinjun Wei, Yajie Lu, Xin Cao, Guangqian Xing
Pages: 1467-1472
Published online on: 19 September 2014

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Article Open Access

Inhibition of Src phosphorylation reduces damage to the blood-brain barrier following transient focal cerebral ischemia in rats

Yongsheng Bai, Guanghui Xu, Mengxue Xu, Qi Li, Xinyue Qin
Pages: 1473-1482
Published online on: 24 September 2014

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Article Open Access

Adseverin knockdown inhibits osteoclastogenesis in RAW264.7 cells Retraction in /10.3892/ijmm.2014.1990

Wenting Qi, Yan Gao, Jun Tian, Hongwei Jiang
Pages: 1483-1491
Published online on: 22 September 2014

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Article Open Access

Xuebijing exerts protective effects on lung permeability leakage and lung injury by upregulating Toll-interacting protein expression in rats with sepsis

Ming-Wei Liu, Yun-Hui Wang, Chuan-Yun Qian, Hui Li
Pages: 1492-1504
Published online on: 23 September 2014

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Article Open Access

Zinc finger protein 382 is downregulated by promoter hypermethylation in pediatric acute myeloid leukemia patients

Yan-Fang Tao, Shao-Yan Hu, Jun Lu, Lan Cao, Wen-Li Zhao, Pei-Fang Xiao, Li-Xiao Xu, Zhi-Heng Li, Na-Na Wang, Xiao-Juan Du, Li-Chao Sun, He Zhao, Fang Fang, Guang-Hao Su, Yan-Hong Li, Yi-Ping Li, Yun-Yun Xu, Jian Ni, Jian Wang, Xing Feng, Jian Pan
Pages: 1505-1515
Published online on: 13 October 2014

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Article

Detoxifying effect of fermented black ginseng on H2O2-induced oxidative stress in HepG2 cells

Min-Ji Bak, Woo-Sik Jeong, Kyu-Bong Kim
Pages: 1516-1522
Published online on: 16 October 2014

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Article

Orexin-A stimulates 3β-hydroxysteroid dehydrogenase expression and cortisol production in H295R human adrenocortical cells through the AKT pathway

Xiaocen Chang, Yuyan Zhao, Shujing Ju, Lei Guo
Pages: 1523-1528
Published online on: 06 October 2014

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Article

Astragalus polysaccharides exert protective effects in newborn rats with bronchopulmonary dysplasia by upregulating the expression of EGFL7 in lung tissue

Xiao-Hong Wang, Wei-Min Huang
Pages: 1529-1536
Published online on: 30 September 2014

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Article

Poly-ε-caprolactone composite scaffolds for bone repair

R. Di Liddo, P. Paganin, S. Lora, D. Dalzoppo, C. Giraudo, D. Miotto, A.  Tasso, S.  Barbon, M.  Artico, E. Bianchi, P. P. Parnigotto, M. T. Conconi, C.  Grandi
Pages: 1537-1546
Published online on: 01 October 2014

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Article

Feasibility of lentiviral‑mediated sodium iodide symporter gene delivery for the efficient monitoring of bone marrow‑derived mesenchymal stem cell transplantation and survival

Shuo Shi, Min Zhang, Rui Guo, Ying Miao, Miao Zhang, Jiajia Hu, Yun Xi, Biao Li
Pages: 1547-1554
Published online on: 14 October 2014

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Article

ZnPP reduces autophagy and induces apoptosis, thus aggravating liver ischemia/reperfusion injury in vitro

Yun Wang, Xuanxuan Xiong, Hao Guo, Mingbo Wu, Xiangcheng Li, Yuanchao Hu, Guangwei Xie, Jian Shen, Qingzhong Tian
Pages: 1555-1564
Published online on: 14 October 2014

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Article

The downregulation of miR-144 is associated with the growth and invasion of osteosarcoma cells through the regulation of TAGLN expression

Mingdong Zhao, Jianshu Huang, Keke Gui, Min Xiong, Guoping Cai, Ji Xu, Kun Wang, Dechang Liu, Xinchao Zhang, Wangping Yin
Pages: 1565-1572
Published online on: 10 October 2014

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Article

Duhuo Jisheng decoction treatment inhibits the sodium nitroprussiate‑induced apoptosis of chondrocytes through the mitochondrial‑dependent signaling pathway

Fayuan Liu, Guozhong Liu, Wenna Liang, Hongzhi Ye, Xiaping Weng, Pingdong Lin, Huiting Li, Jiashou Chen, Xianxiang Liu, Xihai Li
Pages: 1573-1580
Published online on: 10 October 2014

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Article

NKX2-6 mutation predisposes to familial atrial fibrillation

Jun Wang, Dai-Fu Zhang, Yu-Min Sun, Ruo-Gu Li, Xing-Biao Qiu, Xin-Kai Qu, Xu Liu, Wei-Yi Fang, Yi-Qing Yang
Pages: 1581-1590
Published online on: 16 October 2014

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Article

The marine-derived fungal metabolite, terrein, inhibits cell proliferation and induces cell cycle arrest in human ovarian cancer cells

Yi-Fei Chen, Shu-Ying Wang, Hong Shen, Xiao-Fen Yao, Feng-Li Zhang, Dongmei Lai
Pages: 1591-1598
Published online on: 13 October 2014

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Article

miR‑96 functions as a tumor suppressor gene by targeting NUAK1 in pancreatic cancer

Xuan Huang, Wei Lv, Jian‑Hua Zhang, Da‑Lin Lu
Pages: 1599-1605
Published online on: 19 September 2014

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Article

Effects of ornithine decarboxylase antizyme 1 on the proliferation and differentiation of human oral cancer cells

Xing Wang, Li Jiang
Pages: 1606-1612
Published online on: 10 October 2014

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Article

Extract of the mycelium of T. matsutake inhibits elastase activity and TPA-induced MMP-1 expression in human fibroblasts

So Young Kim, Kyung Chan Go, Yi Seop Song, Yeon Su Jeong, Eun Joo Kim, Beom Joon Kim
Pages: 1613-1621
Published online on: 14 October 2014

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Article

Mutant hypoxia‑inducible factor 1α modified bone marrow mesenchymal stem cells ameliorate cerebral ischemia

Chunyu Yang, Hua Liu, Danping Liu
Pages: 1622-1628
Published online on: 30 September 2014

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Article

Amelioration of hypoxia and LPS‑induced intestinal epithelial barrier dysfunction by emodin through the suppression of the NF‑κB and HIF‑1α signaling pathways

Qi Lei, Fu Qiang, Du Chao, Wu Di, Zhang Guoqian, Yuan Bo, Yan Lina
Pages: 1629-1639
Published online on: 13 October 2014

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Article

Prednisone inhibits the IL-1β-induced expression of COX-2 in HEI-OC1 murine auditory cells through the inhibition of ERK-1/2, JNK-1 and AP-1 activity

Hua Hong, Byeong-Churl Jang
Pages: 1640-1646
Published online on: 14 October 2014

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Article

Obesity increases histone H3 lysine 9 and 18 acetylation at Tnfa and Ccl2 genes in mouse liver

Michal Mikula, Aneta Majewska, Joanna Karolina Ledwon, Artur Dzwonek, Jerzy Ostrowski
Pages: 1647-1654
Published online on: 03 October 2014

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Article

Knockdown of TRAF4 expression suppresses osteosarcoma cell growth in vitro and in vivo

Weitao Yao, Xin Wang, Qiqing Cai, Songtao Gao, Jiaqiang Wang, Peng Zhang
Pages: 1655-1660
Published online on: 29 September 2014

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Article

Tanshinone IIA inhibits human gastric carcinoma AGS cell growth by decreasing BiP, TCTP, Mcl‑1 and Bcl‑xL and increasing Bax and CHOP protein expression

Chin‑Cheng Su
Pages: 1661-1668
Published online on: 29 September 2014

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Article

Genistein inhibits pro‑inflammatory cytokines in human mast cell activation through the inhibition of the ERK pathway

Dong Hwan Kim, Woo‑Sung Jung, Mi Eun Kim, Hee‑Woo Lee, Hwa‑Young Youn, Jong Keun Seon, Haeng‑Nam Lee, Jun Sik Lee
Pages: 1669-1674
Published online on: 02 October 2014

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Article

Induction of apoptosis by obovatol as a novel therapeutic strategy for acute myeloid leukemia

Hyeng-Soo Kim, Ga Young Lim, Junmo Hwang, Zae Young Ryoo, Tae-Lin Huh, Sanggyu Lee
Pages: 1675-1680
Published online on: 02 October 2014

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Article

Evaluation and validation of the suitable control genes for quantitative PCR studies in plasma DNA for non‑invasive prenatal diagnosis

Qiwei Yang, Hassan Abdellah Ahmed Ali, Shan Yu, Lin  Zhang, Xiuying Li, Zhenwu Du, Guizhen Zhang
Pages: 1681-1687
Published online on: 23 September 2014

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Article

Identification of the responsible proteins for increased selenium bioavailability in the brain of transgenic rats overexpressing selenoprotein M

Yona Kim, Jun Seo Goo, Il Yong Kim, Ji Eun Kim, Moon Hwa Kwak, Jun Go, Sunbo Shim, Jin Tae Hong, Dae Youn Hwang, Je Kyung Seong
Pages: 1688-1698
Published online on: 24 September 2014

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Article

Xuebijing attenuates hypotension through the upregulation of angiotensin II type 1 receptor‑associated protein 1 in rats suffering from heat stroke

Zhiguo Pan, Yu Shao, Wenpeng Dong, Chenxi Liu, Yi  Chen, Hui Jin, Liqun Tang, Junming Qiu, Lei Su
Pages: 1699-1705
Published online on: 29 September 2014

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Article

Palmitic acid exerts pro‑inflammatory effects on vascular smooth muscle cells by inducing the expression of C‑reactive protein, inducible nitric oxide synthase and tumor necrosis factor‑α

Di Wu, Juntian Liu, Xiaoming Pang, Shuyue Wang, Jingjing Zhao, Xiaolu Zhang, Liuxin Feng
Pages: 1706-1712
Published online on: 22 September 2014

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Article

Oxidized S100A4 inhibits the activation of protein phosphatase 5 through S100A1 in MKN‑45 gastric carcinoma cells

Mitsumasa Tsuchiya, Fuminori Yamaguchi, Seiko Shimamoto, Tomohito Fujimoto, Hiroshi Tokumitsu, Masaaki Tokuda, Ryoji Kobayashi
Pages: 1713-1719
Published online on: 29 September 2014

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Article

Effects of icariin on the regulation of the OPG‑RANKL‑RANK system are mediated through the MAPK pathways in IL‑1β‑stimulated human SW1353 chondrosarcoma cells

Zeming Wang, Li Ding, Sihan Zhang, Tao Jiang, Yongmian Yang, Rongheng Li
Pages: 1720-1726
Published online on: 30 September 2014

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Journal Cover
March-2026 Volume 57 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Ginkgolide C alleviates atherosclerosis via activating Nrf2 to inhibit ROS‑dependent NLRP3 inflammasome activation

Rui Zhang
Article Number: 75
Published online on: 27 January 2026

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Review Open Access

MicroRNA‑microbiome cross‑kingdom networks drive inflammatory bowel disease through dynamic regulatory ecosystems (Review)

Liping Liang, Xiaoyan Liu, Bang Li, Huyi Lei, Zibo Tang, Shijie Mai, Chenghai Yang, Yongjian Zhou, Shaoheng Zhang, Le Liu
Article Number: 74
Published online on: 27 January 2026

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Review Open Access

Mechanistic insights into pancreatic cancer progression from circadian rhythm disruption and gut microbiota dysbiosis (Review)

Yang Liu, Yongfeng Li, Heng Ma, Shichang Deng, Chao Cheng
Article Number: 73
Published online on: 26 January 2026

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Retraction Open Access

[Retracted] miR‑124‑3p inhibits the viability and motility of glioblastoma multiforme by targeting RhoG  

Shan Cai, Chao-Jia Shi, Jian-Xiang Lu, Yan-Pei Wang, Tian Yuan, Xiang-Peng Wang
Article Number: 72
Published online on: 26 January 2026

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Review Open Access

Natural products as multi‑target therapies for sepsis‑induced myocardial dysfunction (Review)

Fei Tang, Dong Liu, Shi-Chao Zhu, Hui-Min Zhou, Xue-Wen Qiu
Article Number: 71
Published online on: 22 January 2026

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Review Open Access

MTHFR‑folate axis as a modulator of the epigenetic landscape in autoimmune diseases (Review)

Pablo Michael Navarro‑Rodríguez, Ramón Francisco Bajeca‑Serrano, Francisco Javier Turrubiates‑Hernández, Hazael Ramiro Ceja‑Gálvez, Jorge Hernández‑Bello, Cristian Oswaldo Hernández‑Ramírez, Saúl Ramírez‑de Los Santos, José Francisco Muñoz‑Valle
Article Number: 70
Published online on: 22 January 2026

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Article Open Access

Natural compound 5,7,8‑trimethoxyflavone mitigates radiation‑induced lung injury by suppressing EMT and PI3K/Akt pathway

Cui-Cui Gong, Hua-Kang Li, Yuan-Zhen Mi, Jun-Yang Chen, Zeng-Yi Fang, Shun-Lian Fu, Li Quan, Bing Lin, Jin-Yi Lang, Qiu Chen, Ke Xu, Mei-Hua Chen
Article Number: 69
Published online on: 21 January 2026

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Review Open Access

Epigenetic dysregulation of B‑cells in autoimmune diseases and lymphomas (Review)

Yuxing Li, Yujiao Gong, Jiaxing Zhao, Rensen Ran
Article Number: 68
Published online on: 21 January 2026

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Review Open Access

Research progress on the effects of macrophage‑derived exosomes on muscle factors IGF‑1 and FGF‑2 mediating musculoskeletal crosstalk molecular signaling pathway on bone metabolism (Review)

Ruo-Mei Cui, Mai Zheng, Jian-Bin Hong, Zheng-Xiang Wang, Yu-Fang Cun, Shu-Ji Gao, Yan-Lin Zhu, Zi-Bin Yang, Ming-Wei Liu
Article Number: 67
Published online on: 21 January 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA SNHG20 promotes bladder cancer via activating the Wnt/β‑catenin signalling pathway

Qingsong Zhao, Saiyue Gao, Qingyan Du, Ye Liu
Article Number: 66
Published online on: 21 January 2026

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Review Open Access

Mangiferin in human disease: Multifaceted mechanisms and applications (Review)

Yaling Dai, Qiuling Huang, Mengquan Tan, Zhifu Wang, Cai Jiang, Zheng Liu, Shenghang Zhang, Siyuan Song
Article Number: 65
Published online on: 21 January 2026

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Article

Deciphering the CAF‑LCN2 axis: Key to overcoming anti‑PD‑L1 immunotherapy resistance in lung cancer

Dan Xiao, Jing Yang, Jianying Zhou, Zhenzhen Hu, Ting Zhang
Article Number: 64
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] DDAH2 alleviates myocardial fibrosis in diabetic cardiomyopathy through activation of the DDAH/ADMA/NOS/NO pathway in rats

Zhen-Dong Zhu, Ji-Ming Ye, Xue-Mei Fu, Xue-Chang Wang, Ji-Yun Ye, Xin-Ran Wu, Peng Hua, Yu-Qiong Liao, Wei Xuan, Jin-Lan Duan, Wei-Yuan Li, Hui Fu, Zhong-Hua Xia, Xuan Zhang
Article Number: 63
Published online on: 19 January 2026

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Review Open Access

Beyond hepatic stellate cell heterogeneity: Resolving fibrosis, restoring regeneration (Review)

Chang Gao, Guiqing Chen, Hongyan Jia, Hong Zhu, Yun Cai, Dakai Yang, Kai Zhao
Article Number: 62
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 61
Published online on: 14 January 2026

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Review Open Access

Harnessing MSC‑derived exosomes to modulate the pathophysiology of ASD: Recent advances and therapeutic implications (Review)

Zhaojian Sun, Nouman Amjad, Majid Muhammad, Zhiyuan Li
Article Number: 60
Published online on: 13 January 2026

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Retraction Open Access

[Retracted] Mechanism of cell death induced by silica nanoparticles in hepatocyte cells is by apoptosis

Ye Yang, Xinjing Du, Qiang Wang, Jianwei Liu, Enguo Zhang, Linlin Sai, Cheng Peng, Martin F. Lavin, Abrey Jie Yeo, Xu Yang, Hua Shao, Zhongjun Du
Article Number: 59
Published online on: 12 January 2026

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Review Open Access

ZG16B: A key regulator of tumor progression and immune microenvironment modulation in cancer (Review)

Xing-Ming Chen, Yu-Bo Liang, Jin-Xiang Zuo, Zi-Sheng Yang, Le-Yu Zhang, Xin-Yu Zhang, Ping Wan, Yang Ke
Article Number: 58
Published online on: 09 January 2026

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Retraction Open Access

[Retracted] Silica nanoparticles induce cardiomyocyte apoptosis via the mitochondrial pathway in rats following intratracheal instillation

Zhongjun Du, Shangya Chen, Guanqun Cui, Ye Yang, Enguo Zhang, Qiang Wang, Martin F. Lavin, Abrey J. Yeo, Cunxiang Bo, Yu Zhang, Chao Li, Xiaoshan Liu, Xu Yang, Cheng Peng, Hua Shao
Article Number: 57
Published online on: 05 January 2026

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Review Open Access

Role of cuproptosis in digestive system tumors (Review)

Li Zhang, Yongpeng Cheng, Lulu Tang, Jiaxing Zhu, Biguang Tuo
Article Number: 56
Published online on: 02 January 2026

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Review Open Access

Environmental exposure to air pollution and climate: Intersecting the impact on ear and nose health and chemosensory function (Review)

Yu-Chen Zhang, Lei Zhang, Ping-Ting Zhou, Zi-Hui Xie, Wen-Jie Zhang, Min Fan, Yan-Xun Han, Ye-Hai Liu, Yu-Chen Liu
Article Number: 55
Published online on: 31 December 2025

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Review Open Access

Role and mechanisms of ferroptosis in cognitive impairment: From molecular pathways to therapeutic targets (Review)

Shenghui Ge, Deyue Kong, Shuyue Fan, Yi Luo, Xiao Yin, Zehua Jin, Wenqing Xia, Jianhua Ma
Article Number: 54
Published online on: 30 December 2025

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Review Open Access

The GPR124‑Wnt‑PPARγ regulatory axis: Molecular mechanisms and therapeutic implications in chronic inflammatory diseases (Review)

Ming-Wang Cui, Si-Yu Tao, Tao Wen, Zhu-Ling Guo
Article Number: 53
Published online on: 30 December 2025

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Review Open Access

Advances in RPGR gene therapy for X‑linked retinitis pigmentosa: From preclinical insights to clinical application (Review)

Yushan Long, Jia Qi, Wenliang Zhang, Huan Qin, Kai Yao
Article Number: 52
Published online on: 30 December 2025

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Journal Cover
April-2026 Volume 57 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Role of vascular smooth muscle cell pathobiology in sepsis‑induced vasoplegia (Review)

Hang Ruan, Xiao-Yan Shen, Shi-Yan Liu, Shu-Sheng Li
Article Number: 87
Published online on: 06 February 2026

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Review Open Access

Signalling pathways regulated by FSTL1 in inflammation and potential therapeutic applications (Review)

Changliang Ma, Jingxin Li, Wenting Jiang, Xiaoqiang Chen, Jianquan Liu, Xu Tao, Wencui Li, Zhiqin Deng, Zhe Zhao
Article Number: 86
Published online on: 05 February 2026

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Article Open Access

Hypothermic machine perfusion protects DCD graft liver from ischemia‑reperfusion injury by enhancing macrophage efferocytosis via KLF2‑NLRP3 signaling

Qin Deng, Zhongzhong Liu, Qifa Ye, Jia Liu, Zhihui Fu, Xingjian Zhang, Jun Luo, Zhongshan Lu, Pengpeng Yue, Jiansheng Xiao, Qi Xiao
Article Number: 85
Published online on: 05 February 2026

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Mechanistic advances in exercise‑mediated regulation of autophagy dysfunction in Alzheimer's disease (Review)

Wei Li, Wen-Hong Wang, Yi Song, Xu-Jiong Li, Yan Li, Xia Wang, Ting-Ting Tian, Xiao Huang, Li Zhao
Article Number: 84
Published online on: 04 February 2026

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Correction Open Access

[Corrigendum] p57KIP2‑mediated inhibition of human trophoblast apoptosis and promotion of invasion in vitro

Guo-Qian He, Guang-Yu Liu, Wen-Ming Xu, Hui-Juan Liao, Xing-Hui Liu, Guo-Lin He
Article Number: 83
Published online on: 04 February 2026

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Review Open Access

Lipid droplets beyond storage: Cellular metabolic modulator in the diabetic heart (Review)

Yongchun Liang, Xinbiao Fan, Xiaofei Geng, Yunfeng Jia, Wenyu Shang, Xitong Sun, Jun Ge, Guijun Ye, Boyu Zhu, Zheng Zhang, Yuxin Kang, Xiaoyu Shan, Junping Zhang
Article Number: 82
Published online on: 03 February 2026

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Review Open Access

IMP metabolic mechanisms and IMPDH targeting strategies in tumor metabolic reprogramming and therapy (Review)

Hao Zhu, Hao Wang, Xia Li, Weisong Zhang, Yihao Wang, Qingze Tan, Dongxu Ying, Zhan Shi, Jianxiang Song
Article Number: 81
Published online on: 03 February 2026

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Article Open Access

Ebastine targets HER2/HER3 signaling and cancer stem cell traits to overcome trastuzumab resistance in HER2‑positive breast cancer

Eunsun Jung, Ji Young Kim, Dongmi Ko, Juyeon Seo, Sang Yoon Lee, Daeun Lee, Subeen Kim, Minsu Park, Seongjae Kim, Soeun Park, Kyoungmin Lee, Yong Koo Kang, Kee Dal Nam, Yoon-Jae Kim, Jae Hong Seo
Article Number: 80
Published online on: 02 February 2026

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Correction Open Access

[Corrigendum] Inhibition of acid‑sensing ion channel 1a attenuates acid‑induced activation of autophagy via a calcium signaling pathway in articular chondrocytes

Wen-Fan Gao, Ya-Yun Xu, Jin-Fang Ge, Fei-Hu Chen
Article Number: 79
Published online on: 02 February 2026

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Review Open Access

Immunological mechanisms and novel therapeutic strategies for sepsis‑associated acute kidney injury (Review)

Lu Xu, Wei Jiang, Lin Song, Jing Wang, Jiangquan Yu, Ruiqiang Zheng
Article Number: 78
Published online on: 30 January 2026

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Correction Open Access

[Corrigendum] Role of Smad3 signaling in the epithelial‑mesenchymal transition of the lens epithelium following injury

Fanlan Meng, Jun Li, Xiao Yang, Xiaoyong Yuan, Xin Tang
Article Number: 77
Published online on: 29 January 2026

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Review Open Access

Spatial metabolomics: A new tool for unravelling the metabolic disorders and heterogeneity in diabetic kidney disease (Review)

Hanfei Li, Yuxi Li, Bo Zhang, Wenhao Cheng, Guowei Ma, Jin Rong, Shiru Duan, Di Feng, Tingting Zhao
Article Number: 76
Published online on: 29 January 2026

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