Journal Articles

Article Open Access

Glucocorticoid receptor overexpression slightly shifts microRNA expression patterns in triple-negative breast cancer

Dominik Buschmann, Ricardo González, Benedikt Kirchner, Claudia Mazzone, Michael W. Pfaffl, Gustav Schelling, Ortrud Steinlein, Marlene Reithmair

Pages: 1765-1776 Published online on: 27 March 2018
Article Open Access

Long noncoding RNA LINC01296 promotes tumor growth and progression by sponging miR-5095 in human cholangiocarcinoma

Dawei Zhang, Haiyan Li, Juping Xie, Decan Jiang, Liangqi Cao, Xuewei Yang, Ping Xue, Xiaofeng Jiang

Pages: 1777-1786 Published online on: 05 April 2018
Article Open Access

Effects of three-dimensional collagen scaffolds on the expression profiles and biological functions of glioma cells

Wei Jia, Xingjun Jiang, Weidong Liu, Lei Wang, Bin Zhu, Hecheng Zhu, Xingdong Liu, Meizuo Zhong, Dan Xie, Wei Huang, Wenting Jia, Shasha Li, Xuxu Liu, Xiang Zuo, Damei Cheng, Jianwu Dai, Caiping Ren

Pages: 1787-1800 Published online on: 20 March 2018
Article Open Access

MicroRNA-671-3p inhibits the development of breast cancer: A study based on in vitro experiments, in-house quantitative polymerase chain reaction and bioinformatics analysis

Dan-Dan Xiong, Hao Chen, Rong-Quan He, Ai-Hua Lan, Jin-Cai Zhong, Gang Chen, Zhen-Bo Feng, Kang-Lai Wei

Pages: 1801-1814 Published online on: 28 March 2018
Article Open Access

Upregulation of E‑cadherin expression mediated by a novel dsRNA suppresses the growth and metastasis of bladder cancer cells by inhibiting β-catenin/TCF target genes

Chuanchang Li, Jiaxuan Liu, Qingsong Zhang, Kai Cui, Qiangqiang Ge, Chenghe Wang, Zhong Chen

Pages: 1815-1826 Published online on: 29 March 2018
Article Open Access

β‑catenin nuclear translocation induced by HIF‑1α overexpression leads to the radioresistance of prostate cancer

Yong Luo, Mingchuan Li, Xuemei Zuo, Spyridon P. Basourakos, Jiao Zhang, Jiahui Zhao, Yili Han, Yunhua Lin, Yongxing Wang, Yongguang Jiang, Ling Lan

Pages: 1827-1840 Published online on: 12 April 2018
Article Open Access

S-phase kinase-associated protein 2 is involved in epithelial-mesenchymal transition in methotrexate-resistant osteosarcoma cells

Lu Ding, Chengwei Wang, Yong Cui, Xiaoping Han, Yang Zhou, Jingping Bai, Rong Li

Pages: 1841-1852 Published online on: 29 March 2018
Article Open Access

Autophagy inhibition enhances radiosensitivity of Eca‑109 cells via the mitochondrial apoptosis pathway

Hua Tao, Pudong Qian, Jincheng Lu, Yesong Guo, Huanfeng Zhu, Feijiang Wang

Pages: 1853-1862 Published online on: 29 March 2018
Article Open Access

Increased level of cell-derived microparticles in the cyst fluids of odontogenic keratocysts

Qi-Wen Man, Wen-Qun Zhong, Jian-Gang Ren, Jin-Yuan Liu, Yue-Yu Zheng, Rui-Fang Li, B. Fidele Nyimi, Gang Chen, Yi-Fang Zhao, Bing Liu

Pages: 1863-1874 Published online on: 05 April 2018
Article Open Access

Preclinical evaluation of a novel engineered recombinant human anti-CD44v6 antibody for potential use in radio-immunotherapy

Anja C. Mortensen, Diana Spiegelberg, Anna-Karin Haylock, Hans Lundqvist, Marika Nestor

Pages: 1875-1885 Published online on: 11 April 2018
Article Open Access

LTBP2 promotes the migration and invasion of gastric cancer cells and predicts poor outcome of patients with gastric cancer

Jun Wang, Wen-Jia Liang, Guang-Tao Min, Hong-Peng Wang, Wei Chen, Nan Yao

Pages: 1886-1898 Published online on: 04 April 2018
Article Open Access

Metformin inhibits ovarian cancer via decreasing H3K27 trimethylation

Guiju Tang, Jianfeng Guo, Yapei Zhu, Zaiju Huang, Ting Liu, Jing Cai, Lili Yu, Zehua Wang

Pages: 1899-1911 Published online on: 29 March 2018
Article Open Access

KIFC1, a novel potential prognostic factor and therapeutic target in hepatocellular carcinoma

Xiaowei Fu, Yaqiong Zhu, Bingbing Zheng, Yeqing Zou, Chao Wang, Peng Wu, Jun Wang, Haimin Chen, Pengcheng Du, Bo Liang, Lu Fang

Pages: 1912-1922 Published online on: 29 March 2018
Article Open Access

Tumor-suppressing effects of microRNA-612 in bladder cancer cells by targeting malic enzyme 1 expression

Mengnan Liu, Yifan Chen, Bisheng Huang, Shiyu Mao, Keke Cai, Longsheng Wang, Xudong Yao

Pages: 1923-1933 Published online on: 29 March 2018
Article Open Access

Decreased expression of SFRP2 promotes development of the pituitary corticotroph adenoma by upregulating Wnt signaling

Jie Ren, Fangfang Jian, Hong Jiang, Yuhao Sun, Sijian Pan, Changwei Gu, Xiao Chen, Weiqing Wang, Guang Ning, Liuguan Bian, Qingfang Sun

Pages: 1934-1946 Published online on: 03 April 2018
Article

Metabolome analysis of esophageal cancer tissues using capillary electrophoresis-time-of-flight mass spectrometry

Masanori Tokunaga, Kenjiro Kami, Soji Ozawa, Junya Oguma, Akihito Kazuno, Hayato Miyachi, Yoshiaki Ohashi, Masatoshi Kusuhara, Masanori Terashima

Pages: 1947-1958 Published online on: 28 March 2018
Article

Arsenic disulfide‑induced apoptosis and its potential mechanism in two‑ and three‑dimensionally cultured human breast cancer MCF‑7 cells

Yuxue Zhao, Kenji Onda, Bo Yuan, Sachiko Tanaka, Anna Kiyomi, Kentaro Sugiyama, Munetoshi Sugiura, Norio Takagi, Toshihiko Hirano

Pages: 1959-1971 Published online on: 04 April 2018
Article

Mutational burden of resectable pancreatic cancer, as determined by whole transcriptome and whole exome sequencing, predicts a poor prognosis

Elisa Grassi, Sandra Durante, Annalisa Astolfi, Giuseppe Tarantino, Valentina Indio, Eva Freier, Silvia Vecchiarelli, Claudio Ricci, Riccardo Casadei, Francesca Formica, Daria Filippini, Francesca Comito, Carla Serra, Donatella Santini, Antonietta D' Errico, Francesco Minni, Guido Biasco, Mariacristina Di Marco

Pages: 1972-1980 Published online on: 29 March 2018
Article

Phosphatidylserine-exposing cells contribute to the hypercoagulable state in patients with multiple myeloma

Li Guo, Dongxia Tong, Muxin Yu, Yan Zhang, Tao Li, Chunxu Wang, Peng Zhou, Jiaqi Jin, Baorong Li, Yingmiao Liu, Ruipeng Liu, Valerie A. Novakovic, Zengxiang Dong, Ye Tian, Junjie Kou, Yayan Bi, Jin Zhou, Jialan Shi

Pages: 1981-1990 Published online on: 03 April 2018
Article

Biotinylation enhances the anticancer effects of 15d‑PGJ2 against breast cancer cells

Christelle Colin, Maxime Meyer, Claudia Cerella, Alexandra Kleinclauss, Gérald Monard, Michel Boisbrun, Marc Diederich, Stéphane Flament, Isabelle Grillier-Vuissoz, Sandra Kuntz

Pages: 1991-2000 Published online on: 28 March 2018
Article

Silencing of ASPP2 promotes the proliferation, migration and invasion of triple-negative breast cancer cells via the PI3K/AKT pathway

Tianqi Wu, Hongming Song, Dan Xie, Bingkun Zhao, Hui Xu, Chenyang Wu, Kaiyao Hua, Yijun Deng, Changle Ji, Jiashu Hu, Lin Fang

Pages: 2001-2010 Published online on: 20 March 2018
Article

PPP2R2D, a regulatory subunit of protein phosphatase 2A, promotes gastric cancer growth and metastasis via mechanistic target of rapamycin activation

Shijun Yu, Li Li, Qiong Wu, Ning Dou, Yandong Li, Yong Gao

Pages: 2011-2020 Published online on: 20 March 2018
Article

Chaperonin-containing T‑complex protein 1 subunit 8 promotes cell migration and invasion in human esophageal squamous cell carcinoma by regulating α-actin and β-tubulin expression

Xiaojing Yang, Hanru Ren, Yuhui Shao, Yi Sun, Lihua Zhang, Hongling Li, Xiulong Zhang, Xinmiao Yang, Weiwei Yu, Jie Fu

Pages: 2021-2030 Published online on: 27 March 2018
Article

p38 inhibitor inhibits the apoptosis of cowanin-treated human colorectal adenocarcinoma cells

Nittiya Chowchaikong, Sirinun Nilwarangkoon, Surat Laphookhieo, Chantra Tanunyutthawongse, Ramida Watanapokasin

Pages: 2031-2040 Published online on: 03 April 2018
Article

Combination of TP53 and AGR3 to distinguish ovarian high-grade serous carcinoma from low-grade serous carcinoma

Chunping Qiu, Yu Wang, Xiao Wang, Qing Zhang, Yinuo Li, Ying Xu, Chengjuan Jin, Hualei Bu, Wenxin Zheng, Xingsheng Yang, Nan Lu, Beihua Kong

Pages: 2041-2050 Published online on: 04 April 2018
Article

Synergistic anti-hepatoma effect of bufalin combined with sorafenib via mediating the tumor vascular microenvironment by targeting mTOR/VEGF signaling

Haiyong Wang, Chenyue Zhang, Huiying Chi, Zhiqiang Meng

Pages: 2051-2060 Published online on: 02 April 2018
Article

Cotylenin A and tyrosine kinase inhibitors synergistically inhibit the growth of chronic myeloid leukemia cells

Fumiyoshi Ikejiri, Yoshio Honma, Takahiro Okada, Takeshi Urano, Junji Suzumiya

Pages: 2061-2068 Published online on: 02 April 2018
Article

Differential expression of Oct3/4 in human breast cancer and normal tissues

Feng-Qi Zhao, Yogi Misra, Da-Biao Li, Marilyn P. Wadsworth, David Krag, Donald Weaver, Joseph Tessitore, Da-Wei Li, Guo Zhang, Qing Tian, Katie Buss

Pages: 2069-2078 Published online on: 29 March 2018
Article

Expression and clinical significance of PD‑1 in hepatocellular carcinoma tissues detected by a novel mouse anti-human PD‑1 monoclonal antibody

Ziwei Li, Bin Li, Dan Peng, Haiyan Xing, Guanying Wang, Pan Li, Jiming Wang, George Ye, Jianhong Chen

Pages: 2079-2092 Published online on: 04 April 2018
Article

Effect of HOXA6 on the proliferation, apoptosis, migration and invasion of colorectal cancer cells

Shasha Wu, Feixiang Wu, Zheng Jiang

Pages: 2093-2100 Published online on: 02 April 2018
Article

The inhibition of heme oxygenase-1 enhances the chemosensitivity and suppresses the proliferation of pancreatic cancer cells through the SHH signaling pathway

Liang Han, Jie Jiang, Qingyong Ma, Zheng Wu, Zheng Wang

Pages: 2101-2109 Published online on: 05 April 2018
Article

Rapid point-of-care testing for epidermal growth factor receptor gene mutations in patients with lung cancer using cell-free DNA from cytology specimen supernatants

Shiho Asaka, Akihiko Yoshizawa, Kazusa Saito, Yukihiro Kobayashi, Hiroshi Yamamoto, Tatsuya Negishi, Rie Nakata, Kazuyuki Matsuda, Akemi Yamaguchi, Takayuki Honda

Pages: 2110-2118 Published online on: 27 March 2018
Article

Lutein inhibits proliferation, invasion and migration of hypoxic breast cancer cells via downregulation of HES1

Yuan Li, Yuekun Zhang, Xiaosa Liu, Mingchen Wang, Peng Wang, Jianbo Yang, Shanfeng Zhang

Pages: 2119-2129 Published online on: 23 March 2018
Article

FOXD1 is targeted by miR-30a-5p and miR-200a-5p and suppresses the proliferation of human ovarian carcinoma cells by promoting p21 expression in a p53-independent manner

Yu Wang, Chunping Qiu, Nan Lu, Zhaojian Liu, Chengjuan Jin, Chenggong Sun, Hualei Bu, Hongfeng Yu, Samina Dongol, Beihua Kong

Pages: 2130-2142 Published online on: 04 April 2018
Article

Antitumour effects and mechanisms of action of the panHER inhibitor, dacomitinib, alone and in combination with the STAT3 inhibitor, S3I-201, in human sarcoma cell lines

Xiaochun Wang, David Goldstein, Philip J. Crowe, Jia-Lin Yang

Pages: 2143-2154 Published online on: 27 March 2018
Article

Different splicing isoforms of ERCC1 affect the expression of its overlapping genes CD3EAP and PPP1R13L, and indicate a potential application in non-small cell lung cancer treatment

Guopei Zhang, Ping Xue, Su Cui, Tao Yu, Mingyang Xiao, Qianye Zhang, Yuan Cai, Cuihong Jin, Jinghua Yang, Shengwen Wu, Xiaobo Lu

Pages: 2155-2165 Published online on: 29 March 2018
Journal Cover

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June-2018
Volume 52 Issue 6

Print ISSN: 1019-6439
Online ISSN: 1791-2423

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