Journal Articles

Review Open Access

Regulation of expression of O6-methylguanine-DNA methyltransferase and the treatment of glioblastoma (Review)

Giulio Cabrini, Enrica Fabbri, Cristiana Lo Nigro, Maria Cristina Dechecchi, Roberto Gambari

Pages: 417-428 Published online on: 29 May 2015
Review

The phosphatidylinositol 3-kinase/Akt and c-Jun N-terminal kinase signaling in cancer: Alliance or contradiction? (Review)

Hua-Fu Zhao, Jing Wang, Shing-Shun Tony To

Pages: 429-436 Published online on: 16 June 2015
Review

Molecular aspects of breast cancer resistance to drugs (Review)

Gloria M. Calaf, Andrea B. Zepeda, Rodrigo L. Castillo, Carolina A. Figueroa, Consuelo Arias, Elías Figueroa, Jorge G. Farías

Pages: 437-445 Published online on: 18 June 2015
Article Open Access

Combining AZD8931, a novel EGFR/HER2/HER3 signalling inhibitor, with AZD5363 limits AKT inhibitor induced feedback and enhances antitumour efficacy in HER2-amplified breast cancer models

Claire Crafter, John P. Vincent, Eric Tang, Phillippa Dudley, Neil H. James, Teresa Klinowska, Barry R. Davies

Pages: 446-454 Published online on: 22 June 2015
Article Open Access

Epigenetic regulation of embryonic stem cell marker miR302C in human chondrosarcoma as determinant of antiproliferative activity of proline-rich polypeptide 1

Karina Galoian, Amir Qureshi, Gianluca D'Ippolito, Paul C. Schiller, Marco Molinari, Andrea L. Johnstone, Shaun P. Brothers, Ana C. Paz, H. T. Temple

Pages: 465-472 Published online on: 18 June 2015
Article Open Access

EBP1 protein modulates the expression of human MHC class II molecules in non-hematopoietic cancer cells

Laura Pisapia, Pasquale Barba, Angela Cortese, Valeria Cicatiello, Franco Morelli, Giovanna Del Pozzo

Pages: 481-489 Published online on: 16 June 2015
Article

TM4SF1 as a prognostic marker of pancreatic ductal adenocarcinoma is involved in migration and invasion of cancer cells

Biao Zheng, Kenoki Ohuchida, Lin Cui, Ming Zhao, Koji Shindo, Kenji Fujiwara, Tatsuya Manabe, Nobuhiro Torata, Taiki Moriyama, Yoshihiro Miyasaka, Takao Ohtsuka, Shunichi Takahata, Kazuhiro Mizumoto, Yoshinao Oda, Masao Tanaka

Pages: 490-498 Published online on: 28 May 2015
Article

EGFR and HER2 signals play a salvage role in MEK1-mutated gastric cancer after MEK inhibition

Takuro Mizukami, Yosuke Togashi, Shunsuke Sogabe, Eri Banno, Masato Terashima, Marco A De Velasco, Kazuko Sakai, Yoshihiko Fujita, Shuta Tomida, Takako Eguchi Nakajima, Narikazu Boku, Kazuto Nishio

Pages: 499-505 Published online on: 16 June 2015
Article

NVP-BKM120 potentiates apoptosis in tumor necrosis factor-related apoptosis-inducing ligand-resistant glioma cell lines via upregulation of Noxa and death receptor 5

Kimberly A. Foster, Esther P. Jane, Daniel R. Premkumar, Alejandro Morales, Ian F. Pollack

Pages: 506-516 Published online on: 05 June 2015
Article

Matrine-induced autophagy regulated by p53 through AMP-activated protein kinase in human hepatoma cells

Shan-Bu Xie, Xing-Xing He, Shu-Kun Yao

Pages: 517-526 Published online on: 28 May 2015
Article

The stress hormone norepinephrine increases migration of prostate cancer cells in vitro and in vivo

Antonio Barbieri, Sabrina Bimonte, Giuseppe Palma, Antonio Luciano, Domenica Rea, Aldo Giudice, Giosuè Scognamiglio, Elvira La Mantia, Renato Franco, Sisto Perdonà, Ottavio De Cobelli, Matteo Ferro, Silvia Zappavigna, Paola Stiuso, Michele Caraglia, Claudio Arra

Pages: 527-534 Published online on: 08 June 2015
Article

MicroRNA profiles in cisplatin-induced apoptosis of hepatocellular carcinoma cells

Miwa Miyata, Asahiro Morishita, Teppei Sakamoto, Akiko Katsura, Kiyohito Kato, Tomoko Nishioka, Yuka Toyota, Koji Fujita, Emiko Maeda, Takako Nomura, Joji Tani, Hisaaki Miyoshi, Hirohito Yoneyama, Hideki Kobara, Shintaro Fujiwara, Noriko Nishiyama, Hisakazu Iwama, Takashi Himoto, Mitsuomi Hirashima, Tsutomu Masaki

Pages: 535-542 Published online on: 05 June 2015
Article

C-reactive protein is a biomarker of AFP-negative HBV-related hepatocellular carcinoma

Sha She, Yi Xiang, Min Yang, Xiangchun Ding, Xiaoyan Liu, Lina Ma, Qing Liu, Bin Liu, Zhenhui Lu, Shiying Li, Yi Liu, Xiaoping Ran, Xiaoming Xu, Huaidong Hu, Peng Hu, Dazhi Zhang, Hong Ren, Yixuan Yang

Pages: 543-554 Published online on: 10 June 2015
Article

The antitumor effects of oncolytic adenovirus H101 against lung cancer

Jie Lei, Qi-Hua Li, Ju-Lun Yang, Feng Liu, Li Wang, Wen-Mang Xu, Wen-Xing Zhao

Pages: 555-562 Published online on: 11 June 2015
Article

MHY218-induced apoptotic cell death is enhanced by the inhibition of autophagy in AGS human gastric cancer cells

Pyoung Rak Choi, Yong Jung Kang, Bokyung Sung, Jae Hyun Kim, Hyung Ryong Moon, Hae Young Chung, Sung Eun Kim, Moo In Park, Seun Ja Park, Nam Deuk Kim

Pages: 563-572 Published online on: 04 June 2015
Article

Sulphur alters NFκB-p300 cross-talk in favour of p53-p300 to induce apoptosis in non-small cell lung carcinoma

Shilpi Saha, Pushpak Bhattacharjee, Deblina Guha, Kirti Kajal, Poulami Khan, Sreeparna Chakraborty, Shravanti Mukherjee, Shrutarshi Paul, Rajkumar Manchanda, Anil Khurana, Debadatta Nayak, Rathin Chakrabarty, Gaurisankar Sa, Tanya Das

Pages: 573-582 Published online on: 22 June 2015
Article

Increased phosphorylation on residue S795 of the retinoblastoma protein in esophageal adenocarcinoma

Akueni L. Davelaar, Danielle Straub, Kaushal B. Parikh, Liana Lau, Paul Fockens, Kausilia K. Krishnadath

Pages: 583-591 Published online on: 09 June 2015
Article

Huachansu mediates cell death in non-Hodgkin's lymphoma by induction of caspase-3 and inhibition of MAP kinase

Ekem T. Efuet, Xiao-Ping Ding, Carrie Cartwright, Yong Pan, Lorenzo Cohen, Peiying Yang

Pages: 592-600 Published online on: 11 June 2015
Article

Target-specific cytotoxic effects on HER2-expressing cells by the tripartite fusion toxin ZHER2:2891-ABD-PE38X8, including a targeting affibody molecule and a half-life extension domain

Hao Liu, Johan Seijsing, Fredrik Y. Frejd, Vladimir Tolmachev, Torbjörn Gräslund

Pages: 601-609 Published online on: 04 June 2015
Article

Ape1 regulates WNT/β-catenin signaling through its redox functional domain in pancreatic cancer cells

Shaojie Jiang, Lina Zhu, Haimei Tang, Miaofeng Zhang, Zhihua Chen, Jian Fei, Baosan Han, Gang-Ming Zou

Pages: 610-620 Published online on: 12 June 2015
Article

Inactivation of BLU is associated with methylation of Sp1-binding site of BLU promoter in gastric cancer

Kunting Xiao, Zhuwen Yu, Dong-Tao Shi, Zhe Lei, Hongbing Chen, Jian Cao, Wenyan Tian, Weichang Chen, Hong-Tao Zhang

Pages: 621-631 Published online on: 04 June 2015
Article

Protective effects of hepatic stellate cells against cisplatin-induced apoptosis in human hepatoma G2 cells

Lei Zhang, Yi Li, Liang Qiao, Yongxun Zhao, Yucai Wei, Yumin Li

Pages: 632-640 Published online on: 28 May 2015
Article

SRF-miR‑29b-MMP2 axis inhibits NSCLC invasion and metastasis

Hong-Yan Wang, Yong-Sheng Tu, Jie Long, Hui-Qiu Zhang, Cui-Ling Qi, Xiao-Bin Xie, Shu-Hua Li, Ya-Jie Zhang

Pages: 641-649 Published online on: 05 June 2015
Article

Estrogen-dependent expression and subcellular localization of the tight junction protein claudin-4 in HEC-1A endometrial cancer cells

Maria E. Cuevas, Jenna M. Gaska, Andrea C. Gist, Jonathan M. King, Rebecca A. Sheller, Maria C. Todd

Pages: 650-656 Published online on: 04 June 2015
Article

Silencing of Livin inhibits tumorigenesis and metastasis via VEGF and MMPs pathway in lung cancer

Xian Lin, Hong-Ru Li, Xiao-Fen Lin, Mei-E Yu, Xun-Wei Tu, Zhi-Dan Hua, Ming Lin, Neng-Luan Xu, Li-Li Han, Yu-Sheng Chen

Pages: 657-667 Published online on: 19 June 2015
Article

Gene therapy targeting hepatocellular carcinoma by a dual-regulated oncolytic adenovirus harboring the focal adhesion kinase shRNA

Yang Gao, Yayun Zhu, Xinyu Huang, Kaixing Ai, Qi Zheng, Zhou Yuan

Pages: 668-678 Published online on: 12 June 2015
Article

Autophagy is involved in recombinant Newcastle disease virus (rL-RVG)-induced cell death of stomach adenocarcinoma cells in vitro

Xu-Feng Bu, Mu-Bing Wang, Zhi-Jian Zhang, Ying-Hai Zhao, Mi Li, Yu-Lan Yan

Pages: 679-689 Published online on: 09 June 2015
Article

CXCL5/CXCR2 axis promotes bladder cancer cell migration and invasion by activating PI3K/AKT-induced upregulation of MMP2/MMP9

Ye Gao, Zhenfeng Guan, Jiaqi Chen, Hongjun Xie, Zhao Yang, Jinhai Fan, Xinyang Wang, Lei Li

Pages: 690-700 Published online on: 09 June 2015
Article

Ginsenoside Rg3 suppresses FUT4 expression through inhibiting NF-κB/p65 signaling pathway to promote melanoma cell death

Xiu Shan, Li Li Tian, Yu Mei Zhang, Xiao Qi Wang, Qiu Yan, Ji Wei Liu

Pages: 701-709 Published online on: 18 June 2015
Article

MicroRNA-26a/b directly regulate La-related protein 1 and inhibit cancer cell invasion in prostate cancer

Mayuko Kato, Yusuke Goto, Ryosuke Matsushita, Akira Kurozumi, Ichiro Fukumoto, Rika Nishikawa, Shinichi Sakamoto, Hideki Enokida, Masayuki Nakagawa, Tomohiko Ichikawa, Naohiko Seki

Pages: 710-718 Published online on: 10 June 2015
Article

BM-MSCs promote prostate cancer progression via the conversion of normal fibroblasts to cancer-associated fibroblasts

Simeng Wen, Yuanjie Niu, Shuyuan Yeh, Chawnshang Chang

Pages: 719-727 Published online on: 22 June 2015
Article

Overexpression of hypoxia-inducible factor 1α induces migration and invasion through Notch signaling

Quan Tian, Yan Xue, Wei Zheng, Rong Sun, Wei Ji, Xinyang Wang, Ruifang An

Pages: 728-738 Published online on: 18 June 2015
Article

Lung cancer trend in England for the period of 2002 to 2011 and projections of future burden until 2020

Olufemi O. Olajide, John K. Field, Michael M.P.A. Davies, Michael W. Marcus

Pages: 739-746 Published online on: 15 June 2015
Article

Growth inhibition of luteolin on HepG2 cells is induced via p53 and Fas/Fas-ligand besides the TGF-β pathway

Su Bog Yee, Hye Joung Choi, Sang Woon Chung, Dong Heun Park, Bokyung Sung, Hae Young Chung, Nam Deuk Kim

Pages: 747-754 Published online on: 18 June 2015
Article

Acetylcarnitine potentiates the anticarcinogenic effects of butyrate on SW480 colon cancer cells

Ihsan Elimrani, Serge Dionne, Dan Saragosti, Ijaz Qureshi, Emile Levy, Edgar Delvin, Ernest G. Seidman

Pages: 755-763 Published online on: 04 June 2015
Article

Influence of fatty acid synthase inhibitor orlistat on the DNA repair enzyme O6-methylguanine-DNA methyltransferase in human normal or malignant cells in vitro

Giorgia Cioccoloni, Laura Bonmassar, Elena Pagani, Simona Caporali, Maria Pia Fuggetta, Enzo Bonmassar, Stefania D'Atri, Angelo Aquino

Pages: 764-772 Published online on: 29 May 2015
Article

Inhibitory effect of vitamin K1 on growth and polyamine biosynthesis of human gastric and colon carcinoma cell lines

Michele Linsalata, Antonella Orlando, Valeria Tutino, Maria Notarnicola, Benedetta D'Attoma, Francesco Russo

Pages: 773-781 Published online on: 04 June 2015
Article

Elevated cyclin A associated kinase activity promotes sensitivity of metastatic human cancer cells to DNA antimetabolite drug

Jin Wang, Hailin Yin, Ashwini Panandikar, Varsha Gandhi, Subrata Sen

Pages: 782-790 Published online on: 08 June 2015
Correction Open Access

[Corrigendum] Aberrant methylation of CXCL12 in non-small cell lung cancer is associated with an unfavorable prognosis.

Makoto Suzuki, Sherif Mohamed, Takahiro Nakajima, Rieko Kubo, Lei Tian, Taiki Fujiwara, Hidemi Suzuki, Kaoru Nagato, Masako Chiyo, Shinichiro Motohashi, Kazuhiro Yasufuku, Akira Iyoda, Shigetoshi Yoshida, Yasuo Sekine, Kiyoshi Shibuya, Kenzo Hiroshima, Yukio Nakatani, Ichiro Yoshino, Takehiko Fujisawa

Pages: 791-791 Published online on: 12 June 2015
Journal Cover

Cover Legend PDF

August-2015
Volume 47 Issue 2

Print ISSN: 1019-6439
Online ISSN: 1791-2423

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