Journal Articles
Review
Regulation of expression of O6-methylguanine-DNA methyltransferase and the treatment of glioblastoma (Review)
Giulio Cabrini, Enrica Fabbri, Cristiana Lo Nigro, Maria Cristina Dechecchi, Roberto Gambari
Pages: 417-428 Published online on: 29 May 2015
Review
The phosphatidylinositol 3-kinase/Akt and c-Jun N-terminal kinase signaling in cancer: Alliance or contradiction? (Review)
Hua-Fu Zhao, Jing Wang, Shing-Shun Tony To
Pages: 429-436 Published online on: 16 June 2015
Review
Molecular aspects of breast cancer resistance to drugs (Review)
Gloria M. Calaf, Andrea B. Zepeda, Rodrigo L. Castillo, Carolina A. Figueroa, Consuelo Arias, Elías Figueroa, Jorge G. Farías
Pages: 437-445 Published online on: 18 June 2015
Article
Combining AZD8931, a novel EGFR/HER2/HER3 signalling inhibitor, with AZD5363 limits AKT inhibitor induced feedback and enhances antitumour efficacy in HER2-amplified breast cancer models
Claire Crafter, John P. Vincent, Eric Tang, Phillippa Dudley, Neil H. James, Teresa Klinowska, Barry R. Davies
Pages: 446-454 Published online on: 22 June 2015
Article
Metronomic vinorelbine: Anti-angiogenic activity in vitro in normoxic and severe hypoxic conditions, and severe hypoxia-induced resistance to its anti-proliferative effect with reversal by Akt inhibition
L. Mavroeidis, H. Sheldon, E. Briasoulis, M. Marselos, P. Pappas, A. L. Harris
Pages: 455-464 Published online on: 19 June 2015
Article
Epigenetic regulation of embryonic stem cell marker miR302C in human chondrosarcoma as determinant of antiproliferative activity of proline-rich polypeptide 1
Karina Galoian, Amir Qureshi, Gianluca D'Ippolito, Paul C. Schiller, Marco Molinari, Andrea L. Johnstone, Shaun P. Brothers, Ana C. Paz, H. T. Temple
Pages: 465-472 Published online on: 18 June 2015
Article
Vitamin K2 and cotylenin A synergistically induce monocytic differentiation and growth arrest along with the suppression of c-MYC expression and induction of cyclin G2 expression in human leukemia HL-60 cells
Yasuhisa Maniwa, Takashi Kasukabe, Shunichi Kumakura
Pages: 473-480 Published online on: 04 June 2015
Article
EBP1 protein modulates the expression of human MHC class II molecules in non-hematopoietic cancer cells
Laura Pisapia, Pasquale Barba, Angela Cortese, Valeria Cicatiello, Franco Morelli, Giovanna Del Pozzo
Pages: 481-489 Published online on: 16 June 2015
Article
TM4SF1 as a prognostic marker of pancreatic ductal adenocarcinoma is involved in migration and invasion of cancer cells
Biao Zheng, Kenoki Ohuchida, Lin Cui, Ming Zhao, Koji Shindo, Kenji Fujiwara, Tatsuya Manabe, Nobuhiro Torata, Taiki Moriyama, Yoshihiro Miyasaka, Takao Ohtsuka, Shunichi Takahata, Kazuhiro Mizumoto, Yoshinao Oda, Masao Tanaka
Pages: 490-498 Published online on: 28 May 2015
Article
EGFR and HER2 signals play a salvage role in MEK1-mutated gastric cancer after MEK inhibition
Takuro Mizukami, Yosuke Togashi, Shunsuke Sogabe, Eri Banno, Masato Terashima, Marco A De Velasco, Kazuko Sakai, Yoshihiko Fujita, Shuta Tomida, Takako Eguchi Nakajima, Narikazu Boku, Kazuto Nishio
Pages: 499-505 Published online on: 16 June 2015
Article
NVP-BKM120 potentiates apoptosis in tumor necrosis factor-related apoptosis-inducing ligand-resistant glioma cell lines via upregulation of Noxa and death receptor 5
Kimberly A. Foster, Esther P. Jane, Daniel R. Premkumar, Alejandro Morales, Ian F. Pollack
Pages: 506-516 Published online on: 05 June 2015
Article
Matrine-induced autophagy regulated by p53 through AMP-activated protein kinase in human hepatoma cells
Shan-Bu Xie, Xing-Xing He, Shu-Kun Yao
Pages: 517-526 Published online on: 28 May 2015
Article
The stress hormone norepinephrine increases migration of prostate cancer cells in vitro and in vivo
Antonio Barbieri, Sabrina Bimonte, Giuseppe Palma, Antonio Luciano, Domenica Rea, Aldo Giudice, Giosuè Scognamiglio, Elvira La Mantia, Renato Franco, Sisto Perdonà, Ottavio De Cobelli, Matteo Ferro, Silvia Zappavigna, Paola Stiuso, Michele Caraglia, Claudio Arra
Pages: 527-534 Published online on: 08 June 2015
Article
MicroRNA profiles in cisplatin-induced apoptosis of hepatocellular carcinoma cells
Miwa Miyata, Asahiro Morishita, Teppei Sakamoto, Akiko Katsura, Kiyohito Kato, Tomoko Nishioka, Yuka Toyota, Koji Fujita, Emiko Maeda, Takako Nomura, Joji Tani, Hisaaki Miyoshi, Hirohito Yoneyama, Hideki Kobara, Shintaro Fujiwara, Noriko Nishiyama, Hisakazu Iwama, Takashi Himoto, Mitsuomi Hirashima, Tsutomu Masaki
Pages: 535-542 Published online on: 05 June 2015
Article
C-reactive protein is a biomarker of AFP-negative HBV-related hepatocellular carcinoma
Sha She, Yi Xiang, Min Yang, Xiangchun Ding, Xiaoyan Liu, Lina Ma, Qing Liu, Bin Liu, Zhenhui Lu, Shiying Li, Yi Liu, Xiaoping Ran, Xiaoming Xu, Huaidong Hu, Peng Hu, Dazhi Zhang, Hong Ren, Yixuan Yang
Pages: 543-554 Published online on: 10 June 2015
Article
The antitumor effects of oncolytic adenovirus H101 against lung cancer
Jie Lei, Qi-Hua Li, Ju-Lun Yang, Feng Liu, Li Wang, Wen-Mang Xu, Wen-Xing Zhao
Pages: 555-562 Published online on: 11 June 2015
Article
MHY218-induced apoptotic cell death is enhanced by the inhibition of autophagy in AGS human gastric cancer cells
Pyoung Rak Choi, Yong Jung Kang, Bokyung Sung, Jae Hyun Kim, Hyung Ryong Moon, Hae Young Chung, Sung Eun Kim, Moo In Park, Seun Ja Park, Nam Deuk Kim
Pages: 563-572 Published online on: 04 June 2015
Article
Sulphur alters NFκB-p300 cross-talk in favour of p53-p300 to induce apoptosis in non-small cell lung carcinoma
Shilpi Saha, Pushpak Bhattacharjee, Deblina Guha, Kirti Kajal, Poulami Khan, Sreeparna Chakraborty, Shravanti Mukherjee, Shrutarshi Paul, Rajkumar Manchanda, Anil Khurana, Debadatta Nayak, Rathin Chakrabarty, Gaurisankar Sa, Tanya Das
Pages: 573-582 Published online on: 22 June 2015
Article
Increased phosphorylation on residue S795 of the retinoblastoma protein in esophageal adenocarcinoma
Akueni L. Davelaar, Danielle Straub, Kaushal B. Parikh, Liana Lau, Paul Fockens, Kausilia K. Krishnadath
Pages: 583-591 Published online on: 09 June 2015
Article
Huachansu mediates cell death in non-Hodgkin's lymphoma by induction of caspase-3 and inhibition of MAP kinase
Ekem T. Efuet, Xiao-Ping Ding, Carrie Cartwright, Yong Pan, Lorenzo Cohen, Peiying Yang
Pages: 592-600 Published online on: 11 June 2015
Article
Target-specific cytotoxic effects on HER2-expressing cells by the tripartite fusion toxin ZHER2:2891-ABD-PE38X8, including a targeting affibody molecule and a half-life extension domain
Hao Liu, Johan Seijsing, Fredrik Y. Frejd, Vladimir Tolmachev, Torbjörn Gräslund
Pages: 601-609 Published online on: 04 June 2015
Article
Ape1 regulates WNT/β-catenin signaling through its redox functional domain in pancreatic cancer cells
Shaojie Jiang, Lina Zhu, Haimei Tang, Miaofeng Zhang, Zhihua Chen, Jian Fei, Baosan Han, Gang-Ming Zou
Pages: 610-620 Published online on: 12 June 2015
Article
Inactivation of BLU is associated with methylation of Sp1-binding site of BLU promoter in gastric cancer
Kunting Xiao, Zhuwen Yu, Dong-Tao Shi, Zhe Lei, Hongbing Chen, Jian Cao, Wenyan Tian, Weichang Chen, Hong-Tao Zhang
Pages: 621-631 Published online on: 04 June 2015
Article
Protective effects of hepatic stellate cells against cisplatin-induced apoptosis in human hepatoma G2 cells
Lei Zhang, Yi Li, Liang Qiao, Yongxun Zhao, Yucai Wei, Yumin Li
Pages: 632-640 Published online on: 28 May 2015
Article
SRF-miR‑29b-MMP2 axis inhibits NSCLC invasion and metastasis
Hong-Yan Wang, Yong-Sheng Tu, Jie Long, Hui-Qiu Zhang, Cui-Ling Qi, Xiao-Bin Xie, Shu-Hua Li, Ya-Jie Zhang
Pages: 641-649 Published online on: 05 June 2015
Article
Estrogen-dependent expression and subcellular localization of the tight junction protein claudin-4 in HEC-1A endometrial cancer cells
Maria E. Cuevas, Jenna M. Gaska, Andrea C. Gist, Jonathan M. King, Rebecca A. Sheller, Maria C. Todd
Pages: 650-656 Published online on: 04 June 2015
Article
Silencing of Livin inhibits tumorigenesis and metastasis via VEGF and MMPs pathway in lung cancer
Xian Lin, Hong-Ru Li, Xiao-Fen Lin, Mei-E Yu, Xun-Wei Tu, Zhi-Dan Hua, Ming Lin, Neng-Luan Xu, Li-Li Han, Yu-Sheng Chen
Pages: 657-667 Published online on: 19 June 2015
Article
Gene therapy targeting hepatocellular carcinoma by a dual-regulated oncolytic adenovirus harboring the focal adhesion kinase shRNA
Yang Gao, Yayun Zhu, Xinyu Huang, Kaixing Ai, Qi Zheng, Zhou Yuan
Pages: 668-678 Published online on: 12 June 2015
Article
Autophagy is involved in recombinant Newcastle disease virus (rL-RVG)-induced cell death of stomach adenocarcinoma cells in vitro
Xu-Feng Bu, Mu-Bing Wang, Zhi-Jian Zhang, Ying-Hai Zhao, Mi Li, Yu-Lan Yan
Pages: 679-689 Published online on: 09 June 2015
Article
CXCL5/CXCR2 axis promotes bladder cancer cell migration and invasion by activating PI3K/AKT-induced upregulation of MMP2/MMP9
Ye Gao, Zhenfeng Guan, Jiaqi Chen, Hongjun Xie, Zhao Yang, Jinhai Fan, Xinyang Wang, Lei Li
Pages: 690-700 Published online on: 09 June 2015
Article
Ginsenoside Rg3 suppresses FUT4 expression through inhibiting NF-κB/p65 signaling pathway to promote melanoma cell death
Xiu Shan, Li Li Tian, Yu Mei Zhang, Xiao Qi Wang, Qiu Yan, Ji Wei Liu
Pages: 701-709 Published online on: 18 June 2015
Article
MicroRNA-26a/b directly regulate La-related protein 1 and inhibit cancer cell invasion in prostate cancer
Mayuko Kato, Yusuke Goto, Ryosuke Matsushita, Akira Kurozumi, Ichiro Fukumoto, Rika Nishikawa, Shinichi Sakamoto, Hideki Enokida, Masayuki Nakagawa, Tomohiko Ichikawa, Naohiko Seki
Pages: 710-718 Published online on: 10 June 2015
Article
BM-MSCs promote prostate cancer progression via the conversion of normal fibroblasts to cancer-associated fibroblasts
Simeng Wen, Yuanjie Niu, Shuyuan Yeh, Chawnshang Chang
Pages: 719-727 Published online on: 22 June 2015
Article
Overexpression of hypoxia-inducible factor 1α induces migration and invasion through Notch signaling
Quan Tian, Yan Xue, Wei Zheng, Rong Sun, Wei Ji, Xinyang Wang, Ruifang An
Pages: 728-738 Published online on: 18 June 2015
Article
Lung cancer trend in England for the period of 2002 to 2011 and projections of future burden until 2020
Olufemi O. Olajide, John K. Field, Michael M.P.A. Davies, Michael W. Marcus
Pages: 739-746 Published online on: 15 June 2015
Article
Growth inhibition of luteolin on HepG2 cells is induced via p53 and Fas/Fas-ligand besides the TGF-β pathway
Su Bog Yee, Hye Joung Choi, Sang Woon Chung, Dong Heun Park, Bokyung Sung, Hae Young Chung, Nam Deuk Kim
Pages: 747-754 Published online on: 18 June 2015
Article
Acetylcarnitine potentiates the anticarcinogenic effects of butyrate on SW480 colon cancer cells
Ihsan Elimrani, Serge Dionne, Dan Saragosti, Ijaz Qureshi, Emile Levy, Edgar Delvin, Ernest G. Seidman
Pages: 755-763 Published online on: 04 June 2015
Article
Influence of fatty acid synthase inhibitor orlistat on the DNA repair enzyme O6-methylguanine-DNA methyltransferase in human normal or malignant cells in vitro
Giorgia Cioccoloni, Laura Bonmassar, Elena Pagani, Simona Caporali, Maria Pia Fuggetta, Enzo Bonmassar, Stefania D'Atri, Angelo Aquino
Pages: 764-772 Published online on: 29 May 2015
Article
Inhibitory effect of vitamin K1 on growth and polyamine biosynthesis of human gastric and colon carcinoma cell lines
Michele Linsalata, Antonella Orlando, Valeria Tutino, Maria Notarnicola, Benedetta D'Attoma, Francesco Russo
Pages: 773-781 Published online on: 04 June 2015
Article
Elevated cyclin A associated kinase activity promotes sensitivity of metastatic human cancer cells to DNA antimetabolite drug
Jin Wang, Hailin Yin, Ashwini Panandikar, Varsha Gandhi, Subrata Sen
Pages: 782-790 Published online on: 08 June 2015
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