Journal Articles
Review
Hormone signaling pathways as treatment targets in renal cell cancer (Review)
Anna M. Czarnecka, Magdalena Niedzwiedzka, Camillo Porta, Cezary Szczylik
Pages: 2221-2235 Published online on: 28 March 2016
Review
Interaction between Wnt/β-catenin pathway and microRNAs regulates epithelial-mesenchymal transition in gastric cancer (Review)
Cunen Wu, Yuwen Zhuang, Shan Jiang, Shenlin Liu, Jinyong Zhou, Jian Wu, Yuhao Teng, Baomei Xia, Ruiping Wang, Xi Zou
Pages: 2236-2246 Published online on: 08 April 2016
Review
αβ T-cell receptor bias in disease and therapy (Review)
Chun-Yan Wang, Pei-Fa Yu, Xiao-Bing He, Yong-Xiang Fang, Wen-Yu Cheng, Zhi-Zhong Jing
Pages: 2247-2256 Published online on: 18 April 2016
Article
Potential screening and early diagnosis method for cancer: Tongue diagnosis
Shuwen Han, Xi Yang, Quan Qi, Yuefen Pan, Yongchao Chen, Junjun Shen, Haihong Liao, Zhaoning Ji
Pages: 2257-2264 Published online on: 31 March 2016
Article
Chemosensitizing effect of podophyllotoxin acetate on topoisomerase inhibitors leads to synergistic enhancement of lung cancer cell apoptosis
Wan Gi Hong, Jeong Hyun Cho, Sang-Gu Hwang, Eunah Lee, Jaeseok Lee, Jong-Il Kim, Hong-Duck Um, Jong Kuk Park
Pages: 2265-2276 Published online on: 01 April 2016
Article
In vivo monitoring of CD44+ cancer stem-like cells by γ-irradiation in breast cancer
Mi Hyun Kim, Min Hwan Kim, Kwang Seok Kim, Myung-Jin Park, Jae-Hoon Jeong, Seung Woo Park, Young Hoon Ji, Kwang Il Kim, Tae Sup Lee, Phil Youl Ryu, Joo Hyun Kang, Yong Jin Lee
Pages: 2277-2286 Published online on: 18 April 2016
Article
Tetramethylpyrazine induces differentiation of human umbilical cord-derived mesenchymal stem cells into neuron-like cells in vitro
Chengrui Nan, Li Guo, Zongmao Zhao, Shucheng Ma, Jixiang Liu, Dongdong Yan, Guoqiang Song, Hanjie Liu
Pages: 2287-2294 Published online on: 23 March 2016
Article
Impact of multicellular tumor spheroids as an in vivo‑like tumor model on anticancer drug response
Bianca Galateanu, Ariana Hudita, Carolina Negrei, Rodica‑Mariana Ion, Marieta Costache, Miriana Stan, Dragana Nikitovic, A. Wallace Hayes, Demetrios A. Spandidos, Aristidis M. Tsatsakis, Octav Ginghina
Pages: 2295-2302 Published online on: 01 April 2016
Article
The hepatocyte growth factor antagonist NK4 inhibits indoleamine-2,3-dioxygenase expression via the c-Met-phosphatidylinositol 3-kinase-AKT signaling pathway
Dongdong Wang, Yasushi Saga, Naoto Sato, Toshikazu Nakamura, Osamu Takikawa, Hiroaki Mizukami, Shigeki Matsubara, Hiroyuki Fujiwara
Pages: 2303-2309 Published online on: 14 April 2016
Article
Podoplanin-mediated TGF-β-induced epithelial-mesenchymal transition and its correlation with bHLH transcription factor DEC in TE-11 cells
Yunyan Wu, Qiang Liu, Xu Yan, Yukio Kato, Makiko Tanaka, Sadaki Inokuchi, Tadashi Yoshizawa, Satoko Morohashi, Hiroshi Kijima
Pages: 2310-2320 Published online on: 18 March 2016
Article
Expression and function of CXCL12/CXCR4/CXCR7 in thyroid cancer
Xiaoli Zhu, Qianming Bai, Yongming Lu, Yiqiong Lu, Linlin Zhu, Xiaoyan Zhou, Lijing Wu
Pages: 2321-2329 Published online on: 12 April 2016
Article
Docetaxel induces Bcl-2- and pro-apoptotic caspase-independent death of human prostate cancer DU145 cells
Takeharu Ogura, Yoshiyuki Tanaka, Hiroki Tamaki, Mamoru Harada
Pages: 2330-2338 Published online on: 08 April 2016
Article
Unusual roles of caspase-8 in triple-negative breast cancer cell line MDA-MB-231
Anna De Blasio, Riccardo Di Fiore, Marco Morreale, Daniela Carlisi, Rosa Drago-Ferrante, Mauro Montalbano, Christian Scerri, Giovanni Tesoriere, Renza Vento
Pages: 2339-2348 Published online on: 06 April 2016
Article
Blockade of Notch3 inhibits the stem-like property and is associated with ALDH1A1 and CD44 via autophagy in non-small lung cancer
Yuanyuan Ma, Mingzhen Li, Jiahui Si, Ying Xiong, Fangliang Lu, Jianzhi Zhang, Liyi Zhang, Panpan Zhang, Yue Yang
Pages: 2349-2358 Published online on: 30 March 2016
Article
Knockdown of ROS1 gene sensitizes breast tumor growth to doxorubicin in a syngeneic mouse model
Snigdha Tiash, Ming Jang Chua, Ezharul Hoque Chowdhury
Pages: 2359-2366 Published online on: 23 March 2016
Article
Molecular dysfunctions in acute myeloid leukemia revealed by integrated analysis of microRNA and transcription factor
Xiao-Cong Lin, Yong Xu, Guo-Ping Sun, Jin-Li Wen, Ning Li, Yu-Ming Zhang, Zhi-Gang Yang, Hai-Tao Zhang, Yong Dai
Pages: 2367-2380 Published online on: 15 April 2016
Article
Mouse interleukin-12/FasTI: A novel bi-functional fusion protein for cancer immuno/gene therapy
Xi Yang, Ashlee H. Tietje, Xianzhong Yu, Yanzhang Wei
Pages: 2381-2386 Published online on: 07 April 2016
Article
Receptor-interacting protein-1 promotes the growth and invasion in gastric cancer
Guangwei Zhu, Jianxin Ye, Yongjian Huang, Wei Zheng, Jin Hua, Shugang Yang, Jinfu Zhuang, Jinzhou Wang
Pages: 2387-2398 Published online on: 24 March 2016
Article
Long-term exposure of MCF-12A normal human breast epithelial cells to ethanol induces epithelial mesenchymal transition and oncogenic features
Robert Gelfand, Dolores Vernet, Kevin Bruhn, Jaydutt Vadgama, Nestor F. Gonzalez-Cadavid
Pages: 2399-2414 Published online on: 29 March 2016
Article
Regulation of myo-inositol biosynthesis by p53-ISYNA1 pathway
Tomoyuki Koguchi, Chizu Tanikawa, Jinichi Mori, Yoshiyuki Kojima, Koichi Matsuda
Pages: 2415-2424 Published online on: 24 March 2016
Article
MicroRNA-155 promotes tumor growth of human hepatocellular carcinoma by targeting ARID2
Li Zhang, Wei Wang, Xiaobin Li, Sai He, Jianfeng Yao, Xiaolong Wang, Di Zhang, Xuejun Sun
Pages: 2425-2434 Published online on: 30 March 2016
Article
CLDN6-induced apoptosis via regulating ASK1-p38/JNK signaling in breast cancer MCF-7 cells
Yaxiong Guo, Dongjing Lin, Mingzi Zhang, Xiaowei Zhang, Yanru Li, Ruan Yang, Yan Lu, Xiangshu Jin, Minlan Yang, Miaomiao Wang, Shuai Zhao, Chengshi Quan
Pages: 2435-2444 Published online on: 01 April 2016
Article
Constitutive activation of casein kinase 2 in glioblastomas: Absence of class restriction and broad therapeutic potential
Nadege Dubois, Marie Willems, Minh-Tuan Nguyen-Khac, Jerome Kroonen, Nicolas Goffart, Manuel Deprez, Vincent Bours, Pierre A. Robe
Pages: 2445-2452 Published online on: 18 April 2016
Article
Oridonin induces apoptosis through the mitochondrial pathway in human gastric cancer SGC-7901 cells
Shiyong Gao, Huixin Tan, Nan Zhu, Haiyu Gao, Chunyu Lv, Jian Gang, Yubin Ji
Pages: 2453-2460 Published online on: 07 April 2016
Article
An asymmetrically dimethylarginated nuclear 90 kDa protein (p90aDMA) induced by interleukin (IL)-2, IL-4 or IL-6 in the tumor microenvironment is selectively degraded by autophagy
Lei Sun, Wu-Yan Xia, Shao-Hua Zhao, Ning Liu, Shan-Shan Liu, Peng Xiu, Lin-Feng Li, Xue-Lei Cao, Jian-Xin Gao
Pages: 2461-2471 Published online on: 23 March 2016
Article
Optimal sequence of antisense DNA to silence YB-1 in lung cancer by use of a novel polysaccharide drug delivery system
Hiroto Izumi, Shohei Nagao, Shinichi Mochizuki, Nobuaki Fujiwara, Kazuo Sakurai, Yasuo Morimoto
Pages: 2472-2478 Published online on: 23 March 2016
Article
Leptin promotes breast cancer cell migration and invasion via IL-18 expression and secretion
Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Pages: 2479-2487 Published online on: 12 April 2016
Article
Epithelial protein lost in neoplasm-α (EPLIN-α) is a potential prognostic marker for the progression of epithelial ovarian cancer
Rong Liu, Tracey A. Martin, Nicola J. Jordan, Fiona Ruge, Lin Ye, Wen G. Jiang
Pages: 2488-2496 Published online on: 29 March 2016
Article
Specific expression and methylation of SLIT1, SLIT2, SLIT3, and miR-218 in gastric cancer subtypes
Mirang Kim, Jong-Hwan Kim, Su-Jin Baek, Seon-Young Kim, Yong Sung Kim
Pages: 2497-2507 Published online on: 06 April 2016
Article
Downregulation of RSK2 influences the biological activities of human osteosarcoma cells through inactivating AKT/mTOR signaling pathways
Quanhe Qiu, Jing Jiang, Liangbo Lin, Si Cheng, Daqi Xin, Wei Jiang, Jieliang Shen, Zhenming Hu
Pages: 2508-2520 Published online on: 08 April 2016
Article
The effect of sulforaphane on the cell cycle, apoptosis and expression of cyclin D1 and p21 in the A549 non-small cell lung cancer cell line
Agnieszka Żuryń, Anna Litwiniec, Barbara Safiejko-Mroczka, Anna Klimaszewska-Wiśniewska, Maciej Gagat, Adrian Krajewski, Lidia Gackowska, Dariusz Grzanka
Pages: 2521-2533 Published online on: 18 March 2016
Article
Curcumin and epithelial-mesenchymal transition in breast cancer cells transformed by low doses of radiation and estrogen
Marcela Gallardo, Gloria M. Calaf
Pages: 2534-2542 Published online on: 07 April 2016
Article
Microarray expression profile analysis of aberrant long non-coding RNAs in esophageal squamous cell carcinoma
Juan Yao, Jun-Xing Huang, Mei Lin, Zheng-Dong Wu, Hong Yu, Peng-Cheng Wang, Jun Ye, Ping Chen, Jing Wu, Guo-Jun Zhao
Pages: 2543-2557 Published online on: 24 March 2016
Article
Autophagy inhibition facilitates erlotinib cytotoxicity in lung cancer cells through modulation of endoplasmic reticulum stress
Zhongliang Wang, Tingting Du, Xiaorong Dong, Zhenyu Li, Gang Wu, Ruiguang Zhang
Pages: 2558-2566 Published online on: 01 April 2016
Article
Exosome-shuttling microRNA-21 promotes cell migration and invasion-targeting PDCD4 in esophageal cancer
Juan Liao, Ran Liu, Ya-Juan Shi, Li-Hong Yin, Yue-Pu Pu
Pages: 2567-2579 Published online on: 24 March 2016
Article
EIF3D silencing suppresses renal cell carcinoma tumorigenesis via inducing G2/M arrest through downregulation of Cyclin B1/CDK1 signaling
Xiu-Wu Pan, Lu Chen, Yi Hong, Dan-Feng Xu, Xi Liu, Lin Li, Yi Huang, Li-Ming Cui, Si-Shun Gan, Qi-Wei Yang, Hai Huang, Fa-Jun Qu, Jian-Qing Ye, Lin-Hui Wang, Xin-Gang Cui
Pages: 2580-2590 Published online on: 28 March 2016
Article
Histone deacetylase inhibitor-induced cell death in bladder cancer is associated with chromatin modification and modifying protein expression: A proteomic approach
Qingdi Quentin Li, Jian-Jiang Hao, Zheng Zhang, Iawen Hsu, Yi Liu, Zhen Tao, Keidren Lewi, Adam R. Metwalli, Piyush K. Agarwal
Pages: 2591-2607 Published online on: 07 April 2016
Article
Oridonin inhibits gefitinib-resistant lung cancer cells by suppressing EGFR/ERK/MMP-12 and CIP2A/Akt signaling pathways
Xiangling Xiao, Zhongwei He, Wei Cao, Fen Cai, Liang Zhang, Qiuyue Huang, Chunsheng Fan, Chao Duan, Xiaobo Wang, Jiu Wang, Ying Liu
Pages: 2608-2618 Published online on: 15 April 2016
Article
Interaction between angiotensin II and relaxin 2 in the progress of growth and spread of prostate cancer cells
Kamila Domińska, Tomasz Ochędalski, Karolina Kowalska, Zuzanna Elżbieta Matysiak‑Burzyńska, Elżbieta Płuciennik, Agnieszka Wanda Piastowska-Ciesielska
Pages: 2619-2628 Published online on: 24 March 2016
Article
Antiproliferative effects on colon adenocarcinoma cells induced by co-administration of vitamin K1 and Lactobacillus rhamnosus GG
Antonella Orlando, Michele Linsalata, Francesco Russo
Pages: 2629-2638 Published online on: 29 March 2016
Article
Inhibitory role of TRIP-Br1 oncoprotein in hypoxia-induced apoptosis in breast cancer cell lines
Chengping Li, Samil Jung, Young Yang, Keun-Il Kim, Jong-Seok Lim, Chung-Il Cheon, Myeong-Sok Lee
Pages: 2639-2646 Published online on: 24 March 2016
Article
Knockdown of WAVE1 enhances apoptosis of leukemia cells by downregulating autophagy
Zhaoxia Zhang, Benqing Wu, Wenwen Chai, Lizhi Cao, Yangping Wang, Yan Yu, Liangchun Yang
Pages: 2647-2656 Published online on: 18 March 2016
Article
Theaflavin-3, 3'-digallate induces apoptosis and G2 cell cycle arrest through the Akt/MDM2/p53 pathway in cisplatin-resistant ovarian cancer A2780/CP70 cells
Youying Tu, Eunhye Kim, Ying Gao, Gary O. Rankin, Bo Li, Yi Charlie Chen
Pages: 2657-2665 Published online on: 06 April 2016
Article
Apoptotic effect of noscapine in breast cancer cell lines
Edwin O. Quisbert-Valenzuela, Gloria M. Calaf
Pages: 2666-2674 Published online on: 07 April 2016
Article
Overexpression of long non-coding RNA-CTD903 inhibits colorectal cancer invasion and migration by repressing Wnt/β-catenin signaling and predicts favorable prognosis
Zixu Yuan, Xihu Yu, Beibei Ni, Daici Chen, Zihuan Yang, Jintuan Huang, Jianping Wang, Dianke Chen, Lei Wang
Pages: 2675-2685 Published online on: 21 March 2016
Article
Salinomycin causes migration and invasion of human fibrosarcoma cells by inducing MMP-2 expression via PI3-kinase, ERK-1/2 and p38 kinase pathways
Seon-Mi Yu, Song Ja Kim
Pages: 2686-2692 Published online on: 22 March 2016
Article
Tissue microRNAs as predictive markers for gastric cancer patients undergoing palliative chemotherapy
David Smid, Vlastimil Kulda, Kristyna Srbecka, Dasa Kubackova, Jan Dolezal, Ondrej Daum, Radek Kucera, Ondrej Topolcan, Vladislav Treska, Tomas Skalicky, Martin Pesta
Pages: 2693-2703 Published online on: 12 April 2016
Article
Mangiferin enhances the sensitivity of human multiple myeloma cells to anticancer drugs through suppression of the nuclear factor κB pathway
Tomoya Takeda, Masanobu Tsubaki, Toshiki Kino, Ayako Kawamura, Shota Isoyama, Tatsuki Itoh, Motohiro Imano, Genzoh Tanabe, Osamu Muraoka, Hideaki Matsuda, Takao Satou, Shozo Nishida
Pages: 2704-2712 Published online on: 01 April 2016
Article
Invasion and increased expression of S100A4 and CYR61 in mesenchymal transformed breast cancer cells is downregulated by GnRH
Carsten Gründker, Gerd Bauerschmitz, Antje Schubert, Günter Emons
Pages: 2713-2721 Published online on: 18 April 2016
Correction