Journal Articles
Article
Clinical significance of wall invasion pattern of subserosa-invasive gallbladder carcinoma
Ken-Ichi Okada, Hiroshi Kijima, Toshihide Imaizumi, Kenichi Hirabayashi, Masahiro Matsuyama, Naoki Yazawa, Shoichi Dowaki, Kosuke Tobita, Yasuo Ohtani, Makiko Tanaka, Sadaki Inokuchi, Hiroyasu Makuuchi
Pages: 1531-1536 Published online on: 10 August 2012
Article
Relationship of lower uterine segment cancer with Lynch syndrome: A novel case with an hMLH1 germline mutation
Kenta Masuda, Kouji Banno, Akira Hirasawa, Megumi Yanokura, Kosuke Tsuji, Yusuke Kobayashi, Iori Kisu, Arisa Ueki, Hiroyuki Nomura, Eiichiro Tominaga, Nobuyuki Susumu, Daisuke Aoki
Pages: 1537-1543 Published online on: 31 August 2012
Article
Thyroid transcription factor 1 represses the expression of Ki-67 and induces apoptosis in non-small cell lung cancer
Yun-Fen Zu, Xi-Cai Wang, Yan Chen, Ji-Ying Wang, Xin Liu, Xin Li, Cheng-Wen Li, Yu-Cheng Xie, Yan Luo, Xie-Qin Shang, Jing Guo
Pages: 1544-1550 Published online on: 31 August 2012
Article
Exosomes secreted from human colorectal cancer cell lines contain mRNAs, microRNAs and natural antisense RNAs, that can transfer into the human hepatoma HepG2 and lung cancer A549 cell lines
Mitsuru Chiba, Misako Kimura, Saya Asari
Pages: 1551-1558 Published online on: 10 August 2012
Article
Phosphatidylinositol-3-kinase α catalytic subunit gene somatic mutations in bronchopulmonary neuroendocrine tumours
Alessandra Capodanno, Laura Boldrini, Greta Alì, Serena Pelliccioni, Alfredo Mussi, Gabriella Fontanini
Pages: 1559-1566 Published online on: 04 September 2012
Article
siRNA-mediated silencing of integrin β3 expression inhibits the metastatic potential of B16 melanoma cells
Anna Nasulewicz-Goldeman, Barbara Uszczyńska, Katarzyna Szczaurska-Nowak, Joanna Wietrzyk
Pages: 1567-1573 Published online on: 10 August 2012
Article
Downregulation of indoleamine-2,3-dioxygenase in cervical cancer cells suppresses tumor growth by promoting natural killer cell accumulation
Naoto Sato, Yasushi Saga, Hiroaki Mizukami, Dongdong Wang, Suzuyo Takahashi, Hiroaki Nonaka, Hiroyuki Fujiwara, Yuji Takei, Shizuo Machida, Osamu Takikawa, Keiya Ozawa, Mitsuaki Suzuki
Pages: 1574-1578 Published online on: 23 August 2012
Article
The prognostic value of KRAS mutations in patients with colorectal cancer
Yasuhiro Inoue, Susumu Saigusa, Takashi Iwata, Yoshinaga Okugawa, Yuji Toiyama, Koji Tanaka, Keiichi Uchida, Yasuhiko Mohri, Masato Kusunoki
Pages: 1579-1584 Published online on: 21 August 2012
Article
Downregulation of matrix metalloproteinase-9 mRNA by valproic acid plays a role in inhibiting the shedding of MHC class I-related molecules A and B on the surface of human osteosarcoma cells
Koji Yamanegi, Junko Yamane, Kenta Kobayashi, Hideki Ohyama, Keiji Nakasho, Naoko Yamada, Masaki Hata, Satoru Fukunaga, Hiroyuki Futani, Haruki Okamura, Nobuyuki Terada
Pages: 1585-1590 Published online on: 22 August 2012
Article
Comparison of cellular lethality in DNA repair-proficient or -deficient cell lines resulting from exposure to 70 MeV/n protons or 290 MeV/n carbon ions
Stefan C. Genet, Junko Maeda, Hiroshi Fujisawa, Charles R. Yurkon, Yoshihiro Fujii, Ashley M. Romero, Paula C. Genik, Akira Fujimori, Hisashi Kitamura, Takamitsu A. Kato
Pages: 1591-1596 Published online on: 22 August 2012
Article
Dextran sulfate sodium administered orally is depolymerized in the stomach and induces cell cycle arrest plus apoptosis in the colon in early mouse colitis
Yoshio Araki, Tadao Bamba, Ken-Ichi Mukaisho, Osamu Kanauchi, Hiromitsu Ban, Shigeki Bamba, Akira Andoh, Yoshihide Fujiyama, Takanori Hattori, Hiroyuki Sugihara
Pages: 1597-1605 Published online on: 10 August 2012
Article
Diagnostic accuracy of fine-needle aspiration cytology of the breast in Japan: Report from the Working Group on the Accuracy of Breast Fine-Needle Aspiration Cytology of the Japanese Society of Clinical Cytology
Rin Yamaguchi, Shin-Ιchi Tsuchiya, Takashi Koshikawa, Akinori Ishihara, Shinobu Masuda, Ichiro Maeda, Masafumi Takimoto, Masashi Kawamoto, Haruaki Satoh, Michihiko Narita, Hitoshi Itoh, Takashi Kitamura, Yoshiko Tsuda, Naoki Ogane, Eiji Abe, Katsuhide Ikeda, Takeshi Nakamura, Harumi Kamaguchi, Yoshiro Tokoro
Pages: 1606-1612 Published online on: 03 September 2012
Article
Simultaneous knockdown of APRIL via multiple shRNAs reduces the malignancy of SW480 cells
Haiquan Li, Keke Shao, Jingchun Wang, Guihua Wang, Jin Xu, Jinde Cao, Shaoqing Ju, Huimin Wang
Pages: 1613-1618 Published online on: 22 August 2012
Article
Increased Pontin expression is a potential predictor for outcome in sporadic colorectal carcinoma
Johannes C. Lauscher, Sefer Elezkurtaj, Sonja Dullat, Sybille Lipka, Jörn Gröne, Heinz J. Buhr, Otmar Huber, Martin Kruschewski
Pages: 1619-1624 Published online on: 10 August 2012
Article
Non-muscle myosin II is an independent predictor of overall survival for cystectomy candidates with early-stage bladder cancer
Dan Xiong, Yun-Lin Ye, Ming-Kun Chen, Zi-Ke Qin, Man-Zhi Li, Hua Zhang, Li-Hua Xu, Zhen-Zhou Xu, Mu-Sheng Zeng
Pages: 1625-1632 Published online on: 10 August 2012
Article
Aquaporin-4 upregulated expression in glioma tissue is a reaction to glioma-associated edema induced by vascular endothelial growth factor
Lijuan Yang, Xingfu Wang, Shiming Zhen, Sheng Zhang, Dezhi Kang, Zhixiong Lin
Pages: 1633-1638 Published online on: 21 August 2012
Article
IDH1 mutation of gliomas with long-term survival analysis
Jae Kyung Myung, Hwa Jin Cho, Chul-Kee Park, Seung-Ki Kim, Ji Hoon Phi, Sung-Hye Park
Pages: 1639-1644 Published online on: 24 August 2012
Article
Preclinical biodistribution and safety study of reduced expression in immortalized cells/Dickkopf-3-encoding adenoviral vector for prostate cancer gene therapy
Morito Sugimoto, Masami Watanabe, Haruki Kaku, Shun-Ai Li, Hirofumi Noguchi, Hideo Ueki, Masakiyo Sakaguchi, Nam-Ho Huh, Yasutomo Nasu, Hiromi Kumon
Pages: 1645-1652 Published online on: 30 August 2012
Article
Hepatitis B virus X protein plays an important role in gastric ulcers
Peng-Tao Guo, Dong Yang, Zhe Sun, Hui-Mian Xu
Pages: 1653-1658 Published online on: 03 September 2012
Article
Chemokine receptor 7 via proline-rich tyrosine kinase-2 upregulates the chemotaxis and migration ability of squamous cell carcinoma of the head and neck
Liangliang Yang, Fayu Liu, Zhongfei Xu, Nan Guo, Xiaojiao Zheng, Changfu Sun
Pages: 1659-1664 Published online on: 23 August 2012
Article
Enhanced proliferation of human hepatoma cells by PAR-2 agonists via the ERK/AP-1 pathway
Liqun Xie, Yanmin Zheng, Xuan Li, Junyan Zhao, Xiaoyi Chen, Li Chen, Jing Zhou, Ou Hai, Fei Li
Pages: 1665-1672 Published online on: 31 August 2012
Article
GFP/HPV-16E6 fusion protein induces apoptosis in MCF-7 and 293T cells using a transient expression system
Ge Zhang, Yan Liu, Liwei Yu, Lina Sun
Pages: 1673-1680 Published online on: 22 August 2012
Article
Tetrandrine enhances cytotoxicity of cisplatin in human drug-resistant esophageal squamous carcinoma cells by inhibition of multidrug resistance-associated protein 1
Tian Hu Wang, Jing Yuan Wan, Xia Gong, Hong Zhong Li, Yuan Cheng
Pages: 1681-1686 Published online on: 30 August 2012
Article
Lentivirus-mediated siRNA targeting VEGF inhibits gastric cancer growth in vivo
Peng Sun, Hong Yu, Wen-Qing Zhang, Ming Hu, Rui Lv
Pages: 1687-1692 Published online on: 10 August 2012
Article
The cyclooxygenase-2 inhibitor NS-398 inhibits proliferation and induces apoptosis in human osteosarcoma cells via downregulation of the survivin pathway
Da-Peng Duan, Xiao-Qian Dang, Kun-Zheng Wang, Yong-Ping Wang, Hui Zhang, Wu-Lin You
Pages: 1693-1700 Published online on: 24 August 2012
Article
Expression of endothelial cell-specific molecule-1 regulated by hypoxia inducible factor-1α in human colon carcinoma: Impact of ESM-1 on prognosis and its correlation with clinicopathological features
Joo Heon Kim, Mee Young Park, Chang Nam Kim, Kyo Hyun Kim, Ho Bum Kang, Kwang Dong Kim, Jae Wha Kim
Pages: 1701-1708 Published online on: 03 September 2012
Article
ADAM10 overexpression in human non-small cell lung cancer correlates with cell migration and invasion through the activation of the Notch1 signaling pathway
Jianli Guo, Lei He, Ping Yuan, Peng Wang, Yanjun Lu, Fangli Tong, Yu Wang, Yanhua Yin, Jun Tian, Jun Sun
Pages: 1709-1718 Published online on: 30 August 2012
Article
Induction of apoptosis by 7-piperazinethylchrysin in HCT-116 human colon cancer cells
Jie Ren, Hong Cheng, Wen Qun Xin, Xin Chen, Kun Hu
Pages: 1719-1726 Published online on: 04 September 2012
Article
Establishment of a human lung cancer cell line with high metastatic potential to multiple organs: gene expression associated with metastatic potential in human lung cancer
Tetsuhiro Nakano, Kimihiro Shimizu, Osamu Kawashima, Mitsuhiro Kamiyoshihara, Seiichi Kakegawa, Masayuki Sugano, Takashi Ibe, Toshiteru Nagashima, Kyoichi Kaira, Noriaki Sunaga, Youichi Ohtaki, Jun Atsumi, Izumi Takeyoshi
Pages: 1727-1735 Published online on: 21 August 2012
Article
Molecular imaging and therapeutic efficacy of 188Re-(DXR)-liposome-BBN in AR42J pancreatic tumor-bearing mice
Ya-Jen Chang, Chia-Yu Yu, Chin-Wei Hsu, Wan-Chi Lee, Su-Jung Chen, Chih-Hsien Chang, Te-Wei Lee
Pages: 1736-1742 Published online on: 22 August 2012
Article
In vivo distribution and antitumor effect of infused immune cells in a gastric cancer model
Xiaohui Du, Runsen Jin, Ning Ning, Li Li, Quansheng Wang, Wentao Liang, Juchao Liu, Yingxin Xu
Pages: 1743-1749 Published online on: 03 September 2012
Article
The distribution of human papillomavirus in tissues from patients with head and neck squamous cell carcinoma
Wei Wei, Qi Shi, Fei Guo, Bao-Yun Zhang, Cao Chen, Nai-Song Zhang, Xiao-Ping Dong
Pages: 1750-1756 Published online on: 24 August 2012
Article
Hexane extracts of garlic cloves induce apoptosis through the generation of reactive oxygen species in Hep3B human hepatocarcinoma cells
Hye Jeong Kim, Min Ho Han, Gi Young Kim, Young-Whan Choi, Yung Hyun Choi
Pages: 1757-1763 Published online on: 23 August 2012
Article
miR-15a and miR-16-1 downregulate CCND1 and induce apoptosis and cell cycle arrest in osteosarcoma
Cheng-Kui Cai, Guang-Yi Zhao, Li-Ying Tian, Lie Liu, Kang Yan, Yun-Lei Ma, Zhen-Wei Ji, Xiao-Xiang Li, Kang Han, Jie Gao, Xiu-Chun Qiu, Qing-Yu Fan, Tong-Tao Yang, Bao-An Ma
Pages: 1764-1770 Published online on: 24 August 2012
Article
miR-92a is a critical regulator of the apoptosis pathway in glioblastoma with inverse expression of BCL2L11 Corrigendum in /or/32/3/1319
Huanjiang Niu, Kun Wang, Anling Zhang, Shuxu Yang, Zhengfei Song, Wei Wang, Cong Qian, Xinwei Li, Yinxin Zhu, Yirong Wang
Pages: 1771-1777 Published online on: 10 August 2012
Article
Lentivirus-mediated short-hairpin RNA targeting IGF-1R inhibits growth and lymphangiogenesis in breast cancer
Yaning Chen, Chenfang Zhu, Zhiyou Peng, Yalei Dai, Yan Gu
Pages: 1778-1784 Published online on: 10 August 2012
Article
Frequent silencing of protocadherin 8 by promoter methylation, a candidate tumor suppressor for human gastric cancer
Danjie Zhang, Wei Zhao, Xinhua Liao, Tieqiang Bi, Haijun Li, Xiangming Che
Pages: 1785-1791 Published online on: 30 August 2012
Article
Identification of the cancer/testis antigens AKAP3 and CTp11 by SEREX in hepatocellular carcinoma
Myung-Ha Song, Kyung-Un Choi, Dong-Hoon Shin, Chang-Hun Lee, Sang-Yull Lee
Pages: 1792-1798 Published online on: 30 August 2012
Article
Epigallocatechin gallate sensitizes CAL-27 human oral squamous cell carcinoma cells to the anti-metastatic effects of gefitinib (Iressa) via synergistic suppression of epidermal growth factor receptor and matrix metalloproteinase-2
Chia-Ming Chang, Pei-Ying Chang, Ming-Gene Tu, Chi-Cheng Lu, Sheng-Chu Kuo, Sakae Amagaya, Chao-Ying Lee, Hui-Yu Jao, Michael Yuanchien Chen, Jai-Sing Yang
Pages: 1799-1807 Published online on: 24 August 2012
Article
Enhanced membrane-type 1 matrix metalloproteinase expression by hyaluronan oligosaccharides in breast cancer cells facilitates CD44 cleavage and tumor cell migration
Chang-I Kung, Cheng-Yi Chen, Chih-Chang Yang, Cheng-Yu Lin, Tien-Hua Chen, Hwai-Shi Wang
Pages: 1808-1814 Published online on: 24 August 2012
Article
Direct serum and tissue assay for EGFR mutation in non-small cell lung cancer by high-resolution melting analysis
Chengjin Hu, Xiaolei Liu, Yingjian Chen, Xiaoming Sun, Yanwen Gong, Ming Geng, Liquan Bi
Pages: 1815-1821 Published online on: 23 August 2012
Article
In vivo real-time imaging of chemotherapy response on the liver metastatic tumor microenvironment using multiphoton microscopy
Koji Tanaka, Masato Okigami, Yuji Toiyama, Yuki Morimoto, Kohei Matsushita, Mikio Kawamura, Kiyoshi Hashimoto, Susumu Saigusa, Yoshinaga Okugawa, Yasuhiro Inoue, Keiichi Uchida, Toshimitsu Araki, Yasuhiko Mohri, Akira Mizoguchi, Masato Kusunoki
Pages: 1822-1830 Published online on: 23 August 2012
Article
miR-143 and miR-145 inhibit stem cell characteristics of PC-3 prostate cancer cells
Shuai Huang, Wei Guo, Yubo Tang, Dong Ren, Xuenong Zou, Xinsheng Peng
Pages: 1831-1837 Published online on: 04 September 2012
Article
Changes in expression of human serine protease HtrA1, HtrA2 and HtrA3 genes in benign and malignant thyroid tumors
Dorota Zurawa-Janicka, Jarosław Kobiela, Natalia Galczynska, Tomasz Stefaniak, Barbara Lipinska, Andrzej Lachinski, Joanna Skorko-Glonek, Joanna Narkiewicz, Monika Proczko-Markuszewska, Zbigniew Sledzinski
Pages: 1838-1844 Published online on: 23 August 2012
Article
Proteomic differential display identifies upregulated vinculin as a possible biomarker of pancreatic cancer
Yufeng Wang, Yasuhiro Kuramitsu, Tomio Ueno, Nobuaki Suzuki, Shigefumi Yoshino, Norio Iizuka, Xiulian Zhang, Junko Akada, Masaaki Oka, Kazuyuki Nakamura
Pages: 1845-1850 Published online on: 30 August 2012
Article
Sulforaphane synergistically enhances the cytotoxicity of arsenic trioxide in multiple myeloma cells via stress-mediated pathways
Nicole A. Doudican, Shih Ya Wen, Amitabha Mazumder, Seth J. Orlow
Pages: 1851-1858 Published online on: 22 August 2012
Article
Polymorphisms in base excision repair genes and thyroid cancer risk
Luís S. Santos, Sandra C. Branco, Susana N. Silva, Ana Paula Azevedo, Octávia M. Gil, Isabel Manita, Teresa C. Ferreira, Edward Limbert, José Rueff, Jorge F. Gaspar
Pages: 1859-1868 Published online on: 22 August 2012
Article
Suppression of tunicamycin-induced CD44v6 ectodomain shedding and apoptosis is correlated with temporal expression patterns of active ADAM10, MMP-9 and MMP-13 proteins in Caki-2 renal carcinoma cells
Yeoun-Hee Kim, Jae-Chang Jung
Pages: 1869-1874 Published online on: 23 August 2012
Article
Granulocyte colony-stimulating factor potentiates differentiation induction by all-trans retinoic acid and arsenic trioxide and enhances arsenic uptake in the acute promyelocytic leukemia cell line HT93A
Noriyoshi Iriyama, Bo Yuan, Yoshihiro Hatta, Akira Horikoshi, Yuta Yoshino, Hiroo Toyoda, Shin Aizawa, Jin Takeuchi
Pages: 1875-1882 Published online on: 31 August 2012
Article
Apoptosis triggered by vitexin in U937 human leukemia cells via a mitochondrial signaling pathway
Chao-Ying Lee, Yung-Shin Chien, Tai-Hui Chiu, Wen-Wen Huang, Chi-Cheng Lu, Jo-Hua Chiang, Jai-Sing Yang
Pages: 1883-1888 Published online on: 30 August 2012
Article
Yes is a central mediator of cell growth in malignant mesothelioma cells
Ayami Sato, Miki Sekine, Nantiga Virgona, Masako Ota, Tomohiro Yano
Pages: 1889-1893 Published online on: 03 September 2012
Article
Radiosensitizing effects of arsenic trioxide on MCF-7 human breast cancer cells exposed to 89strontium chloride
Hengchao Liu, Xinquan Tao, Fang Ma, Jun Qiu, Cuiping Wu, Mingming Wang
Pages: 1894-1902 Published online on: 22 August 2012
Article
17AEP-GA, an HSP90 antagonist, is a potent inhibitor of glioblastoma cell proliferation, survival, migration and invasion
Katarzyna Miekus, Jacek Kijowski, Małgorzata Sekuła, Marcin Majka
Pages: 1903-1903 Published online on: 27 August 2012
Article
Dioscin sensitizes cells to TRAIL-induced apoptosis through downregulation of c-FLIP and Bcl-2
Yong-Sik Kim, Eun-Ae Kim, Kyu-Gun Park, Sung-Jun Lee, Mi-Sun Kim, Ho-Yong Sohn, Tae-Jin Lee
Pages: 1910-1916 Published online on: 09 August 2012
Article
Protease-activated receptor-2 induces expression of vascular endothelial growth factor and cyclooxygenase-2 via the mitogen-activated protein kinase pathway in gastric cancer cells
Cheng Zhang, Guang-Rong Gao, Chen-Guang Lv, Boa-Lei Zhang, Zhi-Li Zhang, Xue-Feng Zhang
Pages: 1917-1923 Published online on: 30 August 2012
Article
