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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August-2016 Volume 38 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Synthesis of and in vitro and in vivo evaluation of a novel TGF-β1-SF-CS three-dimensional scaffold for bone tissue engineering

Shuang Tong, Da-Peng Xu, Zi-Mei Liu, Yang Du, Xu-Kai Wang
Pages: 367-380
Published online on: 21 June 2016

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Article Open Access

CRM-1 knockdown inhibits extrahepatic cholangiocarcinoma tumor growth by blocking the nuclear export of p27Kip1

Jian Luo, Yongjun Chen, Qiang Li, Bing Wang, Yanqiong Zhou, Hongzhen Lan
Pages: 381-390
Published online on: 07 June 2016

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Article Open Access

TGF-β1, in association with the increased expression of connective tissue growth factor, induce the hypertrophy of the ligamentum flavum through the p38 MAPK pathway

Yan-Lin Cao, Yang Duan, Li-Xin Zhu, Ye-Nan Zhan, Shao-Xiong Min, An-Min Jin
Pages: 391-398
Published online on: 08 June 2016

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Article Open Access

Nuclear import of prototype foamy virus transactivator Bel1 is mediated by KPNA1, KPNA6 and KPNA7 Retraction in /10.3892/ijmm.2017.2860

Jihui Duan, Zhiqin Tang, Hong Mu, Guojun Zhang
Pages: 399-406
Published online on: 09 June 2016

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Article Open Access

Silencing of ILK attenuates the abnormal proliferation and migration of human Tenon's capsule fibroblasts induced by TGF-β2

Yao Xing, Lijun Cui, Qianyan Kang
Pages: 407-416
Published online on: 16 June 2016

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Article Open Access

NF-κB signaling maintains the survival of cadmium-exposed human renal glomerular endothelial cells

Hongyan Zhang, Liqun Li, Yifan Wang, Fengyun Dong, Xiaocui Chen, Fuhong Liu, Dongmei Xu, Fan Yi, Carolyn M. Kapron, Ju Liu
Pages: 417-422
Published online on: 14 June 2016

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Article Open Access

Differential gene expression in mouse spermatogonial stem cells and embryonic stem cells

Yinshan Bai, Meiying Feng, Shanshan Liu, Hengxi Wei, Li Li, Xianwei Zhang, Chao Shen, Shouquan Zhang, Ningfang Ma
Pages: 423-432
Published online on: 28 June 2016

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Article Open Access

Altered expression of mir-222 and mir-25 influences diverse gene expression changes in transformed normal and anaplastic thyroid cells, and impacts on MEK and TRAIL protein expression

Sinéad T. Aherne, Paul Smyth, Michael Freeley, Leila Smith, Cathy Spillane, John O'Leary, Orla Sheils
Pages: 433-445
Published online on: 22 June 2016

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Article Open Access

Regulation of CBL and ESR1 expression by microRNA-22‑3p, 513a-5p and 625-5p may impact the pathogenesis of dust mite-induced pediatric asthma

Xiaoyan Dong, Miao Xu, Zhaorui Ren, Jianlei Gu, Min Lu, Quan Lu, Nanbert Zhong
Pages: 446-456
Published online on: 09 June 2016

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Article Open Access

Enhanced hepatic differentiation of rat bone marrow-derived mesenchymal stem cells in spheroidal aggregate culture on a decellularized liver scaffold

Ji Bao, Qiong Wu, Yujia Wang, Yi Li, Li Li, Fei Chen, Xiujuan Wu, Mingjun Xie, Hong Bu
Pages: 457-465
Published online on: 14 June 2016

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Article Open Access

Bioinformatics analysis of differentially expressed pathways related to the metastatic characteristics of osteosarcoma

Wei Sun, Xiaojun Ma, Jiakang Shen, Fei Yin, Chongren Wang, Zhengdong Cai
Pages: 466-474
Published online on: 27 June 2016

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Article Open Access

Cooperative effects of hepatitis B virus and TNF may play important roles in the activation of metabolic pathways through the activation of NF-κB

Shuang Wu, Tatsuo Kanda, Shingo Nakamoto, Xia Jiang, Masato Nakamura, Reina Sasaki, Yuki Haga, Hiroshi Shirasawa, Osamu Yokosuka
Pages: 475-481
Published online on: 16 June 2016

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Article

Amelioration of an LPS-induced inflammatory response using a methanolic extract of Lagerstroemia ovalifolia to suppress the activation of NF-κB in RAW264.7 macrophages

Ji-Won Park, Ok-Kyoung Kwon, Prasetyawan Yuniato, Bambang Marwoto, Joongku Lee, Sei-Ryang Oh, Jae-Hong Kim, Kyung-Seop Ahn
Pages: 482-490
Published online on: 16 June 2016

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Article

Aqueous extract of pomegranate seed attenuates glucocorticoid-induced bone loss and hypercalciuria in mice: A comparative study with alendronate

Yan Zhang, Jin Shao, Zhi Wang, Tieyi Yang, Shuyi Liu, Yue Liu, Xinbing Fan, Weiguang Ye
Pages: 491-498
Published online on: 03 June 2016

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Article

MicroRNA-17 induces epithelial-mesenchymal transition consistent with the cancer stem cell phenotype by regulating CYP7B1 expression in colon cancer

Xiang‑Peng Xi, Jing Zhuang, Mu‑Jian Teng, Li‑Jian Xia, Ming‑Yu Yang, Qing‑Gen Liu, Jing‑Bo Chen
Pages: 499-506
Published online on: 06 June 2016

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Article

MicroRNA-223 affects IL-6 secretion in mast cells via the IGF1R/PI3K signaling pathway

Qianyuan Yang, Hong Xu, Jin Yang, Yao Zhou, Deyu Zhao, Feng Liu
Pages: 507-512
Published online on: 21 June 2016

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Article

Hepatitis B virus X protein promotes renal epithelial-mesenchymal transition in human renal proximal tubule epithelial cells through the activation of NF-κB

Mei Li, Liping Hu, Fengxin Zhu, Zhangmei Zhou, Jianwei Tian, Jun Ai
Pages: 513-520
Published online on: 10 June 2016

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Article

p-CREB-1 promotes hepatic fibrosis through the transactivation of transforming growth factor-β1 expression in rats

Pei Wang, Liang Deng, Chunbo Zhuang, Chunwei Cheng, Keshu Xu
Pages: 521-528
Published online on: 08 June 2016

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Article

Identification of pterygium-related long non-coding RNAs and expression profiling by microarray analysis

Jin Liu, Xiangya Ding, Li Yuan, Xiaojun Zhang
Pages: 529-536
Published online on: 14 June 2016

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Article

Notoginsenoside R1 significantly promotes in vitro osteoblastogenesis

Yi Liu, Zhen Lin, Jing Guo, Gaoli Xu, Ye Li, Taotao Xu, Huiqing Lv, Jianzhi Chen, Gang Wu
Pages: 537-544
Published online on: 21 June 2016

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Article

Regulation of vascular endothelial growth factor-C by tumor necrosis factor-α in the conjunctiva and pterygium

Yoko Dong, Satoru Kase, Zhenyu Dong, Junichi Fukuhara, Yoshiaki Tagawa, Erdal Tan Ishizuka, Miyuki Murata, Yasuhiro Shinmei, Takeshi Ohguchi, Atsuhiro Kanda, Kousuke Noda, Susumu Ishida
Pages: 545-550
Published online on: 16 June 2016

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Article

Astragalus polysaccharide induces the apoptosis of human hepatocellular carcinoma cells by decreasing the expression of Notch1

Wen-Hai Huang, Wei-Rong Liao, Rong-Xun Sun
Pages: 551-557
Published online on: 09 June 2016

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Article

Homooligomerization of ABCA3 and its functional significance

Sabrina Frixel, Amelie S. Lotz-Havla, Sunčana Kern, Eva Kaltenborn, Thomas Wittmann, Søren W. Gersting, Ania C. Muntau, Ralf Zarbock, Matthias Griese
Pages: 558-566
Published online on: 21 June 2016

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Article

Neuroprotective effects of syringic acid against OGD/R-induced injury in cultured hippocampal neuronal cells

Yidong Cao, Liang Zhang, Shukai Sun, Zhenheng Yi, Xue Jiang, Dong Jia
Pages: 567-573
Published online on: 03 June 2016

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Article Open Access

Ethanol extracts of chickpeas alter the total lipid content and expression levels of genes related to fatty acid metabolism in mouse 3T3-L1 adipocytes

Shigeo Shinohara, Yuanjun Gu, Ying Yang, Yasuo Furuta, Masahiko Tanaka, Xiaohua Yue, Weiqing Wang, Masaru Kitano, Hiroshi Kimura
Pages: 574-584
Published online on: 24 June 2016

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Article

Increased RANKL expression in peripheral T cells is associated with decreased bone mineral density in patients with COPD

Ying Chen, Peng Bai, Lili Liu, Junyan Han, Hui Zeng, Yongchang Sun
Pages: 585-593
Published online on: 08 June 2016

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Article

Mechanical strain promotes osteoblastic differentiation through integrin-β1-mediated β-catenin signaling

Yuxian Yan, Haoyang Sun, Yuanwei Gong, Zhixiong Yan, Xizheng Zhang, Yong Guo, Yang Wang
Pages: 594-600
Published online on: 10 June 2016

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Article

Transgenic overexpression of transient receptor potential vanilloid subtype 1 attenuates isoproterenol-induced myocardial fibrosis in mice

Qiang Wang, Yunrong Zhang, De Li, Yan Zhang, Bing Tang, Gang Li, Yongjian Yang, Dachun Yang
Pages: 601-609
Published online on: 16 June 2016

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Article

Ethanol extract of Lithospermum erythrorhizon Sieb. et Zucc. promotes osteoblastogenesis through the regulation of Runx2 and Osterix

You Hee Choi, Geum Soog Kim, Jae Ho Choi, Sun Woo Jin, Hyung Gyun Kim, Younho Han, Dae Young Lee, Soo Im Choi, Seung Yu Kim, Young Sup Ahn, Kwang Youl Lee, Hye Gwang Jeong
Pages: 610-618
Published online on: 24 June 2016

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Article

Quercetin inhibits the growth of human gastric cancer stem cells by inducing mitochondrial-dependent apoptosis through the inhibition of PI3K/Akt signaling

Xinsheng Shen, Yaqing Si, Zhao Wang, Jiachen Wang, Yongqiang Guo, Xiefu Zhang
Pages: 619-626
Published online on: 06 June 2016

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Article

Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo

Sungjin Choi, Jeungyeun Youn, Karam Kim, Da Hye Joo, Shanghun Shin, Jeongju Lee, Hyun Kyung Lee, In-Sook An, Seungbin Kwon, Hae Jeong Youn, Kyu Joong Ahn, Sungkwan An, Hwa Jun Cha
Pages: 627-634
Published online on: 06 June 2016

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Article

Effect of tyrosine hydroxylase overexpression in lymphocytes on the differentiation and function of T helper cells

Hui-Wei Huang, Cong Zuo, Xiao Chen, Yu-Ping Peng, Yi-Hua Qiu
Pages: 635-642
Published online on: 14 June 2016

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Article

Visfatin attenuates the ox-LDL-induced senescence of endothelial progenitor cells by upregulating SIRT1 expression through the PI3K/Akt/ERK pathway

Guang-Feng Ming, Yong-Jun Tang, Kai Hu, Yao Chen, Wei-Hua Huang, Jian Xiao
Pages: 643-649
Published online on: 09 June 2016

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Article

Heat shock protein 90 is involved in IL-17-mediated skin inflammation following thermal stimulation

Bo-Kyung Kim, Minhwa Park, Ji-Yon Kim, Kyung-Ho Lee, So-Youn Woo
Pages: 650-658
Published online on: 07 June 2016

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Article

Advanced glycation end products inhibit testosterone secretion by rat Leydig cells by inducing oxidative stress and endoplasmic reticulum stress

Yun-Tao Zhao, Ya-Wei Qi, Chuan-Yin Hu, Shao-Hong Chen, You Liu
Pages: 659-665
Published online on: 16 June 2016

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Article

Pyropia yezoensis glycoprotein promotes the M1 to M2 macrophage phenotypic switch via the STAT3 and STAT6 transcription factors

Jeong-Wook Choi, Mi-Jin Kwon, In-Hye Kim, Young-Min Kim, Min‑Kyeong Lee, Taek-Jeong Nam
Pages: 666-674
Published online on: 24 June 2016

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Correction Open Access

[Corrigendum] Chromatin immunoprecipitation-sequencing predicts p300 binding sites in the MCF7 human breast cancer cell line

Xiemei Wang, Shaolin Li
Pages: 675-675
Published online on: 15 June 2016

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Journal Cover
May-2026 Volume 57 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Macrophage SH3 domain‑containing GRB2‑like protein B1 is required for Rab7‑mediated mitophagy in inflammation during sea water drowning acute lung injury

Hongjuan Ning, Jingyu Deng, Yongheng Gao, Wei Zhang, Jian Chen, Xian Guo, Faguang Jin
Article Number: 138
Published online on: 24 March 2026

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Article Open Access

Deferoxamine mitigates neuronal loss following spinal cord injury via ferroptosis inhibition and Nrf2/HO‑1 pathway activation

Ziqian Ma, Xinwei Zhang, Tao Liu, Yan Zhang, Guanghao Li, Xin Yuan, Benqiang Tang, Hangyi Zhao, Liang Liu, Xueming Chen
Article Number: 137
Published online on: 23 March 2026

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Review Open Access

USP10 deubiquitinase: Physiological function, diseases and therapeutic target (Review)

Linlin Zhang, Huajing Sun, Zifan Wang, Zhimei Wang, Qiang Mu, Yukun Liu
Article Number: 136
Published online on: 23 March 2026

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Article Open Access

Siglec‑15 dysregulation and its therapeutic implications in new‑onset type 1 diabetes 

Heming Guo, Yunwen Tao, Sicheng Li, Ying Gu, Yiting Huang, Chen Fang, Ji Hu
Article Number: 135
Published online on: 20 March 2026

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Article Open Access

ZEB1 maintains mitochondrial fission and macrophage efferocytosis by restraining MFN2, thereby limiting inflammation and improving tendon‑bone healing

Yan Zhao, Yuankai Zhang, Tian Lei, Shangqing Zhang, Kai Nan, Xin Zhang, Li-Hong Fan
Article Number: 134
Published online on: 19 March 2026

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Review Open Access

Targeting pyroptosis in renal fibrosis: From molecular mechanisms to therapeutic horizons (Review)

Yihuai Tian, Quwu Mushuo, Hui Fan, Hongwei Su, Jianchun Li, Qiong Zhang
Article Number: 133
Published online on: 19 March 2026

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Expression of Concern Open Access

[Expression of Concern] Fasudil, a Rho‑associated protein kinase inhibitor, attenuates retinal ischemia and reperfusion injury in rats

Haishan Song, Dianwen Gao
Article Number: 132
Published online on: 18 March 2026

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Review Open Access

Epigenetic regulation in a high-sugar environment (Review)

Huili Zhou, Xinhe Lv, Yu Liang, Dehai Yu, Wanning Wang
Article Number: 131
Published online on: 17 March 2026

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Review Open Access

The roles and heterogeneity of CD8+ T cells in inflammatory bowel disease: A narrative review of insights from single‑cell transcriptomics (Review)

Rui Zhong, Jing Guo, Wujie Ye, Zhihui Deng, Huangan Wu, Qin Qi, Guona Li, Lu Zhu, Yan Huang, Luyi Wu
Article Number: 130
Published online on: 17 March 2026

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Mechanism of action and clinical application of autophagy in multiple sclerosis (Review)

Dongmei Wang, Qizhi Fu, Ying Zhao, Guangda Li, Yongjie Bai, Yang Yang, Hongna Song, Mingwei Wang, Hua Fan
Article Number: 129
Published online on: 17 March 2026

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Expression of Concern Open Access

[Expression of Concern] Insulin‑dependent diabetes mellitus decreases osteoblastogenesis associated with the inhibition of Wnt signaling through increased expression of Sost and Dkk1 and inhibition of Akt activation

Mamiko Hie, Natsumi Iitsuka, Tomoyo Otsuka, Ikuyo Tsukamoto
Article Number: 128
Published online on: 16 March 2026

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Review Open Access

Mechanotransduction and its impact on regenerative medicine in orthopedic rehabilitation (Review)

Baohui Wang, Xueqin Zeng, Huajian Liu, Liang Li, Tao Lei, Yafeng Li, Qing Fang, Yi Cao, Bo Dong
Article Number: 127
Published online on: 13 March 2026

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Article Open Access

4‑Acetylantrocamol LT3 suppresses colorectal cancer growth and metastasis via PI3K/AKT and MAPK pathway modulation

Kuen-Tze Lin, Yu-Chieh Hsieh, Pi-Kai Chang, Chih-Wei Lai, Shih-Yu Lee, I-Chuan Yen
Article Number: 126
Published online on: 13 March 2026

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Review Open Access

Roles of ubiquitin‑specific peptidase 22 in cellular fate: From embryonic survival to tissue repair, inflammation and metabolism (Review)

Jia-Nan Xiang, Chen-Yang Zhou, Yu-Di Zhao, Xiao Xu, Sun-Bin Ling
Article Number: 125
Published online on: 12 March 2026

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Review Open Access

m6A in adipose tissue inflammation: A novel regulator of obesity and metabolic diseases (Review)

Xiaoting Yang, Xiaodan Wang, Haojun Tang, Shuangxi Tu, Kai Yin, Xiao Zhu
Article Number: 124
Published online on: 12 March 2026

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Expression of Concern Open Access

[Expression of Concern] Visfatin/PBEF/Nampt induces EMMPRIN and MMP‑9 production in macrophages via the NAMPT‑MAPK (p38, ERK1/2)‑NF‑κB signaling pathway

Yuqi Fan, Shu Meng, Yue Wang, Jiatian Cao, Changqian Wang
Article Number: 123
Published online on: 12 March 2026

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Article Open Access

IL‑37/IL‑1R8 blocks keratinocyte acantholysis via suppressing ADAM17/EGFR

Fengxia Hu, Wenjing Chen, Qian Wang, Xiaoyu Zhang, Fuyang Xiao, Jinying Zhang, Junqin Liang
Article Number: 122
Published online on: 12 March 2026

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Review Open Access

Reactive oxygen species in fetal growth restriction mechanisms and therapeutic directions (Review)

Di Cheng, Songbin Yang, Cuilan Wang, Kefeng Fan, Fengchun Gao, Qian Sun
Article Number: 121
Published online on: 12 March 2026

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Review Open Access

Research progress on the molecular mechanisms of tanshinone IIA in the treatment of cardiovascular and cerebrovascular diseases (Review)

Wen Pei, Ping Lu, Chenhuan Ding, Ying Li, Yong Li
Article Number: 120
Published online on: 12 March 2026

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Review Open Access

Ferritin in ferroptosis: Implications for neurodegenerative diseases (Review)

Wenjing Chen, Heng Tian, Ran Wei, Xiaomei Chen, Yiwen Jia
Article Number: 119
Published online on: 12 March 2026

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Correction Open Access

[Corrigendum] Ursolic acid protects against cisplatin‑induced ototoxicity by inhibiting oxidative stress and TRPV1‑mediated Ca2+‑signaling  

Yang Di, Tao Xu, Yuan Tian, Tingting Ma, Donghao Qu, Yan Wang, Yuhan Lin, Dongyan Bao, Li Yu, Shuangyue Liu, Aimei Wang
Article Number: 118
Published online on: 09 March 2026

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Article Open Access

HELLS inhibits autophagy‑dependent ferroptosis in nasopharyngeal carcinoma by modulating the Nrf2/HO‑1/GPX4 pathway

Chengxun Jin, Jinqiu Li, Siqi Han, Chaoluomeng Bai, Jingpu Yang, Zonggui Wang
Article Number: 117
Published online on: 09 March 2026

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Expression of Concern Open Access

[Expression of Concern] Inhibitory effect of curcumin on angiogenesis in ectopic endometrium of rats with experimental endometriosis

Ying Zhang, Hong Cao, Yue-Yue Hu, Hua Wang, Chang-Jun Zhang
Article Number: 116
Published online on: 09 March 2026

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Propofol upregulates MFG‑E8 in BV2 cells to inhibit pyroptosis mediated by the NF‑κB/NLRP3 pathway, thereby ameliorating ischemic‑reperfusion neuronal injury

Shewei Guo, Yingwei Zhen, Guosheng Zhou, Zhihua Zhao
Article Number: 115
Published online on: 05 March 2026

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Exosomal circ0000549 promotes MNNG‑induced gastric cancer through miR‑15b‑5p/KIF1B

Zhaofeng Liang, Zihan Gao, Yue Zhang, Jiajia Song, Hui Qian, Xuezhong Xu
Article Number: 114
Published online on: 04 March 2026

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Expression of Concern Open Access

[Expression of Concern] Syringin prevents cardiac hypertrophy induced by pressure overload through the attenuation of autophagy  

Fangfang Li, Ning Zhang, Qingqing Wu, Yuan Yuan, Zheng Yang, Mengqiao Zhou, Jinxiu Zhu, Qizhu Tang
Article Number: 113
Published online on: 04 March 2026

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Review Open Access

Treatment of pulmonary fibrosis: From disease mechanisms to future novel therapies (Review)

Sen Lu, Yunfei Liu, Xiaohua Li, Qipeng Yao
Article Number: 112
Published online on: 03 March 2026

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Review Open Access

Research progress in single‑cell omics technologies for kidney disease (Review)

Jia Xu, Ziwei Chen, Shengyao Li, Xiaoya Wang, Ming Chen
Article Number: 111
Published online on: 03 March 2026

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CLDN7: Epithelial gatekeeper from physiology to pathology‑roles in cancer and epithelial‑related diseases (Review)

Xiuping Lai, Yan Yan, Lu Sun, Zili Lei, Yanhong Yang
Article Number: 110
Published online on: 03 March 2026

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Dynamic regulation and targeted intervention of neutrophils in hepatic ischemia‑reperfusion injury (Review)

Sen Lu, Jiale Tong, Jing Jiang, Qin Zhang, Youjin Huang
Article Number: 109
Published online on: 03 March 2026

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The dual role of the crosstalk between autophagy and ferroptosis in lung cancer treatment: Advances in mechanisms and therapeutic strategies (Review)

Yingying Zhang, Ruxin Shen
Article Number: 108
Published online on: 02 March 2026

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Review Open Access

Mechanistic insights into inflammatory cytokines in adenomyosis‑induced infertility (Review)

Bojiao Yang, Feng Li, Guimao Cao, Mingtu Nuo, Yaxin Shi, Zilu Wang, Jing Jia, Wei Shi, Zhiyong Liu
Article Number: 107
Published online on: 02 March 2026

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Correction Open Access

[Corrigendum] Astragaloside IV promotes the proliferation and migration of osteoblast‑like cells through the hedgehog signaling pathway

Li-Hua Guo, Yu Cao, Run-Tao Zhuang, Yan Han, Jun Li
Article Number: 106
Published online on: 02 March 2026

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June-2026 Volume 57 Issue 6

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Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Astragaloside IV targets TUBB4B to inhibit proliferation and promote apoptosis of pituitary tumor cells via the STMN1/ERK pathway

Jiale Li, Yufei Qu, Wenge Zhang, Zexu Yang, Yangdong Zeng, Jisheng Xu, Kuncen Xie, Qi Liu
Article Number: 151
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Increased expression of heat shock protein 90 under chemical hypoxic conditions protects cardiomyocytes against injury induced by serum and glucose deprivation

Keng Wu, Wenming Xu, Qiong You, Runmin Guo, Jianqiang Feng, Changran Zhang, Wen Wu
Article Number: 150
Published online on: 01 April 2026

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Review Open Access

Animal models accurately representing acute liver failure (Review)

Sang Luo, Fang Wu, Yiran Jin, Xiaofen Huang, Dan Liu, Bingren Tian
Article Number: 149
Published online on: 01 April 2026

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Correction Open Access

[Corrigendum] Influence of aspirin on the CX3CL1/CX3CR1 signaling pathway in acute pulmonary embolism 

Zhirong Zhang, Weiji Yang, Rongbiao Ying, Ying Shi, Huifang Jiang, Danli Cai, Jing Kuang, Ruhui Yang, Lingcong Wang
Article Number: 148
Published online on: 31 March 2026

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Targeting pyroptosis to treat aortic aneurysms: From mechanism to drug discovery (Review)

Jing Mao, Mandi Luo, Lei Ruan, Cuntai Zhang
Article Number: 147
Published online on: 31 March 2026

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Role of aging‑related cytokines in neurodegenerative disease (Review)

Xinke Dai, Xinran Rao, Yuandi Wang, Weijiang Zhao
Article Number: 146
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] DTX3L is upregulated in glioma and is associated with glioma progression

Peng Xu, Xuelei Tao, Chengjin Zhao, Qingfeng Huang, Hao Chang, Na Ban, Yuanqi Bei, Xiaojie Xia, Chaoyan Shen, Kun Wang, Li Xu, Peizhang Wu, Jianbing Ren, Donglin Wang
Article Number: 145
Published online on: 30 March 2026

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Role of itaconate in intestinal disease (Review)

Xin Li, Qian Liu, Jiajia Li, Li Zhang, Shun Yao, Lulu Tang, Bingqi Yang, Yongfeng Wang, Guorong Wen, Jiaxing An, Hai Jin, Biguang Tuo
Article Number: 144
Published online on: 27 March 2026

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Unveiling lactylation: A novel frontier in the pathogenesis of diabetic nephropathy (Review)

Yuanyuan Xiao, Niansong Wang, Dingkun Gui, Youhua Xu
Article Number: 143
Published online on: 27 March 2026

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Crosstalk between autophagy and ferroptosis in liver diseases (Review)

Yanming Wei, Kun Zhou, Yuerui Su, Zhihua Luan, Pengcheng Li, Yinxia Chang, Bo Han, Huifang Li, Yuanbiao Qiao, Jinhong Ren
Article Number: 142
Published online on: 26 March 2026

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circOMA1 delivered by exosomes regulates DRD2‑mediated prolactinoma resistance

Qing Rao, Dimin Zhu, Zongming Wang, Shaolin Zhang, Xueli Li, Shashikiran Tagilapalli, Nan Wang, Weiyu Hu, Wenli Chen, Yonghong Zhu
Article Number: 141
Published online on: 26 March 2026

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Expression of Concern Open Access

[Expression of Concern] Involvement of Cyr61 in the growth, invasiveness and adhesion of esophageal squamous cell carcinoma cells

Jian-Jun Xie, Li-Yan Xu, Yang-Min Xie, Ze-Peng Du, Cai-Hua Feng, Hui Dong, En-Min Li
Article Number: 140
Published online on: 24 March 2026

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Article Open Access

Novel Hsp90 inhibitor JD‑02 inhibits HSV‑1 infection via the Raf/MEK/ERK signaling pathway

Yexuan Zhu, Xiaohui Wang, Jiaying Lin, Xiao Wang, Kai Zheng, Zhe Ren, Ji Xiao, Yifei Wang
Article Number: 139
Published online on: 24 March 2026

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