Journal Articles
Review
The gonadotropin-releasing hormone system: Perspectives from reproduction to cancer (Review)
Arturo Aguilar-Rojas, Marco Allan Pérez-Solis, Guadalupe Maya-Núñez
Pages: 861-868 Published online on: 19 January 2016
Review
Akt inhibitors in cancer treatment: The long journey from drug discovery to clinical use (Review)
George Mihai Nitulescu, Denisa Margina, Petras Juzenas, Qian Peng, Octavian Tudorel Olaru, Emmanouil Saloustros, Concettina Fenga, Demetrios Α. Spandidos, Massimo Libra, Aristidis M. Tsatsakis
Pages: 869-885 Published online on: 24 December 2015
Review
Involvement of F-box proteins in esophageal cancer (Review)
Jian Gong, Zheng Huang, Ji-Rong Huo
Pages: 886-894 Published online on: 05 January 2016
Review
Personalization of the medical treatment of solid tumours using patient-derived tumour explants (Review)
Christophe Louandre, Jérome Donnadieu, Emma Lachaier, Cyril Page, Bruno Chauffert, Antoine Galmiche
Pages: 895-899 Published online on: 18 January 2016
Article
The clinical utility of CA125/MUC16 in pancreatic cancer: A consensus of diagnostic, prognostic and predictive updates by the Chinese Study Group for Pancreatic Cancer (CSPAC)
Liang Liu, Jinfeng Xiang, Rufu Chen, Deliang Fu, Defei Hong, Jihui Hao, Yixiong Li, Jiangtao Li, Shengping Li, Yiping Mou, Gang Mai, Quanxing Ni, Li Peng, Renyi Qin, Honggang Qian, Chenghao Shao, Bei Sun, Yongwei Sun, Min Tao, Bole Tian, Hongxia Wang, Jian Wang, Liwei Wang, Wei Wang, Weilin Wang, Jun Zhang, Gang Zhao, Jun Zhou, Xianjun Yu
Pages: 900-907 Published online on: 30 December 2015
Article
Acquired resistance of pancreatic cancer cells to treatment with gemcitabine and HER-inhibitors is accompanied by increased sensitivity to STAT3 inhibition
Nikolaos Ioannou, Alan M. Seddon, Angus Dalgleish, David Mackintosh, Flavio Solca, Helmout Modjtahedi
Pages: 908-918 Published online on: 05 January 2016
Article
Importance of osteoprotegrin and receptor activator of nuclear factor κB in breast cancer response to hepatocyte growth factor and the bone microenvironment in vitro
Sioned Owen, Andrew J. Sanders, Malcolm D. Mason, Wen G. Jiang
Pages: 919-928 Published online on: 15 January 2016
Article
Effect of junctional adhesion molecule-2 expression on cell growth, invasion and migration in human colorectal cancer
Huishan Zhao, Hefen Yu, Tracey A. Martin, Yuxiang Zhang, Gang Chen, Wen G. Jiang
Pages: 929-936 Published online on: 15 January 2016
Article
miR-200/ZEB axis regulates sensitivity to nintedanib in non-small cell lung cancer cells
Nobuhiko Nishijima, Masahiro Seike, Chie Soeno, Mika Chiba, Akihiko Miyanaga, Rintaro Noro, Teppei Sugano, Masaru Matsumoto, Kaoru Kubota, Akihiko Gemma
Pages: 937-944 Published online on: 11 January 2016
Article
Identification of haptoglobin peptide as a novel serum biomarker for lung squamous cell carcinoma by serum proteome and peptidome profiling
Tetsuya Okano, Masahiro Seike, Hidehiko Kuribayashi, Chie Soeno, Takeo Ishii, Kozui Kida, Akihiko Gemma
Pages: 945-952 Published online on: 11 January 2016
Article
Dendritic cells pulsed with tumor cells killed by high hydrostatic pressure induce strong immune responses and display therapeutic effects both in murine TC-1 and TRAMP-C2 tumors when combined with docetaxel chemotherapy
Romana Mikyšková, Ivan Štěpánek, Marie Indrová, Jana Bieblová, Jana Šímová, Iva Truxová, Irena Moserová, Jitka Fučíková, Jiřina Bartůňková, Radek Špíšek, Milan Reiniš
Pages: 953-964 Published online on: 29 December 2015
Article
MicroRNA-519a promotes tumor growth by targeting PTEN/PI3K/AKT signaling in hepatocellular carcinoma
Kangsheng Tu, Zhikui Liu, Bowen Yao, Shaoshan Han, Wei Yang
Pages: 965-974 Published online on: 28 December 2015
Article
Overexpression of the S100A2 protein as a prognostic marker for patients with stage II and III colorectal cancer
Taiki Masuda, Toshiaki Ishikawa, Kaoru Mogushi, Satoshi Okazaki, Megumi Ishiguro, Satoru Iida, Hiroshi Mizushima, Hiroshi Tanaka, Hiroyuki Uetake, Kenichi Sugihara
Pages: 975-982 Published online on: 11 January 2016
Article
PP2B and ERK1/2 regulate hyaluronan synthesis of HT168 and WM35 human melanoma cell lines
Éva Katona, Tamás Juhász, Csilla Szűcs Somogyi, Tibor Hajdú, Csaba Szász, Kálmán Rácz, Endre Kókai, Pál Gergely, Róza Zákány
Pages: 983-997 Published online on: 28 December 2015
Article
The relationship of the angiogenesis regulators VEGF-A, VEGF-R1 and VEGF-R2 to p53 status and prognostic factors in epithelial ovarian carcinoma in FIGO-stages I-II
Ingiridur Skirnisdottir, Tomas Seidal, Helena Åkerud
Pages: 998-1006 Published online on: 12 January 2016
Article
Insulin-like growth factor 2 mRNA-binding protein-3 as a marker for distinguishing between cutaneous squamous cell carcinoma and keratoacanthoma
Akiko Kanzaki, Mitsuhiro Kudo, Shin-Ichi Ansai, Wei-Xia Peng, Kousuke Ishino, Tetsushi Yamamoto, Ryuichi Wada, Takenori Fujii, Kiyoshi Teduka, Kiyoko Kawahara, Yoko Kawamoto, Taeko Kitamura, Seiji Kawana, Hidehisa Saeki, Zenya Naito
Pages: 1007-1015 Published online on: 05 January 2016
Article
Quantitative phosphoproteomics reveals genistein as a modulator of cell cycle and DNA damage response pathways in triple-negative breast cancer cells
Yi Fang, Qian Zhang, Xin Wang, Xue Yang, Xiangyu Wang, Zhen Huang, Yuchen Jiao, Jing Wang
Pages: 1016-1028 Published online on: 11 January 2016
Article
High levels of apoptosis are induced in human glioma cell lines by co-administration of peptide nucleic acids targeting miR-221 and miR-222
Eleonora Brognara, Enrica Fabbri, Giulia Montagner, Jessica Gasparello, Alex Manicardi, Roberto Corradini, Nicoletta Bianchi, Alessia Finotti, Giulia Breveglieri, Monica Borgatti, Ilaria Lampronti, Roberta Milani, Maria Cristina Dechecchi, Giulio Cabrini, Roberto Gambari
Pages: 1029-1038 Published online on: 24 December 2015
Article
The secreted protein acidic and rich in cysteine is a critical mediator of cell death program induced by WIN/TRAIL combined treatment in osteosarcoma cells
Antonietta Notaro, Selenia Sabella, Ornella Pellerito, Renza Vento, Giuseppe Calvaruso, Michela Giuliano
Pages: 1039-1044 Published online on: 24 December 2015
Article
ATP-site binding inhibitor effectively targets mTORC1 and mTORC2 complexes in glioblastoma
Jayson Neil, Craig Shannon, Avinash Mohan, Dimitri Laurent, Raj Murali, Meena Jhanwar-Uniyal
Pages: 1045-1052 Published online on: 28 December 2015
Article
Involvement of DDX6 gene in radio- and chemoresistance in glioblastoma
Yu Jin Cho, Wonyoung Kang, Sung Heon Kim, Jason K. Sa, Nayoung Kim, Patrick J. Paddison, Misuk Kim, Kyeung Min Joo, Young-Il Hwang, Do-Hyun Nam
Pages: 1053-1062 Published online on: 11 January 2016
Article
Genistein-induced differentiation of breast cancer stem/progenitor cells through a paracrine mechanism
Yanchen Liu, Tianbiao Zou, Shuhuai Wang, Hong Chen, Dongju Su, Xiaona Fu, Qingyuan Zhang, Xinmei Kang
Pages: 1063-1072 Published online on: 19 January 2016
Article
Quinalizarin enhances radiosensitivity of nasopharyngeal carcinoma cells partially by suppressing SHP-1 expression
Xiaofen Pan, Rui Meng, Zhonghua Yu, Jingjing Mou, Sha Liu, Ziyi Sun, Zhenwei Zou, Gang Wu, Gang Peng
Pages: 1073-1084 Published online on: 14 January 2016
Article
Overexpression of SDF-1 activates the NF-κB pathway to induce epithelial to mesenchymal transition and cancer stem cell-like phenotypes of breast cancer cells
Lingxin Kong, Sufen Guo, Chunfeng Liu, Yiling Zhao, Chong Feng, Yunshuang Liu, Tao Wang, Caijuan Li
Pages: 1085-1094 Published online on: 15 January 2016
Article
Tamoxifen enhances the differentiation-inducing and growth-inhibitory effects of all-trans retinoic acid in acute promyelocytic leukemia cells
Koji Adachi, Yoshio Honma, Takaaki Miyake, Koshi Kawakami, Tsutomu Takahashi, Junji Suzumiya
Pages: 1095-1102 Published online on: 19 January 2016
Article
Estimation of copy number aberrations: Comparison of exome sequencing data with SNP microarrays identifies homozygous deletions of 19q13.2 and CIC in neuroblastoma
Susanne Fransson, Malin Östensson, Anna Djos, Niloufar Javanmardi, Per Kogner, Tommy Martinsson
Pages: 1103-1116 Published online on: 19 January 2016
Article
Twist mediates an aggressive phenotype in human colorectal cancer cells
Jun-Jian Deng, Wei Zhang, Xi-Ming Xu, Fan Zhang, Wei-Ping Tao, Jun-Jie Ye, Wei Ge
Pages: 1117-1124 Published online on: 15 January 2016
Article
AP-2α inhibits hepatocellular carcinoma cell growth and migration
Wenhuan Huang, Cheng Chen, Zhongheng Liang, Junlu Qiu, Xinxin Li, Xiang Hu, Shuanglin Xiang, Xiaofeng Ding, Jian Zhang
Pages: 1125-1134 Published online on: 05 January 2016
Article
Tumor suppressive microRNA-138 inhibits metastatic potential via the targeting of focal adhesion kinase in Ewing's sarcoma cells
Kazuhiro Tanaka, Masanori Kawano, Ichiro Itonaga, Tatsuya Iwasaki, Masashi Miyazaki, Shinichi Ikeda, Hiroshi Tsumura
Pages: 1135-1144 Published online on: 05 January 2016
Article
Screening of mammalian DNA polymerase and topoisomerase inhibitors from Garcinia mangostana L. and analysis of human cancer cell proliferation and apoptosis
Takefumi Onodera, Yukiko Takenaka, Sachiko Kozaki, Takao Tanahashi, Yoshiyuki Mizushina
Pages: 1145-1154 Published online on: 05 January 2016
Article
Downregulation of β3 integrin by miR-30a-5p modulates cell adhesion and invasion by interrupting Erk/Ets‑1 network in triple-negative breast cancer Corrigendum in /10.3892/ijo.2021.5169
Wentong Li, Chuanliang Liu, Chunling Zhao, Limin Zhai, Shijun Lv
Pages: 1155-1164 Published online on: 05 January 2016
Article
Galectin-9: An anticancer molecule for gallbladder carcinoma
Tomoko Tadokoro, Asahiro Morishita, Shintaro Fujihara, Hisakazu Iwama, Toshiro Niki, Koji Fujita, Emiko Akashi, Shima Mimura, Kyoko Oura, Teppei Sakamoto, Takako Nomura, Joji Tani, Hisaaki Miyoshi, Hirohito Yoneyama, Takashi Himoto, Mitsuomi Hirashima, Tsutomu Masaki
Pages: 1165-1174 Published online on: 19 January 2016
Article
WNT pathway inhibitor pyrvinium pamoate inhibits the self-renewal and metastasis of breast cancer stem cells
Liang Xu, Le Zhang, Chun Hu, Shujing Liang, Xiaochun Fei, Ningning Yan, Yanyun Zhang, Fengchun Zhang
Pages: 1175-1186 Published online on: 13 January 2016
Article
Cytotoxic mechanism of PLK1 inhibitor GSK461364 against osteosarcoma: Mitotic arrest, apoptosis, cellular senescence, and synergistic effect with paclitaxel
Yi-Sheng Chou, Chueh-Chuan Yen, Wei-Ming Chen, Yung-Chan Lin, Yao-Shan Wen, Wei-Ting Ke, Jir-You Wang, Chun-Yu Liu, Muh-Hwa Yang, Tain-Hsiung Chen, Chien-Lin Liu
Pages: 1187-1194 Published online on: 20 January 2016
Article
A double-negative feedback loop between EZH2 and miR-26a regulates tumor cell growth in hepatocellular carcinoma
Chunbo Zhuang, Pei Wang, Da Huang, Luming Xu, Xiaobei Wang, Lin Wang, Lihua Hu
Pages: 1195-1204 Published online on: 13 January 2016
Article
Transformation of primary human hepatocytes in hepatocellular carcinoma
Mauro Montalbano, Cristiana Rastellini, Xiaofu Wang, Tiziana Corsello, Mahmoud A. Eltorky, Renza Vento, Luca Cicalese
Pages: 1205-1217 Published online on: 28 December 2015
Article
The antitumor efficacy of a novel adenovirus-mediated anti-p21Ras single chain fragment variable antibody on human cancers in vitro and in vivo
Ju-Lun Yang, Xin-Yan Pan, Wen-Xing Zhao, Qi-Chan Hu, Feng Ding, Qiang Feng, Gui-Yun Li, Ying Luo
Pages: 1218-1228 Published online on: 13 January 2016
Article
Bufalin enhances anti-angiogenic effect of sorafenib via AKT/VEGF signaling
Haiyong Wang, Chenyue Zhang, Zhouyu Ning, Litao Xu, Xiaoyan Zhu, Zhiqiang Meng
Pages: 1229-1241 Published online on: 05 January 2016
Article
Fusion of the TBL1XR1 and HMGA1 genes in splenic hemangioma with t(3;6)(q26;p21)
Ioannis Panagopoulos, Ludmila Gorunova, Bodil Bjerkehagen, Ingvild Lobmaier, Sverre Heim
Pages: 1242-1250 Published online on: 28 December 2015
Article
RhoA mediates the expression of acidic extracellular pH-induced matrix metalloproteinase-9 mRNA through phospholipase D1 in mouse metastatic B16-BL6 melanoma cells
Toyonobu Maeda, Satoshi Yuzawa, Atsuko Suzuki, Yuh Baba, Yukio Nishimura, Yasumasa Kato
Pages: 1251-1257 Published online on: 05 January 2016
Article
Surface vacuolar ATPase in ameloblastoma contributes to tumor invasion of the jaw bone
Shohei Yoshimoto, Hiromitsu Morita, Ryota Matsubara, Takeshi Mitsuyasu, Yuko Imai, Shunichi Kajioka, Masahiro Yoneda, Yushi Ito, Takao Hirofuji, Seiji Nakamura, Masato Hirata
Pages: 1258-1270 Published online on: 19 January 2016
Article
1,25-Dihydroxyvitamin D3 alleviates salivary adenoid cystic carcinoma progression by suppressing GPX1 expression through the NF-κB pathway
Zhiquan Huang, Yeqing Liu, Zixian Huang, Haifeng Li, Xiangfeng Gan, Zhuojian Shen
Pages: 1271-1279 Published online on: 15 January 2016
Article
Optimizing treatment of hepatic metastases from colorectal cancer: Resection or resection plus ablation?
Antonio Chiappa, Emilio Bertani, Andrew P. Zbar, Diego Foschi, Nicola Fazio, Maria Zampino, Claudio Belluco, Franco Orsi, Paolo Della Vigna, Guido Bonomo, Marco Venturino, Carlo Ferrari, Roberto Biffi
Pages: 1280-1289 Published online on: 05 January 2016
Article
KAT5 (Tip60) is a potential therapeutic target in malignant pleural mesothelioma
Sian Cregan, Lauran McDonagh, Yun Gao, Martin P. Barr, Kenneth J. O'Byrne, Stephen P. Finn, Sinead Cuffe, Steven G. Gray
Pages: 1290-1296 Published online on: 13 January 2016
Article
Phosphorylated retinoblastoma protein is a potential predictive marker of irinotecan efficacy for colorectal cancer
Atsushi Ikai, Motoki Watanabe, Yoshihiro Sowa, Mitsuo Kishimoto, Akio Yanagisawa, Hitoshi Fujiwara, Eigo Otsuji, Toshiyuki Sakai
Pages: 1297-1304 Published online on: 12 January 2016
Correction
[Corrigendum] Brassinin induces G1 phase arrest through increase of p21 and p27 by inhibition of the phosphatidylinositol 3-kinase signaling pathway in human colon cancer cells
Yasuyuki Izutani, Shingo Yogosawa, Yoshihiro Sowa, Toshiyuki Sakai
Pages: 1305-1305 Published online on: 30 December 2015
Correction
