Journal Articles
Review
Role of ribosomal protein mutations in tumor development (Review)
Kaveh M. Goudarzi, Mikael S. Lindström
Pages: 1313-1324 Published online on: 09 February 2016
Article
PET imaging of epidermal growth factor receptor expression in tumours using 89Zr-labelled ZEGFR:2377 affibody molecules
Javad Garousi, Ken G. Andersson, Bogdan Mitran, Marie-Louise Pichl, Stefan Ståhl, Anna Orlova, John Löfblom, Vladimir Tolmachev
Pages: 1325-1332 Published online on: 02 February 2016
Article
Tankyrase 1 inhibitior XAV939 increases chemosensitivity in colon cancer cell lines via inhibition of the Wnt signaling pathway
Xuefang Wu, Feng Luo, Jinbang Li, Xueyun Zhong, Kunping Liu
Pages: 1333-1340 Published online on: 26 January 2016
Article
Repertaxin, an inhibitor of the chemokine receptors CXCR1 and CXCR2, inhibits malignant behavior of human gastric cancer MKN45 cells in vitro and in vivo and enhances efficacy of 5-fluorouracil
Junpu Wang, Wanming Hu, Kuansong Wang, Jun Yu, Baihua Luo, Gengqiu Luo, Weiyuan Wang, Huiling Wang, Jinghe Li, Jifang Wen
Pages: 1341-1352 Published online on: 02 February 2016
Article
New application of an old drug: Antitumor activity and mechanisms of doxycycline in small cell lung cancer
Sheng-Qi Wang, Bo-Xin Zhao, Yuan Liu, Ya-Tian Wang, Qian-Ying Liang, Yun Cai, Yun-Qi Zhang, Jiang-Hong Yang, Zhi-Hua Song, Guo-Feng Li
Pages: 1353-1360 Published online on: 04 February 2016
Article
Detection of metastatic tumors after γ-irradiation using longitudinal molecular imaging and gene expression profiling of metastatic tumor nodules
Su Jin Jang, Joo Hyun Kang, Yong Jin Lee, Kwang Il Kim, Tae Sup Lee, Jae Gol Choe, Sang Moo Lim
Pages: 1361-1368 Published online on: 08 February 2016
Article
Triple peptide vaccination as consolidation treatment in women affected by ovarian and breast cancer: Clinical and immunological data of a phase I/II clinical trial
Morena Antonilli, Hassan Rahimi, Valeria Visconti, Chiara Napoletano, Ilary Ruscito, Ilaria Grazia Zizzari, Salvatore Caponnetto, Giacomo Barchiesi, Roberta Iadarola, Luca Pierelli, Aurelia Rughetti, Filippo Bellati, Pierluigi Benedetti Panici, Marianna Nuti
Pages: 1369-1378 Published online on: 08 February 2016
Article
Impaired mitophagy activates mtROS/HIF-1α interplay and increases cancer aggressiveness in gastric cancer cells under hypoxia
Masaaki Shida, Yoshihiko Kitajima, Jun Nakamura, Kazuyoshi Yanagihara, Koichi Baba, Kota Wakiyama, Hirokazu Noshiro
Pages: 1379-1390 Published online on: 26 January 2016
Article
Overexpression of KiSS-1 reduces colorectal cancer cell invasion by downregulating MMP-9 via blocking PI3K/Akt/NF-κB signal pathway
Shaoqin Chen, Wei Chen, Xiang Zhang, Suyong Lin, Zhihua Chen
Pages: 1391-1398 Published online on: 02 February 2016
Article
Downregulation of thymidylate synthase by RNAi molecules enhances the antitumor effect of pemetrexed in an orthotopic malignant mesothelioma xenograft mouse model
Amr S. Abu Lila, Chihiro Kato, Masakazu Fukushima, Cheng-Long Huang, Hiromi Wada, Tatsuhiro Ishida
Pages: 1399-1407 Published online on: 01 February 2016
Article
Differential expression of CXCR4 and CXCR7 with various stem cell markers in paired human primary and recurrent glioblastomas
Charlotte Flüh, Kirsten Hattermann, H. Maximilian Mehdorn, Michael Synowitz, Janka Held-Feindt
Pages: 1408-1416 Published online on: 25 January 2016
Article
Tyrosine receptor kinase B silencing inhibits anoikis‑resistance and improves anticancer efficiency of sorafenib in human renal cancer cells
Peng Zhang, Zengshu Xing, Xuechao Li, Yarong Song, Jun Zhao, Yajun Xiao, Yifei Xing
Pages: 1417-1425 Published online on: 25 January 2016
Article
Piperlongumine exerts cytotoxic effects against cancer cells with mutant p53 proteins at least in part by restoring the biological functions of the tumor suppressor
Debasish Basak, Surendra R. Punganuru, Kalkunte S. Srivenugopal
Pages: 1426-1436 Published online on: 03 February 2016
Article
Quantitative proteomic study of human prostate cancer cells with different metastatic potentials
Qun Li, Yilei Li, Yanying Wang, Zheng Cui, Lulu Gong, Zhigang Qu, Yanping Zhong, Jun Zhou, Ying Zhou, Yong Gao, Yulin Li
Pages: 1437-1446 Published online on: 04 February 2016
Article
Fibulin-5 downregulates Ki-67 and inhibits proliferation and invasion of breast cancer cells
Yamina Mohamedi, Tania Fontanil, Laura Solares, Olivia Garcia-Suárez, Jorge García-Piqueras, Jose A. Vega, Santiago Cal, Alvaro J. Obaya
Pages: 1447-1456 Published online on: 17 February 2016
Article
The effect of NFATc1 on vascular generation and the possible underlying mechanism in epithelial ovarian carcinoma Corrigendum in /10.3892/ijo.2020.5131 Corrigendum in /10.3892/ijo.2022.5318
Long Li, Jihui Yu, Zhaoning Duan, Hong-Xing Dang
Pages: 1457-1466 Published online on: 25 January 2016
Article
The preventative effect of Akt knockout on liver cancer through modulating NF-κB-regulated inflammation and Bad-related apoptosis signaling pathway
Bin Hu, Ming Sun, Jiajun Liu, Guolin Hong, Qin Lin
Pages: 1467-1476 Published online on: 08 February 2016
Article
Regorafenib as a potential adjuvant chemotherapy agent in disseminated small colon cancer: Drug selection outcome of a novel screening system using nanoimprinting 3-dimensional culture with HCT116-RFP cells
Yukie Yoshii, Takako Furukawa, Hironori Aoyama, Naoya Adachi, Ming-Rong Zhang, Hidekatsu Wakizaka, Yasuhisa Fujibayashi, Tsuneo Saga
Pages: 1477-1484 Published online on: 28 January 2016
Article
High-mobility group AT-hook protein 2 expression and its prognostic significance in MGMT methylated and unmethylated glioblastoma
Frank P. Schwarm, Florian Uhle, Anne Schänzer, Till Acker, Marco Stein, Marcus H.T. Reinges, Cornelia Weischer, Marcus A. Weigand, Eberhard Uhl, Malgorzata A. Kolodziej
Pages: 1485-1492 Published online on: 17 February 2016
Article
Transcutaneous carbon dioxide suppresses epithelial-mesenchymal transition in oral squamous cell carcinoma
Eiji Iwata, Takumi Hasegawa, Daisuke Takeda, Takeshi Ueha, Teruya Kawamoto, Toshihiro Akisue, Yoshitada Sakai, Takahide Komori
Pages: 1493-1498 Published online on: 05 February 2016
Article
Suppression of CD51 in pancreatic stellate cells inhibits tumor growth by reducing stroma and altering tumor-stromal interaction in pancreatic cancer
Kohei Horioka, Kenoki Ohuchida, Masafumi Sada, Biao Zheng, Taiki Moriyama, Hayato Fujita, Tatsuya Manabe, Takao Ohtsuka, Masaya Shimamoto, Tetsuyuki Miyazaki, Kazuhiro Mizumoto, Yoshinao Oda, Masafumi Nakamura
Pages: 1499-1508 Published online on: 03 February 2016
Article
Lentiviral-mediated overexpression of long non-coding RNA GAS5 reduces invasion by mediating MMP2 expression and activity in human melanoma cells
Long Chen, Huixin Yang, Yanbin Xiao, Xiaoxia Tang, Yuqian Li, Qiaoqiao Han, Junping Fu, Yuye Yang, Yuechun Zhu
Pages: 1509-1518 Published online on: 04 February 2016
Article
Triptolide decreases expression of latency-associated nuclear antigen 1 and reduces viral titers in Kaposi's sarcoma-associated and herpesvirus-related primary effusion lymphoma cells
Cong Long, Wei Guo, Heng Zhou, Jingchao Wang, Huan Wang, Xiaoping Sun
Pages: 1519-1530 Published online on: 25 January 2016
Article
MicroRNA-301a promotes cell proliferation via PTEN targeting in Ewing's sarcoma cells
Masanori Kawano, Kazuhiro Tanaka, Ichiro Itonaga, Tatsuya Iwasaki, Hiroshi Tsumura
Pages: 1531-1540 Published online on: 05 February 2016
Article
Upregulation of metastasis-associated PRL-3 initiates chordoma in zebrafish
Li Li, Hongshun Shi, Mingming Zhang, Xiaoling Guo, Fang Tong, Wenliang Zhang, Junyi Zhou, Haihe Wang, Shulan Yang
Pages: 1541-1552 Published online on: 29 January 2016
Article
Suppression of lysyl-tRNA synthetase, KRS, causes incomplete epithelial-mesenchymal transition and ineffective cell‑extracellular matrix adhesion for migration
Seo Hee Nam, Minkyung Kang, Jihye Ryu, Hye-Jin Kim, Doyeun Kim, Dae Gyu Kim, Nam Hoon Kwon, Sunghoon Kim, Jung Weon Lee
Pages: 1553-1560 Published online on: 08 February 2016
Article
Knockdown of B7-H6 inhibits tumor progression and enhances chemosensitivity in B-cell non-Hodgkin lymphoma
Feifei Wu, Jing Wang, Xiaoyan Ke
Pages: 1561-1570 Published online on: 17 February 2016
Article
Genomic profiling of the genes on chromosome 3p in sporadic clear cell renal cell carcinoma
Yoshikazu Togo, Yoshie Yoshikawa, Toru Suzuki, Yoshiro Nakano, Akihiro Kanematsu, Masataka Zozumi, Michio Nojima, Seiichi Hirota, Shingo Yamamoto, Tomoko Hashimoto-Tamaoki
Pages: 1571-1580 Published online on: 17 February 2016
Article
Placenta growth factor and neuropilin-1 collaborate in promoting melanoma aggressiveness
Elena Pagani, Federica Ruffini, Gian Carlo Antonini Cappellini, Alessandro Scoppola, Cristina Fortes, Paolo Marchetti, Grazia Graziani, Stefania D'Atri, Pedro Miguel Lacal
Pages: 1581-1589 Published online on: 29 January 2016
Article
Long noncoding RNA AFAP1-AS1 indicates a poor prognosis of hepatocellular carcinoma and promotes cell proliferation and invasion via upregulation of the RhoA/Rac2 signaling
Jin-Yan Zhang, Ming-Zhe Weng, Fang-Bin Song, Yong-Gang Xu, Qi Liu, Jun-Yi Wu, Jun Qin, Tao Jin, Jun-Ming Xu
Pages: 1590-1598 Published online on: 08 February 2016
Article
Differential microRNA expression profiling of mesothelioma and expression analysis of miR-1 and miR-214 in mesothelioma
Vishwa Jeet Amatya, Amany Sayed Mawas, Kei Kushitani, Mouchira M. Mohi El-Din, Yukio Takeshima
Pages: 1599-1607 Published online on: 26 January 2016
Article
Scrophularia orientalis extract induces calcium signaling and apoptosis in neuroblastoma cells
Ingo Lange, Julia Moschny, Kamilla Tamanyan, Manana Khutsishvili, Daniel Atha, Robert P. Borris, Dana-Lynn Koomoa
Pages: 1608-1616 Published online on: 03 February 2016
Article
Gene expression profiling of microRNAs associated with UCA1 in bladder cancer cells
Xiaojuan Xie, Jingjing Pan, Liqiang Wei, Shouzhen Wu, Huilian Hou, Xu Li, Wei Chen
Pages: 1617-1627 Published online on: 25 January 2016
Article
Ribosomal protein S15A promotes malignant transformation and predicts poor outcome in colorectal cancer through misregulation of p53 signaling pathway
Jingwen Chen, Ye Wei, Qingyang Feng, Li Ren, Guodong He, Wenju Chang, Dexiang Zhu, Tuo Yi, Qi Lin, Wentao Tang, Jianmin Xu, Xinyu Qin
Pages: 1628-1638 Published online on: 01 February 2016
Article
Tripartite motif 16 inhibits hepatocellular carcinoma cell migration and invasion Retraction in /10.3892/ijo.2023.5473
Linlin Li, Lei Dong, Xiaotong Qu, Shi Jin, Xiupeng Lv, Guang Tan
Pages: 1639-1649 Published online on: 17 February 2016
Article
E2F1 promotes tumor cell invasion and migration through regulating CD147 in prostate cancer
Yu-Xiang Liang, Jian-Ming Lu, Ru-Jun Mo, Hui-Chan He, Jian Xie, Fu-Neng Jiang, Zhuo-Yuan Lin, Yan-Ru Chen, Yong-Ding Wu, Hong-Wei Luo, Zheng Luo, Wei-De Zhong
Pages: 1650-1658 Published online on: 29 January 2016
Article
Adrenomedullin in the growth modulation and differentiation of acute myeloid leukemia cells
Rosa Di Liddo, Deborah Bridi, Michele Gottardi, Sergio De Angeli, Claudio Grandi, Alessia Tasso, Thomas Bertalot, Giovanni Martinelli, Filippo Gherlinzoni, Maria Teresa Conconi
Pages: 1659-1669 Published online on: 02 February 2016
Article
Agarol, an ergosterol derivative from Agaricus blazei, induces caspase-independent apoptosis in human cancer cells
Takamitsu Shimizu, Junya Kawai, Kenji Ouchi, Haruhisa Kikuchi, Yoshiteru Osima, Rikiishi Hidemi
Pages: 1670-1678 Published online on: 15 February 2016
Article
Cellular apoptosis susceptibility (CAS) is overexpressed in thyroid carcinoma and maintains tumor cell growth: A potential link to the BRAFV600E mutation
Kerstin Holzer, Elisabeth Drucker, Scott Oliver, Juliane Winkler, Eva Eiteneuer, Esther Herpel, Kai Breuhahn, Stephan Singer
Pages: 1679-1687 Published online on: 09 February 2016
Article
Overexpression of microRNA-5100 decreases the aggressive phenotype of pancreatic cancer cells by targeting PODXL
Yoshiro Chijiiwa, Taiki Moriyama, Kenoki Ohuchida, Toshinaga Nabae, Takao Ohtsuka, Yoshihiro Miyasaka, Hayato Fujita, Ryo Maeyama, Tatsuya Manabe, Atsushi Abe, Yusuke Mizuuchi, Yoshinao Oda, Kazuhiro Mizumoto, Masafumi Nakamura
Pages: 1688-1700 Published online on: 12 February 2016
Article
Development of three-dimensional lung multicellular spheroids in air- and liquid-interface culture for the evaluation of anticancer therapeutics
Samantha A. Meenach, Alexandra N. Tsoras, Ronald C. McGarry, Heidi M. Mansour, J. Zach Hilt, Kimberly W. Anderson
Pages: 1701-1709 Published online on: 04 February 2016
Article
Hsp90 inhibitor, BIIB021, induces apoptosis and autophagy by regulating mTOR-Ulk1 pathway in imatinib-sensitive and -resistant chronic myeloid leukemia cells
Wei He, Xiujin Ye, Xianbo Huang, Wen Lel, Liangshun You, Lei Wang, Xiaohui Chen, Wenbin Qian
Pages: 1710-1720 Published online on: 08 February 2016
Article
The milk-derived hexapeptide PGPIPN inhibits the invasion and migration of human ovarian cancer cells by regulating the expression of MTA1 and NM23H1 genes
Mengjing Zhao, Cai Wei, Xue Yang, Juan Zhou, Jing Wang, Fang Gu, Ting Lei, Yide Qin
Pages: 1721-1729 Published online on: 12 February 2016
Article
Downregulation of cytokeratin 18 is associated with paclitaxel‑resistance and tumor aggressiveness in prostate cancer
Bo Yin, Mo Zhang, Yu Zeng, Youqiang Li, Chao Zhang, Yongsheng Song
Pages: 1730-1736 Published online on: 17 February 2016
Article
miR-17-92 plays an oncogenic role and conveys chemo-resistance to cisplatin in human prostate cancer cells
Peng Zhou, Liang Ma, Jun Zhou, Min Jiang, Enyu Rao, Yong Zhao, Feng Guo
Pages: 1737-1748 Published online on: 15 February 2016
Article