Journal Articles

Review Open Access

Breast cancer in European Union: An update of screening programmes as of March 2014 (Review)

E. Altobelli, A. Lattanzi

Pages: 1785-1792 Published online on: 01 September 2014
Review

Targeting the PI3K/Akt pathway in prostate cancer: Challenges and opportunities (Review)

Paul Toren, Amina Zoubeidi

Pages: 1793-1801 Published online on: 14 August 2014
Review

Pharmacological and dietary agents for colorectal cancer chemoprevention: Effects on polyamine metabolism (Review)

Michele Linsalata, Antonella Orlando, Francesco Russo

Pages: 1802-1812 Published online on: 14 August 2014
Review

Radiation-induced signaling pathways that promote cancer cell survival (Review)

Ashley L. Hein, Michel M. Ouellette, Ying Yan

Pages: 1813-1819 Published online on: 20 August 2014
Article

The role of APE/Ref-1 signaling pathway in hepatocellular carcinoma progression

Zhen Yang, Sun Yang, Bobbye J. Misner, Feng Liu-Smith, Frank L. Meyskens

Pages: 1820-1828 Published online on: 08 August 2014
Article Open Access

Several fusion genes identified by whole transcriptome sequencing in a spindle cell sarcoma with rearrangements of chromosome arm 12q and MDM2 amplification

Ioannis Panagopoulos, Bodil Bjerkehagen, Ludmila Gorunova, Jeanne-Marie Berner, Kjetil Boye, Sverre Heim

Pages: 1829-1836 Published online on: 18 August 2014
Article Open Access

Interferon-β inhibits glioma angiogenesis through downregulation of vascular endothelial growth factor and upregulation of interferon inducible protein 10

Shingo Takano, Eiichi Ishikawa, Masahide Matsuda, Tetsuya Yamamoto, Akira Matsumura

Pages: 1837-1846 Published online on: 25 August 2014
Article Open Access

Large-scale expansion of γδ T cells and peptide-specific cytotoxic T cells using zoledronate for adoptive immunotherapy

Toshiaki Yoshikawa, Masashi Takahara, Mai Tomiyama, Mie Nieda, Ryuji Maekawa, Tetsuya Nakatsura

Pages: 1847-1856 Published online on: 03 September 2014
Article Open Access

A stem cell medium containing neural stimulating factor induces a pancreatic cancer stem-like cell-enriched population

Yusaku Watanabe, Kiyoshi Yoshimura, Koichi Yoshikawa, Ryoichi Tsunedomi, Yoshitaro Shindo, Sou Matsukuma, Noriko Maeda, Shinsuke Kanekiyo, Nobuaki Suzuki, Atsuo Kuramasu, Kouhei Sonoda, Koji Tamada, Sei Kobayashi, Hideyuki Saya, Shoichi Hazama, Masaaki Oka

Pages: 1857-1866 Published online on: 14 August 2014
Article

Significance of serine threonine tyrosine kinase 1 as a drug resistance factor and therapeutic predictor in acute leukemia

Shinya Nirasawa, Daisuke Kobayashi, Takashi Kondoh, Kageaki Kuribayashi, Maki Tanaka, Nozomi Yanagihara, Naoki Watanabe

Pages: 1867-1874 Published online on: 03 September 2014
Article

Overexpression of integrin αv facilitates proliferation and invasion of oral squamous cell carcinoma cells via mek/erk signaling pathway that is activated by interaction of integrin αvβ8 with type Ⅰ collagen

Yasutaka Hayashido, Hisataka Kitano, Taishi Sakaue, Takahiko  Fujii, Mirei Suematsu, Shigeru Sakurai, Tetsuji Okamoto

Pages: 1875-1882 Published online on: 04 September 2014
Article

Spatial localization of the JAG1/Notch1/osteopontin cascade modulates extrahepatic metastasis in hepatocellular carcinoma

Tong-Chun Xue, Jing-Huai Zou, Rong-Xin Chen, Jie-Feng Cui, Zhao-You Tang, Sheng-Long Ye

Pages: 1883-1890 Published online on: 29 August 2014
Article

Codonolactone, a sesquiterpene lactone isolated from Chloranthus henryi Hemsl, inhibits breast cancer cell invasion, migration and metastasis by downregulating the transcriptional activity of Runx2

Wei Wang, Bin Chen, Ruolan Zou, Xiuying Tu, Songlin Tan, Hong Lu, Zhaojie Liu, Jianjiang Fu

Pages: 1891-1900 Published online on: 04 September 2014
Article

Mitochondrial division inhibitor-1 induces mitochondrial hyperfusion and sensitizes human cancer cells to TRAIL-induced apoptosis

Mamoru Akita, Miki Suzuki-Karasaki, Kyoko Fujiwara, Chinatsu Nakagawa, Masayoshi Soma, Yukihiro Yoshida, Toyoko Ochiai, Yasuaki Tokuhashi, Yoshihiro Suzuki-Karasaki

Pages: 1901-1912 Published online on: 18 August 2014
Article

Plumbagin reduces human colon cancer cell survival by inducing cell cycle arrest and mitochondria-mediated apoptosis

Binil Eldhose, Mia Gunawan, Mahbubur Rahman, Mukalel S. Latha, Vicente Notario

Pages: 1913-1920 Published online on: 08 August 2014
Article

Relative expression of hMena11a and hMenaINV splice isoforms is a useful biomarker in development and progression of human breast carcinoma

Noriyuki Tanaka, Hiroshi Yoshida, Yoshio Suzuki, Kenichi Harigaya

Pages: 1921-1928 Published online on: 08 August 2014
Article

Naringin inhibits growth and induces apoptosis by a mechanism dependent on reduced activation of NF‑κB/COX‑2‑caspase-1 pathway in HeLa cervical cancer cells

Lan Zeng, Yulan Zhen, Yiming Chen, Lin Zou, Ying Zhang, Fen Hu, Jianqiang Feng, Jianhua Shen, Bing Wei

Pages: 1929-1936 Published online on: 22 August 2014
Article

The pterocarpanquinone LQB-118 induces apoptosis in acute myeloid leukemia cells of distinct molecular subtypes and targets FoxO3a and FoxM1 transcription factors Corrigendum in /10.3892/ijo.2019.4874

Gabriela Nestal de Moraes, Carolina Pereira Castro, Eduardo Jesus Salustiano, Matheus Lourenço Dumas, Fernanda Costas, Eric Wing-Fai Lam, Paulo Roberto Ribeiro Costa, Raquel Ciuvalschi Maia

Pages: 1949-1958 Published online on: 21 August 2014
Article Open Access

Exploring breast carcinogenesis through integrative genomics and epigenomics analyses

Chin Minning, Norfilza Mohd Mokhtar, Norlia Abdullah, Rohaizak Muhammad, Nor Aina Emran, Siti Aishah Md Ali, Roslan Harun, Rahman Jamal

Pages: 1959-1968 Published online on: 27 August 2014
Article

Isoegomaketone induces apoptosis in SK-MEL-2 human melanoma cells through mitochondrial apoptotic pathway via activating the PI3K/Akt pathway

Soon-Jae Kwon, Ju-Hye Lee, Kwang-Deog Moon, Il-Yun Jeong, Sung-Tae Yee, Mi-Kyung Lee, Kwon-Il Seo

Pages: 1969-1976 Published online on: 14 August 2014
Article

Transforming growth factor-β-induced miR‑143 expression in regulation of non-small cell lung cancer cell viability and invasion capacity in vitro and in vivo

Tianli Cheng, Chengping Hu, Huaping Yang, Liming Cao, Jian An

Pages: 1977-1988 Published online on: 27 August 2014
Article

Neural stem cells preferentially migrate to glioma stem cells and reduce their stemness phenotypes

Suojun Zhang, Ruifan Xie, Tianyuan Zhao, Xiong Yang, lin Han, Fei Ye, Ting Lei, Feng Wan

Pages: 1989-1996 Published online on: 29 August 2014
Article

Postnatal Notch1 activation induces T‑cell malignancy in conditional and inducible mouse models

Ju Liu, Fengyun Dong, Iris Fung, Edwin Chen, Thaddeus  D. Allen, Urban Deutsch, Corrinne G. Lobe

Pages: 1997-2004 Published online on: 29 August 2014
Article

Clinical utility of PDSS2 expression to stratify patients at risk for recurrence of hepatocellular carcinoma

Mitsuro Kanda, Hiroyuki Sugimoto, Shuji Nomoto, Hisaharu Oya, Dai Shimizu, Hideki Takami, Ryoji Hashimoto, Fuminori Sonohara, Yukiyasu Okamura, Suguru Yamada, Tsutomu Fujii, Goro Nakayama, Masahiko Koike, Michitaka Fujiwara, Yasuhiro Kodera

Pages: 2005-2012 Published online on: 03 September 2014
Article

MicroRNA-29b-1 impairs in vitro cell proliferation, self‑renewal and chemoresistance of human osteosarcoma 3AB-OS cancer stem cells

Riccardo Di Fiore, Rosa Drago-Ferrante, Francesca Pentimalli, Domenico Di Marzo, Iris Maria Forte, Antonella D'Anneo, Daniela Carlisi, Anna De Blasio, Michela Giuliano, Giovanni Tesoriere, Antonio Giordano, Renza Vento

Pages: 2013-2023 Published online on: 22 August 2014
Article

MicroRNA-135b promotes proliferation, invasion and migration of osteosarcoma cells by degrading myocardin

Wei-Guo Xu, Ying-Lie Shang, Xian-Rui Cong, Xia Bian, Zhen Yuan

Pages: 2024-2032 Published online on: 04 September 2014
Article

E2F1 downregulation by arsenic trioxide in lung adenocarcinoma

Sze-Kwan Lam, Yuan-Yuan Li, Chun-Yan Zheng, Leanne Lee Leung, James Chung-Man Ho

Pages: 2033-2043 Published online on: 19 August 2014
Article

Effects of D-allose in combination with docetaxel in human head and neck cancer cells

Kanako Indo, Hiroshi Hoshikawa, Kazuyo Kamitori, Fuminori Yamaguchi, Terusige Mori, Masaaki Tokuda, Nozomu Mori

Pages: 2044-2050 Published online on: 08 August 2014
Article

Activated cytotoxic T-lymphocyte immunotherapy is effective for advanced oral and maxillofacial cancers

Tomoko Ohtani, Yoichi Yamada, Akifumi Furuhashi, Yukinobu Ohmura, Sayaka Nakamura, Hidefumi Kato, Kazuhiro Yoshikawa, Yoshiaki Kazaoka

Pages: 2051-2057 Published online on: 14 August 2014
Article

Tie2-dependent deletion of α6 integrin subunit in mice reduces tumor growth and angiogenesis

Claire Bouvard, Zacharie Segaoula, Adèle De Arcangelis, Isabelle Galy-Fauroux, Laetitia Mauge, Anne-Marie Fischer, Elisabeth Georges-Labouesse, Dominique Helley

Pages: 2058-2064 Published online on: 01 September 2014
Article

Sirt1 induction confers resistance to etoposide-induced genotoxic apoptosis in thyroid cancers

Ki Hwan Kweon, Cho Rok Lee, Soo Jung Jung, Eun Jeong Ban, Sang-Wook Kang, Jong Ju Jeong, Kee-Hyun Nam, Young Suk Jo, Jandee Lee, Woong Youn Chung

Pages: 2065-2075 Published online on: 08 August 2014
Article

Emodin enhances ATRA-induced differentiation and induces apoptosis in acute myeloid leukemia cells

Yingyu Chen, Jing Li, Jianda Hu, Jing Zheng, Zhihong Zheng, Tingbo Liu, Zhenxing Lin, Minhui Lin

Pages: 2076-2084 Published online on: 19 August 2014
Article

Identification of Hirsutine as an anti-metastatic phytochemical by targeting NF-κB activation

Chenghua Lou, Kei Takahashi, Tatsuro Irimura, Ikuo Saiki, Yoshihiro Hayakawa

Pages: 2085-2091 Published online on: 27 August 2014
Article

Ciprofloxacin containing Mannich base and its copper complex induce antitumor activity via different mechanism of action

Yun Fu, Yingli Yang, Sufeng Zhou, Youxun Liu, Yanbin Yuan, Shaoshan Li, Changzheng Li

Pages: 2092-2100 Published online on: 19 August 2014
Article

Epigenetic silencing of ARNTL, a circadian gene and potential tumor suppressor in ovarian cancer

Chia-Ming Yeh, Jacqueline Shay, Ting-Chuan Zeng, Jian-Liang Chou, Tim H.-M. Huang, Hung-Cheng Lai, Michael W.Y. Chan

Pages: 2101-2107 Published online on: 29 August 2014
Article

Comparative secretome analysis of cholangiocarcinoma cell line in three-dimensional culture

Phanthakarn Tit-oon, Daranee Chokchaichamnankit, Amnart Khongmanee, Phannee Sawangareetrakul, Jisnuson Svasti, Chantragan Srisomsap

Pages: 2108-2116 Published online on: 03 September 2014
Article

Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion

Nathalie Khoury, Stephany El‑Hayek, Omayr Tarras, Marwan  El‑Sabban, Mirvat El‑Sibai, Sandra Rizk

Pages: 2117-2127 Published online on: 03 September 2014
Article

Identification of a novel polyprenylated acylphloroglucinol‑derived SIRT1 inhibitor with cancer‑specific anti-proliferative and invasion-suppressing activities

lijia Zhu, Ji Qi, Christine Ya-Chi Chiao, Qiang Zhang, John A. Porco Jr, douglas V. Faller, Yan Dai

Pages: 2128-2136 Published online on: 03 September 2014
Article

Non-pegylated liposome-encapsulated doxorubicin citrate plus cyclophosphamide or vinorelbine in metastatic breast cancer not previously treated with chemotherapy: A multicenter phase III study

V. Lorusso, F. Giotta, R. Bordonaro, E. Maiello, S. Del Prete, V. Gebbia, G. Filippelli, S. Pisconti, S. Cinieri, S. Romito, F. Riccardi, R. Forcignanò, M. Ciccarese, L. Petrucelli, V. Saracino, L. I. Lupo, A. Gambino, S. Leo

Pages: 2137-2142 Published online on: 18 August 2014
Article

MicroRNA-449 suppresses proliferation of hepatoma cell lines through blockade lipid metabolic pathway related to SIRT1 Retraction in /10.3892/ijo.2023.5525

Hongyi Zhang, Zhiqiang Feng, Rui Huang, Zhenglin Xia, Guoan Xiang, Jinqian Zhang

Pages: 2143-2152 Published online on: 13 August 2014
Article

In vitro modeling of HER2-targeting therapy in disseminated prostate cancer

Jennie Andersson, Maria Rosestedt, Veronika Asplund, Nazila Yavari, Anna Orlova

Pages: 2153-2158 Published online on: 29 August 2014
Article

Effects of nutrients on matrix metalloproteinases in human T-lymphotropic virus type 1 positive and negative malignant T-lymphocytes Retraction in /10.3892/ijo.2022.5451

Steve Harakeh, Raefa Abou-Khouzam, Ghazi A. Damanhouri, Ahmed Al-Hejin, Taha Kumosani, Aleksandra Niedzwiecki, Mathias Rath, Elie Barbour, Mona Diab-Assaf, Rania Azar

Pages: 2159-2166 Published online on: 03 September 2014
Article

Sorafenib and nilotinib resensitize tamoxifen resistant breast cancer cells to tamoxifen treatment via estrogen receptor α

Astrid M. Pedersen, Susan Thrane, Anne E. Lykkesfeldt, Christina W. Yde

Pages: 2167-2175 Published online on: 22 August 2014
Journal Cover

Cover Legend PDF

November-2014
Volume 45 Issue 5

Print ISSN: 1019-6439
Online ISSN: 1791-2423

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