Journal Articles

Review Open Access

Connexin 43 in the development and progression of breast cancer: What's the connection? (Review)

Stephanie L. Phillips, Carly Bess Williams, Joelle N. Zambrano, Christina J. Williams, Elizabeth S. Yeh

Pages: 1005-1013 Published online on: 01 September 2017
Review

Trophic and neurotrophic factors in human pituitary adenomas (Review)

Marialuisa Spoletini, Samanta Taurone, Mario Tombolini, Antonio Minni, Giancarlo Altissimi, Venceslao Wierzbicki, Felice Giangaspero, Pier Paolo Parnigotto, Marco Artico, Lia Bardella, Enzo Agostinelli, Francesco Saverio Pastore

Pages: 1014-1024 Published online on: 05 September 2017
Review Open Access

Rho GTPases as therapeutic targets in cancer (Review)

G. A. Cardama, N. Gonzalez, J. Maggio, P. Lorenzano Menna, D. E. Gomez

Pages: 1025-1034 Published online on: 09 August 2017
Article Open Access

FoxM1 overexpression promotes cell proliferation and migration and inhibits apoptosis in hypopharyngeal squamous cell carcinoma resulting in poor clinical prognosis

Yan Chen, Yifei Liu, Haosheng Ni, Chuanjin Ding, Xiaobo Zhang, Zhenxin Zhang

Pages: 1045-1054 Published online on: 09 August 2017
Article Open Access

YAP signaling in gastric cancer-derived mesenchymal stem cells is critical for its promoting role in cancer progression

Zhaoji Pan, Yiqing Tian, Bin Zhang, Xu Zhang, Hui Shi, Zhaofeng Liang, Peipei Wu, Rong Li, Benshuai You, Lunyu Yang, Fei Mao, Hui Qian, Wenrong Xu

Pages: 1055-1066 Published online on: 23 August 2017
Article Open Access

Prediction of radiosensitive patients with gastric cancer by developing gene signature

Jin Zhou, Xiaoyu Wu, Gang Li, Xin Gao, Min Zhai, Weichang Chen, Huagang Hu, Zaixiang Tang

Pages: 1067-1076 Published online on: 30 August 2017
Article Open Access

Nano Let‑7b sensitization of eliminating esophageal cancer stem‑like cells is dependent on blockade of Wnt activation of symmetric division

Yamei Pang, Jian Liu, Xiang Li, Yiwen Zhang, Boxiang Zhang, Jing Zhang, Ning Du, Chongwen Xu, Rui Liang, Hong Ren, Shou-Ching Tang, Xin Sun

Pages: 1077-1088 Published online on: 29 August 2017
Article Open Access

Gold-chrysophanol nanoparticles suppress human prostate cancer progression through inactivating AKT expression and inducing apoptosis and ROS generation in vitro and in vivo

Li Lu, Ke Li, Yun-Hua Mao, Hu Qu, Bing Yao, Wen-Wen Zhong, Bo Ma, Zhong-Yang Wang

Pages: 1089-1103 Published online on: 10 August 2017
Article Open Access

SERP1 is a novel marker of poor prognosis in pancreatic ductal adenocarcinoma patients via anti-apoptosis and regulating SRPRB/NF-κB axis

Qiang Ma, Xiuxiu Wu, Jing Wu, Zhiyong Liang, Tonghua Liu

Pages: 1104-1114 Published online on: 31 August 2017
Article Open Access

TUG1 promotes osteosarcoma tumorigenesis by upregulating EZH2 expression via miR-144-3p

Jiaqing Cao, Xinyou Han, Xin Qi, Xiangyun Jin, Xiaolin Li

Pages: 1115-1123 Published online on: 30 August 2017
Article Open Access

Effect of low- and high-linear energy transfer radiation on in vitro and orthotopic in vivo models of osteosarcoma by activation of caspase-3 and -9

Eun Ho Kim, Mi-Sook Kim, Kyung-Hee Lee, Sei Sai, Youn Kyoung Jeong, Jae-Soo Koh, Chang-Bae Kong

Pages: 1124-1134 Published online on: 25 August 2017
Article Open Access

Expression of Wnt3a in hepatocellular carcinoma and its effects on cell cycle and metastasis

Caijie Lu, Yifeng He, Juan Duan, Yongguang Yang, Chunqiang Zhong, Jian Zhang, Weiguo Liao, Xiaojie Huang, Runzhi Zhu, Mingyi Li

Pages: 1135-1145 Published online on: 01 September 2017
Article

Disrupting mitochondrial Ca2+ homeostasis causes tumor-selective TRAIL sensitization through mitochondrial network abnormalities

Yohei Ohshima, Natsuhiko Takata, Miki Suzuki-Karasaki, Yukihiro Yoshida, Yasuaki Tokuhashi, Yoshihiro Suzuki-Karasaki

Pages: 1146-1158 Published online on: 11 August 2017
Article

Cx32 suppresses extrinsic apoptosis in human cervical cancer cells via the NF‑κB signalling pathway

Yongchang Lai, Lixia Fan, Yifan Zhao, Hui Ge, Xue Feng, Qin Wang, Xiaomin Zhang, Yuexia Peng, Xiyan Wang, Liang Tao

Pages: 1159-1168 Published online on: 29 August 2017
Article

Luteolin induces apoptotic cell death via antioxidant activity in human colon cancer cells

Kyoung Ah Kang, Mei Jing Piao, Yea Seong Ryu, Yu Jae Hyun, Jeong Eon Park, Kristina Shilnikova, Ao Xuan Zhen, Hee Kyoung Kang, Young Sang Koh, Yong Joo Jeong, Jin Won Hyun

Pages: 1169-1178 Published online on: 02 August 2017
Article

Expression of carbonic anhydrase IX is associated with poor prognosis through regulation of the epithelial‑mesenchymal transition in hepatocellular carcinoma

Satoshi Hyuga, Hiroshi Wada, Hidetoshi Eguchi, Toru Otsuru, Yoshifumi Iwgami, Daisaku Yamada, Takehiro Noda, Tadafumi Asaoka, Koichi Kawamoto, Kunihito Gotoh, Yutaka Takeda, Masahiro Tanemura, Koji Umeshita, Yuichiro Doki, Masaki Mori

Pages: 1179-1190 Published online on: 22 August 2017
Article

GPER promotes tamoxifen-resistance in ER+ breast cancer cells by reduced Bim proteins through MAPK/Erk-TRIM2 signaling axis

Heng Yin, Qing Zhu, Manran Liu, Gang Tu, Qing Li, Jie Yuan, Siyang Wen, Guanglun Yang

Pages: 1191-1198 Published online on: 05 September 2017
Article

Establishment of two ovarian cancer orthotopic xenograft mouse models for in vivo imaging: A comparative study

Jing Guo, Jing Cai, Yunxia Zhang, Yapei Zhu, Ping Yang, Zehua Wang

Pages: 1199-1208 Published online on: 04 September 2017
Article

Activation of the ROCK1/MMP-9 pathway is associated with the invasion and poor prognosis in papillary thyroid carcinoma

Dingyuan Luo, Haibo Chen, Xiaojuan Li, Penghui Lu, Miaoyun Long, Xinzhi Peng, Shaojian Lin, Langping Tan, Yue Zhu, Nengtai Ouyang, Honghao Li

Pages: 1209-1218 Published online on: 23 August 2017
Article

Silibinin suppresses bladder cancer cell malignancy and chemoresistance in an NF-κB signal-dependent and signal-independent manner

Yi Sun, Zhenfeng Guan, Wencai Zhao, Yazhuo Jiang, Qing Li, Yongyi Cheng, Yonggang Xu

Pages: 1219-1226 Published online on: 02 August 2017
Article

Measuring the response of human head and neck squamous cell carcinoma to irradiation in a microfluidic model allowing customized therapy

Ramsah Cheah, Rishi Srivastava, Nicholas D. Stafford, Andrew W. Beavis, Victoria Green, John Greenman

Pages: 1227-1238 Published online on: 05 September 2017
Article

Novel crosstalk between KLF4 and ZEB1 regulates gemcitabine resistance in pancreatic ductal adenocarcinoma Corrigendum in /10.3892/ijo.2020.5157

Zhiyi Wang, Yuan Chen, Yanliang Lin, Xinxing Wang, Xianping Cui, Zhenhai Zhang, Guozhe Xian, Chengkun Qin

Pages: 1239-1248 Published online on: 22 August 2017
Article Open Access

Melatonin potentiates the antitumor effect of curcumin by inhibiting IKKβ/NF-κB/COX-2 signaling pathway

Sandeep Shrestha, Jiabin Zhu, Qi Wang, Xiaohui Du, Fen Liu, Jianing Jiang, Jing Song, Jinshan Xing, Dongdong Sun, Qingjuan Hou, Yulin Peng, Jun Zhao, Xiuzhen Sun, Xishuang Song

Pages: 1249-1260 Published online on: 22 August 2017
Article

Identification of WISP1 as a novel oncogene in glioblastoma

Di Jing, Qian Zhang, Haiming Yu, Yajie Zhao, Liangfang Shen

Pages: 1261-1270 Published online on: 05 September 2017
Article

PRL-3 improves colorectal cancer cell proliferation and invasion through IL-8 mediated glycolysis metabolism

Heyang Xu, Yujie Zeng, Lu Liu, Qian Gao, Shaowen Jin, Qiusheng Lan, Wei Lai, Xingxi Luo, Heng Wu, Yongliang Huang, Zhonghua Chu

Pages: 1271-1279 Published online on: 02 August 2017
Article

Identification of novel genetic etiology and key molecular pathways for seminoma via network-based studies

Yuanlei Chen, Chao Qi, Liqun Xia, Gonghui Li

Pages: 1280-1290 Published online on: 04 August 2017
Article

Synergistic inhibitory effects on hepatocellular carcinoma with recombinant human adenovirus Aspp2 and oxaliplatin via p53-independent pathway in vitro and in vivo

Xiaoni Liu, Jianji Xu, Shuang Wang, Xiaoxiao Yu, Boxin Kou, Mengyin Chai, Yunjin Zang, Dexi Chen

Pages: 1291-1299 Published online on: 29 August 2017
Article

Expression of periostin in breast cancer cells

Katarzyna Ratajczak-Wielgomas, Jedrzej Grzegrzolka, Aleksandra Piotrowska, Rafal Matkowski, Andrzej Wojnar, Janusz Rys, Maciej Ugorski, Piotr Dziegiel

Pages: 1300-1310 Published online on: 30 August 2017
Article

Anoctamin5 regulates cell migration and invasion in thyroid cancer

Zhengyan Chang, Chunmiao Cai, Dongyan Han, Yaohui Gao, Qianyu Li, Lijin Feng, Wei Zhang, Jiayi Zheng, Jiaoying Jin, Huizhen Zhang, Qing Wei

Pages: 1311-1319 Published online on: 01 September 2017
Article

Cooperative oncogenic effect and cell signaling crosstalk of co‑occurring HER2 and mutant PIK3CA in mammary epithelial cells

Lun Dong, Fanyan Meng, Ling Wu, Allison V. Mitchell, C. James Block, Bin Zhang, Douglas B. Craig, Hyejeong Jang, Wei Chen, Qifeng Yang, Guojun Wu

Pages: 1320-1330 Published online on: 30 August 2017
Article

Ginkgetin induces G2-phase arrest in HCT116 colon cancer cells through the modulation of b‑Myb and miRNA34a expression

Yu-Jin Lee, Yeong-Rim Kang, So Young Lee, Yena Jin, Dong Cho Han, Byoung-Mog Kwon

Pages: 1331-1342 Published online on: 05 September 2017
Article

APPL1 promotes the migration of gastric cancer cells by regulating Akt2 phosphorylation

Yingxun Liu, Chunli Zhang, Lingyu Zhao, Ning Du, Ni Hou, Tusheng Song, Chen Huang

Pages: 1343-1351 Published online on: 05 September 2017
Journal Cover

Cover Legend PDF

October-2017
Volume 51 Issue 4

Print ISSN: 1019-6439
Online ISSN: 1791-2423

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