Journal Articles
Review
Hostile takeover: Manipulation of HIF-1 signaling in pathogen-associated cancers (Review)
Caixia Zhu, Qing Zhu, Chong Wang, Liming Zhang, Fang Wei, Qiliang Cai
Pages: 1269-1276 Published online on: 27 July 2016
Article
Dexamethasone downregulates expression of carbonic anhydrase IX via HIF-1α and NF-κB-dependent mechanisms
Veronika Simko, Martina Takacova, Michaela Debreova, Katarina Laposova, Elena Ondriskova-Panisova, Silvia Pastorekova, Lucia Csaderova, Jaromir Pastorek
Pages: 1277-1288 Published online on: 14 July 2016
Article
XIAP inhibits mature Smac-induced apoptosis by degrading it through ubiquitination in NSCLC
Sida Qin, Chengcheng Yang, Boxiang Zhang, Xiang Li, Xin Sun, Gang Li, Jing Zhang, Guodong Xiao, Xiao Gao, Guanghong Huang, Peili Wang, Hong Ren
Pages: 1289-1296 Published online on: 27 July 2016
Article
Cancer-associated fibroblast suppresses killing activity of natural killer cells through downregulation of poliovirus receptor (PVR/CD155), a ligand of activating NK receptor
Tomoko Inoue, Katsuyuki Adachi, Kei Kawana, Ayumi Taguchi, Takeshi Nagamatsu, Asaha Fujimoto, Kensuke Tomio, Aki Yamashita, Satoko Eguchi, Haruka Nishida, Hiroe Nakamura, Masakazu Sato, Mitsuyo Yoshida, Takahide Arimoto, Osamu Wada-Hiraike, Katsutoshi Oda, Yutaka Osuga, Tomoyuki Fujii
Pages: 1297-1304 Published online on: 26 July 2016
Article
The resveratrol analogue, 3,4,5,4'‑trans-tetramethoxystilbene, inhibits the growth of A375 melanoma cells through multiple anticancer modes of action
Vasilis P. Androutsopoulos, Irene Fragiadaki, Demetrios A. Spandidos, Androniki Tosca
Pages: 1305-1314 Published online on: 28 July 2016
Article
Radiofrequency radiation at Stockholm Central Railway Station in Sweden and some medical aspects on public exposure to RF fields
Lennart Hardell, Tarmo Koppel, Michael Carlberg, Mikko Ahonen, Lena Hedendahl
Pages: 1315-1324 Published online on: 12 August 2016
Article
MicroRNA-107 inhibits tumor growth and metastasis by targeting the BDNF-mediated PI3K/AKT pathway in human non-small lung cancer Retraction in /10.3892/ijo.2021.5246
Huan Xia, Yang Li, Xiaohong Lv
Pages: 1325-1333 Published online on: 25 July 2016
Article
RNase activity of sialic acid-binding lectin from bullfrog eggs drives antitumor effect via the activation of p38 MAPK to caspase-3/7 signaling pathway in human breast cancer cells
Yukiko Kariya, Takeo Tatsuta, Shigeki Sugawara, Yoshinobu Kariya, Kazuo Nitta, Masahiro Hosono
Pages: 1334-1342 Published online on: 11 August 2016
Article
CD44 correlates with clinicopathological characteristics and is upregulated by EGFR in breast cancer
Hanxiao Xu, Kongju Wu, Yijun Tian, Qian Liu, Na Han, Xun Yuan, Lu Zhang, Gen Sheng Wu, Kongming Wu
Pages: 1343-1350 Published online on: 29 July 2016
Article
Iron depletion-induced downregulation of N-cadherin expression inhibits invasive malignant phenotypes in human esophageal cancer
Seishi Nishitani, Kazuhiro Noma, Toshiaki Ohara, Yasuko Tomono, Shinichiro Watanabe, Hiroshi Tazawa, Yasuhiro Shirakawa, Toshiyoshi Fujiwara
Pages: 1351-1359 Published online on: 29 July 2016
Article
The EGFR pathway is involved in the regulation of PD-L1 expression via the IL-6/JAK/STAT3 signaling pathway in EGFR-mutated non-small cell lung cancer
Nan Zhang, Yuanyuan Zeng, Wenwen Du, Jianjie Zhu, Dan Shen, Zeyi Liu, Jian-An Huang
Pages: 1360-1368 Published online on: 26 July 2016
Article
Increased expression levels of ppGalNAc-T13 in lung cancers: Significance in the prognostic diagnosis
Kenichi Nogimori, Tomoko Hori, Koji Kawaguchi, Takayuki Fukui, Shinji Mii, Hiroshi Nakada, Yasuyuki Matsumoto, Yoshio Yamauchi, Masahide Takahashi, Keiko Furukawa, Okajima Tetsuya, Kohei Yokoi, Yoshinori Hasegawa, Koichi Furukawa
Pages: 1369-1376 Published online on: 29 July 2016
Article
Enhancement of active MMP release and invasive activity of lymph node metastatic tongue cancer cells by elevated signaling via the TNF-α-TNFR1-NF-κB pathway and a possible involvement of angiopoietin-like 4 in lung metastasis
Takuya Tanaka, Takahisa Imamura, Masakazu Yoneda, Atsushi Irie, Hidenao Ogi, Masashi Nagata, Ryoji Yoshida, Daiki Fukuma, Kenta Kawahara, Masanori Shinohara, Hideki Nakayama
Pages: 1377-1384 Published online on: 10 August 2016
Article
Cell division cycle associated 1 as a novel prognostic biomarker and therapeutic target for oral cancer
Phung Manh Thang, Atsushi Takano, Yoshihiro Yoshitake, Masanori Shinohara, Yoshinori Murakami, Yataro Daigo
Pages: 1385-1393 Published online on: 05 August 2016
Article
SPARC overexpression combined with radiation retards angiogenesis by suppressing VEGF-A via miR‑410 in human neuroblastoma cells
Jerusha Boyineni, Smita Tanpure, Manu Gnanamony, Reuben Antony, Karen S. Fernández, Julian Lin, David Pinson, Christopher S. Gondi
Pages: 1394-1406 Published online on: 03 August 2016
Article
AMP-activated protein kinase activator, HL156A reduces thioacetamide-induced liver fibrosis in mice and inhibits the activation of cultured hepatic stellate cells and macrophages
Hye Shin Lee, Hyun-Sang Shin, Jinhyeok Choi, Sung-Jin Bae, Hee-Jun Wee, Taekwon Son, Ji Hae Seo, Ji-Hyeon Park, Sung-Wuk Kim, Kyu-Won Kim
Pages: 1407-1414 Published online on: 21 July 2016
Article
Prognostic value of pigment epithelium-derived factor for neoadjuvant radiation therapy in patients with locally advanced rectal carcinoma
Haizhao Yi, Dengbo Ji, Tiancheng Zhan, Yunfeng Yao, Ming Li, Jinying Jia, Zhaowei Li, Jin Gu
Pages: 1415-1426 Published online on: 12 July 2016
Article
β-Elemene enhances the efficacy of gefitinib on glioblastoma multiforme cells through the inhibition of the EGFR signaling pathway
Lin Mu, Tianjiao Wang, Yanwei Chen, Xinqiang Tang, Yuhui Yuan, Yongshun Zhao
Pages: 1427-1436 Published online on: 21 July 2016
Article
MicroRNA-186 suppresses cell proliferation and metastasis through targeting MAP3K2 in non-small cell lung cancer
Tonghai Huang, Kelin She, Guilin Peng, Wei Wang, Jun Huang, Jingpei Li, Zheng Wang, Jianxing He
Pages: 1437-1444 Published online on: 29 July 2016
Article
α-Lipoic acid sensitizes lung cancer cells to chemotherapeutic agents and anoikis via integrin β1/β3 downregulation
Punyawee Puchsaka, Chatchai Chaotham, Pithi Chanvorachote
Pages: 1445-1456 Published online on: 18 July 2016
Article
The novel model peptide, αAL14, regulates angiogenesis by inhibiting VEGFR 2-mediated signaling in HUVECs
Nan-Hee Kim, Chang-Won Kang, Hye-Jin Go, Chan-Hee Kim, Nam Gyu Park, Gun-Do Kim
Pages: 1457-1468 Published online on: 09 August 2016
Article
Metabotropic glutamate receptor 3 is involved in B-cell-related tumor apoptosis
Xiaoling Liu, Yu Zhang, Zhiding Wang, Xiaoqian Wang, Gaizhi Zhu, Gencheng Han, Guojiang Chen, Chunmei Hou, Tianxiao Wang, Beifen Shen, Yan Li, Ning Ma, He Xiao, Renxi Wang
Pages: 1469-1478 Published online on: 15 July 2016
Article
The resveratrol analog HS-1793 enhances radiosensitivity of mouse-derived breast cancer cells under hypoxic conditions
Yoo Jin Choi, Kyu Heo, Hee Sung Park, Kwang Mo Yang, Min Ho Jeong
Pages: 1479-1488 Published online on: 03 August 2016
Article
Abnormal expression of FOSB correlates with tumor progression and poor survival in patients with gastric cancer
Chong Tang, Yasu Jiang, Weiwei Shao, Wen Shi, Xuesong Gao, Weiyan Qin, Tian Jiang, Feiran Wang, Shichun Feng
Pages: 1489-1496 Published online on: 18 August 2016
Article
Tricin, 4',5,7-trihydroxy-3',5'-dimethoxyflavone, exhibits potent antiangiogenic activity in vitro
Jang Mi Han, Ho Jeong Kwon, Hye Jin Jung
Pages: 1497-1504 Published online on: 03 August 2016
Article
Downregulation of RLIP76 is associated with vincristine resistance in human colorectal cancer HCT-8/VCR cells
Wenwen Wang, Juan Liu, Jianni Qi, Junyong Zhang, Qiang Zhu, Jincai Ma, Chengyong Qin
Pages: 1505-1512 Published online on: 23 August 2016
Article
Inhibitory effect of bufalin combined with Hedgehog signaling pathway inhibitors on proliferation and invasion and metastasis of liver cancer cells
Xia Sheng, Xiaoting Sun, Kang Sun, Hua Sui, Jianmin Qin, Qi Li
Pages: 1513-1524 Published online on: 22 August 2016
Article
Honokiol inhibits migration of renal cell carcinoma through activation of RhoA/ROCK/MLC signaling pathway
Shujie Cheng, Victor Castillo, Matt Welty, Isaac Eliaz, Daniel Sliva
Pages: 1525-1530 Published online on: 19 August 2016
Article
MicroRNA-7 inhibits proliferation, migration and invasion of thyroid papillary cancer cells via targeting CKS2
Kaiyao Hua, Jiali Jin, Huiwen Zhang, Bingkun Zhao, Chenyang Wu, Hui Xu, Lin Fang
Pages: 1531-1540 Published online on: 18 August 2016
Article
Association and regulation of protein factors of field effect in prostate tissues
Kristin N. Gabriel, Anna C. Jones, Julie P.T. Nguyen, Kresta S. Antillon, Sara N. Janos, Heidi N. Overton, Shannon M. Jenkins, Emily H. Frisch, Kristina A. Trujillo, Marco Bisoffi
Pages: 1541-1552 Published online on: 22 August 2016
Article
Effect of resveratrol on cancer progression through the REG Ⅲ expression pathway in head and neck cancer cells
Shinji Mikami, Ichiro Ota, Takashi Masui, Asako Itaya‑Hironaka, Ryogo Shobatake, Hideyuki Okamoto, Shin Takasawa, Tadashi Kitahara
Pages: 1553-1560 Published online on: 19 August 2016
Article
A novel polysaccharide derived from algae extract induces apoptosis and cell cycle arrest in human gastric carcinoma MKN45 cells via ROS/JNK signaling pathway
Peiyu Xie, Isao Fujii, Jien Zhao, Makoto Shinohara, Makoto Matsukura
Pages: 1561-1568 Published online on: 18 August 2016
Article
c-Myc modulates glucose metabolism via regulation of miR-184/PKM2 pathway in clear-cell renal cell carcinoma
Jiwei Huang, Wen Kong, Jin Zhang, Yonghui Chen, Wei Xue, Dongming Liu, Yiran Huang
Pages: 1569-1575 Published online on: 14 July 2016
Article
Autophagic degradation of epidermal growth factor receptor in gefitinib-resistant lung cancer by celastrol
Su-Wei Xu, Betty Yuen Kwan Law, Simon Wing Fai Mok, Elaine Lai Han Leung, Xing Xing Fan, Paolo Saul Coghi, Wu Zeng, Chung-Hang Leung, Dik-Lung Ma, Liang Liu, Vincent Kam Wai Wong
Pages: 1576-1588 Published online on: 03 August 2016
Article
Upregulation of microRNA-370 promotes cell apoptosis and inhibits proliferation by targeting PTEN in human gastric cancer
Yang Zeng, Meng Fu, Gang-Wei Wu, An-Zu Zhang, Jin-Ping Chen, Hong-Yue Lin, Yong-An Fu, Jing Jia, Zong-Da Cai, Xiao-Jian Wu, Ping Lan
Pages: 1589-1599 Published online on: 02 August 2016
Article
Deficiency of 53BP1 inhibits the radiosensitivity of colorectal cancer
Yong Xiao, Xiumei Zheng, Ai Huang, Tao Liu, Tao Zhang, Hong Ma
Pages: 1600-1608 Published online on: 25 July 2016
Article
Sulforaphane increases the efficacy of anti-androgens by rapidly decreasing androgen receptor levels in prostate cancer cells
Namrata Khurana, Sudha Talwar, Partha K. Chandra, Pankaj Sharma, Asim B. Abdel-Mageed, Debasis Mondal, Suresh C. Sikka
Pages: 1609-1619 Published online on: 02 August 2016
Article
Transcriptional regulation of E-cadherin by small activating RNA: A new double-stranded RNA
Zhiming Wu, Yan Li, Zhiyong Li, Zhuowei Liu, Zike Qin, Xiangdong Li, Yunlin Ye, Lei Bu, Bin Lin, Zhanyu Wang, Guojin Jia, Gang Chen
Pages: 1620-1628 Published online on: 03 August 2016
Article
miR-449 overexpression inhibits papillary thyroid carcinoma cell growth by targeting RET kinase-β-catenin signaling pathway
Zongyu Li, Xin Huang, Jinkai Xu, Qinghua Su, Jun Zhao, Jiancang Ma
Pages: 1629-1637 Published online on: 18 August 2016
Article
Caudatin targets TNFAIP1/NF-κB and cytochrome c/caspase signaling to suppress tumor progression in human uterine cancer
Zhi-Wen Tan, Shun Xie, Si-Yang Hu, Tao Liao, Pan Liu, Ke-Hong Peng, Xin-Zhou Yang, Zhi-Li He, Hong-Yan Tang, Yuan Cui, Xiao-Ning Peng, Jian Zhang, Chang Zhou
Pages: 1638-1650 Published online on: 19 August 2016
Article
Identification of proteomic and metabolic signatures associated with chemoresistance of human epithelial ovarian cancer
Wenjuan Wu, Qi Wang, Fuqiang Yin, Zhijun Yang, Wei Zhang, Hani Gabra, Li Li
Pages: 1651-1665 Published online on: 10 August 2016
Article
Triiodothyronine regulates cell growth and survival in renal cell cancer
Anna M. Czarnecka, Damian Matak, Lukasz Szymanski, Karolina H. Czarnecka, Slawomir Lewicki, Robert Zdanowski, Ewa Brzezianska-Lasota, Cezary Szczylik
Pages: 1666-1678 Published online on: 23 August 2016
Article
Silencing of CDC20 suppresses metastatic castration-resistant prostate cancer growth and enhances chemosensitivity to docetaxel
Ke Li, Yunhua Mao, Li Lu, Cheng Hu, Dejuan Wang, Jie Si-Tu, Minhua Lu, Shubin Peng, Jianguang Qiu, Xin Gao
Pages: 1679-1685 Published online on: 23 August 2016
Article
Prolonged survival in hepatocarcinoma patients with increased regucalcin gene expression: HepG2 cell proliferation is suppressed by overexpression of regucalcin in vitro
Masayoshi Yamaguchi, Satoru Osuka, M. Neale Weitzmann, Bassel F. El-Rayes, Mamoru Shoji, Tomiyasu Murata
Pages: 1686-1694 Published online on: 23 August 2016
Article
Genome-wide profiling of long non-coding RNA expression patterns in anthracycline-resistant breast cancer cells
Dong-Xu He, Guang-Yuan Zhang, Xiao-Ting Gu, Ai-Qin Mao, Chun-Xiao Lu, Jian Jin, De-Quan Liu, Xin Ma
Pages: 1695-1703 Published online on: 22 August 2016
Article
Tetramethypyrazine inhibits renal cell carcinoma cells through inhibition of NKG2D signaling pathways
Yun Luan, Junli Liu, Xiaoli Liu, Xia Xue, Feng Kong, Chao Sun, Jue Wang, Ling Liu, Hongying Jia
Pages: 1704-1712 Published online on: 23 August 2016
Article
Peridinin, a carotenoid, inhibits proliferation and survival of HTLV-1-infected T-cell lines
Chie Ishikawa, Takahiro Jomori, Junichi Tanaka, Masachika Senba, Naoki Mori
Pages: 1713-1721 Published online on: 04 August 2016
Article
L1-CAM knock-down radiosensitizes neuroblastoma IMR-32 cells by simultaneously decreasing MycN, but increasing PTEN protein expression
Johnny Rached, Zeina Nasr, Jad Abdallah, Tamara Abou-Antoun
Pages: 1722-1730 Published online on: 18 July 2016
Article
Hypoxia upregulates Malat1 expression through a CaMKK/AMPK/HIF-1α axis
Sandrine Sallé-Lefort, Stéphanie Miard, Marc-André Nolin, Louise Boivin, Marie-Ève Paré, Richard Debigaré, Frédéric Picard
Pages: 1731-1736 Published online on: 25 July 2016
Article
EBP50 interacts with EGFR and regulates EGFR signaling to affect the prognosis of cervical cancer patients
Zhiqiang Peng, Qiqi Wang, Yue Zhang, Junqi He, Junfang Zheng
Pages: 1737-1745 Published online on: 11 August 2016
Article
Fluoxetine regulates cell growth inhibition of interferon-α
Yu-Min Lin, Bu-Chin Yu, Wen-Tai Chiu, Hung-Yu Sun, Yu-Chieh Chien, Hui-Chen Su, Shu-Yang Yen, Hsin-Wen Lai, Chyi-Huey Bai, Kung-Chia Young, Chiung-Wen Tsao
Pages: 1746-1754 Published online on: 05 August 2016
Article
Development of a robust DNA quality and quantity assessment qPCR assay for targeted next-generation sequencing library preparation
Jennifer Dang, Pedro Mendez, Sharon Lee, James W. Kim, Jun-Hee Yoon, Thomas W. Kim, Charles J. Sailey, David M. Jablons, Il-Jin Kim
Pages: 1755-1765 Published online on: 11 August 2016
Correction
