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Experimental and Therapeutic Medicine
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December-2024 Volume 28 Issue 6

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Impact Factor: 2.3

Review Open Access

Saharan dust and respiratory health: Understanding the link between airborne particulate matter and chronic lung diseases (Review)

Vasiliki Epameinondas Georgakopoulou, Chrysoula Taskou, Athina Diamanti, Despoina Beka, Petros Papalexis, Nikolaos Trakas, Demetrios A. Spandidos
Article Number: 460
Published online on: 22 October 2024

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Review Open Access

Neural repair function of osteopontin in stroke and stroke‑related diseases (Review)

Xin Sun, Chunhao Li
Article Number: 459
Published online on: 16 October 2024

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Article Open Access

Efficacy of mechanical against manual method in cardiopulmonary resuscitation for out‑of‑hospital cardiac arrest: A meta‑analysis

Xinqing Zhu, Jun Fu
Article Number: 458
Published online on: 16 October 2024

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Article Open Access

Prognostic value of Ki67 in phyllodes tumor of the breast: A systematic review and meta‑analysis

Fahd Refai
Article Number: 457
Published online on: 15 October 2024

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Article Open Access

Formononetin suppresses the malignant progression of papillary thyroid carcinoma depending on downregulation of CBX4

Hongbo Yu, Ji Qu, Haixin Gou, Ying Zhou
Article Number: 456
Published online on: 15 October 2024

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Article Open Access

Characteristics of different pathogenic bacterial infections and their effects on prognosis in adult patients with bronchiectasis

Yueying Niu, Xue Lian, Xiaosi Li, Xiang Ge, Haiqin Wang
Article Number: 455
Published online on: 14 October 2024

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Review Open Access

Complex interplays: Asthma management and maternal‑fetal outcomes in pregnancy (Review)

Vasiliki Epameinondas Georgakopoulou, Chrysoula Taskou, Demetrios A. Spandidos, Athina Diamanti
Article Number: 454
Published online on: 11 October 2024

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Review Open Access

Diapedesis leading to hematidrosis due to abrupt emotional suffering (Review)

Dimitrios Anyfantakis, Gregory Tsoucalas, Andreas Karelis, Nikolaos Papazoglou, Demetrios A. Spandidos, Konstantinos Krasagakis, Emmanouil Symvoulakis
Article Number: 453
Published online on: 11 October 2024

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Case Report

Meningioma‑associated parkinsonism related to basal ganglia and cerebellar motor circuits: A case report and literature review

Shintaro Takeda, Shohei Nagasaka, Kohei Suzuki, Koichiro Futatsuya, Junkoh Yamamoto
Article Number: 452
Published online on: 09 October 2024

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Article Open Access

Role of vitamin D in prevention of type 2 diabetes mellitus: A systematic review and meta‑analysis

Gyuri Sim, Yunjung Kim, Sun Min Lee, Jongsung Hahn, Jongyoon Kim
Article Number: 451
Published online on: 08 October 2024

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Retraction Open Access

[Retracted] Role of long non‑coding RNA MALAT1 in chronic obstructive pulmonary disease

Tian-Jun Hu, Hong-Bo Huang, Hai-Bo Shen, Wei Chen, Zhen-Hua Yang
Article Number: 450
Published online on: 07 October 2024

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Article

Implanted cartilaginous grafts following rhinoplasty: A retrospective histopathological study

Susumu Matsukuma, Ayano Matsunaga, Sho Ogata
Article Number: 449
Published online on: 03 October 2024

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Article Open Access

Duloxetine for individuals with chronic back pain: A systematic review and meta‑analysis of randomized controlled trials

Duaa Bafail, Hazem E. Mohammed, Zeyad Bady, Ahmed Zaki Akl, Mohamed S.A. Shehata
Article Number: 448
Published online on: 03 October 2024

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Article Open Access

Peimine induces apoptosis of glioblastoma cells through regulation of the PI3K/AKT signaling pathway

Jiaming Lei, Jianbao Yang, Shijiao Cheng, Feifei Lu, Zihan Wu, Ziyi Wang, Ziqi Wang, Chenyu Sun, Li Lin
Article Number: 447
Published online on: 03 October 2024

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Article Open Access

Low frequency‑pulsed electromagnetic fields promote osteogenic differentiation of bone marrow‑derived mesenchymal stem cells by regulating connexin 43 expression

Zhi-Jun Lu, Hou-Yun Gu, Zhi-Qiang Li, Fei-Xiang Lin
Article Number: 446
Published online on: 01 October 2024

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Article Open Access

Nasal allergen and methacholine provocation tests influence co‑expression patterns of TGF‑β/SMAD and MAPK signaling pathway genes in patients with asthma

Jacek Plichta, Alicja Majos, Piotr Kuna, Michał Panek
Article Number: 445
Published online on: 01 October 2024

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Retraction Open Access

[Retracted] 3,4‑Dihydroxyphenylethanol alleviates early brain injury by modulating oxidative stress and Akt and nuclear factor‑κB pathways in a rat model of subarachnoid hemorrhage

Peng Fu, Quan Hu
Article Number: 444
Published online on: 30 September 2024

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Case Report Open Access

Management of bronchopleural fistula after microwave ablation of lung tumor: A case report and literature review

Xiaopeng Meng, Miao Qiu, Liyong Hu, Jianfang Zhu
Article Number: 443
Published online on: 30 September 2024

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Case Report Open Access

Pulsed field ablation for paroxysmal atrial fibrillation with mitral and cavotricuspid isthmus‑dependent atrial flutter: A case report

Jialing He, Zhen Zhang, Guoshu Yang, Duan Luo, Shiqiang Xiong, Yongxin Yang, Guijun He, Hanxiong Liu
Article Number: 442
Published online on: 27 September 2024

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Article Open Access

Overexpression of ELF1 combined with MMP9 is associated with prognosis and tumor microenvironment in gastric cancer

Xiaoxia Zhang, Xiaoyan Ren, Shu Zhang, Yan Wang
Article Number: 441
Published online on: 27 September 2024

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Article Open Access

Identification and validation of autophagy‑related genes in hypertrophic cardiomyopathy

Rong-Bin Qiu, Shi-Tao Zhao, Zhi-Wei Li, Rui-Yuan Zeng, Zhi-Cong Qiu, Han-Zhi Peng, Zhi-Qiang Xu, Lian-Fen Zhou, Song-Qing Lai, Li Wan
Article Number: 440
Published online on: 25 September 2024

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Review Open Access

Exosomes are the mediators between the tumor microenvironment and prostate cancer (Review)

Yiqi Wu, Xiao Wang, Yan Zeng, Xiuheng Liu
Article Number: 439
Published online on: 25 September 2024

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Case Report Open Access

Personalized subperiosteal implant‑supported obturator for the rehabilitation of rhino‑orbit‑cerebral mucormycosis sequela: A case report

Julia Parras‑Hernández, Álvaro Tofé‑Povedano, Javier Herce‑López, David Matute‑García, Elena Martínez‑Carapeto, Guadalupe Cuadrado‑Caballero, Ángel Rollón‑Mayordomo
Article Number: 438
Published online on: 25 September 2024

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Retraction Open Access

[Retracted] Electroacupuncture attenuates cervical spinal cord injury following cerebral ischemia/reperfusion in stroke‑prone renovascular hypertensive rats

Feng Tan, Jie Chen, Yangui Liang, Minhua Gu, Yanping Li, Xuewen Wang, Di Meng
Article Number: 437
Published online on: 24 September 2024

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Article Open Access

TLR2 promotes traumatic deep venous thrombosis of the lower extremity following femoral fracture by activating the NF‑κB/COX‑2 signaling pathway in rats

Tianting Guo, Lijiao Xiong, Junbin Xie, Jiwei Zeng, Zhihua Huang, Mengting Yao, Xiaoan Zhang, Jianwen Mo
Article Number: 436
Published online on: 20 September 2024

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Case Report Open Access

Treatment and management of duodenal gangliocytic paraganglioma: A case report

Na Xiao, Sumin Zhu, Huan Liu, Longfei Li, Lihong Shi
Article Number: 435
Published online on: 19 September 2024

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Case Report

Ischemic fasciitis in a mobile elderly patient: A case report

Ayano Matsunaga, Yae Sasaki, Sho Ogata, Shogo Kariya, Michiro Susa, Susumu Matsukuma
Article Number: 434
Published online on: 19 September 2024

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Article Open Access

Transcriptomic analysis and validation study of key genes and the HIF‑1α/HO‑1 pathway associated with ferroptosis in neutrophilic asthma

Lu Lin, Zenghua Liao, Yinghua Li, Shitong Pan, Sihui Wu, Qi-Xiang Sun, Chaoqian Li
Article Number: 433
Published online on: 19 September 2024

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Article Open Access

Identification of potential characteristic genes in chronic skin infections through RNA sequencing and immunohistochemical analysis

Hongying Cao, Wei Xiong, Mei Zeng, Li Hu, Yan Xu, Wu Zhong, Yingchun Hu
Article Number: 432
Published online on: 18 September 2024

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Retraction Open Access

[Retracted] Application of a novel targeting nanoparticle contrast agent combined with magnetic resonance imaging in the diagnosis of intraductal papillary mucinous neoplasm

Min Sun, Liqing Kang, Yanchao Cui, Guoce Li
Article Number: 431
Published online on: 18 September 2024

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Journal Cover
March-2026 Volume 31 Issue 3

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Impact Factor: 2.3

Article Open Access

Effect of SGLT2 inhibitors on heart failure outcomes in patients with and without diabetes: A systematic review and meta‑analysis of randomized controlled trials

Duaa Abdullah Bafail, Noura Hamdi Alhalees
Article Number: 84
Published online on: 28 January 2026

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Article Open Access

Exploring the protective mechanisms and therapeutic potential of carnosic acid against acute respiratory distress syndrome through molecular docking, molecular dynamics and experimental verification

Quan Li, Lili Ding, Haijun Sun, Weichao Ding, Mengmeng Wang, Zhaorui Sun, Congxue Ma
Article Number: 83
Published online on: 28 January 2026

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Review

Exploring the roots of schizophrenia: Current research and future directions (Review)

Shuang Lv, Chunxia Luo
Article Number: 82
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] miR‑146a‑5p protects against renal injury in MRL/lpr mice via improvement of the Treg/Th17 imbalance by targeting the TRAF6/NF‑κB axis

Jiajia Teng, Feng Yang, Xiaoling Li
Article Number: 81
Published online on: 28 January 2026

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Retraction Open Access

[Retracted] MicroRNA‑24‑3p inhibition prevents cell growth of vascular smooth muscle cells by targeting Bcl‑2‑like protein 11

Huanxin Zhang, Shizhen Xue, Yi Feng, Jun Shen, Jixian Zhao
Article Number: 80
Published online on: 26 January 2026

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Article Open Access

Efficacy and safety of unilateral biportal endoscopy vs. percutaneous endoscopic interlaminar approach in lumbar disc herniation: A meta‑analysis​

Yuhao Gao, Fangzheng He, Ji Wen, Shilei Qin, Pengfei Han, Yunfeng Xu
Article Number: 79
Published online on: 23 January 2026

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Case Report Open Access

Intralobar pulmonary sequestration coexisting with pulmonary cryptococcosis: A case report and literature review

Dan Cheng, Yue Wang, Jun Li, Dan Yu, Yunyun Wang, Jinbo Fan, Jiankun Wang, Liqun He
Article Number: 78
Published online on: 23 January 2026

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Article Open Access

Tumor‑associated macrophages suppress estrogen receptor‑β expression in triple‑negative breast cancer through the PI3K/AKT pathway

Qiulei Zhang, Di Guo, Gaoran Xu, Rong Xie, Yuqing Deng, Peng Fu, Jinnan Wan
Article Number: 77
Published online on: 21 January 2026

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Article Open Access

Development of a diagnostic model for esophageal achalasia assessed by esophageal high‑resolution manometry using artificial intelligence

Maiko Tabuchi, Yasuhiko Nakao, Hitomi Minami, Hiroko Inomata, Junya Shiota, Taro Akashi, Keiichi Hashiguchi, Moto Kitayama, Kayoko Matsushima, Naoyuki Yamaguchi, Yuko Akazawa, Hisamitsu Miyaaki
Article Number: 76
Published online on: 21 January 2026

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Case Report

Use of metagenomic next‑generation sequencing to diagnose Tropheryma whipplei infection‑related pneumonia: A case report

Yutu Luo, Haibing Ding, Jiahua Pan, Guangyang Xu
Article Number: 75
Published online on: 21 January 2026

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Article Open Access

Effect of rivaroxaban on DNA damage in an ischemia-reperfusion model: Evaluation of 8‑OHdG levels

Ceren Sayarer, Abidin Cenk Erdal, Tuğra Gençpinar, Özlem Gürsoy Doruk, Tuncay Küme
Article Number: 74
Published online on: 21 January 2026

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Correction Open Access

[Corrigendum] Hepatoprotective activity of chrysin is mediated through TNF‑α in chemically‑induced acute liver damage: An in vivo study and molecular modeling 

Anca Hermenean, Teodora Mariasiu, Inmaculada Navarro-González, Josefina Vegara-Meseguer, Eftimie Miuțescu, Sandipan Chakraborty, Horacio Pérez-Sánchez
Article Number: 73
Published online on: 21 January 2026

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Retraction Open Access

[Retracted] Gambogic acid suppresses colon cancer cell activity in vitro

Zailong Zhou, Jian Ma
Article Number: 72
Published online on: 19 January 2026

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Case Report

Identification of a novel KISS1R (GPR54) gene variant (c.505+2T>G) in a patient with congenital hypogonadotropic hypogonadism: A case report and literature review

Burak Menekse, Enes Ucgul, Abdullatif Bakir, Sema Hepsen, Ilknur Ozturk Unsal, Muhammed Kizilgul, Takako Araki, Erman Cakal
Article Number: 71
Published online on: 16 January 2026

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Case Report Open Access

Postoperative hypofractionated intensity-modulated proton therapy to control recurrent paraganglioma at the jugular foramen: A case report and literature review

Wei Wang, Yingxia Yuan, Jiwei Bai, Yue Zou, Dongxue Zhou, Jun Zhao, Shuyan Zhang, Zishen Wang, Jie Wang, Jingjing Kong, Lu Yang, Masashi Mizumoto, Hideyuki Sakurai, Shosei Shimizu
Article Number: 70
Published online on: 16 January 2026

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Article

Serum antithrombin III level predicts acute kidney injury in patients with traumatic brain injury

Ruoran Wang, Min He, Jianguo Xu
Article Number: 69
Published online on: 16 January 2026

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Retraction Open Access

[Retracted] β‑asarone relieves chronic unpredictable mild stress induced depression by regulating the extracellular signal‑regulated kinase signaling pathway

Haiying Dong, Weiliang Cong, Xiwen Guo, Yuhua Wang, Shengju Tong, Qiang Li, Chengchong Li
Article Number: 68
Published online on: 12 January 2026

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Case Report Open Access

Rare co‑occurrence of gastrointestinal stromal tumors and leiomyomas: A case report and review of the literature

Yu Zhang, Xiaoqiong Shi, Wenfu Xie, Meilin He, Shan Zhang, Xue Peng, Hao Lei, Xulei Li, Haiying Liu, Qiao Shu, Fangyuan Zou, Mingyong Wei
Article Number: 67
Published online on: 09 January 2026

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Article Open Access

No increased risk of hepatic enzyme abnormalities with non‑peptidic thrombopoietin receptor agonists in immune thrombocytopenia: A meta‑analysis of randomized controlled trials

Nan Shen, Rang Wu, Tiantian Lu, Song Liu, Yazhou Jiang, Jingjing Yan, Tao Ning, Chang Dong, Jianqin Li, Suyue Zhu
Article Number: 66
Published online on: 09 January 2026

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Case Report

Submucosal colonic fecalith mimicking a submucosal malignant tumor at the anastomotic site after colon cancer: A case report

Motoaki Yuhi, Masatsugu Hiraki, Shin Takesue, Mariko Hashiguchi, Megumi Nishiyama, Yoshiaki Egashira, Tatsuya Manabe, Hirokazu Noshiro
Article Number: 65
Published online on: 08 January 2026

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Article

Clinical characteristics of acute primary angle closure following COVID‑19 during the Omicron outbreak in China

Jianhui Zhang, Yingying Xue, Liu Zhang, Yuhong Wang, Shancheng Si
Article Number: 64
Published online on: 09 January 2026

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Retraction Open Access

[Retracted] Aberrant expression and mechanism of miR‑130b‑3p/phosphatase and tensin homolog in nephroblastoma in children

Yifeng Hu, Jingtie Yan
Article Number: 63
Published online on: 05 January 2026

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Case Report Open Access

Novel variants in STAG2 and PKD1 associate with multiple congenital malformations and autosomal dominant polycystic kidney disease in a Chinese family: A case report and literature review

Qi Yang, Qiang Zhang, Sheng Yi, Xunzhao Zhou, Yiyan Ruan, Shujie Zhang, Shang Yi, Qinle Zhang, Zailng Qin, Jingsi Luo
Article Number: 62
Published online on: 30 December 2025

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Journal Cover
April-2026 Volume 31 Issue 4

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Impact Factor: 2.3

Case Report

Sagittal sinus thrombosis in pregnancy: A case report

Zaheera Saadia, Misbah Ilyas, Jayd Saud Althwiny, Fai Alaqel, Alanoud Abdullah Alsufayri, Lujain Husain Almutairi
Article Number: 100
Published online on: 05 February 2026

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Article

Elevated PGE2 and COX‑2 expression in villous adenoma: Implications for electrolyte depletion syndrome

Shiki Fujino, Hiroyuki Fukuda, Katsuki Danno, Takashi Takeda, Masaya Higashiguchi, Kozo Noguchi, Takefumi Hirao, Aya Ito, Norikatsu Miyoshi, Yoshio Oka
Article Number: 99
Published online on: 04 February 2026

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Article Open Access

Wogonin as a potential therapeutic agent for psoriasis: Core target identification and validation

Yu Lu, Xiaomei Zhou, Yiyu Guo, Fengrui Zhang, Jirong Wang, Jinhong Ge, Yan Xiao, Dengke Yang
Article Number: 98
Published online on: 04 February 2026

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Expression of Concern Open Access

[Expression of Concern] Glibenclamide exacerbates adriamycin‑induced cardiotoxicity by activating oxidative stress‑induced endoplasmic reticulum stress in rats

Meng-Lin Liu, Meng-Long Wang, Jing-Jun Lv, Jie Wei, Jun Wan
Article Number: 97
Published online on: 04 February 2026

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Review

Key role of the autonomic nervous system in breast cancer (Review)

Min Wu, Zhiwu Zhang, Lu Zhou, Shiqi Liu, Qing Chen, Cui Guo, Shasha Zhao, Xuedan Chen
Article Number: 96
Published online on: 04 February 2026

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Review Open Access

Senescent hepatic stellate cells drive inflammation and disease progression in MASH (Review)

Zhiqi Han, Yiran She, Di Wu, Nuo Zhang, Zheyuan Liu, Zhongyuan Wang, Xiaoying Zhou, Shuo Li
Article Number: 95
Published online on: 04 February 2026

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Article Open Access

PUM2 knockdown regulates the expression and alternative splicing of genes associated with myocardial fibrosis in H9C2 cells

Zilong Zhang, Hangyu Zhou, Diliyaer Adili, Wei Zhu, Yong Liu, Wenzheng Zhou, Zhao Wang, Jie Li
Article Number: 94
Published online on: 04 February 2026

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Case Report

A novel human papillomavirus‑induced ‘doughnut wart’ lesion treated with 5‑aminolevulinic acid photodynamic therapy: A case report

Ke Li, Yitao Qian, Wenjing Zha, Lei Shi
Article Number: 93
Published online on: 04 February 2026

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Case Report Open Access

Comprehensive diagnosis and individualized treatment of multiple primary lung cancer: A case report

Guoxiong Zeng, Yunyan Zhou, Wang Wan, Biao Deng, Chunyuan Chen, Zhu Liang
Article Number: 92
Published online on: 03 February 2026

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Review Open Access

Pathophysiological mechanisms of fatigue and multidisciplinary management strategies (Review)

Hong Zhou, Wenwen Yu, Jiaming Lei, Runzhi Chang, Yingjia Cheng, Guorui Wang, Li Lin
Article Number: 91
Published online on: 03 February 2026

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Case Report Open Access

A rare upstream regulatory region mutation in APC presenting as classical familial adenomatous polyposis: A case report and literature review

Chi-Han Yang, Yen-Cheng Chen, Tsung-Kun Chang, Wei-Chih Su, Ching-Wen Huang, Hsiang-Lin Tsai, Jaw-Yuan Wang
Article Number: 90
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] lncRNA MIAT promote cell invasion and migration in esophageal cancer

Weiguo Zhang, Qiang Chen, Caipeng Lei
Article Number: 89
Published online on: 02 February 2026

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Review Open Access

Mitochondria‑driven ferroptosis in intervertebral disc degeneration: A novel target in age‑related spinal diseases (Review)

Yang Hou, Xiaolei Yang, Duorun Qiu, Lei Liu, Jiangang Shi, Yongfei Guo
Article Number: 88
Published online on: 02 February 2026

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Case Report

Preoperative treatment with thyroid artery embolization in a patient with a giant retrosternal goiter causing severe tracheal compression: A case report

Jingxian Li, Fang Wang, Yuanshu Du, Yonghui Wang
Article Number: 87
Published online on: 02 February 2026

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Case Report Open Access

Gastric wall thickening and gastric outlet obstruction due to peritoneal metastasis in breast cancer: A case report

Bin He, Lin Ling Li, Ting Yu, Yu Tan, Ling Zhang
Article Number: 86
Published online on: 29 January 2026

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Article Open Access

Myrrh ameliorates endometriosis by enhancing ER stress‑related apoptotic cell death

Bo-Sung Kim, Minkyoung Cho, Jung Ho Han, Jung-Sook Jin, Sung-Jin Bae, Yunju Jo, Dongryeol Ryu, Yerim Joo, Seon Beom Kim, Jongkil Joo, Inhye Kim, Ki-Tae Ha
Article Number: 85
Published online on: 29 January 2026

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