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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October-2016 Volume 14 Issue 4

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Notch signaling in cerebrovascular diseases (Review)

Zhiyou Cai, Bin Zhao, Yanqing Deng, Shouqin Shangguan, Faming Zhou, Wenqing Zhou, Xiaoli Li, Yanfeng Li, Guanghui Chen
Pages: 2883-2898
Published online on: 19 August 2016

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Review Open Access

Endocannabinoid system: Role in depression, reward and pain control (Review)

Wen‑Juan Huang, Wei‑Wei Chen, Xia Zhang
Pages: 2899-2903
Published online on: 01 August 2016

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Article Open Access

Silencing of TBX20 gene expression in rat myocardial and human embryonic kidney cells leads to cell cycle arrest in G2 phase

Peiyan Liu, Yueling Sun, Guangbin Qiu, Hongkun Jiang, Guangrong Qiu
Pages: 2904-2914
Published online on: 19 August 2016

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Article Open Access

A novel variant of androgen receptor is associated with idiopathic azoospermia

Lisha Mou, Yaoting Gui
Pages: 2915-2920
Published online on: 04 August 2016

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Article Open Access

Inhibitory effect of metformin combined with gemcitabine on pancreatic cancer cells in vitro and in vivo

Yuqi Shi, Zhilong He, Zhenyu Jia, Chunfang Xu
Pages: 2921-2928
Published online on: 04 August 2016

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Article Open Access

Sonic hedgehog protein regulates fibroblast growth factor 8 expression in metanephric explant culture from BALB/c mice: Possible mechanisms associated with renal morphogenesis

Xing Chen, Xiao‑Ming Hou, You‑Fei Fan, Yu‑Ting Jin, Yu‑Lin Wang
Pages: 2929-2936
Published online on: 09 August 2016

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Article Open Access

Anti-wrinkle effects of Sargassum muticum ethyl acetate fraction on ultraviolet B-irradiated hairless mouse skin and mechanistic evaluation in the human HaCaT keratinocyte cell line

Jae Hyoung Song, Mei Jing Piao, Xia Han, Kyoung Ah Kang, Hee Kyoung Kang, Weon Jong Yoon, Mi Hee Ko, Nam Ho Lee, Mi Young Lee, Sungwook Chae, Jin Won Hyun
Pages: 2937-2944
Published online on: 19 August 2016

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Article Open Access

Rspo2 suppresses CD36-mediated apoptosis in oxidized low density lipoprotein-induced macrophages

Hui Yan, Shuai Wang, Zhenwei Li, Zewei Sun, Jie Zan, Wenting Zhao, Yanyun Pan, Zhen Wang, Mingjie Wu, Jianhua Zhu
Pages: 2945-2952
Published online on: 19 August 2016

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Article Open Access

Lycopene inhibits the cell proliferation and invasion of human head and neck squamous cell carcinoma

Min Ye, Qundan Wu, Min Zhang, Jinbei Huang
Pages: 2953-2958
Published online on: 08 August 2016

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Article Open Access

Nicotinic α7 receptor inhibits the acylation stimulating protein‑induced production of monocyte chemoattractant protein‑1 and keratinocyte‑derived chemokine in adipocytes by modulating the p38 kinase and nuclear factor‑κB signaling pathways

Zhou‑Yang Jiao, Jing Wu, Chao Liu, Bing Wen, Wen‑Zeng Zhao, Xin‑Ling Du
Pages: 2959-2966
Published online on: 12 August 2016

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Article Open Access

A technical application of quantitative next generation sequencing for chimerism evaluation

Michelangelo Aloisio, Danilo Licastro, Luciana Caenazzo, Valentina Torboli, Angela D'Eustacchio, Giovanni Maria Severini, Emmanouil Athanasakis
Pages: 2967-2974
Published online on: 04 August 2016

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Article Open Access

miRNA-411 acts as a potential tumor suppressor miRNA via the downregulation of specificity protein 1 in breast cancer

Liangfeng Guo, Jianhui Yuan, Ni Xie, Huisheng Wu, Weicai Chen, Shufen Song, Xianming Wang
Pages: 2975-2982
Published online on: 19 August 2016

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Article Open Access

Toll‑like receptor 4 contributes to acute kidney injury after cardiopulmonary resuscitation in mice

Qingsong Zhang, Gang Li, Li Xu, Qian Li, Qianyan Wang, Yue Zhang, Qing Zhang, Peng Sun
Pages: 2983-2990
Published online on: 08 August 2016

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Article Open Access

Investigation of the association between miR‑181b, Bcl‑2 and LRIG1 in oral verrucous carcinoma

Zhi‑Yuan Deng, Yue‑Hong Wang, Hong‑Zhi Quan, Ou‑Sheng Liu, Yi‑Ping Li, Yuan Li, Wu Zhu, Krishna Munnee, Zhan‑Gui Tang
Pages: 2991-2996
Published online on: 09 August 2016

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Article Open Access

FSH aggravates bone loss in ovariectomised rats with experimental periapical periodontitis

Hua Qian, Xiaoyue Guan, Zhuan Bian
Pages: 2997-3006
Published online on: 09 August 2016

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Article Open Access

Quantum dot-based molecular imaging of cancer cell growth using a clone formation assay

Xia‑Fei Geng, Min Fang, Shao‑Ping Liu, Yan Li
Pages: 3007-3012
Published online on: 18 August 2016

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Article Open Access

Cabazitaxel-induced autophagy via the PI3K/Akt/mTOR pathway contributes to A549 cell death

Ruichao Huo, Lili Wang, Peijuan Liu, Yong Zhao, Caiqin Zhang, Bing Bai, Xueying Liu, Changhong Shi, Sanhua Wei, Hai Zhang
Pages: 3013-3020
Published online on: 19 August 2016

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Article Open Access

MicroRNA-588 suppresses tumor cell migration and invasion by targeting GRN in lung squamous cell carcinoma

Li Qian, Longlong Lin, Yufeng Du, Xiaoyan Hao, Yuze Zhao, Xuejun Liu
Pages: 3021-3028
Published online on: 19 August 2016

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Article Open Access

Dehydrocorydaline promotes myogenic differentiation via p38 MAPK activation

Miran Yoo, Sang‑Jin Lee, Yong Kee Kim, Dong‑Wan Seo, Nam‑In Baek, Jae‑Ha Ryu, Jong‑Sun Kang, Gyu‑Un Bae
Pages: 3029-3036
Published online on: 19 August 2016

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Article Open Access

Effect of autophagy induced by dexamethasone on senescence in chondrocytes

Enxing Xue, Yu Zhang, Bing Song, Jun Xiao, Zhanjun Shi
Pages: 3037-3044
Published online on: 22 August 2016

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Article Open Access

Human tonsil‑derived mesenchymal stromal cells enhanced myelopoiesis in a mouse model of allogeneic bone marrow transplantation

Jung‑Hwa Ryu, Minhwa Park, Bo‑Kyung Kim, Yu‑Hee Kim, So‑Youn Woo, Kyung‑Ha Ryu
Pages: 3045-3051
Published online on: 08 August 2016

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Article Open Access

Analysis of gene expression profile identifies potential biomarkers for atherosclerosis

Luran Liu, Yan Liu, Chang Liu, Zhuobo Zhang, Yaojun Du, Hao Zhao
Pages: 3052-3058
Published online on: 19 August 2016

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Article Open Access

Overexpression of gelsolin reduces the proliferation and invasion of colon carcinoma cells

Wen‑Xiang Li, Meng‑Xuan Yang, Xin‑Qiang Hong, Tian‑Geng Dong, Tuo Yi, Sheng‑Li Lin, Xin‑Yu Qin, Wei‑Xin Niu
Pages: 3059-3065
Published online on: 19 August 2016

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Article Open Access

Possible role of the Ec peptide of IGF‑1Ec in cartilage repair

Nikolaos Armakolas, Andreas Dimakakos, Athanasios Armakolas, Athanasios Antonopoulos, Michael Koutsilieris
Pages: 3066-3072
Published online on: 12 August 2016

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Article Open Access

Impact of quercetin‑induced changes in drug‑metabolizing enzyme and transporter expression on the pharmacokinetics of cyclosporine in rats

Yani Liu, Xiaomei Luo, Chunxiao Yang, Tingyu Yang, Jiali Zhou, Shaojun Shi
Pages: 3073-3085
Published online on: 09 August 2016

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Article Open Access

Allicin protects traumatic spinal cord injury through regulating the HSP70/Akt/iNOS pathway in mice

Shunyi Wang, Dongliang Ren
Pages: 3086-3092
Published online on: 19 August 2016

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Article Open Access

Solanum tuberosum L. cv Hongyoung extract inhibits 2,4‑dinitrochlorobenzene‑induced atopic dermatitis in NC/Nga mice

Myung Ah Kang, Se‑Young Choung
Pages: 3093-3103
Published online on: 08 August 2016

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Article Open Access

Mesenchymal stem cells in corneal neovascularization: Comparison of different application routes

Emma Ghazaryan, Yan Zhang, Yuxi He, Xin Liu, Ying Li, Jianan Xie, Guanfang Su
Pages: 3104-3112
Published online on: 11 August 2016

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Article Open Access

The study on mechanism of the modified Chinese herbal compound, jianpijiedu, on a mouse model of hepatic carcinoma cachexia

Baoguo Sun, Haoxuan Luo, Liuxiang Deng, Shijun Zhang, Zexiong Chen
Pages: 3113-3121
Published online on: 08 August 2016

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Article Open Access

Atorvastatin attenuates p‑cresyl sulfate‑induced atherogenesis and plaque instability in ApoE knockout mice

Hui Han, Yanjia Chen, Jinzhou Zhu, Jingwei Ni, Jiateng Sun, Ruiyan Zhang
Pages: 3122-3128
Published online on: 12 August 2016

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Article Open Access

A novel missense mutation of the GRK1 gene in Oguchi disease

Mehmet Yasin Teke, Mehmet Citirik, Serkan Kabacam, Suleyman Demircan, Mehmet Alikasifoglu
Pages: 3129-3133
Published online on: 09 August 2016

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Article Open Access

Reprogramming A375 cells to induced‑resembled neuronal cells by structured overexpression of specific transcription genes

Hengzhu Zhang, Min Wei, Yangyang Jiang, Xiaodong Wang, Lei She, Zhengcun Yan, Lun Dong, Lujun Pang, Xingdong Wang
Pages: 3134-3144
Published online on: 08 August 2016

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Article Open Access

KIF21A mutation in two Chinese families with congenital fibrosis of the extraocular muscles type 1 and 3

Jingchang Chen, Qingqing Ye, Daming Deng, Jianhua Yan, Houbian Lin, Tao Shen, Ying Lin
Pages: 3145-3151
Published online on: 11 August 2016

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Article Open Access

Hypolipidemic effects of HVC1 in a high cholesterol diet‑induced rat model of hyperlipidemia

Chae‑Yun Kim, Kyung‑Sook Chung, Se‑Yun Cheon, Kyungjin Lee, Inhye Ham, Ho‑Young Choi, Yong Baik Cho, Byoung‑Heon Cho, So Youn Mok, Hyo‑Jin An
Pages: 3152-3158
Published online on: 09 August 2016

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Article Open Access

Overexpression of CD44 is associated with the occurrence and migration of non-small cell lung cancer

Guanghu Li, Yufei Gao, Yongsheng Cui, Tao Zhang, Rui Cui, Yang Jiang, Jingwei Shi
Pages: 3159-3167
Published online on: 18 August 2016

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Article Open Access

Identification of distinct genes associated with seawater aspiration‑induced acute lung injury by gene expression profile analysis

Wei Liu, Lei Pan, Minlong Zhang, Liyan Bo, Congcong Li, Qingqing Liu, Li Wang, Faguang Jin
Pages: 3168-3178
Published online on: 09 August 2016

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Article Open Access

Natural compound oblongifolin C inhibits autophagic flux, and induces apoptosis and mitochondrial dysfunction in human cholangiocarcinoma QBC939 cells

Aiqing Zhang, Wei He, Huimin Shi, Xiaodan Huang, Guozhong Ji
Pages: 3179-3183
Published online on: 04 August 2016

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Article Open Access

Potential fluid biomarkers for pathological brain changes in Alzheimer's disease: Implication for the screening of cognitive frailty

Qingwei Ruan, Grazia D'Onofrio, Daniele Sancarlo, Antonio Greco, Zhuowei Yu
Pages: 3184-3198
Published online on: 09 August 2016

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Article Open Access

Paris saponin VII suppresses osteosarcoma cell migration and invasion by inhibiting MMP‑2/9 production via the p38 MAPK signaling pathway

Gong Cheng, Fengguang Gao, Xiujiang Sun, Haiyong Bi, Yonglin Zhu
Pages: 3199-3205
Published online on: 22 August 2016

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Article Open Access

Ameliorative effects of Artemisia argyi Folium extract on 2,4‑dinitrochlorobenzene‑induced atopic dermatitis‑like lesions in BALB/c mice

Hyoung‑Min Han, Seung‑Ju Kim, Jong‑Sik Kim, Bum Hoi Kim, Hai Woong Lee, Yong Tae Lee, Kyung‑Hwa Kang
Pages: 3206-3214
Published online on: 19 August 2016

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Article Open Access

Age‑dependent increase in the expression of antioxidant‑like protein‑1 in the gerbil hippocampus

Jin‑A Park, Joon Ha Park, Ji Hyeon Ahn, Jong‑Dai Kim, Moo‑Ho Won, Choong‑Hyun Lee
Pages: 3215-3219
Published online on: 09 August 2016

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Article Open Access

Epidermal growth factor receptor kinase substrate 8 promotes the metastasis of cervical cancer via the epithelial-mesenchymal transition

Qian Li, Wei Bao, Qiong Fan, Wen‑Jing Shi, Zhu‑Nan Li, Ying Xu, Dan Wu
Pages: 3220-3228
Published online on: 18 August 2016

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Article

Curcumin attenuates cyclosporine A‑induced renal fibrosis by inhibiting hypermethylation of the klotho promoter

Ying Hu, Lijun Mou, Fuye Yang, Haiyan Tu, Wanbing Lin
Pages: 3229-3236
Published online on: 08 August 2016

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Article

Dose response of dexmedetomidine‑induced resistance to hypoxia in mice

Wanying Pan, Xiaoxiao Hua, Yueting Wang, Ruixian Guo, Jingfu Chen, Liqiu Mo
Pages: 3237-3242
Published online on: 04 August 2016

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Article

Traditional Chinese medicine: Pivotal role of the spleen in the metabolism of aristolochic acid I in rats is dependent on oatp2a1

Ting Xiang, Zhangbin Yang, Baoguo Sun, Haoxuan Luo, Shijun Zhang, Bin Ren, Xiaoling Chen, Xin Zhou, Zexiong Chen
Pages: 3243-3250
Published online on: 09 August 2016

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Article

Molecular genetic analysis and phenotypic characteristics of a consanguineous family with glycogen storage disease type Ia

Yili Lu, Liyin Wang, Jun Li, Beibei Wu, Huiping Wu, Yue Luo, Zi‑Bing Jin, Xiaoou Shan
Pages: 3251-3254
Published online on: 09 August 2016

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Article

Fucoidan reduces oxidative stress by regulating the gene expression of HO‑1 and SOD‑1 through the Nrf2/ERK signaling pathway in HaCaT cells

Min Ju Ryu, Ha Sook Chung
Pages: 3255-3260
Published online on: 11 August 2016

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Article

HOXC6 promotes gastric cancer cell invasion by upregulating the expression of MMP9

Shi‑Wei Chen, Qing Zhang, Zhi‑Feng Xu, Hai‑Ping Wang, Yi Shi, Feng Xu, Wen‑Jian Zhang, Ping Wang, Yong Li
Pages: 3261-3268
Published online on: 19 August 2016

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Article

Characterization of multidrug‑resistant osteosarcoma sublines and the molecular mechanisms of resistance

Jian‑Zeng Yang, Shu‑Rong Ma, Xiao‑Li Rong, Mei‑Ju Zhu, Qiu‑Ye Ji, Ling‑Jie Meng, Yi‑Yao Gao, Yu‑Dan Yang, Yan Wang
Pages: 3269-3276
Published online on: 04 August 2016

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Article

Jatrorrhizine hydrochloride attenuates hyperlipidemia in a high-fat diet-induced obesity mouse model

Weiwei Yang, Liping She, Kun Yu, Shan Yan, Xuefeng Zhang, Xiaoyi Tian, Shuren Ma, Xiwen Zhang
Pages: 3277-3284
Published online on: 18 August 2016

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Article

Let‑7 miRNAs sensitize breast cancer stem cells to radiation‑induced repression through inhibition of the cyclin D1/Akt1/Wnt1 signaling pathway

Huifang Sun, Changmao Ding, Huiyu Zhang, Jianbo Gao
Pages: 3285-3292
Published online on: 19 August 2016

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Article

Angiopoietin-like protein 4 improves glucose tolerance and insulin resistance but induces liver steatosis in high-fat-diet mice

Yi Wang, Li‑Ming Liu, Li Wei, Wei‑Wei Ye, Xiang‑Ying Meng, Feng Chen, Qian Xiao, Jian‑Yang Chen, Yong Zhou
Pages: 3293-3300
Published online on: 18 August 2016

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Article

Sphingomyelin synthase 2 affects CD14‑associated induction of NF‑κB by lipopolysaccharides in acute lung injury in mice

Shidong Hu, Yi Ding, Jie Gong, Nianlong Yan
Pages: 3301-3306
Published online on: 09 August 2016

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Article

A novel TBX20 loss‑of‑function mutation contributes to adult‑onset dilated cardiomyopathy or congenital atrial septal defect

Yi‑Meng Zhou, Xiao‑Yong Dai, Ri‑Tai Huang, Song Xue, Ying‑Jia Xu, Xing‑Biao Qiu, Yi‑Qing Yang
Pages: 3307-3314
Published online on: 09 August 2016

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Article

Correlation between low tapasin expression and impaired CD8+ T‑cell function in patients with chronic hepatitis B

Yuyan Tang, Jieling Wang, Yi Zhang, Meng Zhuo, Linlin Song, Zhenghao Tang, Guoqing Zang, Xiaohua Chen, Yongsheng Yu
Pages: 3315-3322
Published online on: 09 August 2016

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Article

Inflammation has a role in urethane‑induced lung cancer in C57BL/6J mice

Cai Xu, Lingyu Zhou, Lei Lu, Ting Chen, Siyu Wei, Xiaojing Lin, Xuemei Lian
Pages: 3323-3328
Published online on: 19 August 2016

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Article

TRIF is a regulator of TLR2-induced foam cell formation

Bin Huang, Dae‑Weon Park, Suk‑Hwan Baek
Pages: 3329-3335
Published online on: 19 August 2016

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Article

Distribution of fibroblast growth factors and their roles in skin fibroblast cell migration

Yong Huan Song, Yu Ting Zhu, Jian Ding, Fei Ya Zhou, Ji Xin Xue, Jin Hee Jung, Zhi Jie Li, Wei Yang Gao
Pages: 3336-3342
Published online on: 19 August 2016

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Article

miR‑205 suppresses cell proliferation, invasion, and metastasis via regulation of the PTEN/AKT pathway in renal cell carcinoma

Huiqiang Wang, Bin Chen, Bo Duan, Jiaxin Zheng, Xinyi Wu
Pages: 3343-3349
Published online on: 04 August 2016

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Article

Identification of microRNA profiles associated with refractory primary biliary cirrhosis

Teppei Sakamoto, Asahiro Morishita, Takako Nomura, Joji Tani, Hisaaki Miyoshi, Hirohiro Yoneyama, Hisakazu Iwama, Takashi Himoto, Tsutomu Masaki
Pages: 3350-3356
Published online on: 09 August 2016

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Article

PRDM16 is associated with evasion of apoptosis by prostatic cancer cells according to RNA interference screening

Shaoxing Zhu, Yipeng Xu, Mei Song, Guiping Chen, Hua Wang, Yang Zhao, Zongping Wang, Fangyin Li
Pages: 3357-3361
Published online on: 08 August 2016

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Article

Distal hereditary motor neuropathy type 7B with Dynactin 1 mutation

Sun Hee Hwang, Eun Ja Kim, Young Bin Hong, Jaesoon Joo, Sung Min Kim, Soo Hyun Nam, Hyun Dae Hong, Seung Hyun Kim, Kiwook Oh, Jeong‑Geun Lim, Jeong Hee Cho, Ki Wha Chung, Byung‑Ok Choi
Pages: 3362-3368
Published online on: 22 August 2016

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Article

S1PR1 mediates anti‑apoptotic/pro‑proliferative processes in human acute myeloid leukemia cells

Xiao‑Qian Xu, Chong‑Mei Huang, Yi‑Fan Zhang, Li Chen, Hui Cheng, Jian‑Min Wang
Pages: 3369-3375
Published online on: 12 August 2016

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Article

The protective role of p72 in doxorubicin‑induced cardiomyocytes injury in vitro

Bin Lin, Feng Wang, Jiaxiang Wang, Chengyang Xu, Hui Zhao, Zhaoyun Cheng, Deguang Feng
Pages: 3376-3380
Published online on: 08 August 2016

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Article

Inhibitory effects of Shenkang injection and its main component emodin on the proliferation of high glucose‑induced renal mesangial cells through cell cycle regulation and induction of apoptosis

Shouzhu Xu, Yanying Lv, Jing Zhao, Junping Wang, Xing Zhao, Siwang Wang
Pages: 3381-3388
Published online on: 12 August 2016

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Article

Lycorine protects cartilage through suppressing the expression of matrix metalloprotenases in rat chondrocytes and in a mouse osteoarthritis model

Shuai Chen, Xiang‑Qian Fang, Jian‑Feng Zhang, Yan Ma, Xiao‑Zhen Tang, Zhi‑Jie Zhou, Ji‑Ying Wang, An Qin, Shun‑Wu Fan
Pages: 3389-3396
Published online on: 08 August 2016

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Article

Renoprotective effects of ursolic acid on ischemia/reperfusion‑induced acute kidney injury through oxidative stress, inflammation and the inhibition of STAT3 and NF‑κB activities

Jun Peng, Xingfeng Ren, Tianbiao Lan, Yan Chen, Ziyun Shao, Cheng Yang
Pages: 3397-3402
Published online on: 19 August 2016

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Article

Neuroprotective effects of caffeic acid phenethyl ester against sevoflurane‑induced neuronal degeneration in the hippocampus of neonatal rats involve MAPK and PI3K/Akt signaling pathways

Li‑Yan Wang, Zhi‑Jun Tang, Yu‑Zeng Han
Pages: 3403-3412
Published online on: 04 August 2016

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Article

Dexmedetomidine pretreatment attenuates propofol‑induced neurotoxicity in neuronal cultures from the rat hippocampus

Yi Wei, Junhua Hu, Yubing Liang, Yuling Zhong, Dan He, Yi Qin, Li Li, Jing Chen, Qiang Xiao, Yubo Xie
Pages: 3413-3420
Published online on: 12 August 2016

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Article

miR‑483‑5p promotes growth, invasion and self‑renewal of gastric cancer stem cells by Wnt/β‑catenin signaling

Kai Wu, Longan Ma, Jinxiang Zhu
Pages: 3421-3428
Published online on: 08 August 2016

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Article

Collagen regulates transforming growth factor-β receptors of HL-1 cardiomyocytes through activation of stretch and integrin signaling

Yen‑Yu Lu, Yung‑Kuo Lin, Yu‑Hsun Kao, Cheng‑Chih Chung, Yung‑Hsin Yeh, Shih‑Ann Chen, Yi‑Jen Chen
Pages: 3429-3436
Published online on: 18 August 2016

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Article

Knockdown of TACC3 inhibits trophoblast cell migration and invasion through the PI3K/Akt signaling pathway

Xiaojun Zhu, Qianqian Cao, Xia Li, Zhengping Wang
Pages: 3437-3442
Published online on: 19 August 2016

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Article

Genetic variants in FGFR2 and TNRC9 genes are associated with breast cancer risk in Pakistani women

Ayesha Mazhar, Farrukh Jamil, Qamar Bashir, Munawar Saleem Ahmad, Misbah Masood, Imrana Tanvir, Naeem Rashid, Abdul Waheed, Muhammad Naveed Afzal, Muhammad Akram Tariq
Pages: 3443-3451
Published online on: 18 August 2016

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Article

Exosomes derived from human mesenchymal stem cells promote gastric cancer cell growth and migration via the activation of the Akt pathway

Hongbing Gu, Runbi Ji, Xu Zhang, Mei Wang, Wei Zhu, Hui Qian, Yongchang Chen, Pengcheng Jiang, Wenrong Xu
Pages: 3452-3458
Published online on: 11 August 2016

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Article

Plasma heme oxygenase-1 is decreased in peripheral artery disease patients

Salvatore Santo Signorelli, Guido Li Volsi, Valerio Fiore, Marco Mangiafico, Ignazio Barbagallo, Rosalba Parenti, Manfredi Rizzo, Giovanni Li Volti
Pages: 3459-3463
Published online on: 19 August 2016

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Article

Inhibitory effects of B‑cell translocation gene 2 on skin cancer cells via the Wnt/β‑catenin signaling pathway

Shou‑Song Gao, Xiao‑Hong Yang, Meng Wang
Pages: 3464-3468
Published online on: 08 August 2016

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Article

Decitabine enhances bortezomib treatment in RPMI 8226 multiple myeloma cells

Yang Cao, Guo‑Qiang Qiu, Hao‑Qing Wu, Zhi‑Lin Wang, Yan Lin, Wei Wu, Xiao‑Bao Xie, Wei‑Ying Gu
Pages: 3469-3475
Published online on: 19 August 2016

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Article

Endogenously synthesized n-3 fatty acids in fat-1 transgenic mice prevent melanoma progression by increasing E-cadherin expression and inhibiting β-catenin signaling

Xuan Yin, Xiong‑Wei Yu, Pan Zhu, Yuan‑Ming Zhang, Xiao‑Hong Zhang, Feng Wang, Jin‑Jie Zhang, Wang Yan, Yang Xi, Jian‑Bo Wan, Jing‑Xuan Kang, Zu‑Quan Zou, Shi‑Zhong Bu
Pages: 3476-3484
Published online on: 18 August 2016

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Article

Expression of early and late cellular damage markers by ARPE-19 cells following prolonged treatment with UV-A radiation

Giuseppe Tringali, Beatrice Sampaolese, Maria Elisabetta Clementi
Pages: 3485-3489
Published online on: 19 August 2016

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Article

C‑reactive protein/oxidized low density lipoprotein/β2‑glycoprotein i complexes induce lipid accumulation and inflammatory reaction in macrophages via p38/mitogen‑activated protein kinase and nuclear factor‑κB signaling pathways

Jie Wang, Mei‑Jun Feng, Rui Zhang, De‑Min Yu, Sai‑Jun Zhou, Rui Chen, Pei Yu
Pages: 3490-3498
Published online on: 11 August 2016

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Article Open Access

Differential activation of c‑Fos in the paraventricular nuclei of the hypothalamus and thalamus following myocardial infarction in rats

Hyun‑Jin Tae, Seung Min Park, Jeong Hwi Cho, In Hye Kim, Ji Hyeon Ahn, Joon Ha Park, Moo‑Ho Won, Bai Hui Chen, Bich‑Na Shin, Myoung Cheol Shin, Choong Hyun Lee, Seongkweon Hong, Jae‑Chul Lee, Jun Hwi Cho
Pages: 3503-3508
Published online on: 07 September 2016

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Article Open Access

Histone deacetylase enzyme silencing using shRNAs enhances radiosensitivity of SW579 thyroid cancer cells

Ye Wang, Tao Jin, Xueming Dai, Dongwang Yan, Zhihai Peng
Pages: 3509-3516
Published online on: 05 September 2016

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Notch 2 signaling contributes to cell growth, anti-apoptosis and metastasis in laryngeal squamous cell carcinoma

You Zou, Fang Fang, Yong‑Jun Ding, Meng‑Yuan Dai, Xing Yi, Chen Chen, Ze‑Zhang Tao, Shi‑Ming Chen
Pages: 3517-3524
Published online on: 29 August 2016

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Severity of pancreatitis‑associated intestinal mucosal barrier injury is reduced following treatment with the NADPH oxidase inhibitor apocynin

Wenhong Deng, Ablikim Abliz, Sheng Xu, Rongze Sun, Wenyi Guo, Qiao Shi, Jia Yu, Weixing Wang
Pages: 3525-3534
Published online on: 26 August 2016

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Apoptosis repressor with caspase recruitment domain enhances survival and promotes osteogenic differentiation of human osteoblast cells under Zoledronate treatment

Longwei Hu, Jing Han, Xi Yang, Yang Wang, Hongya Pan, Liqun Xu
Pages: 3535-3542
Published online on: 24 August 2016

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Article Open Access

ZFAT gene variant association with multiple sclerosis in the Arabian Gulf population: A genetic basis for gender-associated susceptibility

Sonia Bourguiba‑Hachemi, Tebah K. Ashkanani, Fatema J. Kadhem, Wassim Y. Almawi, Raed Alroughani, M. Dahmani Fathallah
Pages: 3543-3550
Published online on: 30 August 2016

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Frequently rearranged in advanced T‑cell lymphomas‑1 demonstrates oncogenic properties in prostate cancer

Wei Zhang, Hua Xiong, Yanmei Zou, Sanpeng Xu, Lanping Quan, Xianglin Yuan, Ningzhi Xu, Yihua Wang
Pages: 3551-3558
Published online on: 05 September 2016

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Tormentic acid inhibits H2O2-induced oxidative stress and inflammation in rat vascular smooth muscle cells via inhibition of the NF-κB signaling pathway

Yu‑Lun Wang, Gen‑Yi Sun, Ying Zhang, Jia‑Jun He, Shen Zheng, Jing‑Na Lin
Pages: 3559-3564
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The differentiation potential of gingival mesenchymal stem cells induced by apical tooth germ cell‑conditioned medium

Yan Chen, Hongwei Liu
Pages: 3565-3572
Published online on: 06 September 2016

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Pro‑neurogenic effects of andrographolide on RSC96 Schwann cells in vitro Corrigendum in /10.3892/mmr.2020.11278

Fuben Xu, Huayu Wu, Kun Zhang, Peizhen Lv, Li Zheng, Jinmin Zhao
Pages: 3573-3580
Published online on: 06 September 2016

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Protective effect of active perfusion in porcine models of acute myocardial ischemia

Zanxiang Feng, Zhifu Mao, Shengjun Dong, Baohui Liu
Pages: 3581-3587
Published online on: 24 August 2016

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Curcumin ameliorates high‑fat diet‑induced spermatogenesis dysfunction

Yang Mu, Wen‑Jie Yan, Tai‑Lang Yin, Jing Yang
Pages: 3588-3594
Published online on: 05 September 2016

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Article Open Access

Impact of siRNA targeting of β-catenin on differentiation of rat neural stem cells and gene expression of Ngn1 and BMP4 following in vitro hypoxic-ischemic brain damage

Xiaoying Zhang, Cuicui Zhu, Qiong Luo, Jv Dong, Lv Liu, Min Li, Hongtao Zhu, Xiangping Ma, Jun Wang
Pages: 3595-3601
Published online on: 24 August 2016

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Upregulation of retinoic acid receptor-β reverses drug resistance in cholangiocarcinoma cells by enhancing susceptibility to apoptosis

Hong‑Yue Ren, Bo Chen, Gui‑Li Huang, Yu Liu, Dong‑Yan Shen
Pages: 3602-3608
Published online on: 02 September 2016

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Development of a model based on biochemical, real‑time tissue elastography and ultrasound data for the staging of liver fibrosis and cirrhosis in patients with chronic hepatitis B

Shi‑Hao Xu, Qiao Li, Yuan‑Ping Hu, Li Ying
Pages: 3609-3619
Published online on: 26 August 2016

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Curcumin inhibits osteoclastogenic potential in PBMCs from rheumatoid arthritis patients via the suppression of MAPK/RANK/c-Fos/NFATc1 signaling pathways

Wei Shang, Ling‑Jie Zhao, Xiao‑Lei Dong, Zhi‑Ming Zhao, Jing Li, Bei‑Bei Zhang, Hui Cai
Pages: 3620-3626
Published online on: 25 August 2016

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Activated leukocyte cell adhesion molecule regulates the interaction between pancreatic cancer cells and stellate cells

Wei‑Wei Zhang, Shu‑Hui Zhan, Chang‑Xin Geng, Xin Sun, Mert Erkan, Jörg Kleeff, Xiang‑Jun Xie
Pages: 3627-3633
Published online on: 26 August 2016

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In vitro antitumor activity of the ethyl acetate extract of Potentilla chinensis in osteosarcoma cancer cells Retraction in /10.3892/mmr.2021.12129

Guang Wan, Jin‑Gang Tao, Guo‑Dong Wang, Shen‑Peng Liu, Hong‑Xing Zhao, Qiu‑Dong Liang
Pages: 3634-3640
Published online on: 26 August 2016

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Case Report Open Access

A novel KMT2D mutation resulting in Kabuki syndrome: A case report

Jun Lu, Guiling Mo, Yaojun Ling, Lijuan Ji
Pages: 3641-3645
Published online on: 26 August 2016

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Resveratrol pretreatment attenuates injury and promotes proliferation of neural stem cells following oxygen-glucose deprivation/reoxygenation by upregulating the expression of Nrf2, HO-1 and NQO1 in vitro

Changbo Shen, Wei Cheng, Pingping Yu, Li Wang, Lulin Zhou, Li Zeng, Qin Yang
Pages: 3646-3654
Published online on: 24 August 2016

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Article Open Access

Cytoplasmic translocation of high-mobility group box-1 protein is induced by diabetes and high glucose in retinal pericytes

Junghyun Kim, Chan‑Sik Kim, Eunjin Sohn, Jin Sook Kim
Pages: 3655-3661
Published online on: 02 September 2016

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Liraglutide attenuates the osteoblastic differentiation of MC3T3‑E1 cells by modulating AMPK/mTOR signaling

Xiong‑Ke Hu, Xin‑Hua Yin, Hong‑Qi Zhang, Chao‑Feng Guo, Ming‑Xing Tang
Pages: 3662-3668
Published online on: 06 September 2016

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Fibronectin expression is critical for liver fibrogenesis in vivo and in vitro

Xiao‑Ya Liu, Rui‑Xia Liu, Fei Hou, Li‑Jian Cui, Chun-Yun Li, Cheng Chi, Entong Yi, Yan Wen, Cheng‑Hong Yin
Pages: 3669-3675
Published online on: 25 August 2016

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Expressing human SHOX in Shox2SHOX KI/KI mice leads to congenital osteoarthritis‑like disease of the temporomandibular joint in postnatal mice

Wenna Liang, Xihai Li, Houhuang Chen, Xiang Shao, Xuejuan Lin, Jianying Shen, Shanshan Ding, Jie Kang, Candong Li
Pages: 3676-3682
Published online on: 05 September 2016

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Resveratrol attenuates acute kidney injury by inhibiting death receptor‑mediated apoptotic pathways in a cisplatin‑induced rat model

Qiufa Hao, Xiaoyan Xiao, Junhui Zhen, Jinbo Feng, Chun Song, Bei Jiang, Zhao Hu
Pages: 3683-3689
Published online on: 05 September 2016

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Hydroxysafflor yellow A exerts antioxidant effects in a rat model of traumatic brain injury

Yang Wang, Chunhu Zhang, Weijun Peng, Zian Xia, Pingping Gan, Wei Huang, Yafei Shi, Rong Fan
Pages: 3690-3696
Published online on: 06 September 2016

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Expression of claudins, occludin, junction adhesion molecule A and zona occludens 1 in canine organs

Changhwan Ahn, Da‑Hye Shin, Dongoh Lee, Su‑Myung Kang, Ju‑Hyung Seok, Hee Young Kang, Eui‑Bae Jeung
Pages: 3697-3703
Published online on: 06 September 2016

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Antiviral activities of atractylon from Atractylodis Rhizoma

Yang Cheng, Jing‑Yin Mai, Tian‑Lu Hou, Jian Ping, Jian‑Jie Chen
Pages: 3704-3710
Published online on: 05 September 2016

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Article

Beneficial effects of grape seed proanthocyanidin extract on arterial remodeling in spontaneously hypertensive rats via protecting against oxidative stress

Ying Liang, Jian Wang, Haiqing Gao, Quanzhen Wang, Jun Zhang, Jie Qiu
Pages: 3711-3718
Published online on: 01 September 2016

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Article

Effects of sphingosylphosphorylcholine on cryopreserved fat tissue graft survival

Yong Chan Bae, Chi Won Choi, Kyeong Wook Nam, Ji Sun Song, Jae Woo Lee
Pages: 3719-3724
Published online on: 26 August 2016

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Article

shRNA‑mediated silencing of TARBP2 inhibits NCI‑H1299 non‑small cell lung cancer cell invasion and migration via the JNK/STAT3/AKT pathway

Yue Shi, Duo Zuo, Xia Wang, Meng Han, Yan Wu
Pages: 3725-3730
Published online on: 06 September 2016

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Article

Clinical features and genetic diagnosis of hereditary spinocerebellar ataxia 3

Yaoguang Wang, Xiaokai Yang, Weide Ma, Jinxin Li, Qingyuan Zhang, Shuqi Xia, Hai Wang, Chenghui Zhang, Xiaomin Xu, Jiayong Zheng
Pages: 3731-3734
Published online on: 05 September 2016

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Article

Haptoglobin protein and mRNA expression in psoriasis and its clinical significance

Fu-Jun Tian, Ying-Ying Zhang, Li-Qian Liu, Ying Xiong, Zong-Shan Wang, Shou-Zhong Wang
Pages: 3735-3742
Published online on: 25 August 2016

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Article

Heparin inhibits the inflammation and proliferation of human rheumatoid arthritis fibroblast‑like synoviocytes through the NF‑κB pathway

Li Qi, Xiaoli Zhang, Xiaofei Wang
Pages: 3743-3748
Published online on: 06 September 2016

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Article

Anti‑inflammatory effects of Ciwujianoside C3, extracted from the leaves of Acanthopanax henryi (Oliv.) Harms, on LPS‑stimulated RAW 264.7 cells

Da‑Hye Kang, Ok‑Hwa Kang, Zhi Li, Su‑Hyun Mun, Yun‑Soo Seo, Ryong Kong, Zhou Tian, Xiangqian Liu, Dong‑Yeul Kwon
Pages: 3749-3758
Published online on: 05 September 2016

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Article

Expression of far upstream element binding protein 1 in B‑cell non‑Hodgkin lymphoma is correlated with tumor growth and cell‑adhesion mediated drug resistance

Yuejiao Huang, Xiaohong Xu, Lili Ji, Yuchan Wang, Shitao Wang, Jie Tang, Xianting Huang, Xiaojing Yang, Yunhua He, Song He, Chun Cheng
Pages: 3759-3768
Published online on: 06 September 2016

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Article

Osteoprotective effects of osthole in a mouse model of 5/6 nephrectomy through inhibiting osteoclast formation

Xiaofeng Li, Chunchun Xue, Libo Wang, Dezhi Tang, Jian Huang, Yongjian Zhao, Yan Chen, Dongfeng Zhao, Qi Shi, Yongjun Wang, Bing Shu
Pages: 3769-3776
Published online on: 29 August 2016

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Antioxidant effects of Cirsium setidens extract on oxidative stress in human mesenchymal stem cells

Jun Hee Lee, Ho Kyung Jung, Yong‑Seok Han, Yeo Min Yoon, Chul Won Yun, Hwa Yeon Sun, Hyun Woo Cho, Sang Hun Lee
Pages: 3777-3784
Published online on: 05 September 2016

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Article

Bioinformatics analysis of gene expression profiles of dermatomyositis

Liang‑Yuan Chen, Zhao‑Lei Cui, Fan‑Cui Hua, Weng‑Jing Yang, Ye Bai, Feng‑Hua Lan
Pages: 3785-3790
Published online on: 02 September 2016

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Article

Low mutation percentage of KRAS and BRAF genes in Brazilian anal tumors

Lucas Tadeu Bidinotto, Carlos A R Véo, Edgar Aleman Loaiza, Alessandra Paulino Santos De França, Adriana Tarla Lorenzi, Luciana Albina Reis Rosa, Cristina Mendes De Oliveira, José Eduardo Levi, Cristovam Scapulatempo‑Neto, Adhemar Longatto‑Filho, Rui Manuel Reis
Pages: 3791-3797
Published online on: 26 August 2016

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Article

Glucocorticoid treatment inhibits intracerebral hemorrhage‑induced inflammation by targeting the microRNA‑155/SOCS‑1 signaling pathway

Hong‑Fei Xu, Xiao‑Yun Fang, Shao‑Hua Zhu, Xue‑Hua Xu, Zhi‑Xiang Zhang, Zu‑Feng Wang, Zi‑Qin Zhao, Yu‑Jie Ding, Lu‑Yang Tao
Pages: 3798-3804
Published online on: 06 September 2016

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Article

Possible tumor suppressive role of the miR-144/451 cluster in esophageal carcinoma as determined by principal component regression analysis

Zhikui Gao, Ran Liu, Juan Liao, Miao Yang, Enchun Pan, Lihong Yin, Yuepu Pu
Pages: 3805-3813
Published online on: 30 August 2016

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Article

Proteomic analysis of selective cytotoxic anticancer properties of flavonoids isolated from Citrus platymamma on A549 human lung cancer cells

Arulkumar Nagappan, Venu Venkatarame Gowda Saralamma, Gyeong Eun Hong, Ho Jeong Lee, Sung Chul Shin, Eun Hee Kim, Won Sup Lee, Gon Sup Kim
Pages: 3814-3822
Published online on: 24 August 2016

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Article

Identification of differentially expressed genes affecting hair and cashmere growth in the Laiwu black goat by microarray

Jinshan Zhao, Hegang Li, Kaidong Liu, Baoxun Zhang, Peipei Li, Jianning He, Ming Cheng, Wei De, Jifeng Liu, Yaofeng Zhao, Lihua Yang, Nan Liu
Pages: 3823-3831
Published online on: 06 September 2016

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Article

Effects of tongxinluo on angiogenesis in the carotid adventitia of hyperlipidemic rabbits

Jianhua Zhou, Bingfeng Cao, Weiping Ju, Sen Liu, Jianguang Song, Lixia Liu
Pages: 3832-3840
Published online on: 25 August 2016

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Article

Matrine induces the hepatic differentiation of WB-F344 rat hepatic progenitor cells and inhibits Jagged 1/HES1 signaling

Zhiyun Yang, Li Wang, Xianbo Wang
Pages: 3841-3847
Published online on: 24 August 2016

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Article

Nkx2.5/CARP signaling pathway contributes to the regulation of ion channel remodeling induced by rapid pacing in rat atrial myocytes

Wei Wang, Yun Zhu, Jianguang Yi, Wei Cheng
Pages: 3848-3854
Published online on: 06 September 2016

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Article

p53, Bcl-2 and cox-2 are involved in berberine hydrochloride-induced apoptosis of HeLa229 cells

Hai‑Yan Wang, Hai‑Zhong Yu, Sheng‑Mou Huang, Yu‑Lan Zheng
Pages: 3855-3861
Published online on: 31 August 2016

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Article

Comparison of bone marrow tissue- and adipose tissue-derived mesenchymal stem cells in the treatment of sepsis in a murine model of lipopolysaccharide-induced sepsis

Hao Ou, Shangping Zhao, Yue Peng, Xuefei Xiao, Qianlu Wang, Huaizeng Liu, Xianzhong Xiao, Mingshi Yang
Pages: 3862-3870
Published online on: 30 August 2016

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Article

Effects of hydrogen sulfide on the expression of alkaline phosphatase, osteocalcin and collagen type I in human periodontal ligament cells induced by tension force stimulation

Jing Qin, Yongmei Hua
Pages: 3871-3877
Published online on: 26 August 2016

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Article

S100B suppresses the differentiation of C3H/10T1/2 murine embryonic mesenchymal cells into osteoblasts

Dong Li, Kaihua Li, Gang Chen, Jianlong Xia, Ting Yang, Ping Cai, Chen Yao, Yongjiang Yang, Shichang Yan, Rihua Zhang, Hui Chen
Pages: 3878-3886
Published online on: 01 September 2016

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Article

Co‑culture of fibroblast‑like synoviocytes with umbilical cord‑mesenchymal stem cells inhibits expression of pro‑inflammatory proteins, induces apoptosis and promotes chondrogenesis

Jingqi Zeng, Fan Wang, Minzhi Mao
Pages: 3887-3893
Published online on: 06 September 2016

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Article

Effect of high-fat diet-induced obesity on the Akt/FoxO/Smad signaling pathway and the follicular development of the mouse ovary

Yanqing Wu, Zhenghong Zhang, Xinghui Liao, Lingbin Qi, Yiping Liu, Zhengchao Wang
Pages: 3894-3900
Published online on: 25 August 2016

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Article

Mild hypothermia protects against early brain injury in rats following subarachnoid hemorrhage via the TrkB/ERK/CREB signaling pathway

Ou Lv, Fenggang Zhou, Yongri Zheng, Qingsong Li, Jianjiao Wang, Yulan Zhu
Pages: 3901-3907
Published online on: 05 September 2016

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Article

Regulation of the pacemaker activities in cultured interstitial cells of Cajal by Citrus unshiu peel extracts

Ji Hwan Shim, Soo Jin Lee, Huijin Gim, Hyun Jung Kim, Taewon Han, Jae Goo Kim, Eun Yeong Lim, Yun Tai Kim, Byung Joo Kim
Pages: 3908-3916
Published online on: 30 August 2016

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Article

Inhibiting the role of Skp2 suppresses cell proliferation and tumorigenesis of human gastric cancer cells via the upregulation of p27kip1

Yanguang Wen, Kuansong Wang, Kaiyan Yang
Pages: 3917-3924
Published online on: 25 August 2016

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Article

Activation of mTOR signaling leads to orthopedic surgery-induced cognitive decline in mice through β-amyloid accumulation and tau phosphorylation

Wenzhen Shen, Keliang Lu, Jiawan Wang, Anshi Wu, Yun Yue
Pages: 3925-3934
Published online on: 01 September 2016

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Article

Myeloid-derived suppressor cells are elevated in patients with psoriasis and produce various molecules

Dan Ilkovitch, Laura K. Ferris
Pages: 3935-3940
Published online on: 26 August 2016

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Article

Iodine regulates G2/M progression induced by CCL21/CCR7 interaction in primary cultures of papillary thyroid cancer cells with RET/PTC expression

You‑Yuan Zhang, Ze‑Bing Liu, Xuan‑Guang Ye, Wei‑Min Ren
Pages: 3941-3946
Published online on: 29 August 2016

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Article

Structure and antioxidant activity of a novel polysaccharide derived from Amanita caesarea

Yuanxiu Zhu, Xiang Ding, Mei Wang, Yiling Hou, Wanru Hou, Changwu Yue
Pages: 3947-3954
Published online on: 30 August 2016

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Article

SH003 selectively induces p73‑dependent apoptosis in triple‑negative breast cancer cells

Eun Kyoung Choi, Seung‑Mi Kim, Seung‑Woo Hong, Jai‑Hee Moon, Jae‑Sik Shin, Jeong Hee Kim, Ih‑Yeon Hwang, Soo‑A Jung, Dae‑Hee Lee, Eun Young Lee, Seul Lee, Hyunwoo Kim, Daejin Kim, Yeong Seok Kim, Youn Kyung Choi, Hyo In Kim, Hyeong Sim Choi, Sung‑Gook Cho, Jeong Eun Kim, Kyu Pyo Kim, Yong Sang Hong, Won Keun Lee, Jung Shin Lee, Tae Won Kim, Seong‑Gyu Ko, Dong‑Hoon Jin
Pages: 3955-3960
Published online on: 06 September 2016

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Article

Sp1 downregulates proinflammatory cytokine‑induced catabolic gene expression in nucleus pulposus cells

Kang Xu, Xiaofei Wang, Qianshi Zhang, Anjing Liang, Haipeng Zhu, Dongsheng Huang, Chunhai Li, Wei Ye
Pages: 3961-3968
Published online on: 06 September 2016

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Article

Influence of the availability of iron during hypoxia on the genes associated with apoptotic activity and local iron metabolism in rat H9C2 cardiomyocytes and L6G8C5 skeletal myocytes

Magdalena Dziegala, Monika Kasztura, Kamil Kobak, Jacek Bania, Waldemar Banasiak, Piotr Ponikowski, Ewa A. Jankowska
Pages: 3969-3977
Published online on: 05 September 2016

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Article

Role of histone modification in 12‑lipoxygenase‑associated p21 gene regulation

Yingchun Cui, Nian Liu, Fuzhe Ma, Weixia Sun, Hao Wu, Zhonggao Xu, Hang Yuan
Pages: 3978-3984
Published online on: 06 September 2016

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Article

Berberine induces pacemaker potential inhibition via cGMP-dependent ATP-sensitive K+ channels by stimulating mu/delta opioid receptors in cultured interstitial cells of Cajal from mouse small intestine

Hyun Jung Kim, Hyungwoo Kim, Myeong Ho Jung, Young Kyu Kwon, Byung Joo Kim
Pages: 3985-3991
Published online on: 01 September 2016

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Article

Effects of endomorphin-1 postconditioning on myocardial ischemia/reperfusion injury and myocardial cell apoptosis in a rat model

Wei‑Ping Zhang, Qiao‑Feng Zong, Qin Gao, Ying Yu, Xiao‑Yu Gu, Ya Wang, Zheng‑Hong Li, Min Ge
Pages: 3992-3998
Published online on: 31 August 2016

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Article

Inhibiting autophagy promotes endoplasmic reticulum stress and the ROS‑induced nod‑like receptor 3‑dependent proinflammatory response in HepG2 cells

Jia‑Jing Yin, Guangying Xie, Ning Zhang, Yanbo Li
Pages: 3999-4007
Published online on: 05 September 2016

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Retraction Open Access

[Retracted] Production of interleukin‑4 in CD133+ cervical cancer stem cells promotes resistance to apoptosis and initiates tumor growth

Chun‑Tao Liu, Ying Xin, Chun‑Yan Tong, Bing Li, Hong‑Li Bao, Cai‑Yun Zhang, Xue‑Hui Wang
Pages: 4008-4008
Published online on: 07 September 2016

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May-2026 Volume 33 Issue 5

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Identification of STMN1 as a lactylation‑related driver of lung cancer progression using Mendelian randomization

Yifan Cai, Yucheng Zhong, Honglin Wang, Shuang Zhu, Fang Huang, Qiuyue Zhang, Shaobo Hu
Article Number: 156
Published online on: 30 March 2026

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Advances in the mechanisms of extracellular vesicles and circulating tumor cells in hepatocellular carcinoma metastasis (Review)

Sitong Yi, Wenxin Liu, Zhaohui Wang
Article Number: 155
Published online on: 30 March 2026

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Diagnostic importance of serum markers in lung cancer

Qichen Liang, Jianmei Song, Haixiang Wei, Lu Ning, Baoyu He, Ziteng Zhang
Article Number: 154
Published online on: 30 March 2026

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VSNL1 attenuates hypoxia‑induced myocardial apoptosis by regulating the CNP/NPRB pathway

Xing Yang, Wenjuan Fang, Rui Chang, Linlin Ma, Xiaoyan Chen, Yanfei Li
Article Number: 153
Published online on: 30 March 2026

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Stabilin‑1: An immunoregulatory scavenger receptor in inflammation and tissue homeostasis (Review)

Xiao-Lei Xiang, Xin-Tong Ye, Yu-Tong Wu, Chen Chen, Chu-Ying Yu, Su-Ting Qian, Dan-Li Cai
Article Number: 152
Published online on: 26 March 2026

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Mechanism and therapeutic prospects of adipose tissue B lymphocytes in obesity and obesity‑associated metabolic diseases (Review)

Hong Wang, Hongyuan Lv, Xiaolin Zhang, Meifang Liu, Liyuan Wang
Article Number: 151
Published online on: 26 March 2026

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Tonsil‑derived mesenchymal stem cell‑derived extracellular vesicles suppress MAPK‑NF‑κB signaling and restore osteogenic differentiation in LPS‑stimulated periodontal ligament fibroblasts

Won-Jung Bae, Su Kang Kim, Han-Soo Kim, Sang Wook Kang, Ju Yeon Ban
Article Number: 150
Published online on: 26 March 2026

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Succinylation modification in diabetes and diabetic complications: Mechanisms and functions (Review)

Yeteng Xiong, Fei Luo, Bingnan Li, Qinfeng Yang
Article Number: 149
Published online on: 26 March 2026

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Polyphyllin II regulates ROS levels and promotes ferroptosis in bladder cancer cells

Quanlai Qiao, Ruifang Guo, Zhonghua Sun, Yaxin Shi, Yuning Xie, Zhiyong Liu
Article Number: 148
Published online on: 26 March 2026

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Veronicastrum sibiricum (L.) Pennell extract alleviates inflammation‑induced muscle atrophy through NLRP3 inflammasome regulation and mitochondrial function restoration

Eunhye Lee, Minjeong Kwon, Ju-Ock Nam
Article Number: 147
Published online on: 26 March 2026

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Role and clinical importance of lactylation in tumors (Review)

Chaowei Zhang, Xinyu Tang, Yuxuan Han, Weiyi Yao, Qing Hong, Yanan Zhu, Na Chen
Article Number: 146
Published online on: 26 March 2026

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Photodynamic therapy: A paradigm shift in overcoming drug‑resistant tuberculosis (Review)

Shuhao Cheng, Yuqing Wang, Jie Yao, Guodong Cheng, Gengzhi Ye, Fapeng Shi, Xiaolei Ma
Article Number: 145
Published online on: 26 March 2026

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Heterogeneous nuclear ribonucleoprotein K in cancer biology and its therapeutic applications (Review)

Yiyu Qin, Yang Zhou
Article Number: 144
Published online on: 26 March 2026

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Retraction Open Access

[Retracted] Na+/K+‑ATPase DR region‑specific antibody protects U251 cells against hypoxia reperfusion‑induced injury via the PI3K/AKT and ERK pathways

Huilin Gong, Pengbiao Lü, Jiangwei Zhang, Dandong Li, Jin Zheng, Jinning Song
Article Number: 143
Published online on: 23 March 2026

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Multi‑omics and their integration in psoriasis research (Review)

Hengyan Zhang, Danping Li, Lijuan Zhu, Heguo Yan, Licong Yang, Xuesong Yang, Ye Zhou
Article Number: 142
Published online on: 23 March 2026

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LDHA protects vascular endothelial cells from oxidative stress‑induced mitochondrial damage via HIF‑1α activation and glycolytic reprogramming

Beibei Dai, Lili Yang, Yu Zhang, Aiyong Yu
Article Number: 141
Published online on: 23 March 2026

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Mechanism of BRCC36 affecting cardiac rupture after acute infarction through the Wnt‑JNK signaling pathway

Yongzhe Guo, Linyan Chen, Shumei Li, Xintao Zhang, Huizhong Lin
Article Number: 140
Published online on: 20 March 2026

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Correction Open Access

[Corrigendum] Puerarin alleviates the ototoxicity of gentamicin by inhibiting the mitochondria‑dependent apoptosis pathway

Ping Niu, Yuxuan Sun, Shiyi Wang, Guang Li, Xiaomin Tang, Jiaqiang Sun, Chunchen Pan, Jingwu Sun
Article Number: 139
Published online on: 19 March 2026

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Role of liver X receptors in the pathogenesis and treatment of chronic liver disease (Review)

Honghui You, Xiangjun Tang, Xiaoyan Fu, Jiaqi Zhou, Liyuan Wang, Hongxia Zhang, Xianhong Du, Shujuan Liang, Meifang Liu
Article Number: 138
Published online on: 19 March 2026

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Mechanistic insights and therapeutic potential of sphingosine‑1‑phosphate in the development of pulmonary fibrosis (Review)

Yanling Qin, Chenqi Tang, Sen Tan, Guangnan Liu
Article Number: 137
Published online on: 18 March 2026

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Advances in the biological functions of miR‑205 in various diseases (Review)

Dandan Chai, Hua Du, Yingxu Shi
Article Number: 136
Published online on: 18 March 2026

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Retraction Open Access

[Retracted] MicroRNA‑25‑3p regulates human nucleus pulposus cell proliferation and apoptosis in intervertebral disc degeneration by targeting Bim

Zhifang Zhao, Jie Zheng, Youchen Ye, Kefeng Zhao, Ruozhang Wang, Ran Wang
Article Number: 135
Published online on: 16 March 2026

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Precision medicine approach to coronary artery disease: Haptoglobin phenotype‑guided risk assessment

Zhengxin He, Hong Liu, Keran Jia, Daxin Lei, Liyun An, Jia Wang, Fukun Wang
Article Number: 134
Published online on: 12 March 2026

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Expression of Concern Open Access

[Expression of Concern] Dexmedetomidine protects against sepsis‑associated encephalopathy through Hsp90/AKT signaling

Lijun Yin, Xuejun Chen, Hongbo Ji, Shunli Gao
Article Number: 133
Published online on: 11 March 2026

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Glucose‑driven TRIB3 enhances the tumorigenic potential of colon cancer via the PI3K/AKT pathway

Yunting Bai, Xuying Huang, Guangyu An, Yang Ge, Rui Yan, Dan Yu
Article Number: 132
Published online on: 10 March 2026

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Retraction Open Access

[Retracted] miR‑222 regulates brain injury and inflammation following intracerebral hemorrhage by targeting ITGB8

Yan-Yan Bai, Jun-Zhi Niu
Article Number: 131
Published online on: 09 March 2026

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Dexmedetomidine protects against myocardial ischemia reperfusion injury by inhibiting the TLR2‑NF‑κB pathway in diabetic mice

Zhengjie Chen, Liangyu Zheng, Gang Chen
Article Number: 130
Published online on: 06 March 2026

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Long non‑coding RNA NKILA regulates the JAK2/STAT3 pathway to exacerbate TGF‑β1‑mediated renal fibrosis

Yu Han, Siqi Yang, Jing Zhang, Yaoguang Wang, Xi Zhao, Huan Liu
Article Number: 129
Published online on: 05 March 2026

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Retraction Open Access

[Retracted] Combination of HSP90 and autophagy inhibitors promotes hepatocellular carcinoma apoptosis following incomplete thermal ablation

Fen Chen, Haiyang Xie, Haiwei Bao, Laurencia Violetta, Shusen Zheng
Article Number: 128
Published online on: 05 March 2026

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Review Open Access

Advances regarding physiological functions and mechanisms of theaflavin‑3,3'‑digallate (Review)

Teng Ma, Siwei Zhang, Miaomiao Xiao, Zhijian Ma, Junhong Guan
Article Number: 127
Published online on: 04 March 2026

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Mechanisms and therapeutic potential of glycyrrhizic acid: Insights into key signaling pathways and disease modulation (Review)

Jinjin Yu, Huiheng Qu, Weicheng Xu, Yiming Fang, Nan Wang, Wei Shi
Article Number: 126
Published online on: 04 March 2026

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Pyroptosis in cerebral ischemia‑reperfusion injury: Molecular mechanisms and therapeutic implications (Review)

Ze Li, Qiuli Ming, Tianyu Yang, Mengna Liu, Linpeng Fu, Jingshuang Yang, Zhaofeng Lu
Article Number: 125
Published online on: 04 March 2026

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Characteristics of chromosomal instability‑related lncRNAs associated with progression and prognosis in breast cancer

Qi Chen, Hui Chen, Hui Yang, Yin Tao, Xiaolan Zhu
Article Number: 124
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Associations between Huwe1 and autophagy in rat cerebral neuron oxygen‑glucose deprivation and reperfusion injury 

Guo-Qian He, Yan Chen, Hui-Juan Liao, Wen-Ming Xu, Wei Zhang, Guo-Lin He
Article Number: 123
Published online on: 26 February 2026

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June-2026 Volume 33 Issue 6

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Mechanism of and research progress on alterations in the RET gene in thyroid cancer (Review)

Meng Wei, Rui Wang, Jincan Qian, Qiang Fang, Jun Tao
Article Number: 164
Published online on: 02 April 2026

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Current research progress on extracellular vesicles derived from mesenchymal stem cells in tuberculosis treatment (Review)

Dejun Fan, Yan Yang, Li Yang
Article Number: 163
Published online on: 01 April 2026

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Uremic toxin p‑cresyl sulfate enhances the calcification of aortic valvular interstitial cells via klotho/sirtuin‑1 signaling

Shao-Jung Li, Tzu-Yu Cheng, Yu-Hsun Kao, Wei-Yu Chen, Cheng-Chih Chung, Nguyen Ngoc Trang, Pao-Huan Chen, Yi-Jen Chen
Article Number: 162
Published online on: 01 April 2026

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Exercise‑induced extracellular vesicle microRNA regulates physiological function (Review)

Zhonglei Wang, Wenjue Guo, Haojia He, Yi Zhang, Na Li
Article Number: 161
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis

Ruiqiao Guan, Zhihao Li, Xiaohong Dai, Wei Zou, Xueping Yu, Hao Liu, Qiuxin Chen, Wei Teng, Peng Liu, Xiaoying Liu, Shanshan Dong
Article Number: 160
Published online on: 01 April 2026

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Emerging roles of POLR2L of RNA polymerase II dynamics and disease mechanisms (Review)

Beomwoo Lee, Changgyu Son, Sunho Eom, Yuwen Li, Seon-Hwan Kim, Jongsun Park
Article Number: 159
Published online on: 30 March 2026

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Combining bioinformatics prediction with experimental validation to explore the ameliorative effect of Psoralea corylifolia on vitiligo

Chen Zhang, Zhanhong Cao, Mengyang Wei, Xuanxuan Zhu, Yan Yan, Zhenhua Wang, Meng Zhang
Article Number: 158
Published online on: 30 March 2026

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Retraction Open Access

[Retracted] All‑trans‑retinoic acid inhibits chondrogenesis of rat embryo hindlimb bud mesenchymal cells by down­regulating p53 expression

Tao-Gen Zhang, Xue-Dong Li, Guo-Yong Yu, Peng Xie, Yun-Guo Wang, Zhao-Yong Liu, Quan Hong, De-Zhong Liu, Shi-Xin Du
Article Number: 157
Published online on: 30 March 2026

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