Journal Articles

Review

Mycobacteriophages: An important tool for the diagnosis of Mycobacterium tuberculosis (Review)

Xiaoyan Fu, Mingxing Ding, Ning Zhang, Jicheng Li

Pages: 13-19 Published online on: 05 March 2015
Article Open Access

Conditioned medium from umbilical cord mesenchymal stem cells induces migration and angiogenesis

Chongyang Shen, Puchang Lie, Tianyu Miao, Meixing Yu, Qiao Lu, Ting Feng, Jinrong Li, Tingting Zu, Xiaohuan Liu, Hong Li

Pages: 20-30 Published online on: 04 March 2015
Article Open Access

Osteogenic cell fractions isolated from mouse tongue muscle

Koji Harada, Toyoko Harada, Tarannum Ferdous, Takanori Takenawa, Yoshiya Ueyama

Pages: 31-36 Published online on: 13 February 2015
Article Open Access

N-acetylcysteine treatment following spinal cord trauma reduces neural tissue damage and improves locomotor function in mice

Jian Guo, Yiqiao Li, Zhong Chen, Zhennian He, Bin Zhang, Yonghuan Li, Jianghua Hu, Mingyuan Han, Yuanlin Xu, Yongfu Li

Pages: 37-44 Published online on: 26 February 2015
Article Open Access

Klotho gene delivery ameliorates renal hypertrophy and fibrosis in streptozotocin-induced diabetic rats by suppressing the Rho-associated coiled-coil kinase signaling pathway

Minghong Deng, Yumei Luo, Yunkui Li, Qiuchen Yang, Xiaoqin Deng, Ping Wu, Houxun Ma

Pages: 45-54 Published online on: 17 February 2015
Article Open Access

Screening for characteristic microRNAs between pre-invasive and invasive stages of cervical cancer

Xiao‑Lu Zhu, Shang‑Yun Wen, Zhi‑Hong Ai, Juan Wang, Yan‑Li Xu, Yin‑Cheng Teng

Pages: 55-62 Published online on: 17 February 2015
Article Open Access
Article Open Access

Afzelin attenuates asthma phenotypes by downregulation of GATA3 in a murine model of asthma

Wenbo Zhou, Xiuhong Nie

Pages: 71-76 Published online on: 26 February 2015
Article Open Access

Expression of integrin-binding protein Nischarin in metastatic breast cancer

Jie Chen, Wei‑Liang Feng, Wen‑Ju Mo, Xiao‑Wen Ding, Shang‑Nao Xie

Pages: 77-82 Published online on: 18 February 2015
Article Open Access

Overexpression of adenosine deaminase acting on RNA 1 in chordoma tissues is associated with chordoma pathogenesis by reducing miR‑125a and miR‑10a expression

Lei Kuang, Guohua Lv, Bing Wang, Lei Li, Yuliang Dai, Yawei Li

Pages: 93-98 Published online on: 12 February 2015
Article Open Access

Ischemic postconditioning inhibits apoptosis in an in vitro proximal tubular cell model

Xiaodong Weng, Lei Wang, Hui Chen, Xiuheng Liu, Tao Qiu, Zhiyuan Chen

Pages: 99-104 Published online on: 12 February 2015
Article Open Access

Circulating microRNA-196a as a candidate diagnostic biomarker for chronic hepatitis C

Bo Liu, Ying Xiang, Heng‑Shu Zhang

Pages: 105-110 Published online on: 24 February 2015
Article Open Access

Cluster of differentiation 147 is a key molecule during hepatocellular carcinoma cell‑hepatic stellate cell cross‑talk in the rat liver

Tianyou Ma, Zhilun Wang, Zhantian Yang, Jinghong Chen

Pages: 111-118 Published online on: 04 March 2015
Article Open Access

Estrogen receptor α mediates the effects of notoginsenoside R1 on endotoxin-induced inflammatory and apoptotic responses in H9c2 cardiomyocytes

Lei Zhong, Xing‑Lu Zhou, Yan‑Song Liu, Yi‑Min Wang, Fei Ma, Bao‑Liang Guo, Zhao‑Qi Yan, Qing‑Yuan Zhang

Pages: 119-126 Published online on: 27 February 2015
Article Open Access

Thymosin β4 promotes hepatoblastoma metastasis via the induction of epithelial-mesenchymal transition

Xiaojun Fu, Peiyuan Cui, Fangfang Chen, Jianzhong Xu, Li  Gong, Lei Jiang, Dakun Zhang, Yongtao Xiao

Pages: 127-132 Published online on: 16 February 2015
Article Open Access

Chitosan oligosaccharides in combination with Agaricus blazei Murill extract reduces hepatoma formation in mice with severe combined immunodeficiency

Ming‑Yang Yeh, Hung‑Sheng Shang, Hsu‑Feng Lu, Jason Chou, Chun Yeh, Jin‑Biou Chang, Hsiao‑Fang Hung, Wan‑Lin Kuo, Lung‑Yuan Wu, Jing‑Gung Chung

Pages: 133-140 Published online on: 09 March 2015
Article Open Access

Correlation between the expression of DNMT1, and GSTP1 and APC, and the methylation status of GSTP1 and APC in association with their clinical significance in prostate cancer

Weijie Zhang, Hongliang Jiao, Xudong Zhang, Ruihua Zhao, Feng Wang, Wei He, Hong Zong, Qingxia Fan, Liuxing Wang

Pages: 141-146 Published online on: 03 March 2015
Article Open Access

Fully human HER2/cluster of differentiation 3 bispecific antibody triggers potent and specific cytotoxicity of T lymphocytes against breast cancer

Yan Zhou, Lan‑Tu Gou, Zhi‑Hui Guo, Hai‑Rong Liu, Jiang‑Man Wang, Shu‑Xian Zhou, Jin‑Liang Yang, Xiao‑An Li

Pages: 147-154 Published online on: 05 March 2015
Case Report Open Access

A patient with unusual features and a 69.5 Mb duplication from a de novo extra der (9): A case report

Yu‑Chun Zhou, Cui Zhang, Jin‑Sheng Zhai, Tian‑Fu Li, Qiu‑Yue Wu, Wei‑Wei Li, Na Li, Xiao‑Jun Li, Yu-Feng Huang, Ying‑Xia Cui, Xin‑Yi Xia

Pages: 155-158 Published online on: 05 March 2015
Article Open Access

Protein identification from dried nipple aspirate fluid on Guthrie cards using mass spectrometry

Lucas Delmonico, Vivian Rabello Areias, Rodrigo César Pinto, Cintia Da Silva Matos, Marco Felipe Franco Rosa, Carolina Maria De Azevedo, Gilda Alves

Pages: 159-164 Published online on: 05 March 2015
Article Open Access

All-trans retinoic acid impairs the vasculogenic mimicry formation ability of U87 stem-like cells through promoting differentiation

Geng‑Qiang Ling, Yi‑Jing Liu, Yi‑Quan Ke, Lei Chen, Xiao‑Dan Jiang, Chuan‑Lu Jiang, Wei Ye

Pages: 165-172 Published online on: 06 March 2015
Article Open Access
Article Open Access

α-lipoic acid protects against hypoxia/reoxygenation-induced injury in human umbilical vein endothelial cells through suppression of apoptosis and autophagy

Jingjing Zhang, Houliang Deng, Li Liu, Xiaoxia Liu, Xialin Zuo, Qian Xu, Zhuomin Wu, Xiaobin Peng, Aimin Ji

Pages: 180-186 Published online on: 13 February 2015
Article Open Access

Impact of tissue type and content of neoplastic cells of samples on the quality of epidermal growth factor receptor mutation analysis among patients with lung adenocarcinoma

Panagiotis Paliogiannis, Federico Attene, Antonio Cossu, Efisio Defraia, Giuseppe Porcu, Annamaria Carta, Maria Ignazia Sotgiu, Antonio Pazzola, Lorenzo Cordero, Francesca Capelli, Giovanni Maria Fadda, Salvatore Ortu, Giovanni Sotgiu, Grazia Palomba, Maria Cristina Sini, Giuseppe Palmieri, Maria Colombino

Pages: 187-191 Published online on: 12 February 2015
Article Open Access

All‑trans‑retinoic acid inhibits chondrogenesis of rat embryo hindlimb bud mesenchymal cells by downregulating p53 expression

Tao‑Gen Zhang, Xue‑Dong Li, Guo‑Yong Yu, Peng Xie, Yun‑Guo Wang, Zhao‑Yong Liu, Quan Hong, De‑Zhong Liu, Shi‑Xin Du

Pages: 210-218 Published online on: 04 March 2015
Article Open Access

Monocyte chemotactic protein-1 promotes the proliferation and invasion of osteosarcoma cells and upregulates the expression of AKT

Quanchi Chen, Wei Sun, Yuxin Liao, Hui Zeng, Liancheng Shan, Fei Yin, Zhuoying Wang, Zifei Zhou, Yingqi Hua, Zhengdong Cai

Pages: 219-225 Published online on: 18 February 2015
Article Open Access

Repression of metadherin inhibits biological behavior of prostate cancer cells and enhances their sensitivity to cisplatin

Yong‑Bao Wei, Qiong Guo, Yun‑Liang Gao, Bin Yan, Zhao Wang, Jin‑Rui Yang, Wei Liu

Pages: 226-232 Published online on: 16 February 2015
Article

Interleukin-4 affects the mature phenotype and function of rat bone marrow-derived dendritic cells

Shizhong Wang, Xiao Sun, Haijun Zhou, Zhichao Zhu, Wenjie Zhao, Chunfu Zhu

Pages: 233-237 Published online on: 13 February 2015
Article

A subset of circulating microRNAs is expressed differently in patients with myocardial infarction

Jianqiu Liang, Shuchang Bai, Liang Su, Chen Li, Jiandi Wu, Zhangqing Xia, Dingli Xu

Pages: 243-247 Published online on: 04 March 2015
Article

Estrogen receptorβ2 regulates interlukin-12 receptorβ2 expression via p38 mitogen-activated protein kinase signaling and inhibits non-small-cell lung cancer proliferation and invasion

Zhao‑Guo Liu, Xing‑Yuan Jiao, Zhen‑Guang Chen, Ke Feng, Hong‑He Luo

Pages: 248-254 Published online on: 17 February 2015
Article

Arg972 insulin receptor substrate‑1 enhances tumor necrosis factor‑α‑induced apoptosis in osteoblasts

Yunhui You, Shiqing Liu, Lijuan Peng, Mei Long, Hongxiang Deng, Hongjun Zhao

Pages: 255-260 Published online on: 09 March 2015
Article

Basic fibroblast growth factor lentiviral vector-transfected sheep bone marrow mesenchymal stem cells and non-specific osteogenic gene expression

Yang Hu, Qin Zhang, Lei Zhang, Xiao‑Xue Tang, Hui‑Yu He

Pages: 267-272 Published online on: 27 February 2015
Article

Inhibitory effects of autologous γ-irradiated cell conditioned medium on osteoblasts in vitro

Xu‑Fang Li, Guo‑Ying Zhu, Jian‑Ping Wang, Yu Wang

Pages: 273-280 Published online on: 16 February 2015
Article

Optimized codon usage enhances the expression and immunogenicity of DNA vaccine encoding Taenia solium oncosphere TSOL18 gene

Yuan‑Yuan Wang, Xue‑Lian Chang, Zhi‑Yong Tao, Xiao‑Li Wang, Yu‑Meng Jiao, Yong Chen, Wen‑Juan Qi, Hui Xia, Xiao‑Di Yang, Xin Sun, Ji‑Long Shen, Qiang Fang

Pages: 281-288 Published online on: 24 February 2015
Article

Ubiquitin‑modified hepatitis B virus core antigen effectively facilitates antigen presentation and enhances cytotoxic T lymphocyte activity via the cytoplasmic transduction peptide in vitro

Linlin Song, Meng Zhuo, Yuyan Tang, Xiaohua Chen, Yongsheng Yu, Zhenghao Tang, Guoqing Zang

Pages: 289-296 Published online on: 13 February 2015
Article

Synergistic hepatotoxicity by cadmium and chlorpyrifos: Disordered hepatic lipid homeostasis

Wei He, Wenli Guo, Yi Qian, Shuping Zhang, Difeng Ren, Sijin Liu

Pages: 303-308 Published online on: 24 February 2015
Article

Pirfenidone inhibits proliferation, arrests the cell cycle, and downregulates heat shock protein‑47 and collagen type I in rat hepatic stellate cells in vitro

Xian‑Hong Xiang, Tian‑Peng Jiang, Shuai Zhang, Jie Song, Xing Li, Jian‑Yong Yang, Shi Zhou

Pages: 309-314 Published online on: 03 March 2015
Article

Protective mechanism of Korean Red Ginseng in cisplatin-induced ototoxicity through attenuation of nuclear factor-κB and caspase-1 activation

Su‑Jin Kim, Hyun Jeong Kwak, Dae‑Seung Kim, Hyun‑Myung Choi, Jung‑Eun Sim, Sung‑Hoon Kim, Jae‑Young Um, Seung‑Heon Hong

Pages: 315-322 Published online on: 27 February 2015
Article

Plasma sphingolipids: Potential biomarkers for severe hepatic fibrosis in chronic hepatitis C

Jun‑Feng Li, Feng Qu, Su‑Jun Zheng, Feng Ren, Hui‑Li Wu, Mei Liu, Jin‑Yu Ren, Yu Chen, Zhong‑Ping Duan, Jin‑Lan Zhang

Pages: 323-330 Published online on: 17 February 2015
Article

High-dose insulin inhibits gap junction intercellular communication in vascular smooth muscle cells

Ou Bian, Haishan Zhang, Qigang Guan, Yingxian Sun, Dingyin Zeng

Pages: 331-336 Published online on: 05 March 2015
Article

Apogossypolone induces reactive oxygen species accumulation and controls cell cycle progression in Raji Burkkit's lymphoma cells

Zhe‑Yu Hu, Fei Xu, Rui Sun, Yan‑Feng Chen, Dong‑Sheng Zhang, Yu‑Hua Fan, Jian Sun

Pages: 337-344 Published online on: 03 March 2015
Article

Estimation of the environmental effect of natural volatile organic compounds from Chamaecyparis obtusa and their effect on atopic dermatitis-like skin lesions in mice

Hyun Yang, Changhwan Ahn, In‑Gyu Choi, Won‑Sil Choi, Mi‑Jin Park, Sung‑Suk Lee, Don‑Ha Choi, Eui‑Bae Jeung

Pages: 345-350 Published online on: 05 March 2015
Article

Bioinformatics analysis of abnormal DNA methylation in muscle samples from monozygotic twins discordant for type 2 diabetes

Fei Liu, Qianqian Sun, Lingxiao Wang, Shuangshuang Nie, Jun Li

Pages: 351-356 Published online on: 06 March 2015
Article

αB-crystallin reduces ristocetin‑induced soluble CD40 ligand release in human platelets: Suppression of thromboxane A2 generation

Masanori Tsujimoto, Tomoaki Doi, Gen Kuroyanagi, Naohiro Yamamoto, Rie Matsushima‑Nishiwaki, Yuko Iida, Yukiko Enomoto, Hiroki Iida, Shinji Ogura, Takanobu Otsuka, Haruhiko Tokuda, Osamu Kozawa, Toru Iwama

Pages: 357-362 Published online on: 06 March 2015
Article

Short hairpin RNA targeting AKT1 and PI3K/p85 suppresses the proliferation and self-renewal of lung cancer stem cells

Ai‑Gui Jiang, Hui‑Yu Lu, De‑Geng Zhang, Li‑Xin Zhang, Xiao‑Yan Gao

Pages: 363-370 Published online on: 26 February 2015
Article

Effect of astragaloside IV against rat myocardial cell apoptosis induced by oxidative stress via mitochondrial ATP-sensitive potassium channels

Feng‑Ying Guan, Shi‑Jie Yang, Jinxiang Liu, Si‑Rui Yang

Pages: 371-376 Published online on: 27 February 2015
Article

Lentivirus-mediated knockdown of rhomboid domain containing 1 inhibits colorectal cancer cell growth

Junyi Han, Junchao Bai, Yao Yang, Hua Yin, Wei Gao, Aiguo Lu, Fei Liu, Haiyan Ge, Zhongmin Liu, Jinyi Wang, Lan Zhong

Pages: 377-381 Published online on: 17 February 2015
Article

Icariin recovers the osteogenic differentiation and bone formation of bone marrow stromal cells from a rat model of estrogen deficiency-induced osteoporosis

Zhiqiang Luo, Minglu Liu, Likun Sun, Feilong Rui

Pages: 382-388 Published online on: 17 February 2015
Article

Activation of the unfolded protein response in aged human lenses

He‑Zhen Tang, Li‑Min Yang

Pages: 389-393 Published online on: 04 March 2015
Article

Ribonucleotide reductase M2 subunit expression and prognostic value in nasopharyngeal carcinoma

Ping Han, Zhi-Rui Lin, Li-Hua Xu, Qian Zhong, Xiao-Fen Zhu, Fa-Ya Liang, Qian Cai, Xiao-Ming Huang, Mu-Sheng Zeng

Pages: 401-409 Published online on: 16 February 2015
Article

Prenatal nicotine exposure induces gender-associated left ventricular-arterial uncoupling in adult offspring

Zhenhua Wang, Qiufang Ouyang, Ziyang Huang, Ling Lin, Er'mei Yu, Markus W. Ferrari

Pages: 410-418 Published online on: 17 February 2015
Article

Identification of a mutation in the WISP3 gene in three unrelated families with progressive pseudorheumatoid dysplasia

Yafen Yu, Man Hu, Xuesha Xing, Fang Li, Ying Song, Yang Luo, Hongwei Ma

Pages: 419-425 Published online on: 04 March 2015
Article

Metastasis‑associated in colon cancer‑1 is associated with poor prognosis in hepatocellular carcinoma, partly by promoting proliferation through enhanced glucose metabolism

Yaoqing Li, Zhongtang Lu, Zheyong Liang, Dong Ji, Pengfei Zhang, Qingguang Liu, Xin Zheng, Yingmin Yao

Pages: 426-434 Published online on: 04 March 2015
Article

Synergistic combination of histone deacetylase inhibitor suberoylanilide hydroxamic acid and oncolytic adenovirus ZD55-TRAIL as a therapy against cervical cancer

Xiujun Han, Shibing Wang, Wenjing Zhou, Ying Li, Wen Lei, Weiguo Lv

Pages: 435-441 Published online on: 16 February 2015
Article

Downregulation of the expression of B‑cell lymphoma‑extra large by RNA interference induces apoptosis and enhances the radiosensitivity of non‑small cell lung cancer cells

Changbin Yang, Wei Huang, Ling Yan, Yu Wang, Weili Wang, Dezhi Liu, Xiaojun Zuo

Pages: 449-455 Published online on: 12 February 2015
Article

Synergistic effects of combined treatment with simvastatin and exemestane on MCF‑7 human breast cancer cells

Yuanyuan Shen, Yingying Du, Ying Zhang, Yueyin Pan

Pages: 456-462 Published online on: 03 March 2015
Article

MicroRNA-21, induced by high glucose, modulates macrophage apoptosis via programmed cell death 4

Yuan‑Yuan Shang, Ning‑Ning Fang, Feng Wang, Hui Wang, Zhi‑Hao Wang, Meng‑Xiong Tang, Jie Peng, Yun Zhang, Wei Zhang, Ming Zhong

Pages: 463-469 Published online on: 27 February 2015
Article
Article

Overexpression of serine/threonine‑protein kinase-1 in pancreatic cancer tissue: Serine/threonine-protein kinase-1 knockdown increases the chemosensitivity of pancreatic cancer cells

Qingguang Wang, Dong Xu, Chao Han, Min Tu, Qing Du, Jingjing Zhang, Yi Zhu, Lijian Xu

Pages: 475-481 Published online on: 05 March 2015
Article

Identification and function analysis of contrary genes in Dupuytren's contracture

Xianglu Ji, Feng Tian, Lijie Tian

Pages: 482-488 Published online on: 09 March 2015
Article

Association of genetic polymorphisms in the telomerase reverse transcriptase gene with prostate cancer aggressiveness

Dapeng Wu, Hongjie Yu, Jielin Sun, Jun Qi, Qiang Liu, Ruipeng Li, Siqun Lily Zheng, Jianfeng Xu, Jian Kang

Pages: 489-497 Published online on: 04 March 2015
Article

Inhibition of the JAK2/STAT3 signaling pathway exerts a therapeutic effect on osteosarcoma

Jun Yan, Qianliang Wang, Kang Zou, Li Wang, Eric B. Schwartz, James R. Fuchs, Zugen Zheng, Jianqiang Wu

Pages: 498-502 Published online on: 05 March 2015
Article

Trophoblast glycoprotein promotes pancreatic ductal adenocarcinoma cell metastasis through Wnt/planar cell polarity signaling

Ping He, Shuheng Jiang, Mingze Ma, Yang Wang, Rongkun Li, Fang Fang, Guangang Tian, Zhigang Zhang

Pages: 503-509 Published online on: 04 March 2015
Case Report

A novel endoglin mutation in hereditary hemorrhagic telangiectasia type 1: A case report

Yanjun Lu, Yaowu Zhu, Lili Shi, Hongtao Zhen, Ziyong Sun, Liming Cheng

Pages: 510-512 Published online on: 05 March 2015
Article

Effects of RNA interference-mediated NRP-1 silencing on the proliferation and apoptosis of breast cancer cells

Zhengxiang Han, Guan Jiang, Yingying Zhang, Jie Xu, Chong Chen, Lansheng Zhang, Zhenyuan Xu, Xiuping Du

Pages: 513-519 Published online on: 03 March 2015
Article

Metformin alleviates high glucose‑mediated oxidative stress in rat glomerular mesangial cells by modulation of p38 mitogen-activated protein kinase expression in vitro

Xin‑Ming Yao, Shan‑Dong Ye, Chun‑Chun Xiao, Jun‑Fei Gu, Di Yang, Shan Wang

Pages: 520-526 Published online on: 06 March 2015
Article

Deregulated microRNA species in the plasma and placenta of patients with preeclampsia

Sheng Yang, Hailing Li, Qinyu Ge, Li Guo, Feng Chen

Pages: 527-534 Published online on: 04 March 2015
Article

Inhibition of autophagy by 3-methyladenine potentiates sulforaphane-induced cell death of BE(2)-C human neuroblastoma cells

Irena Horwacik, Monika Gaik, Małgorzata Durbas, Elżbieta Boratyn, Grzegorz Zając, Katarzyna Szychowska, Małgorzata Szczodrak, Henryk Kołoczek, Hanna Rokita

Pages: 535-542 Published online on: 18 February 2015
Article

Serum pentraxin 3 is a novel marker in Crohn's disease

Jingbo Chen, Xiaolin Xu, Lijian Xia, Xiangpeng Xi, Bo Liu, Mingyu Yang

Pages: 543-546 Published online on: 06 March 2015
Article

Inhibition of livin expression suppresses cell proliferation and enhances chemosensitivity to cisplatin in human lung adenocarcinoma cells

Li Zhuang, Li‑Da Shen, Kun Li, Run‑Xiang Yang, Qin‑Yong Zhang, Yun Chen, Chun‑Lin Gao, Chao Dong, Qing Bi, Jing‑Nan Tao, Xiao‑Nan Wang, Qing Tian

Pages: 547-552 Published online on: 18 February 2015
Article

B-cell lymphoma 2 and β-catenin expression in colorectal cancer and their prognostic role following surgery

Manuela Balzi, Maria Novella Ringressi, Paola Faraoni, Catherine Booth, Antonio Taddei, Luca Boni, Paolo Bechi

Pages: 553-560 Published online on: 24 February 2015
Article

MicroRNA-125b is involved in atherosclerosis obliterans in vitro by targeting podocalyxin

Xiaobing Li, Na Yao, Juan Zhang, Zhenjiang Liu

Pages: 561-568 Published online on: 24 February 2015
Article

Inhibitory effect of receptor for advanced glycation end product‑specific small interfering RNAs on the development of hepatic fibrosis in primary rat hepatic stellate cells

Jin‑Rong Xia, Ting‑Ting Chen, Wei‑Dong Li, Feng‑Lin Lu, Juan Liu, Xiao‑Gang Cai, Qin Lu, Cui-Ping Yang

Pages: 569-574 Published online on: 12 February 2015
Article

FoxO6 inhibits cell proliferation in lung carcinoma through up-regulation of USP7

Hong-Jun Hu, Li-Guo Zhang, Zhen-Hua Wang, Xi-Xi Guo

Pages: 575-580 Published online on: 17 February 2015
Article

Ku70 is essential for histone deacetylase inhibitor trichostatin A-induced apoptosis

Jin Meng, Feng Zhang, Xu‑Tao Zhang, Tao Zhang, Yu‑Hua Li, Lei Fan, Yang Sun, He‑Long Zhang, Qi‑Bing Mei

Pages: 581-586 Published online on: 16 February 2015
Article

Nodal activates smad and extracellular signal-regulated kinases 1/2 pathways promoting renal cell carcinoma proliferation

Zhiwei Zhang, Tao Jiang, Quanlin Li, Jianbo Wang, Deyong Yang, Xiancheng Li, Qifei Wang, Xishuang Song

Pages: 587-594 Published online on: 12 February 2015
Article

Interleukin-1β induced nuclear factor-κB binds to a disintegrin-like and metalloproteinase with thrombospondin type 1 motif 9 promoter in human chondrosarcoma cells

Aynur Altuntas, Sevil Oskay Halacli, Ozlem Cakmak, Gonul Erden, Sumeyya Akyol, Veli Ugurcu, Satoshi Hirohata, Kadir Demircan

Pages: 595-600 Published online on: 06 March 2015
Article

Simultaneous silencing of XIAP and survivin causes partial mesenchymal-epithelial transition of human pancreatic cancer cells via the PTEN/PI3K/Akt pathway

Xiao‑Ping Yi, Tong Han, Yi‑Xiong Li, Xue‑Ying Long, Wen‑Zheng Li

Pages: 601-608 Published online on: 20 February 2015
Article

Ginsenoside Rg3 sensitizes human non‑small cell lung cancer cells to γ-radiation by targeting the nuclear factor-κB pathway

Lei Wang, Xiankui Li, Yi‑Min Song, Bin Wang, Fu‑Rui Zhang, Rui Yang, Hua‑Qi Wang, Guo‑Jun Zhang

Pages: 609-614 Published online on: 27 February 2015
Article

Identification and validation of reference genes for the detection of serum microRNAs by reverse transcription‑quantitative polymerase chain reaction in patients with bladder cancer

Lishui Wang, Yimin Liu, Lutao Du, Juan Li, Xiumei Jiang, Guixi Zheng, Ailin Qu, Haiyan Wang, Lili Wang, Xin Zhang, Hui Liu, Hongwei Pan, Yongmei Yang, Chuanxin Wang

Pages: 615-622 Published online on: 04 March 2015
Article

Molecular mechanism underlying the anticancer effect of simvastatin on MDA‑MB‑231 human breast cancer cells

Yuan‑Yuan Shen, Yuan Yuan, Ying‑Ying Du, Yue‑Yin Pan

Pages: 623-630 Published online on: 04 March 2015
Article
Article

Activation of notch signaling mediates the induction and maintenance of mechanical allodynia in a rat model of neuropathic pain

Keliang Xie, Yingping Jia, Ying Hu, Yanyan Sun, Lichao Hou, Guolin Wang

Pages: 639-644 Published online on: 20 February 2015
Article

Angiotensin II promotes melanogenesis via angiotensin II type 1 receptors in human melanocytes

Li‑Hong Liu, Xin Fan, Hai‑Tao Li, Xu‑Xi An, Rong‑Ya Yang

Pages: 651-656 Published online on: 05 March 2015
Article

Orostachys japonicus inhibits the expression of MMP-2 and MMP-9 mRNA and modulates the expression of iNOS and COX-2 genes in human PMA-differentiated THP-1 cells via inhibition of NF-κB and MAPK activation

Young Il Kim, Seung‑Won Park, Yeo‑Kwang Yoon, Kyung‑Wook Lee, Jang‑Hoon Lee, Hong‑Jung Woo, Youngchul Kim

Pages: 657-662 Published online on: 10 March 2015
Article

Synergistic effects of oxyresveratrol in conjunction with antibiotics against methicillin-resistant Staphylococcus aureus

Dae‑Ki Joung, Sung‑Hoon Choi, Ok‑Hwa Kang, Sung‑Bae Kim, Su‑Hyun Mun, Yun‑Soo Seo, Da-Hye Kang, Ryong Gong, Dong‑Won Shin, Youn-Chul Kim, Dong‑Yeul Kwon

Pages: 663-667 Published online on: 12 February 2015
Article

MicroRNA-183/182/96 cooperatively regulates the proliferation of colon cancer cells

Qingquan Zhang, Wei Ren, Bin Huang, Liang Yi, Hongtao Zhu

Pages: 668-674 Published online on: 18 February 2015
Article

Protective role of isoflurane pretreatment in rats with focal cerebral ischemia and the underlying molecular mechanism

Zhibin Xiao, Pengcheng Ren, Yang Chao, Qianyun Wang, Jianke Kuai, Miaomiao Lv, Lei Chen, Changjun Gao, Xude Sun

Pages: 675-683 Published online on: 04 March 2015
Article

Beneficial effects of tripterygium glycosides tablet on biomarkers in patients with ankylosing spondylitis

Wei Ji, Yajun Chen, Xia Zhao, Yunke Guo, Lingyu Zhong, Honggang Li, Dan Wang, Yanna Song

Pages: 684-690 Published online on: 06 March 2015
Article

Role of p53β in the inhibition of proliferation of gastric cancer cells expressing wild-type or mutated p53

Wansheng Ji, Jingrong Ma, Hongmei Zhang, Hua Zhong, Lei Li, Na Ding, Jianxin Jiao, Zhixing Gao

Pages: 691-695 Published online on: 18 February 2015
Article

Antioxidant activity is required for the protective effects of cyclophilin A against oxidative stress

Kiyoon Kim, In Kyung Oh, Kyung Sik Yoon, Joohun Ha, Insug Kang, Wonchae Choe

Pages: 712-718 Published online on: 26 February 2015
Article

Combination of cytokinin and auxin induces apoptosis, cell cycle progression arrest and blockage of the Akt pathway in HeLa cells

Liwei Zhao, Peng Liu, Guangqin Guo, Li Wang

Pages: 719-727 Published online on: 04 March 2015
Article

Regulation of the expression of claudin 23 by the enhancer of zeste 2 polycomb group protein in colorectal cancer

Natalia Maryan, Malgorzata Statkiewicz, Michal Mikula, Krzysztof Goryca, Agnieszka Paziewska, Adriana Strzałkowska, Michalina Dabrowska, Mateusz Bujko, Jerzy Ostrowski

Pages: 728-736 Published online on: 19 February 2015
Article

Immunohistochemical profile of cytokines and growth factors expressed in vestibular schwannoma and in normal vestibular nerve tissue

Samanta Taurone, Enrica Bianchi, Giuseppe Attanasio, Cira Di Gioia, Rocco Ierinó, Cecilia Carubbi, Daniela Galli, Francesco Saverio Pastore, Felice Giangaspero, Roberto Filipo, Christian Zanza, Marco Artico

Pages: 737-745 Published online on: 04 March 2015
Article

Use of the disulfiram/copper complex for breast cancer chemoprevention in MMTV‑erbB2 transgenic mice

Yanhui Yang, Qian Deng, Xiaoshan Feng, Junjun Sun

Pages: 746-752 Published online on: 04 March 2015
Article

Vasoactive intestinal peptide induces CD14+HLA-DR‑/low myeloid-derived suppressor cells in gastric cancer

Gang Li, Ke Wu, Kaixiong Tao, Xiaoming Lu, Jianhua Ma, Zhengqiang Mao, Hang Li, Liang Shi, Jing Li, Yanfeng Niu, Fan Xiang, Guobin Wang

Pages: 760-768 Published online on: 18 February 2015
Article

Antiproliferative effects of anastrozole on MCF‑7 human breast cancer cells in vitro are significantly enhanced by combined treatment with testosterone undecanoate

Rong Chen, Junwei Cui, Qinqin Wang, Peng Li, Xiaoling Liu, Hui Hu, Wei Wei

Pages: 769-775 Published online on: 04 March 2015
Review Open Access

Lipid metabolism disorders and bone dysfunction - interrelated and mutually regulated (Review)

Li Tian, Xijie Yu

Pages: 783-794 Published online on: 11 March 2015
Review

Positive and negative regulators of the metallothionein gene (Review)

Shinichiro Takahashi

Pages: 795-799 Published online on: 09 March 2015
Article Open Access

Identification of biomarkers regulated by rexinoids (LGD1069, LG100268 and Ro25-7386) in human breast cells using Affymetrix microarray

Hye‑Sook Seo, Jong‑Kyu Woo, Yong Cheol Shin, Seong‑Gyu Ko

Pages: 800-818 Published online on: 12 March 2015
Article Open Access

Differentiation of human umbilical cord mesenchymal stem cells into germ-like cells in mouse seminiferous tubules

Hui Chen, Qiu‑Ling Tang, Xiao‑Ying Wu, Li‑Chun Xie, Li‑Min Lin, Gu‑Yu Ho, Lian Ma

Pages: 819-828 Published online on: 23 March 2015
Article Open Access

Effects of silencing the ATP-binding cassette protein E1 gene by electroporation on the proliferation and migration of EC109 human esophageal cancer cells

Xiao-Rui Li, Liu-Zhong Yang, Xiao-Qing Huo, Ying Wang, Qing-Hui Yang, Qing-Qin Zhang

Pages: 837-842 Published online on: 19 March 2015
Article Open Access

High glucose promotes gastric cancer chemoresistance in vivo and in vitro

Wei Zhao, Rui Chen, Mei Zhao, Liang Li, Lin Fan, Xiang‑Ming Che

Pages: 843-850 Published online on: 20 March 2015
Article Open Access

Transforming growth factor‑β, insulin‑like growth factor I/insulin‑like growth factor I receptor and vascular endothelial growth factor‑A: Prognostic and predictive markers in triple‑negative and non‑triple‑negative breast cancer

Abeer Bahhnassy, Marwa Mohanad, Sabry Shaarawy, Manal F. Ismail, Ahmed El‑Bastawisy, Abeer M. Ashmawy, Abdel‑Rahman Zekri

Pages: 851-864 Published online on: 27 March 2015
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Trop2 inhibition suppresses the proliferation and invasion of laryngeal carcinoma cells via the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway

Xu‑Dong Wang, Qiang Wang, Xiao‑Lin Chen, Jian‑Fei Huang, Yong Yin, Peng Da, Hao Wu

Pages: 865-870 Published online on: 13 March 2015
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Spindle cell oncocytoma of the adenohypophysis: Two case reports and a review of the literature

Qingchun Mu, Jinlu Yu, Limei Qu, Xitong Hu, Haijun Gao, Pengfei Liu, Xu Zheng, Yuxue Sun, Haiyan Huang

Pages: 871-876 Published online on: 12 March 2015
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Gliotoxin potentiates osteoblast differentiation by inhibiting nuclear factor-κB signaling

Guangye Wang, Xiaohai Zhang, Baoqing Yu, Ke Ren

Pages: 877-884 Published online on: 20 March 2015
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Integrated microRNA-mRNA analysis revealing the potential roles of microRNAs in tongue squamous cell cancer

Xiao‑Li Zhou, Jun‑Hua Wu, Xin‑Juan Wang, Fu‑Jun Guo

Pages: 885-894 Published online on: 11 March 2015
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Overexpression of caudal type homeobox transcription factor 2 inhibits the growth of the MGC‑803 human gastric cancer cell line in vivo

Weiyuan Wei, Lei Li, Xiaotong Wang, Linhai Yan, Wenlong Cao, Zexu Zhan, Xiaoshi Zhang, Han Yu, Yubo Xie, Qiang Xiao

Pages: 905-912 Published online on: 04 March 2015
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Efficient labeling in vitro with non-ionic gadolinium magnetic resonance imaging contrast agent and fluorescent transfection agent in bone marrow stromal cells of neonatal rats

Ying‑Qin Li, Ying Tang, Rao Fu, Qiu‑Hua Meng, Xue Zhou, Ze‑Min Ling, Xiao Cheng, Su‑Wei Tian, Guo‑Jie Wang, Xue‑Guo Liu, Li‑Hua Zhou

Pages: 913-920 Published online on: 23 March 2015
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Implication of microRNA regulation in para-phenylenediamine-induced cell death and senescence in normal human hair dermal papilla cells

Ok‑Kyu Lee, Hwa Jun Cha, Myung Joo Lee, Kyung Mi Lim, Jae Wook Jung, Kyu Joong Ahn, In‑Sook An, Sungkwan An, Seunghee Bae

Pages: 921-936 Published online on: 13 March 2015
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An integrated analysis of the effects of microRNA and mRNA on esophageal squamous cell carcinoma

Yong Yang, Dianbo Li, Yang Yang, Gening Jiang

Pages: 945-952 Published online on: 27 March 2015
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Enterovirus 71 induces apoptosis of SH‑SY5Y human neuroblastoma cells through stimulation of endogenous microRNA let-7b expression

Xiling Du, Haipeng Wang, Fuhui Xu, Yongyi Huang, Zhixue Liu, Te Liu

Pages: 953-959 Published online on: 13 March 2015
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RNA silencing of integrin-linked kinase increases the sensitivity of the A549 lung cancer cell line to cisplatin and promotes its apoptosis

Xiaozhen Zhao, Zhenye Xu, Zhongqi Wang, Zhonghua Wu, Yabin Gong, Lijuan Zhou, Yi Xiang

Pages: 960-966 Published online on: 11 March 2015
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Expression signatures of long non-coding RNAs in early brain injury following experimental subarachnoid hemorrhage

Bingjie Zheng, Huailei Liu, Ruke Wang, Shancai Xu, Yaohua Liu, Kaikai  Wang, Xu Hou, Chen Shen, Jianing Wu, Xin Chen, Pei Wu, Guang Zhang, Zhiyong Ji, Hongyu Wang, Yao Xiao, Jianyi Han, Huaizhang Shi, Shiguang Zhao

Pages: 967-973 Published online on: 11 March 2015
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Association of neonatal necrotizing enterocolitis with myeloid differentiation-2 and GM2 activator protein genetic polymorphisms

Wei Zhou, Weiming Yuan, Longguang Huang, Ping Wang, Xiao Rong, Juan Tang

Pages: 974-980 Published online on: 17 March 2015
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Gene expression changes in human mesenchymal stem cells from patients with osteoporosis

Lianyong Liu, Qingyun Zhu, Jingnan Wang, Qian Xi, Hongling Zhu, Mingjun Gu

Pages: 981-987 Published online on: 19 March 2015
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Ameliorative effects of Gualou Guizhi decoction on inflammation in focal cerebral ischemic-reperfusion injury

Yuqin Zhang, Shengnan Zhang, Huang Li, Mei Huang, Wei Xu, Kedan Chu, Lidian Chen, Xianwen Chen

Pages: 988-994 Published online on: 19 March 2015
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Impact of Brachyury on epithelial-mesenchymal transitions and chemosensitivity in non-small cell lung cancer

Ke Xu, Bin Liu, Yongyu Liu

Pages: 995-1001 Published online on: 13 February 2015
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Somatostatin prevents lipopolysaccharide‑induced neurodegeneration in the rat substantia nigra by inhibiting the activation of microglia

Lijuan Bai, Xique Zhang, Xiaohong Li, Na Liu, Fan Lou, Honglei Ma, Xiaoguang Luo, Yan Ren

Pages: 1002-1008 Published online on: 13 March 2015
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Calcitriol ameliorates renal damage in a pre‑established proteinuria model

Edgar Maquigussa, Carine P. Arnoni, Luciana G. Pereira, Mirian A. Boim

Pages: 1009-1015 Published online on: 27 March 2015
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MicroRNA-218 and microRNA-520a inhibit cell proliferation by downregulating E2F2 in hepatocellular carcinoma

Ye Dong, Jianjun Zou, San Su, Huiyi Huang, Yanzhen Deng, Birong Wang, Weidong Li

Pages: 1016-1022 Published online on: 19 March 2015
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Apoptin-modified human mesenchymal stem cells inhibit growth of lung carcinoma in nude mice

Jingchun Du, Yanling Zhang, Chun Xu, Xia Xu

Pages: 1023-1029 Published online on: 17 March 2015
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cDNA microarray analysis of the effect of cantharidin on DNA damage, cell cycle and apoptosis-associated gene expression in NCI-H460 human lung cancer cells in vitro

Te‑Chun Hsia, Chien‑Chih Yu, Shu‑Chun Hsu, Nou‑Ying Tang, Hsu‑Feng Lu, Chun‑Shu Yu, Shin‑Hwar Wu, Jaung‑Geng Lin, Jing‑Gung Chung

Pages: 1030-1042 Published online on: 24 March 2015
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Salubrinal protects cardiomyocytes against apoptosis in a rat myocardial infarction model via suppressing the dephosphorylation of eukaryotic translation initiation factor 2α

Rui‑Jun Li, Kun‑Lun He, Xin Li, Li‑Li Wang, Chun‑Lei Liu, Yun‑Yun He

Pages: 1043-1049 Published online on: 18 March 2015
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Overexpression of N‑myc downstream‑regulated gene 1 inhibits human glioma proliferation and invasion via phosphoinositide 3‑kinase/AKT pathways

Wei Ma, Meng Na, Chongyang Tang, Haiyang Wang, Zhiguo Lin

Pages: 1050-1058 Published online on: 13 March 2015
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Epigenetic modification and preliminary investigation of the mechanism of the immune evasion of HL-60 cells

Jin Hong Liu, Yong Mei Bian, Yi Xie, Dao Pei Lu

Pages: 1059-1065 Published online on: 20 March 2015
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Lifen Dai, Haiying Wu, Shan Yu, Hongbin Zhao, Lanjie Xue, Ming Xu, Zhiqiang Shen, Min Hu

Pages: 1066-1074 Published online on: 26 March 2015
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Litsea japonica extract inhibits neuronal apoptosis and the accumulation of advanced glycation end products in the diabetic mouse retina

Junghyun Kim, Chan‑Sik Kim, Yun Mi Lee, Eunjin Sohn, Kyuhyung Jo, Jin Sook Kim

Pages: 1075-1081 Published online on: 24 March 2015
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Sevoflurane ameliorates intestinal ischemia-reperfusion-induced lung injury by inhibiting the synergistic action between mast cell activation and oxidative stress

Chenfang Luo, Dongdong Yuan, Weicheng Zhao, Huixin Chen, Gangjian Luo, Guangjie Su, Ziqing Hei

Pages: 1082-1090 Published online on: 23 March 2015
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Connective tissue growth factor stimulates the proliferation, migration and differentiation of lung fibroblasts during paraquat‑induced pulmonary fibrosis

Zhizhou Yang, Zhaorui Sun, Hongmei Liu, Yi Ren, Danbing Shao, Wei Zhang, Jinfeng Lin, Joy Wolfram, Feng Wang, Shinan Nie

Pages: 1091-1097 Published online on: 24 March 2015
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Agmatine protects Müller cells from high‑concentration glucose‑induced cell damage via N‑methyl‑D‑aspartic acid receptor inhibition

Ning Han, Li Yu, Zhidu Song, Lifu Luo, Yazhen Wu

Pages: 1098-1106 Published online on: 24 March 2015
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Knockdown of ubiquitin protein ligase E3A affects proliferation and invasion, and induces apoptosis of breast cancer cells through regulation of annexin A2

Xiaofang Zhou, Shishan Deng, Hai Liu, Yang Liu, Zhengwei Yang, Tianyong Xing, Baoqian Jing, Xiaoming Zhang

Pages: 1107-1113 Published online on: 26 March 2015
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Antineoplastic effect of a novel chemopreventive agent, neokestose, on the Caco-2 cell line via inhibition of expression of nuclear factor-κB and cyclooxygenase-2

Shun‑Mei Lee, Jan‑Yi Chang, Jiann‑Shing Wu, Dey‑Chyi Sheu

Pages: 1114-1118 Published online on: 18 March 2015
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Ehlers-Danlos syndrome type IV is associated with a novel G984R COL3A1 mutation

Yao Deng, Shijie Wei, Shijun Hu, Jinlan Chen, Zhiping Tan, Yifeng Yang

Pages: 1119-1124 Published online on: 13 March 2015
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Verifying the markers of ovarian cancer using RNA‑seq data

Tianfeng Liu, Nina Yu, Feng Ding, Surong Wang, Shihong Li, Xiaofei Zhang, Xiangxiu Sun, Ying Chen, Peishu Liu

Pages: 1125-1130 Published online on: 13 March 2015
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Vaccarin promotes endothelial cell proliferation in association with neovascularization in vitro and in vivo

Fengshan Xie, Lei Feng, Weiwei Cai, Yuyu Qiu, Yanling  Liu, Yue Li, Bin Du, Liying Qiu

Pages: 1131-1136 Published online on: 18 March 2015
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Generation of transgenic fibroblasts producing doxycycline‑inducible human interferon‑α or erythropoietin for a bovine mammary bioreactor

Hee Young Kang, Eui‑Ju Hong, Kyu‑Chan Hwang, Nam‑Hyung Kim, Woo‑Suk Hwang, Eui‑Bae Jeung

Pages: 1137-1144 Published online on: 13 March 2015
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Acetyl‑l‑carnitine prevents homocysteine‑induced suppression of Nrf2/Keap1 mediated antioxidation in human lens epithelial cells

Shui‑Ping Yang, Xiu‑Zhen Yang, Guo‑Ping Cao

Pages: 1145-1150 Published online on: 13 March 2015
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Curcumin triggers apoptosis via upregulation of Bax/Bcl-2 ratio and caspase activation in SW872 human adipocytes

Lin Zhu, Ming Bao Han, Yuan Gao, Huan Wang, Ling Dai, Ying Wen, Li Xin Na

Pages: 1151-1156 Published online on: 06 March 2015
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Antibody microarray profiling of osteosarcoma cell serum for identifying potential biomarkers

Zi-Qiang Zhu, Jin-Shan Tang, Duan Gang, Ming-Xing Wang, Jian-Qiang Wang, Zhou Lei, Zhou Feng, Ming-Liang Fang, Lin Yan

Pages: 1157-1162 Published online on: 24 March 2015
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MicroRNA‑423‑5p targets O‑GlcNAc transferase to induce apoptosis in cardiomyocytes

Peng Luo, Tao He, Rongjian Jiang, Gang Li

Pages: 1163-1168 Published online on: 13 March 2015
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Ischemic postconditioning regulates cardiomyocyte autophagic activity following ischemia/reperfusion injury

Liang Guo, Jun‑Mei Xu, Xiao‑Ye Mo

Pages: 1169-1176 Published online on: 24 March 2015
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Clinicopathological significance of cytoplasmic transducer of ErbB2. 1 expression in gastric cancer

Su‑Qing Zhang, Ke‑Kang Sun, Xiao‑Yang Wu, Ning Zhong, Hua Zhao, De‑Chun Li

Pages: 1177-1182 Published online on: 11 March 2015
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Apoptosis induced by sonodynamic therapy in human osteosarcoma cells in vitro

Xing Liu, Wei Li, Shuo Geng, Qing‑Gang Meng, Zheng‑Gang Bi

Pages: 1183-1188 Published online on: 12 March 2015
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Nitrogen permease regulator‑like 2 enhances sensitivity to oxaliplatin in colon cancer cells

Ming‑Na Liu, Ai‑Yun Liu, Ya‑Ju Du, Feng‑Hua Pei, Xin‑Hong Wang, Jing Chen, Dan Liu, Bing‑Rong Liu

Pages: 1189-1196 Published online on: 13 March 2015
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Analysis of the microRNA expression profile of normal human dermal papilla cells treated with 5α-dihydrotestosterone

Myung Joo Lee, Hwa Jun Cha, Kyung Mi Lim, Ok‑Kyu Lee, Seunghee Bae, Chun‑Ho Kim, Kee‑Ho Lee, Yu Na Lee, Kyu Joong Ahn, Sungkwan An

Pages: 1205-1212 Published online on: 12 March 2015
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Design, expression and characterization of single chain Fv, Mms13 and the single chain Fv‑mms13 fusion protein

Deng Kong, Xiaoke Wang, Xiaohong Wang, Xueyun Wang, Xiaoli Chen, Guoqiang Ji, Xinhua Fu, Shouxun Wang

Pages: 1213-1218 Published online on: 27 March 2015
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Identification of KRAS and PIK3CA but not BRAF mutations in patients with gastric cancer

Weipeng Lu, Hong Wei, Mei Li, Hai Wang, Lina Liu, Qiuping Zhang, Lisha Liu, Shen Lu

Pages: 1219-1224 Published online on: 23 March 2015
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Comparative analysis of the influence of Fructus Ligustri Lucidi on a rat lumbar disc herniation model

Ya‑Xin Han, Dong Liang, Xiao‑Rui Han, De‑Yong Liang

Pages: 1225-1232 Published online on: 24 March 2015
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Arsenic trioxide inhibits breast cancer cell growth via microRNA‑328/hERG pathway in MCF‑7 cells

Ying Wang, Leqiu Wang, Changhao Yin, Baizhu An, Yankun Hao, Tao Wei, Li Li, Gaochen Song

Pages: 1233-1238 Published online on: 27 March 2015
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Computational networks of activating transcription factor 3 gene in Huh7 cell lines and hepatitis C virus-infected Huh7 cell lines

Jingkun Liu, Bing Wang, Wenjun Wang, Mingzhu Sun, Yapping Li, Xiaoli Jia, Song Zhai, Shuangsuo Dang

Pages: 1239-1246 Published online on: 26 March 2015
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3,3'-Diindolylmethane attenuates cardiac H9c2 cell hypertrophy through 5'-adenosine monophosphate-activated protein kinase-α

Jing Zong, Qing‑Qing Wu, Heng Zhou, Jie‑Yu Zhang, Yuan Yuan, Zhou‑Yan Bian, Wei Deng, Jia Dai, Fang‑Fang Li, Man Xu, Yi Fang, Qi‑Zhu Tang

Pages: 1247-1252 Published online on: 20 March 2015
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Curcuma zedoaria (Berg.) Rosc. essential oil and paclitaxel synergistically enhance the apoptosis of SKOV3 cells

Yunxiao Zhou, Jie Shen, Liqun Xia, Yanli Wang

Pages: 1253-1257 Published online on: 11 March 2015
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Upregulated microRNA-214 enhances cardiac injury by targeting ITCH during coxsackievirus infection

Zhi‑Gang Chen, Hui Liu, Jun‑Biao Zhang, Shao‑Li Zhang, Li‑Hua Zhao, Wan‑Qian Liang

Pages: 1258-1264 Published online on: 24 March 2015
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Somatic mutations in myeloid cell leukemia‑1 contribute to the pathogenesis of glioma by prolonging its half‑life

Xiupeng Lv, Guang Tan, Yiqun Yao, Li Lv, Xiaoqin Deng, Lei Dong, Shuang Li, Linlin Li, Yinghui Xu

Pages: 1265-1271 Published online on: 13 March 2015
Article

Blood-brain barrier permeability of Gualou Guizhi granules and neuroprotective effects in ischemia/reperfusion injury

Huang Li, Miao Ye, Yuqin Zhang, Mingqing Huang, Wei Xu, Kedan Chu, Lidian Chen, Jinhua Que

Pages: 1272-1278 Published online on: 20 March 2015
Article

High-mobility group nucleosome-binding domain 2 protein inhibits the invasion of Klebsiella pneumoniae into mouse lungs in vivo

Shuang Zheng, Laibin Ren, Heng Li, Xiaofei Shen, Xiaolong Yang, Na Li, Xinyuan Wang, Xiaojuan Guo, Xiaoying Wang, Ning Huang

Pages: 1279-1285 Published online on: 10 March 2015
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VP22 mediates intercellular trafficking and enhances the in vitro antitumor activity of PTEN

Xian Yu, Zhengmin Xu, Jun Lei, Tingting Li, Yan Wang

Pages: 1286-1290 Published online on: 18 March 2015
Article

Anti-profibrotic effects of artesunate on bleomycin-induced pulmonary fibrosis in Sprague Dawley rats

Changming Wang, Xiuping Xuan, Wenmin Yao, Guojin Huang, Junfei Jin

Pages: 1291-1297 Published online on: 17 March 2015
Article

Golgi phosphoprotein 3 expression predicts poor prognosis in patients with prostate cancer undergoing radical prostatectomy

Longyang Zhang, Feng Guo, Xinghua Gao, Yanlin Wu

Pages: 1298-1304 Published online on: 09 March 2015
Article

Cbl participates in shikonin-induced apoptosis by negatively regulating phosphoinositide 3-kinase/protein kinase B signaling

Dan Qu, Xiao‑Man Xu, Meng Zhang, Ting‑Shu Jiang, Yi Zhang, Sheng‑Qi Li

Pages: 1305-1313 Published online on: 18 March 2015
Article

Zanthoxylum schinifolium leaf ethanol extract inhibits adipocyte differentiation through inactivation of the extracellular signal regulated kinase and phosphoinositide 3-kinase/Akt signaling pathways in 3T3-L1 pre-adipocytes

Eun‑Ok Choi, Cheol Park, Soon Shik Shin, Eun‑Ju Cho, Byung Woo Kim, Jin Ah Hwang, Hye‑Jin Hwang, Yung Hyun Choi

Pages: 1314-1320 Published online on: 10 March 2015
Article

Anti-inflammatory effects of Gualou Guizhi decoction in transient focal cerebral ischemic brains Corrigendum in /mmr/12/3/3998

Hai Xia Hu, Ru Hui Lin, Xiao Qin Zhu, Zuan Fang Li, Li Dian Chen

Pages: 1321-1327 Published online on: 19 March 2015
Article

DNA-dependent protein kinase catalytic subunit inhibitor reverses acquired radioresistance in lung adenocarcinoma by suppressing DNA repair

Yong Li, Hang Li, Wen Peng, Xin‑Yun He, Min Huang, Dong Qiu, Ying‑Bo Xue, Liang Lu

Pages: 1328-1334 Published online on: 18 March 2015
Article

Extracts of Scutellariae Radix inhibit low-density lipoprotein oxidation and the lipopolysaccharide-induced macrophage inflammatory response

Ohn Soon Kim, Chang‑Seob Seo, Yeji Kim, Hyeun‑Kyoo Shin, Hyekyung Ha

Pages: 1335-1341 Published online on: 17 March 2015
Article

Carbamylated low-density lipoprotein attenuates glucose uptake via a nitric oxide-mediated pathway in rat L6 skeletal muscle cells

Hye‑Jung Choi, Kyoung Jae Lee, Eun Ah Hwang, Kyo‑Cheol Mun, Eunyoung Ha

Pages: 1342-1346 Published online on: 13 March 2015
Article

Curcumin protects renal tubular epithelial cells from high glucose-induced epithelial-to-mesenchymal transition through Nrf2-mediated upregulation of heme oxygenase-1

Xiuli Zhang, Dan Liang, Lin Guo, Wei Liang, Yan Jiang, Hongjuan Li, Yue Zhao, Shumin Lu, Zhi‑Hong Chi

Pages: 1347-1355 Published online on: 27 March 2015
Article

Fetuin-A 742 (C/T) and 766 (C/G) polymorphic sites are associated with increased risk of myocardial infarction in older patients (≥40 years of age)

Ajda Coker‑Gurkan, Deniz Coskun, Elif Damla Arisan, Pinar Obakan, Özer Soylu, Narcin Palavan Unsal

Pages: 1356-1362 Published online on: 20 March 2015
Article

A novel molecular probe 131I-K237 targeting tumor angiogenesis in human prostate cancer xenografts

Qian Zhao, Yu Zhang, Jun Guo, Juan Li

Pages: 1363-1367 Published online on: 18 March 2015
Article

Modulatory role of resveratrol on cytotoxic activity of cisplatin, sensitization and modification of cisplatin resistance in colorectal cancer cells

Abdel‑Moneim M. Osman, Hamdan S. Al‑Malki, Sameer E. Al‑Harthi, Amr A. El‑Hanafy, Hassan M. Elashmaoui, Mohamed F. Elshal

Pages: 1368-1374 Published online on: 19 March 2015
Article

Regulation of the oncogenic function of distal-less 4 by microRNA-122 in hepatocellular carcinoma

Xu-Hua Xie, Xiao-Pei Xu, Chang-Yu Sun, Zu-Jiang Yu

Pages: 1375-1380 Published online on: 27 March 2015
Article

CD9 modulates proliferation of human glioblastoma cells via epidermal growth factor receptor signaling

Gong‑Ping Wang, Xiao‑Fang Han

Pages: 1381-1386 Published online on: 10 March 2015
Article

Angiotensin‑(1‑7) stimulates cholesterol efflux from angiotensin II‑treated cholesterol‑loaded THP‑1 macrophages through the suppression of p38 and c‑Jun N‑terminal kinase signaling

Hui‑Yu Yang, Yun‑Fei Bian, Chuan‑Shi Xiao, Bin Liang, Nana Zhang, Fen Gao, Zhi‑Ming Yang

Pages: 1387-1392 Published online on: 13 March 2015
Article

Investigating polymorphisms in membrane-associated transporter protein SLC45A2, using sucrose transporters as a model

Anke Reinders, John M. Ward

Pages: 1393-1398 Published online on: 10 March 2015
Article

Upregulated microRNA-16 as an oncogene in renal cell carcinoma

Duqun Chen, Yifan Li, Zuhu Yu, Zhengming Su, Wenshui Yu, Yuchi Li, Shangqi Yang, Yaoting Gui, Liangchao Ni, Yongqing Lai

Pages: 1399-1404 Published online on: 17 March 2015
Article

Social defeat stress promotes tumor growth and angiogenesis by upregulating vascular endothelial growth factor/extracellular signal-regulated kinase/matrix metalloproteinase signaling in a mouse model of lung carcinoma

Xiao Wu, Bao‑Jun Liu, Shumeng Ji, Jing‑Feng Wu, Chang‑Qing Xu, Yi‑Jie Du, Xiao‑Fang You, Bei Li, Jing‑Jing Le, Hai‑Lin Xu, Xiao‑Hong Duan, Jing‑Cheng Dong

Pages: 1405-1412 Published online on: 27 March 2015
Article

Upregulation of microRNA‑492 induced by epigenetic drug treatment inhibits the malignant phenotype of clear cell renal cell carcinoma in vitro

Aibing Wu, Kunpeng Wu, Mingchun Li, Lingli Bao, Xiang Shen, Shunjun Li, Jinmei Li, Zhixiong Yang

Pages: 1413-1420 Published online on: 26 March 2015
Article

Enoyl-coenzyme A hydratase short chain 1 silencing attenuates the proliferation of hepatocellular carcinoma by inhibiting epidermal growth factor signaling in vitro and in vivo

Bi-Yun Lin, Chuan-Xing Xiao, Wen-Xiu Zhao, Li Xiao, Xu Chen, Ping Li, Xiao-Min Wang

Pages: 1421-1428 Published online on: 09 March 2015
Article

Apoptosis of HL-60 human leukemia cells induced by Asiatic acid through modulation of B-cell lymphoma 2 family proteins and the mitogen-activated protein kinase signaling pathway

Qiuling Wu, Tingting Lv, Yan Chen, Lu Wen, Junli Zhang, Xudong Jiang, Fang Liu

Pages: 1429-1434 Published online on: 24 March 2015
Article

DNA methyltransferase 3, a target of microRNA-29c, contributes to neuronal proliferation by regulating the expression of brain-derived neurotrophic factor

Guoshuai Yang, Yanmin Song, Xiaoyan Zhou, Yidong Deng, Tao Liu, Guohu Weng, Dan Yu, Suyue Pan

Pages: 1435-1442 Published online on: 23 March 2015
Article

Violacein induces p44/42 mitogen-activated protein kinase‑mediated solid tumor cell death and inhibits tumor cell migration

Toral Mehta, Koen Vercruysse, Terrance Johnson, Anthony Okechukwu Ejiofor, Elbert Myles, Quincy Antoine Quick

Pages: 1443-1448 Published online on: 20 March 2015
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Article

Inhibition of Forkhead box protein M1 by thiostrepton increases chemosensitivity to doxorubicin in T-cell acute lymphoblastic leukemia

Jian‑Yong Wang, Xiu‑Hong Jia, Hai‑Yan Xing, You‑Jie Li, Wen‑Wen Fan, Na Li, Shu‑Yang Xie

Pages: 1457-1464 Published online on: 11 March 2015
Article

Artesunate induces apoptosis and inhibits growth of Eca109 and Ec9706 human esophageal cancer cell lines in vitro and in vivo

Liang Liu, Lian‑Fu Zuo, Jing Zuo, Jing Wang

Pages: 1465-1472 Published online on: 20 March 2015
Article

Resveratrol suppresses vascular endothelial growth factor secretion via inhibition of CXC-chemokine receptor 4 expression in ARPE-19 cells

Hyemin Seong, Jinhyun Ryu, Joo Yeon Jeong, In Young Chung, Yong‑Seop Han, Soo Hyun Hwang, Jong Moon Park, Sang Soo Kang, Seong Wook Seo

Pages: 1479-1484 Published online on: 20 March 2015
Article

Ophiopogonin‑D suppresses MDA‑MB‑435 cell adhesion and invasion by inhibiting matrix metalloproteinase‑9

Yuanyuan Zhang, Yuwei Han, Kefeng Zhai, Minhui Sun, Jihua Liu, Boyang Yu, Junping Kou

Pages: 1493-1498 Published online on: 24 March 2015
Article

Tumor necrosis factor-like weak inducer of apoptosis regulates particle-induced inflammatory osteolysis via the p38 mitogen-activated protein kinase signaling pathway

Zhiqiang Zhang, Yongchao Fang, Qiang Wang, Yu Sun, Chuanzhi Xiong, Li Cao, Beiyue Wang, Nirong Bao, Jianning Zhao

Pages: 1499-1505 Published online on: 23 March 2015
Article

Paclitaxel resistance in MCF-7/PTX cells is reversed by paeonol through suppression of the SET/phosphatidylinositol 3-kinase/Akt pathway

Weipeng Zhang, Jiangxia Cai, Siying Chen, Xiaowei Zheng, Sasa Hu, Weihua Dong, Jun Lu, Jianfeng Xing, Yalin Dong

Pages: 1506-1514 Published online on: 11 March 2015
Article

Emerging role of microRNA-27a in human malignant glioma cell survival via targeting of prohibitin

Wei Chen, Jun Qi, Gang Bao, Tuo Wang, Chang‑Wang Du, Mao‑De Wang

Pages: 1515-1523 Published online on: 12 March 2015
Article

Identification of active ingredients in Wuzhuyu decoction improving migraine in mice by spectral efficiency association

Xueqiang Pan, Manyuan Wang, Yanchuan Wu, Xuran Lu, Yawen Shang, Yongsong Xu, Yongsong Zhai, Jing Li, Zhaoxia Li, Muxin Gong

Pages: 1524-1534 Published online on: 18 March 2015
Article

MicroRNA-509-3p inhibits cancer cell proliferation and migration by targeting the mitogen-activated protein kinase kinase kinase 8 oncogene in renal cell carcinoma

Zhengming Su, Duqun Chen, Enpu Zhang, Yifan Li, Zuhu Yu, Min Shi, Zhimao Jiang, Liangchao Ni, Shangqi Yang, Yaoting Gui, Jiongxian Ye, Yongqing Lai

Pages: 1535-1543 Published online on: 17 March 2015
Article

Effects of glucose-dependent insulinotropic polypeptide receptor knockout and a high-fat diet on cognitive function and hippocampal gene expression in mice Erratum in /10.3892/mmr.2015.4078

Rachael R. Lennox, Charlotte Moffett, David W. Porter, Nigel Irwin, Victor A. Gault, Peter R. Flatt

Pages: 1544-1548 Published online on: 06 March 2015
Article

MicroRNA-146b-5p inhibits the growth of gallbladder carcinoma by targeting epidermal growth factor receptor

Jingli Cai, Lubai Xu, Zhenzhai Cai, Jisheng Wang, Bing Zhou, Hai Hu

Pages: 1549-1555 Published online on: 10 March 2015
Article

Evaluation of the effects of Angelicae dahuricae radix on the morphology and viability of mesenchymal stem cells

Su‑Hyeon Jeong, Bo‑Bae Kim, Ji‑Eun Lee, Youngkyung Ko, Jun‑Beom Park

Pages: 1556-1560 Published online on: 09 March 2015
Article

MicroRNA-21 promotes osteogenic differentiation by targeting small mothers against decapentaplegic 7

Hongqiu Li, Feng Yang, Zhe Wang, Qin Fu, A Liang

Pages: 1561-1567 Published online on: 17 March 2015
Article

Association study of polymorphisms in interferon-γ receptor genes with the risk of pulmonary tuberculosis

Joong‑Gon Shin, Byung Lae Park, Lyoung Hyo Kim, Suhg Namgoong, Ji On Kim, Hun Soo Chang, Jong Sook Park, An Soo Jang, Sung Woo Park, Do Jin Kim, Ki Up Kim, Yang Gee Kim, Soo‑Taek Uh, Ki Hyun Seo, Young Hoon Kim, Insong Koh, Choon Sik Park, Hyoung Doo Shin

Pages: 1568-1578 Published online on: 24 March 2015
Article

Mutations in PTF1A are not a common cause for human VATER/VACTERL association or neural tube defects mirroring Danforth's short tail mouse

Nirmala Gurung, Greta Grosse, Markus Draaken, Alina C. Hilger, Nuzhat Nauman, Andreas Müller, Ulrich Gembruch, Waltraut M. Merz, Heiko Reutter, Michael Ludwig

Pages: 1579-1583 Published online on: 13 March 2015
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Serum microRNA-125a-5p, a useful biomarker in liver diseases, correlates with disease progression

Jianjian Zheng, Zhenxu Zhou, Ziqiang Xu, Guojun Li, Peihong Dong, Zhanguo Chen, Dezhao Lin, Bicheng Chen, Fujun Yu

Pages: 1584-1590 Published online on: 24 March 2015
Article

Ser49Gly polymorphism in the β-adrenergic receptor 1 gene in a population sample from Rio de Janeiro state, Brazil, stratified by self-identified skin color and genetic ancestry

Kelly T. Santos, Rossana G.A. De Freitas, Fernanda S.N. Manta, Elizeu F. De Carvalho, Dayse A. Silva

Pages: 1591-1597 Published online on: 24 March 2015
Article

Effects of cinobufacini injection on cell proliferation and the expression of topoisomerases in human HepG‑2 hepatocellular carcinoma cells

Ying Liu, Li‑Ying Ban, Xi Su, Shan Gao, Ji‑Wei Liu, Xiao‑Nan Cui

Pages: 1598-1604 Published online on: 26 March 2015
Journal Cover

July-2015
Volume 12 Issue 1

Print ISSN: 1791-2997
Online ISSN: 1791-3004

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