Journal Articles

Article Open Access

Gene expression profile in human induced pluripotent stem cells: Chondrogenic differentiation in vitro, part A

Wiktoria Maria Suchorska, Ewelina Augustyniak, Magdalena Richter, Tomasz Trzeciak

Pages: 2387-2401 Published online on: 16 March 2017
Article Open Access

Gene expression profile in human induced pluripotent stem cells: Chondrogenic differentiation in vitro, part B

Ewelina Augustyniak, Wiktoria Maria Suchorska, Tomasz Trzeciak, Magdalena Richter

Pages: 2402-2414 Published online on: 16 March 2017
Article Open Access

Matrine reduces the proliferation of A549 cells via the p53/p21/PCNA/eIF4E signaling pathway

Zhiyan Lu, Youzhang Xiao, Xing Liu, Zaipeng Zhang, Feng Xiao, Yongyi Bi

Pages: 2415-2422 Published online on: 16 March 2017
Article Open Access

Wnt-β-catenin signaling pathway inhibition by sclerostin may protect against degradation in healthy but not osteoarthritic cartilage

Jiang Wu, Long Ma, Long Wu, Qunhua Jin

Pages: 2423-2432 Published online on: 03 March 2017
Article Open Access

Correlation of the expression of YY1 and Fas cell surface death receptor with apoptosis of peripheral blood mononuclear cells, and the development of multiple organ dysfunction in children with sepsis

Judith Reséndiz‑Martínez, Juan Asbun‑Bojalil, Sara Huerta‑Yepez, Mario Vega

Pages: 2433-2442 Published online on: 09 March 2017
Article Open Access

Dental and periodontal phenotypes of Dlx2 overexpression in mice

Jiewen Dai, Jiawen Si, Ningjuan Ouyang, Jianfei Zhang, Dandan Wu, Xudong Wang, Guofang Shen

Pages: 2443-2450 Published online on: 10 March 2017
Article Open Access

miR-181a modulates proliferation, migration and autophagy in AGS gastric cancer cells and downregulates MTMR3

Yong Lin, Jing Zhao, Hong Wang, Jie Cao, Yuqiang Nie

Pages: 2451-2456 Published online on: 07 March 2017
Article Open Access

Tenascin-C expression and its associated pathway in BMSCs following co-culture with mechanically stretched ligament fibroblasts

Bing Zhao, Mengcai Hu, Huiyan Wu, Chenchen Ren, Jianshe Wang, Shihong Cui

Pages: 2465-2472 Published online on: 15 March 2017
Article Open Access

Vitamin K2 promotes mesenchymal stem cell differentiation by inhibiting miR‑133a expression

Yuelei Zhang, Shiyang Weng, Junhui Yin, Hao Ding, Changqing Zhang, Youshui Gao

Pages: 2473-2480 Published online on: 09 March 2017
Article Open Access

Tetramethylpyrazine-mediated regulation of CXCR4 in retinoblastoma is sensitive to cell density

Nandan Wu, Lijun Xu, Ying Yang, Na Yu, Zhang Zhang, Pei Chen, Jing Zhang, Mingjun Tang, Meng Yuan, Jian Ge, Keming Yu, Jing Zhuang

Pages: 2481-2488 Published online on: 07 March 2017
Article Open Access

A three-caller pipeline for variant analysis of cancer whole-exome sequencing data

Ze‑Kun Liu, Yu‑Kui Shang, Zhi‑Nan Chen, Huijie Bian

Pages: 2489-2494 Published online on: 16 March 2017
Article Open Access

Plasma microRNA-451 as a novel hemolytic marker for β0-thalassemia/HbE disease

Kamonlak Leecharoenkiat, Yuka Tanaka, Yasuko Harada, Porntip Chaichompoo, Orawan Sarakul, Yasunobu Abe, Duncan Richard Smith, Suthat Fucharoen, Saovaros Svasti, Tsukuru Umemura

Pages: 2495-2502 Published online on: 15 March 2017
Article Open Access

Mice endometrium receptivity in early pregnancy is impaired by maternal hyperinsulinemia

Runqin Li, Juan Wu, Junlin He, Yingxiong Wang, Xueqing Liu, Xuemei Chen, Chao Tong, Yubin Ding, Yan Su, Wenqi Chen, Chen Zhang, Rufei Gao

Pages: 2503-2510 Published online on: 14 March 2017
Article Open Access

Islet-1 induces the differentiation of mesenchymal stem cells into cardiomyocyte-like cells through the regulation of Gcn5 and DNMT-1

Qin Yi, Hao Xu, Ke Yang, Yue Wang, Bin Tan, Jie Tian, Jing Zhu

Pages: 2511-2520 Published online on: 16 March 2017
Article Open Access

p75 neurotrophin receptor: A potential surface marker of tongue squamous cell carcinoma stem cells

Dongdong Tong, Jing Sun, Ping Huang, Minqi Li, Fenghe Zhang

Pages: 2521-2529 Published online on: 07 March 2017
Article Open Access

High mobility group box 1 induces calcification of aortic valve interstitial cells via toll-like receptor 4

Wenjun Shen, Jianqing Zhou, Chaoyang Wang, Guangze Xu, Ying Wu, Zhaohui Hu

Pages: 2530-2536 Published online on: 03 March 2017
Article Open Access

Bone morphogenetic protein 9 stimulates callus formation in osteoporotic rats during fracture healing

Xing Wang, Jun Huang, Fan Huang, Jian‑Chun Zong, Xi Tang, Yang Liu, Qiong‑Fang Zhang, Yang Wang, Liang Chen, Liang‑Jun Yin, Bai‑Cheng He, Zhong‑Liang Deng

Pages: 2537-2545 Published online on: 09 March 2017
Article Open Access

Expression of mTOR/70S6K signaling pathway in pathological scar fibroblasts and the effects of resveratrol intervention

Zhi-Ming Tang, Xiao-Xiang Zhai, Ji-Cun Ding

Pages: 2546-2550 Published online on: 16 March 2017
Article Open Access

Biological effects of bone marrow mesenchymal stem cells on hepatitis B virus in vitro

Wei‑Ping Zheng, Bo‑Ya Zhang, Zhong‑Yang Shen, Ming‑Li Yin, Yi Cao, Hong‑Li Song

Pages: 2551-2559 Published online on: 15 March 2017
Article Open Access

Molecular mechanism of smurf2 in regulating the expression of SnoN in diabetic nephropathy

Zhuojia Xu, Zongli Diao, Ruixia Liu, Wenhu Liu

Pages: 2560-2566 Published online on: 09 March 2017
Article Open Access

High expression of ubiquitin-specific peptidase 39 is associated with the development of vascular remodeling

Shuai He, Wei Zhong, Li Yin, Yifei Wang, Zhibing Qiu, Gang Song

Pages: 2567-2573 Published online on: 08 March 2017
Article Open Access

Telmisartan suppresses cardiac hypertrophy by inhibiting cardiomyocyte apoptosis via the NFAT/ANP/BNP signaling pathway

Xiurong Li, Yuhuai Lan, Yan Wang, Minghao Nie, Yanhong Lu, Eryang Zhao

Pages: 2574-2582 Published online on: 14 March 2017
Article Open Access

Negative regulation of ERK1/2 by PI3K is required for the protective effects of Pyropia yezoensis peptide against perfluorooctane sulfonate-induced endoplasmic reticulum stress

Jeong Hwan Oh, Eun‑Young Kim, Youn Hee Choi, Taek‑Jeong Nam

Pages: 2583-2587 Published online on: 03 March 2017
Article Open Access

Pioglitazone ameliorates Aβ42 deposition in rats with diet-induced insulin resistance associated with AKT/GSK3β activation

Sisi Yang, Zhe Chen, Ming Cao, Renjie Li, Zhigang Wang, Muxun Zhang

Pages: 2588-2594 Published online on: 16 March 2017
Article Open Access

PAR1‑mediated c‑Jun activation promotes heat stress‑induced early stage apoptosis of human umbilical vein endothelial cells

Shuang Zhang, Yanan Liu, Zhenglian Wang, Jingxian Liu, Zhengtao Gu, Qiulin Xu, Lei Su

Pages: 2595-2603 Published online on: 09 March 2017
Article Open Access

Vatalanib, a tyrosine kinase inhibitor, decreases hepatic fibrosis and sinusoidal capillarization in CCl4-induced fibrotic mice

Ling‑Jian Kong, Hao Li, Ya‑Ju Du, Feng‑Hua Pei, Ying Hu, Liao‑Liao Zhao, Jing Chen

Pages: 2604-2610 Published online on: 15 March 2017
Article Open Access

Toxicity study of oxalicumone A, derived from a marine-derived fungus Penicillium oxalicum, in cultured renal epithelial cells

Si Shi, Kunbin Guo, Xiangyu Wang, Hao Chen, Jianbin Min, Shuhua Qi, Wei Zhao, Weirong Li

Pages: 2611-2619 Published online on: 03 March 2017
Article

Antitumor activity of fucoidan in anaplastic thyroid cancer via apoptosis and anti-angiogenesis

Hong‑Yan Shen, Lan‑Zhen Li, Ke‑Cheng Xue, Dan‑Dan Hu, Yu‑Jun Gao

Pages: 2620-2624 Published online on: 16 March 2017
Article

Repression of the expression of TET2 by ZEB1 contributes to invasion and growth in glioma cells

Bo Chen, Yanqing Lei, Hongquan Wang, Yanwei Dang, Peihai Fang, Jun Wang, Jinbo Yang, Lijun Liu

Pages: 2625-2632 Published online on: 03 March 2017
Article

Knockdown of ZFPL1 results in increased autophagy and autophagy‑related cell death in NCI‑N87 and BGC‑823 human gastric carcinoma cell lines

Yong‑Zheng Xie, Wan‑Li Ma, Ji‑Ming Meng, Xue‑Qun Ren

Pages: 2633-2642 Published online on: 09 March 2017
Article

Alleviative effect of grape seed proanthocyanidin extract on small artery vascular remodeling in spontaneous hypertensive rats via inhibition of collagen hyperplasia

Ying Liang, Haiqing Gao, Jian Wang, Quanzhen Wang, Shaohua Zhao, Jun Zhang, Jie Qiu

Pages: 2643-2652 Published online on: 07 March 2017
Article

Lycium barbarum polysaccharide exhibits cardioprotection in an experimental model of ischemia-reperfusion damage

Ya‑Min Hou, Jie Wang, Xian‑Zhao Zhang

Pages: 2653-2658 Published online on: 07 March 2017
Article

Binding of circulating anti-MUC1 antibody and serum MUC1 antigen in stage IV breast cancer

Yan Tang, Xiuxia Cui, Han Xiao, Shengkun Qi, Xiaoping Hu, Qiong Yu, Guang Shi, Xue Zhang, Jiaying Gu, Yongli Yu, Liying Wang, Yarong Li

Pages: 2659-2664 Published online on: 15 March 2017
Article

Wiryeongtang regulates hypertonicity-induced expression of aquaporin-2 water channels in mIMCD-3 cells

Mi Gyeong Kim, Yun Jung Lee, Eun Sik Choi, Jung Joo Yoon, Byung Hyuk Han, Dae Gill Kang, Ho Sub Lee

Pages: 2665-2672 Published online on: 07 March 2017
Article

Advanced glycation end products‑induced mitochondrial energy metabolism dysfunction alters proliferation of human umbilical vein endothelial cells

Yuan Li, Ye Chang, Ning Ye, Yintao Chen, Naijin Zhang, Yingxian Sun

Pages: 2673-2680 Published online on: 10 March 2017
Article

Effect of isosecotanapartholide isolated from Artemisia princeps Pampanini on IL‑33 production and STAT‑1 activation in HaCaT keratinocytes

Chang Taek Oh, Yu‑Jin Jang, Tae‑Rin Kwon, Songi Im, Soon Re Kim, Joon Seok, Gun‑Yong Kim, Young‑Heui Kim, Seog Kyun Mun, Beom Joon Kim

Pages: 2681-2688 Published online on: 09 March 2017
Article

Effects of gap junction intercellular communication on the docetaxel-induced cytotoxicity in rat hepatocytes

Nan Tang, Jinghua Liu, Bo Chen, Yuan Zhang, Meiling Yu, Ziqing Cai, Hongpeng Chen

Pages: 2689-2694 Published online on: 07 March 2017
Article

17β-estradiol protects against doxorubicin-induced cardiotoxicity in male Sprague-Dawley rats by regulating NADPH oxidase and apoptosis genes

Xiao‑Juan Zhang, Xiao‑Qing Cao, Chun‑Sheng Zhang, Zhuo Zhao

Pages: 2695-2702 Published online on: 16 March 2017
Article

BmK CT and 125I-BmK CT suppress the invasion of glioma cells in vitro via matrix metalloproteinase-2

Na Sun, Lingzhou Zhao, Wenli Qiao, Yan Xing, Jinhua Zhao

Pages: 2703-2708 Published online on: 03 March 2017
Article

Upregulation of RASAL2 promotes proliferation and metastasis, and is targeted by miR-203 in hepatocellular carcinoma

Jian‑Feng Fang, Hai‑Ping Zhao, Zheng‑Fei Wang, Shu‑Sen Zheng

Pages: 2720-2726 Published online on: 14 March 2017
Article

Association between myocardial cell apoptosis and calpain-1/caspase-3 expression in rats with hypoxic-ischemic brain damage

Hong Zhao, Mei Xu, Guilan Chu

Pages: 2727-2731 Published online on: 16 March 2017
Article

Inhibition of aldose reductase ameliorates ethanol‑induced steatosis in HepG2 cells

Longxin Qiu, Chengchao Cai, Xiangqian Zhao, Yan Fang, Weibiao Tang, Chang Guo

Pages: 2732-2736 Published online on: 10 March 2017
Article

Hepatocyte growth factor inhibits tubular epithelial‑myofibroblast transdifferentiation by suppression of angiotensin II via the JAK2/STAT3 signaling pathway

Hong‑Yue Wang, Chen Zhang, Qing‑Fei Xiao, Hai‑Chuan Dou, Yan Chen, Chun‑Mei Gu, Ming‑Ji Cui

Pages: 2737-2743 Published online on: 09 March 2017
Article

Role of histone deacetylase expression levels and activity in the inflammatory responses of patients with chronic hepatitis B

Haiyue Zhang, Xun Li, Qian Zhang, Fan Yang, Xiaogang Chu, Di Zhang, Luwen Wang, Zuojiong Gong

Pages: 2744-2752 Published online on: 07 March 2017
Article

Sevoflurane anesthesia in pregnant rats negatively affects nerve function in offspring potentially via inhibition of the Wnt/β-catenin pathway

Yiyao Wang, Yu Li, Qunzhi Xing, Xuechan G. Han, Xu Dong, Yiping Lu, Mintao Zhou

Pages: 2753-2759 Published online on: 13 March 2017
Article

Novel compound heterozygous PLEC mutations lead to early‑onset limb‑girdle muscular dystrophy 2Q

Jingzi Zhong, Gang Chen, Yiwu Dang, Haixia Liao, Jiapeng Zhang, Dan Lan

Pages: 2760-2764 Published online on: 09 March 2017
Article Open Access

Berberine protects against diet-induced obesity through regulating metabolic endotoxemia and gut hormone levels

Jian Hui Xu, Xing Zhen Liu, Wei Pan, Da Jin Zou

Pages: 2765-2787 Published online on: 14 March 2017
Article

High glucose promotes the osteogenic differentiation capability of human periodontal ligament fibroblasts

Sujiwan Seubbuk, Hathaitip Sritanaudomchai, Julalux Kasetsuwan, Rudee Surarit

Pages: 2788-2794 Published online on: 16 March 2017
Article

Neural precursor cell expressed, developmentally downregulated 8‑activating enzyme inhibitor MLN4924 sensitizes colorectal cancer cells to oxaliplatin by inducing DNA damage, G2 cell cycle arrest and apoptosis

Wanwei Zheng, Zhongguang Luo, Jun Zhang, Pei Min, Wenshuai Li, Diannan Xu, Ziqiang Zhang, Panpan Xiong, Hong Liang, Jie Liu

Pages: 2795-2801 Published online on: 09 March 2017
Article

Expression levels of resistant genes affect cervical cancer prognosis

Fengmei Yang, Bo Gao, Rui Li, Wencui Li, Wei Chen, Zongtao Yu, Jicai Zhang

Pages: 2802-2806 Published online on: 15 March 2017
Article

Investigation of hypoglycemic, hypolipidemic and anti‑nephritic activities of Paecilomyces tenuipesN45 in diet/streptozotocin‑induced diabetic rats

Chungang Liu, Xuerui Zeng, Yi Li, Hongli Ma, Jingjing Song, Yuhuan Li, Yulin Zhou, Robert J. Lee, Di Wang

Pages: 2807-2813 Published online on: 10 March 2017
Article

Deep sea water improves hypercholesterolemia and hepatic lipid accumulation through the regulation of hepatic lipid metabolic gene expression

Kyu‑Shik Lee, So‑Young Chun, Yun‑Suk Kwon, Soyoung Kim, Kyung‑Soo Nam

Pages: 2814-2822 Published online on: 13 March 2017
Article

Diosgenin inhibits angiotensin II-induced extracellular matrix remodeling in cardiac fibroblasts through regulating the TGF‑β1/Smad3 signaling pathway

Hong‑Tao Zhou, Xue‑Fang Yu, Gui‑Ming Zhou

Pages: 2823-2828 Published online on: 03 March 2017
Article

Molecular characterization of metastatic osteosarcoma: Differentially expressed genes, transcription factors and microRNAs

Lisong Heng, Zhen Jia, Jie Bai, Kun Zhang, Yangjun Zhu, Jianbing Ma, Jun Zhang, Honghao Duan

Pages: 2829-2836 Published online on: 03 March 2017
Article

MicroRNA-1 upregulation promotes myocardiocyte proliferation and suppresses apoptosis during heart development

Liping Liu, Yonghua Yuan, Xuehua He, Xiaohui Xia, Xiaoyang Mo

Pages: 2837-2842 Published online on: 03 March 2017
Article

Prevalence and genotypic distribution of GB virus C and torque teno virus among patients undergoing hemodialysis

Hanggoro Tri Rinonce, Yoshihiko Yano, Takako Utsumi, Didik Setyo Heriyanto, Nungki Anggorowati, Dewiyani Indah Widasari, Ahmad Ghozali, Totok Utoro, Maria Inge Lusida, Soetjipto, Heru Prasanto, Yoshitake Hayashi

Pages: 2843-2852 Published online on: 03 March 2017
Article

Icariin inhibits MMP‑1, MMP‑3 and MMP‑13 expression through MAPK pathways in IL‑1β‑stimulated SW1353 chondrosarcoma cells

Li Zeng, Xiao‑Feng Rong, Rong‑Heng Li, Xing‑Ye Wu

Pages: 2853-2858 Published online on: 10 March 2017
Article

Clinical significance of inflammatory cytokine and chemokine expression in hand, foot and mouth disease

Ping Shao, Xiaoxin Wu, Hongbo Li, Zhigang Wu, Zongxin Yang, Hangping Yao

Pages: 2859-2866 Published online on: 15 March 2017
Article

Effects of endoplasmic reticulum stress on apoptosis induction in radioresistant macrophages

Hironori Yoshino, Yu Kumai, Ikuo Kashiwakura

Pages: 2867-2872 Published online on: 08 March 2017
Article

Calyptranthes grandifolia O.Berg (Myrtaceae) ethanolic extract inhibits TNF-α gene expression and cytokine release in vitro

Geórgia Muccillo Dexheimer, Luciana Knabben de Oliveira Becker Delving, Henrique Sulzbach de Oliveira, Vanderlei Biolchi, Márcia Inês Goettert, Adriane Pozzobon

Pages: 2873-2880 Published online on: 14 March 2017
Article

Inhibition of heat shock protein 70 intensifies heat-stressed damage and apoptosis of chicken primary myocardial cells in vitro

Jiao Xu, Shu Tang, Erbao Song, Bin Yin, Endong Bao

Pages: 2881-2889 Published online on: 16 March 2017
Article

Cyclic compression stimulates osteoblast differentiation via activation of the Wnt/β-catenin signaling pathway

Xi Chen, Jianmin Guo, Yu Yuan, Zhongguang Sun, Binglin Chen, Xiaoyang Tong, Lingli Zhang, Chao Shen, Jun Zou

Pages: 2890-2896 Published online on: 15 March 2017
Retraction Open Access

[Retracted] Regulatory T cells exhibit neuroprotective effect in a mouse model of traumatic brain injury

Yunhu Yu, Fang Cao, Qishan Ran, Xiaochuan Sun

Pages: 2897-2897 Published online on: 08 March 2017
Review

Role of autophagy in advanced atherosclerosis (Review)

Yu‑Ning Zhu, Wen‑Jing Fan, Chi Zhang, Fang Guo, Wei Li, Yu‑Fei Wang, Zhi‑Sheng Jiang, Shun‑Lin Qu

Pages: 2903-2908 Published online on: 28 March 2017
Review

Viral and host factors associated with outcomes of hepatitis C virus infection (Review)

Zehui Yan, Yuming Wang

Pages: 2909-2924 Published online on: 22 March 2017
Review

iRGD as a tumor‑penetrating peptide for cancer therapy (Review)

Hong Yin, Jie Yang, Qing Zhang, Haiyu Wang, Jinjing Xu, Junnian Zheng

Pages: 2925-2930 Published online on: 30 March 2017
Review Open Access

Clinical significance of sCD163 and its possible role in asthma (Review)

Yue Zhi, Peng Gao, Xiuqin Xin, Wei Li, Lei Ji, Lin Zhang, Xueyang Zhang, Jie Zhang

Pages: 2931-2939 Published online on: 24 March 2017
Article Open Access

Comparative evaluation of the effects of platelet‑rich plasma formulations on extracellular matrix formation and the NF‑κB signaling pathway in human articular chondrocytes

Wenjing Yin, Haitao Xu, Jiagen Sheng, Zhengliang Xu, Xuetao Xie, Changqing Zhang

Pages: 2940-2948 Published online on: 23 March 2017
Article Open Access

Novel therapeutic effects of sesamin on diabetes-induced cardiac dysfunction

Tran Duong Thuy, Nam Nhut Phan, Chih-Yang Wang, Han-Gang Yu, Shu-Yin Wang, Pung-Ling Huang, Yi-Yin Do, Yen-Chang Lin

Pages: 2949-2956 Published online on: 30 March 2017
Article Open Access

Comparison of the PI3KCA pathway in circulating tumor cells and corresponding tumor tissue of patients with metastatic breast cancer

Maren Bredemeier, Sabine Kasimir‑Bauer, Hans‑Christian Kolberg, Thomas Herold, Sarah Synoracki, Siegfried Hauch, Philippos Edimiris, Agnes Bankfalvi, Mitra Tewes, Rainer Kimmig, Bahriye Aktas

Pages: 2957-2968 Published online on: 30 March 2017
Article Open Access

ORMDL3 is associated with airway remodeling in asthma via the ERK/MMP-9 pathway

Fei Yu, Yan Sun, Jiachen Yu, Zhen Ding, Jinrong Wang, Lanyun Zhang, Tiejing Zhang, Yun Bai, Yulin Wang

Pages: 2969-2976 Published online on: 30 March 2017
Article Open Access

Identification of two novel mutations in the SLCO2A1 prostaglandin transporter gene in a Chinese patient with primary hypertrophic osteoarthropathy

Ting Guo, Kai Yang, Lv Liu, Zhi‑Ping Tan, Hong Luo

Pages: 2977-2982 Published online on: 24 March 2017
Article Open Access

Expression levels of transcription factors c-Fos and c-Jun and transmembrane protein HAb18G/CD147 in urothelial carcinoma of the bladder

Muren Huhe, Shuangshuang Liu, Yang Zhang, Zheng Zhang, Zhinan Chen

Pages: 2991-3000 Published online on: 30 March 2017
Article Open Access

Protection of FK506 against neuronal apoptosis and axonal injury following experimental diffuse axonal injury

Ting‑Qin Huang, Jin‑Ning Song, Feng‑Wei Zheng, Hong‑Gang Pang, Yong‑Lin Zhao, Hua Gu, Jun‑Jie Zhao

Pages: 3001-3010 Published online on: 22 March 2017
Article Open Access

Duration of simulated microgravity affects the differentiation of mesenchymal stem cells

Li Xue, Yaohui Li, Jun Chen

Pages: 3011-3018 Published online on: 22 March 2017
Article Open Access

AhR‑E2F1‑KGFR signaling is involved in KGF‑induced intestinal epithelial cell proliferation

Kunqiu Yang, Jiuheng Yin, Baifa Sheng, Qimeng Wang, Bin Han, Aimin Pu, Min Yu, Lihua Sun, Weidong Xiao, Hua Yang

Pages: 3019-3026 Published online on: 23 March 2017
Article Open Access

Cibotium barometz polysaccharides stimulate chondrocyte proliferation in vitro by promoting G1/S cell cycle transition

Changlong Fu, Chunsong Zheng, Jie Lin, Jinxia Ye, Yangyang Mei, Caibin Pan, Guangwen Wu, Xihai Li, Hongzhi Ye, Xianxiang Liu

Pages: 3027-3034 Published online on: 30 March 2017
Article Open Access

The role of miR‑370 in fibrosis after myocardial infarction

Hui Yuan, Jie Gao

Pages: 3041-3047 Published online on: 27 March 2017
Article Open Access

Lentivirus‑mediated overexpression of CD97/ADGRE5 reverses dysregulated high glucose‑induced endothelial cell migration

Wenting Zhao, Zhen Wang, Zewei Sun, Shuai Wang, Mingjie Wu, Liangrong Zheng

Pages: 3048-3054 Published online on: 30 March 2017
Article Open Access

Reduction of miR‑132‑3p contributes to gastric cancer proliferation by targeting MUC13

Liang He, Linlin Qu, Lijing Wei, Yan Chen, Jian Suo

Pages: 3055-3061 Published online on: 22 March 2017
Article Open Access

HMGB1 induces lung fibroblast to myofibroblast differentiation through NF‑κB‑mediated TGF‑β1 release

Qiong Wang, Jun Wang, Junfang Wang, Shanchao Hong, Feifei Han, Jingyu Chen, Guoqian Chen

Pages: 3062-3068 Published online on: 23 March 2017
Article Open Access

GPR143 mutations in Chinese patients with ocular albinism type 1

Xiuhua Jia, Jin Yuan, Xiaoyun Jia, Shiqi Ling, Shiqiang Li, Xiangming Guo

Pages: 3069-3075 Published online on: 23 March 2017
Article Open Access

Low shear stress‑induced autophagy alleviates cell apoptosis in HUVECs

Guo Dong, Shusen Yang, Xuefei Cao, Nannan Yu, Jiangbo Yu, Xiufen Qu

Pages: 3076-3082 Published online on: 28 March 2017
Article

2‑Deoxy‑D‑glucose initiates hepatocyte differentiation in human induced pluripotent stem cells

Minoru Tomizawa, Fuminobu Shinozaki, Yasufumi Motoyoshi, Takao Sugiyama, Shigenori Yamamoto, Naoki Ishige

Pages: 3083-3087 Published online on: 28 March 2017
Article

Oncostatin M in William's E medium is suitable for initiation of hepatocyte differentiation in human induced pluripotent stem cells

Minoru Tomizawa, Fuminobu Shinozaki, Yasufumi Motoyoshi, Takao Sugiyama, Shigenori Yamamoto, Naoki Ishige

Pages: 3088-3092 Published online on: 28 March 2017
Article

Cerebral hemorrhage therapy by targeting VEGF and HGF in a preclinical trial in rats

Xueqing Li, Ruiqi Cao, Huaihai Lu, Wenbin Tian, Ning Yu, Pei Zhang, Zhenming Dong

Pages: 3093-3098 Published online on: 22 March 2017
Article

Increased phosphorylation of 4E‑binding protein 1 predicts poor prognosis for patients with colorectal cancer

Yufeng Miao, Lige Chen, Cuifen Shi, Rengen Fan, Ping Chen, Hongqi Liu, Aihua Xia, Haixin Qian

Pages: 3099-3104 Published online on: 22 March 2017
Article

Effects of GSK2606414 on cell proliferation and endoplasmic reticulum stress‑associated gene expression in retinal pigment epithelial cells

Xintong Jiang, Yantao Wei, Ting Zhang, Zhaotian Zhang, Suo Qiu, Xuezhi Zhou, Shaochong Zhang

Pages: 3105-3110 Published online on: 30 March 2017
Article

Identification of proteins in the aqueous humor associated with cataract development using iTRAQ methodology

Minhong Xiang, Xingru Zhang, Qingsong Li, Hanmin Wang, Zhenyong Zhang, Zhumei Han, Meiqing Ke, Xingxing Chen

Pages: 3111-3120 Published online on: 21 March 2017
Article

Protective effects of oleanolic acid on oxidative stress and the expression of cytokines and collagen by the AKT/NF‑κB pathway in silicotic rats

Hai‑Bing Peng, Rui‑Xun Wang, Hai‑Jing Deng, Yong‑Heng Wang, Jun‑Dong Tang, Fu‑Yuan Cao, Jian‑Hui Wang

Pages: 3121-3128 Published online on: 28 March 2017
Article

LncRNA‑mediated SIRT1/FoxO3a and SIRT1/p53 signaling pathways regulate type II alveolar epithelial cell senescence in patients with chronic obstructive pulmonary disease

Chao Gu, Yaqing Li, Jialiang Liu, Xiwang Ying, Yuanshun Liu, Jianping Yan, Chun Chen, Hongbin Zhou, Liming Cao, Yingyu Ma

Pages: 3129-3134 Published online on: 23 March 2017
Article

Suppression of nuclear factor erythroid‑2‑related factor 2‑mediated antioxidative defense in the lung injury induced by chronic exposure to methamphetamine in rats

Yang Bai, Yun Wang, Ming Liu, Yu‑Han Gu, Bin Jiang, Xu Wu, Huai‑Liang Wang

Pages: 3135-3142 Published online on: 22 March 2017
Article

Inhibitory effect of Angelica gigas on cold‑induced RhoA activation in vascular cells

Kangwook Lee, Min Soo Chae, Sung‑Gook Cho, Ho Yeon Go, Seung‑Ho Sun, Junbock Jang, Ki‑Yong Jung, You‑Kyung Choi, Yun‑Kyung Song, Sung Yong Sim, Hye Lim Lee, Mi Suk Kang, Chan‑Yong Jeon, Seong Gyu Ko

Pages: 3143-3146 Published online on: 28 March 2017
Article

Extravasated platelet aggregation in the livers of rats with drug‑induced hepatic sinusoidal obstruction syndrome

Miki Hirata, Hidehiro Tajima, Tomoharu Miyashita, Takashi Miyata, Shinichi Nakanuma, Isamu Makino, Hironori Hayashi, Katsunobu Oyama, Hiroyuki Takamura, Itasu Ninomiya, Sachio Fushida, Hiroki Nakata, Shoichi Iseki, Shinichi Harada, Tomohiko Wakayama, Tetsuo Ohta

Pages: 3147-3152 Published online on: 28 March 2017
Article

Inhibition of farnesyl pyrophosphate synthase attenuates high glucose‑induced vascular smooth muscle cells proliferation

Guo‑Ping Chen, Xiao‑Qin Zhang, Tao Wu, Jie Han, Dan Ye

Pages: 3153-3160 Published online on: 23 March 2017
Article

Effects of berberine on a rat model of chronic stress and depression via gastrointestinal tract pathology and gastrointestinal flora profile assays

Xiaohui Zhu, Yangdong Sun, Chenggang Zhang, Haifeng Liu

Pages: 3161-3171 Published online on: 22 March 2017
Article

Protective effects of tacrolimus on podocytes in early diabetic nephropathy in rats

Tao Peng, Xiangdi Chang, Jie Wang, Junhui Zhen, Xiangdong Yang, Zhao Hu

Pages: 3172-3178 Published online on: 22 March 2017
Article

Paeoniflorin attenuates the neuroinflammatory response in a rat model of chronic constriction injury

Jianyu Zhou, Jingxia Wang, Wei Li, Chenglong Wang, Li Wu, Jianjun Zhang

Pages: 3179-3185 Published online on: 24 March 2017
Article

Effects of remote ischemic post‑conditioning on fracture healing in rats

Meng Zhou, Shibao Lu, Guowei Lu, Jiang Huang, Limin Liu, Shuai An, Zheng Li, Huiliang Shen

Pages: 3186-3192 Published online on: 22 March 2017
Article

Exome sequencing reveals novel IRXI mutation in congenital heart disease

Changlong Guo, Qidi Wang, Yuting Wang, Liping Yang, Haiyan Luo, Xiao Fang Cao, Lisha An, Yue Qiu, Meng Du, Xu Ma, Hui Li, Cailing Lu

Pages: 3193-3197 Published online on: 30 March 2017
Article

TGFBI gene mutations analysis in Chinese families with corneal dystrophies

Xiaojuan Wang, Ming Ying, Changbo Fu, Yuchuan Wang, Ningdong Li

Pages: 3198-3202 Published online on: 30 March 2017
Article

Detection assay for HPV16 and HPV18 by loop‑mediated isothermal amplification with lateral flow dipstick tests

Ratchanida Kumvongpin, Patcharee Jearanaikoon, Chotchana Wilailuckana, Nattaya Sae‑Ung, Prinya Prasongdee, Sakda Daduang, Metee Wongsena, Patcharee Boonsiri, Wansika Kiatpathomchai, Sukumarn Sanersak Swangvaree, Alisa Sandee, Jureerut Daduang

Pages: 3203-3209 Published online on: 23 March 2017
Article

Imazamethabenz inhibits human breast cancer cell proliferation, migration and invasion via combination with Pin1

Chen Liu, Chaoyu Mu, Zeng Li, Liang Xu

Pages: 3210-3214 Published online on: 28 March 2017
Article

Hypothalamo‑hypophysial system in rats with autotransplantation of the adrenal cortex

Nae Takizawa, Susumu Tanaka, Souichi Oe, Taro Koike, Tadashi Matsuda, Hisao Yamada

Pages: 3215-3221 Published online on: 24 March 2017
Article

Nationwide survey of Baller‑Gerold syndrome in Japanese population

Hideo Kaneko, Rie Izumi, Hirotsugu Oda, Osamu Ohara, Kiyoko Sameshima, Hidenori Ohnishi, Toshiyuki Fukao, Michinori Funato

Pages: 3222-3224 Published online on: 28 March 2017
Article

Effects of autophagy and endocytosis on the activity of matrix metalloproteinase‑2 in human renal proximal tubular cells under hypoxia

Wenmin Yu, Zhi Wang, Yiping Li, Lei Liu, Jing Liu, Fenggan Ding, Xiaoyi Zhang, Zhengyuan Cheng, Pingsheng Chen

Pages: 3225-3230 Published online on: 22 March 2017
Article

Reduced expression of miR‑205‑5p promotes apoptosis and inhibits proliferation and invasion in lung cancer A549 cells by upregulation of ZEB2 and downregulation of erbB3

Min Jiang, Ting Zhong, Wei Zhang, Zuke Xiao, Guozhu Hu, Hong Zhou, Haibin Kuang

Pages: 3231-3238 Published online on: 28 March 2017
Article

Bone marrow mesenchymal stem cells accelerate the hyperglycemic refractory wound healing by inhibiting an excessive inflammatory response

Wenbin Nan, Zhihao Xu, Zhibin Chen, Xin Yuan, Juntang Lin, Huigen Feng, Jie Lian, Hongli Chen

Pages: 3239-3244 Published online on: 28 March 2017
Article

MicroRNA‑499 rs3746444 A/G polymorphism functions as a biomarker to predict recurrence following endoscopic submucosal dissection in primary early gastric cancer

Huiyong Shi, Xiangshan Yang, Yanan Zhen, Shoujun Huo, Ruixue Xiao, Zhongfa Xu

Pages: 3245-3251 Published online on: 23 March 2017
Article

Overexpression of Tim-3 reduces Helicobacter pylori-associated inflammation through TLR4/NFκB signaling in vitro

Fucai Wang, Zhirong Mao, Dongsheng Liu, Jing Yu, Youhua Wang, Wen Ye, Dongjia Lin, Nanjin Zhou, Yong Xie

Pages: 3252-3258 Published online on: 21 March 2017
Article

Role of tropomyosin in silkworm allergy

Kyoung Yong Jeong, In‑Soo Han, June Yong Lee, Kyung Hee Park, Jae‑Hyun Lee, Jung‑Won Park

Pages: 3264-3270 Published online on: 24 March 2017
Article

miR‑217 inhibits osteogenic differentiation of rat bone marrow‑derived mesenchymal stem cells by binding to Runx2

Yu‑Long Zhu, Shui Wang, De‑Gang Ding, Liang Xu, Hai‑Tao Zhu

Pages: 3271-3277 Published online on: 22 March 2017
Article

Extracellular matrix metabolism disorder induced by mechanical strain on human parametrial ligament fibroblasts

Jie Min, Bingshu Li, Cheng Liu, Wenjun Guo, Shasha Hong, Jianming Tang, Li Hong

Pages: 3278-3284 Published online on: 24 March 2017
Article

F221Y mutation in hepatitis B virus reverse transcriptase is associated with hepatocellular carcinoma prognosis following liver resection

Huiming Li, Jian'an Jia, Mengmeng Wang, Hui Wang, Xing Gu, Meng Fang, Chunfang Gao

Pages: 3292-3300 Published online on: 23 March 2017
Article

Chronological changes in the expression of phosphorylated tau and 5‑AMP‑activated protein kinase in the brain of senescence‑accelerated P8 mice

Hak‑Su Kim, Sohee Moon, Sujin Kim, Min‑Jae Lee, Min Hwa Suk, Dong‑Ho Park, Dong Wun Shin, Chang‑Shin Park, Ju‑Hee Kang

Pages: 3301-3309 Published online on: 23 March 2017
Editorial

[Editorial] Environmental and occupational risk factors associated with different pathological conditions

Salvatore Santo Signorelli, Margherita Ferrante

Pages: 3315-3316 Published online on: 29 March 2017
Article

New insights on ‘old’ toxicants in occupational toxicology (Review)

Chiara Costa, Edoardo Miozzi, Michele Teodoro, Giusi Briguglio, Venerando Rapisarda, Concettina Fenga

Pages: 3317-3322 Published online on: 24 March 2017
Article Open Access

Health risk assessment of environmental selenium: Emerging evidence and challenges (Review)

Marco Vinceti, Tommaso Filippini, Silvia Cilloni, Annalisa Bargellini, Anna Valeria Vergoni, Aristides Tsatsakis, Margherita Ferrante

Pages: 3323-3335 Published online on: 24 March 2017
Review Open Access

The risk of HCV infection among health-care workers and its association with extrahepatic manifestations (Review)

Adriana Garozzo, Luca Falzone, Venerando Rapisarda, Andrea Marconi, Diana Cinà, Concettina Fenga, Demetrios A. Spandidos, Massimo Libra

Pages: 3336-3339 Published online on: 24 March 2017
Article

Determinants of serum manganese levels in an Italian population

Tommaso Filippini, Bernhard Michalke, Peter Grill, Carlotta Malagoli, Marcella Malavolti, Luciano Vescovi, Sabina Sieri, Vittorio Krogh, Andrea Cherubini, Giuseppe Maffeis, Roberto Lucchini, Margherita Ferrante, Marco Vinceti

Pages: 3340-3349 Published online on: 24 March 2017
Article

Occupational exposure to Mount Etna's basaltic dust: Assessment of mutagenic and cytotoxic effects

Caterina Ledda, Salvatore Cocuzza, Monica Salerno, Paola Senia, Serena Matera, Venerando Rapisarda, Carla Loreto

Pages: 3350-3354 Published online on: 24 March 2017
Review

Immunological effects of occupational exposure to lead (Review)

Concettina Fenga, Silvia Gangemi, Valentina Di Salvatore, Luca Falzone, Massimo Libra

Pages: 3355-3360 Published online on: 24 March 2017
Article

Lead exposure and plasma mRNA expression in ERBB2 gene

Margherita Ferrante, Caterina Ledda, Gea Oliveri Conti, Maria Fiore, Venerando Rapisarda, Chiara Copat, Giuseppe Sole, Nivea Terzo, Salvatore Travali

Pages: 3361-3365 Published online on: 24 March 2017
Review

Epigenetic alterations and occupational exposure to benzene, fibers, and heavy metals associated with tumor development (Review)

Rossella Salemi, Andrea Marconi, Valentina Di Salvatore, Sabrina Franco, Venerando Rapisarda, Massimo Libra

Pages: 3366-3371 Published online on: 24 March 2017
Article

Immunomodulatory effects in workers exposed to naturally occurring asbestos fibers

Caterina Ledda, Chiara Costa, Serena Matera, Beatrice Puglisi, Valentina Costanzo, Massimo Bracci, Concettina Fenga, Venerando Rapisarda, Carla Loreto

Pages: 3372-3378 Published online on: 24 March 2017
Article

Absence of t(14;18) chromosome translocation in agricultural workers after short-term exposure to pesticides

Venerando Rapisarda, Caterina Ledda, Serena Matera, Lucrezia Fago, Giorgio Arrabito, Luca Falzone, Andrea Marconi, Massimo Libra, Carla Loreto

Pages: 3379-3382 Published online on: 24 March 2017
Article

Iron and Parkinson's disease: A systematic review and meta-analysis

Giovanni Mostile, Calogero Edoardo Cicero, Loretta Giuliano, Mario Zappia, Alessandra Nicoletti

Pages: 3383-3389 Published online on: 24 March 2017
Article

The effects of air pollutants on the mortality rate of lung cancer and leukemia

Mansooreh Dehghani, Laila Keshtgar, Mohammad Reza Javaheri, Zahra Derakhshan, Gea Oliveri Conti, Pietro Zuccarello, Margherita Ferrante

Pages: 3390-3397 Published online on: 24 March 2017
Article Open Access

B(a)P adduct levels and fertility: A cross‑sectional study in a Sicilian population

Gea Oliveri Conti, Aldo Eugenio Calogero, Filippo Giacone, Maria Fiore, Martina Barchitta, Antonella Agodi, Margherita Ferrante

Pages: 3398-3404 Published online on: 27 March 2017
Article

Toenail selenium as an indicator of environmental exposure: A cross-sectional study

Tommaso Filippini, Angela Ferrari, Bernhard Michalke, Peter Grill, Luciano Vescovi, Chiara Salvia, Carlotta Malagoli, Marcella Malavolti, Sabina Sieri, Vittorio Krogh, Annalisa Bargellini, Antonio Martino, Margherita Ferrante, Marco Vinceti

Pages: 3405-3412 Published online on: 24 March 2017
Review

Kidney and heavy metals - The role of environmental exposure (Review)

Paolo Lentini, Luca Zanoli, Antonio Granata, Salvatore Santo Signorelli, Pietro Castellino, Roberto Dell'Aquila

Pages: 3413-3419 Published online on: 24 March 2017
Article

Sclerostin is a possible candidate marker of arterial stiffness: Results from a cohort study in Catania

Agostino Gaudio, Valerio Fiore, Rosario Rapisarda, Maria Helga Sidoti, Anastasia Xourafa, Antonino Catalano, Giovanni Tringali, Luca Zanoli, Salvatore Santo Signorelli, Carmelo Erio Fiore

Pages: 3420-3424 Published online on: 24 March 2017
Article

A systematic review of arterial stiffness, wave reflection and air pollution

Luca Zanoli, Paolo Lentini, Antonio Granata, Agostino Gaudio, Pasquale Fatuzzo, Leonardo Serafino, Stefania Rastelli, Valerio Fiore, Ambra D'Anca, Salvatore Santo Signorelli, Pietro Castellino

Pages: 3425-3429 Published online on: 24 March 2017
Article

Heavy metal content and molecular species identification in canned tuna: Insights into human food safety

Anna Maria Pappalardo, Chiara Copat, Venera Ferrito, Alfina Grasso, Margherita Ferrante

Pages: 3430-3437 Published online on: 24 March 2017
Article

Transition and heavy metals compared to oxidative parameter balance in patients with deep vein thrombosis: A case-control study

Margherita Ferrante, Maria Fiore, Gea Oliveri Conti, Valerio Fiore, Alfina Grasso, Chiara Copat, Salvatore Santo Signorelli

Pages: 3438-3444 Published online on: 24 March 2017
Review

Deep vein thrombosis related to environment (Review)

Salvatore Santo Signorelli, Margherita Ferrante, Agostino Gaudio, Valerio Fiore

Pages: 3445-3448 Published online on: 24 March 2017
Journal Cover

May-2017
Volume 15 Issue 5

Print ISSN: 1791-2997
Online ISSN: 1791-3004

Sign up for eToc alerts

Recommend to Library

Full Size Image